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Mossbourne Community Academy A
Mossbourne Community Academy A

... Complete the diagram to show the chromosomes in one cell that could be produced from the cell in Figure 2 as a result of meiosis. ...
Having it both ways: transcription factors that bind DNA and RNA
Having it both ways: transcription factors that bind DNA and RNA

... proteins that were initially categorized as DNA-binding transcription factors, but for which subsequent research has shown apparent RNA-binding activities and functions (Table 2). With the expectation that such `moonlighting' by DNA-binding proteins might be more common than previously imagined, we ...
View Poster - Technology Networks
View Poster - Technology Networks

... Sequences were mapped back onto the secondary structures and assembled into overlap groups. These had to pass filters including minimum percentage of base-pairing, maximum length of unpaired regions, internal hairpins and maximum length of overlap group. A miRNA candidate locus had to have at least ...
The Topology of the Possible
The Topology of the Possible

... reproducing entities. The research agenda focused on selection aims at characterizing the conditions under which a phenotypic innovation can, once generated, invade an existing population. The classical fields of inquiry concerned with selection are population genetics and ecology. The main variabl ...
Question 1 _____/ 30 points Question 2 _____/ 20 points Question 3
Question 1 _____/ 30 points Question 2 _____/ 20 points Question 3

... The pattern of transcripts would most likely look like wildtype. In this case, the Mediator complex is not being recruited by the activator, rather TFIID is, so phosphorylation of the CTD is not as important for release of RNA Pol II from the promoter. ...
lac
lac

... Regulation of the lac operon involves: Negative control Positive control Cis-acting DNA sequence Trans-acting protein factors ...
Document
Document

... RESULTS Phage proteins remained outside the bacterial cells during infection, while phage DNA entered the cells. When cultured, bacterial cells with radioactive phage DNA released new phages with some radioactive phosphorus. CONCLUSION Hershey and Chase concluded that DNA, not protein, functions as ...
lecture12-motif-finding
lecture12-motif-finding

... Regulatory regions are comprised of “binding sites” “Binding sites” attract a special class of proteins, known as “transcription factors” A TFBS can be located anywhere within the regulatory region (promoter region) Bound transcription factors can also inhibit DNA ...
8.2 Structure of DNA
8.2 Structure of DNA

... more structural genes that code for all the proteins needed to do a job. – Operons are most common in prokaryotes. – The lac operon was one of the first examples of gene regulation to be discovered. – The lac operon has three genes that code for enzymes that break down lactose. ...
ods of time, until activated b), a activated, the I`irtrl DNA hiiacks the
ods of time, until activated b), a activated, the I`irtrl DNA hiiacks the

... polynucleotides is enormous. Looking more closely at our polynucleotide, we see in the center of Figure 10.2A that each nucleotide consists of threq co.mpenents: a nitrogenous base (in DNA, A, C, T, or G), a sugar (blue), and a phosphate group (yellow). The nucleotides are joined to one another by c ...
1. Nucleic Acids and Chromosomes
1. Nucleic Acids and Chromosomes

...  Adenine, guanine, cytosine and thymine bases  Stability: Deoxyribose sugar less reactive because of C-H bonds. Stable in alkaline conditions. Minor groove means harder for enzymes to attack DNA. RNA: A (usually) single-stranded polynucleotide in the form of a chain of covalently linked ribonucleo ...
SUMMARY The steady state kinetics of initiation of T7 DNA transcrip
SUMMARY The steady state kinetics of initiation of T7 DNA transcrip

... schema it is possible that one of the routes if favored under normal conditions, but all of them are principally possible. This would be called a kinetically ordered mechanism. One could also think about "mixed-type" mechanisms, in which substrates bind randomly, while product release is ordered or ...
2: CHEMICAL COMPOSITION OF THE BODY
2: CHEMICAL COMPOSITION OF THE BODY

... bases. Nucleotides are linked together by covalent bonds between the sugar and phosphate groups of adjacent subunits. The three-dimensional structure of DNA is a double helix, with the two strands held together by hydrogen bonds between a purine base on one chain and a pyrimidine base on the other. ...
Preview Sample 2
Preview Sample 2

... bases. Nucleotides are linked together by covalent bonds between the sugar and phosphate groups of adjacent subunits. The three-dimensional structure of DNA is a double helix, with the two strands held together by hydrogen bonds between a purine base on one chain and a pyrimidine base on the other. ...
Archaeal Transcription Initiation - IMBB
Archaeal Transcription Initiation - IMBB

... al., 1996; Grayling et al., 1996). In most cases, the primary sequences of the archaeal histones within one species are more similar to each other than to the sequences of histones in other Archaea, indicating that the original histone gene has undergone different numbers of duplications during the ...
DNA constructs designed to produce short hairpin, interfering RNAs
DNA constructs designed to produce short hairpin, interfering RNAs

... a universal property of eukaryotes (Hannon 2002; Plasterk 2002) and the enzymes involved, e.g. Dicer, are essential for development (Bernstein et al. 2003). The long double-stranded RNA used to induce RNAi in many species provokes a strong cytotoxic response in mammalian cells (Hunter et al. 1975). ...
Review Questions
Review Questions

... ribosome is the site of protein synthesis in a cell. A ribosome has two parts called subunits. When not translating, the small subunit is unattached to the large subunit. During translation, the small subunit will bond to the mRNA and the large subunit bonds to the small subunit cradling the mRNA be ...
No Slide Title
No Slide Title

... The P site tRNA leaves the ribosome The ribosome translocates (moves) the other tRNA from the A site over to the P site This movement then exposes the next mRNA codon to be translated (at the A site) and the process then repeats itself ...
Gene Expression Microarray Analysis of Archival FFPE Samples
Gene Expression Microarray Analysis of Archival FFPE Samples

... frozen tumor tissue. Many laboratories are trying to develop methods to allow a similar degree of gene expression profiling using FFPE samples.3 FFPE samples represent the largest source of archival biological material available for large retrospective prognostic studies of human cancer, with over 4 ...
Slides
Slides

... linkage to a pentose sugar §Ribose (e.g., adenosine) for RNA §Deoxyribose (e.g., deoxyadenosine) for DNA ...
Chapter 15
Chapter 15

... chromatin structure results, allowing for increased transcription ...
Human fetal normal cDNA panel
Human fetal normal cDNA panel

... Intended use of the products: All products sold by AMSBIO are intended for research use only and must not be used for medical diagnostic or drug purposes. AMSBIO products may not resell, modified for resale or used to manufacture commercial products without written approval from AMSBIO. Limited prod ...
TRANSLATION
TRANSLATION

... In codons the third base may differ between 2 codons that code for the same amino acid (UAU and UAC both code for tyrosine). If the tRNA's anticodon is AUA it can still bind to UAC. This flexibility allows for the correct amino acid to be added to the polypeptide chain despite errors in the gene seq ...
Infectious Hematopoietic Necrosis Virus genesig
Infectious Hematopoietic Necrosis Virus genesig

... The linear, single-stranded, negative-sense RNA genome of this virus 11,131 nucleotides long and encodes six genes. Fives of these code for structural proteins while the other codes a nonvirion protein of unknown function. Transmission of this virus usually occurs via contact with infected bodily se ...
5.4 Translation
5.4 Translation

... In codons the third base may differ between 2 codons that code for the same amino acid (UAU and UAC both code for tyrosine). If the tRNA's anticodon is AUA it can still bind to UAC. This flexibility allows for the correct amino acid to be added to the polypeptide chain despite errors in the gene seq ...
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Nucleic acid tertiary structure



The tertiary structure of a nucleic acid is its precise three-dimensional structure, as defined by the atomic coordinates. RNA and DNA molecules are capable of diverse functions ranging from molecular recognition to catalysis. Such functions require a precise three-dimensional tertiary structure. While such structures are diverse and seemingly complex, they are composed of recurring, easily recognizable tertiary structure motifs that serve as molecular building blocks. Some of the most common motifs for RNA and DNA tertiary structure are described below, but this information is based on a limited number of solved structures. Many more tertiary structural motifs will be revealed as new RNA and DNA molecules are structurally characterized.
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