Rfam Documentation
... Our seed alignments are small, curated sets of representative sequences for each family, as opposed to an alignment of all known members. The seed alignment also has as a secondary structure annotation, which represents the conserved secondary structure for these sequences. The ideal basis for a new ...
... Our seed alignments are small, curated sets of representative sequences for each family, as opposed to an alignment of all known members. The seed alignment also has as a secondary structure annotation, which represents the conserved secondary structure for these sequences. The ideal basis for a new ...
The Genetic Basis of Differences in Cation
... recorded (Table 3). Data on the progeny of plasmodia A-C and D-E were analysed separately, as their genetic backgrounds differed (Table 3, see footnote). In plasmodial groups A-C, one parental type (VIII) occurred at 25% of the frequency of the other (I), a result similar to that obtained with the p ...
... recorded (Table 3). Data on the progeny of plasmodia A-C and D-E were analysed separately, as their genetic backgrounds differed (Table 3, see footnote). In plasmodial groups A-C, one parental type (VIII) occurred at 25% of the frequency of the other (I), a result similar to that obtained with the p ...
Nonsensemediated decay of glutathione peroxidase 1 mRNA in the
... codon failed to elicit NMD when the intron was moved either 83 bp upstream or as close as 15 or 43 bp downstream (Figure 1). However, both codons elicited NMD when the intron was moved 59 bp downstream (Figure 1). Notably, the extent of NMD was comparable with the extent when the intron was located ...
... codon failed to elicit NMD when the intron was moved either 83 bp upstream or as close as 15 or 43 bp downstream (Figure 1). However, both codons elicited NMD when the intron was moved 59 bp downstream (Figure 1). Notably, the extent of NMD was comparable with the extent when the intron was located ...
Unconventional initiator tRNAs sustain Escherichia coli
... P-site of the ribosome directly. In contrast, elongator tRNAs first bind the A-site of the ribosome and then get translocated to the P-site. Two special features that have evolved to promote initiator tRNA binding to the P-site in eubacteria are (i) formylation of the methionine amino acid that it ca ...
... P-site of the ribosome directly. In contrast, elongator tRNAs first bind the A-site of the ribosome and then get translocated to the P-site. Two special features that have evolved to promote initiator tRNA binding to the P-site in eubacteria are (i) formylation of the methionine amino acid that it ca ...
Pleiotropic effects of the mouse lethal yellow (Ay) mutation
... Ay is also one of the oldest recognized mutations of the agouti coat color locus, in which alleles associated with the synthesis of yellow pigment in hair follicles are dominant to those associated with the synthesis of black pigment [(reviewed in Silvers (1979)]. Ay in combination with all other ag ...
... Ay is also one of the oldest recognized mutations of the agouti coat color locus, in which alleles associated with the synthesis of yellow pigment in hair follicles are dominant to those associated with the synthesis of black pigment [(reviewed in Silvers (1979)]. Ay in combination with all other ag ...
PDF
... hybridization. Expression was found not only in the central nervous system, as was expected from the expression pattern of the endogenous Ndn gene, but also to be comparatively widespread, suggesting that the promoter region did not contain all of the regulatory control sequences present in the endo ...
... hybridization. Expression was found not only in the central nervous system, as was expected from the expression pattern of the endogenous Ndn gene, but also to be comparatively widespread, suggesting that the promoter region did not contain all of the regulatory control sequences present in the endo ...
arXiv:0708.2724v1 [cond-mat.other] 20 Aug 2007
... There are other important properties that will help us understand the experiments and theoretical proposals below. For instance, a polynucleotide has a global orientation, with one end a 5′ and the other end a 3′ , as described in Fig. 3. We will see in Sec. IV that this is important for the structu ...
... There are other important properties that will help us understand the experiments and theoretical proposals below. For instance, a polynucleotide has a global orientation, with one end a 5′ and the other end a 3′ , as described in Fig. 3. We will see in Sec. IV that this is important for the structu ...
Partial report - GEP Community Server
... below). The blastn alignment placed the TSS of onecut at 21,599. However, there is also an Inr motif at 21,595–21,600. Because the Inr motif is found at -2 of the TSS, the placement of this Inr motif would place the TSS of onecut at 21,598. Examination of the Combined RAMPAGE TSS datasets for D. mel ...
... below). The blastn alignment placed the TSS of onecut at 21,599. However, there is also an Inr motif at 21,595–21,600. Because the Inr motif is found at -2 of the TSS, the placement of this Inr motif would place the TSS of onecut at 21,598. Examination of the Combined RAMPAGE TSS datasets for D. mel ...
Investigating the DNA-Binding Interactions of Small
... Theodore Goodson III for the opportunity. He is one of the few people who has stood up and fought for me. Without him, this would have not been possible. He has provided me the guidance, support, and resources to be successful as a scientist. I will be forever thankful for Prof. Goodson. He will be ...
... Theodore Goodson III for the opportunity. He is one of the few people who has stood up and fought for me. Without him, this would have not been possible. He has provided me the guidance, support, and resources to be successful as a scientist. I will be forever thankful for Prof. Goodson. He will be ...
Cold-induced silencing by long antisense transcripts of an
... demethylase activity of FLOWERING LOCUS D (FLD)5,6. FLC is also repressed by prolonged cold and epigenetically silenced by a Polycomb mechanism involving a PHD–PRC2 (plant homeodomain–Polycomb repressive complex 2) complex2, in a process known as vernalization3,7. To understand the roles of non-codi ...
... demethylase activity of FLOWERING LOCUS D (FLD)5,6. FLC is also repressed by prolonged cold and epigenetically silenced by a Polycomb mechanism involving a PHD–PRC2 (plant homeodomain–Polycomb repressive complex 2) complex2, in a process known as vernalization3,7. To understand the roles of non-codi ...
Biophysics of Macromolecules: Problem set 4
... b) Single layer origami structures are based on parallel DNA double helices that are connected to each other by inter-strand crossovers every 32 bp. As discussed in class, this value was chosen to be approximately commensurable with the helical periodicity of double-stranded DNA in its B form, which ...
... b) Single layer origami structures are based on parallel DNA double helices that are connected to each other by inter-strand crossovers every 32 bp. As discussed in class, this value was chosen to be approximately commensurable with the helical periodicity of double-stranded DNA in its B form, which ...
Diapositiva 1 - Universidad Autónoma de San Luis Potosí
... The three stages Initiation involves the reactions that precede formation of the peptide bond between the first two amino acids of the protein. It requires the ribosome to bind to the mRNA, forming an initiation complex that contains the first aminoacyl-tRNA. This is a relatively slow step in prote ...
... The three stages Initiation involves the reactions that precede formation of the peptide bond between the first two amino acids of the protein. It requires the ribosome to bind to the mRNA, forming an initiation complex that contains the first aminoacyl-tRNA. This is a relatively slow step in prote ...
Presence of multiple group I introns closely 23S rRNAs of lichen-forming
... Relationship between introns at positions L1917, L1931 and L1951 with bacterial group I introns. With respect to host evolution, an examination of the LSU rDNA tree (Fig. 1B) shows that the members of the Trebouxia genus analyzed in this study form two distinct main lineages: lineage 1, defined by T ...
... Relationship between introns at positions L1917, L1931 and L1951 with bacterial group I introns. With respect to host evolution, an examination of the LSU rDNA tree (Fig. 1B) shows that the members of the Trebouxia genus analyzed in this study form two distinct main lineages: lineage 1, defined by T ...
Genome-wide characteristics of sequence coverage by next
... “The most likely explanation for why genes for common diseases have not been found is that, with few exceptions, they do not exist. …., if inherited genes are not to blame for our commonest illnesses, can we find out what is? “ ...
... “The most likely explanation for why genes for common diseases have not been found is that, with few exceptions, they do not exist. …., if inherited genes are not to blame for our commonest illnesses, can we find out what is? “ ...
Binding of Hoechst with nucleic acids using fluorescence spectroscopy
... of Hoechst here was in ~ 1.5 - 2 times less than in the case of HP1 or t-RNA. It means that Hoechst interacts with the double helix not such strong as with single chains or hairpin structures. The life-time of Hoechst at binding with DNA was increased from 0.4 ns to only 3 ns. Furthermore, there was ...
... of Hoechst here was in ~ 1.5 - 2 times less than in the case of HP1 or t-RNA. It means that Hoechst interacts with the double helix not such strong as with single chains or hairpin structures. The life-time of Hoechst at binding with DNA was increased from 0.4 ns to only 3 ns. Furthermore, there was ...
PAX6 mRNA Transcript Analysis in Various Ocular/Non
... a CCAGCATGC translation start site at exon 4, a TAA stop codon in exon 13. The transcription start site and promoter region with TATA, CAAT, and GC regulatory elements, and three possible Submit Manuscript | http://medcraveonline.com ...
... a CCAGCATGC translation start site at exon 4, a TAA stop codon in exon 13. The transcription start site and promoter region with TATA, CAAT, and GC regulatory elements, and three possible Submit Manuscript | http://medcraveonline.com ...
Mutations at the Darkener of apricot Locus Modulate Transcript
... transposon distinct from copia (ZACHARand BINCHAM 1982). T h e Doa product presumably interacts with sequences contained within the transposons inserted at wa and w5Ps5,since white alleles with point mutations do not respond (RABINOW and BIRCHLER 1989). Doa acts upon wa as an inverse function ofits ...
... transposon distinct from copia (ZACHARand BINCHAM 1982). T h e Doa product presumably interacts with sequences contained within the transposons inserted at wa and w5Ps5,since white alleles with point mutations do not respond (RABINOW and BIRCHLER 1989). Doa acts upon wa as an inverse function ofits ...
Horizontal gene transfer from flowering plants to Gnetum
... nosperm-type and angiosperm-type nad1 intron 2 sequences was possible because they possess unique characteristics. The gymnosperm-type nad1 intron 2 in Gnetum is characterized by 37–80 base pairs inserted before the GTGCG motif that is typical of the start of group II introns (Tables 3 and 4 and Fig ...
... nosperm-type and angiosperm-type nad1 intron 2 sequences was possible because they possess unique characteristics. The gymnosperm-type nad1 intron 2 in Gnetum is characterized by 37–80 base pairs inserted before the GTGCG motif that is typical of the start of group II introns (Tables 3 and 4 and Fig ...
Par-1
... Systemic and inherent RNAi Systemic and inherent RNAi is observed in plants and C. elegans, i) RNAi induced in one place can spread to the other places of the body; ii) The RNAi treats can pass through several generations. ...
... Systemic and inherent RNAi Systemic and inherent RNAi is observed in plants and C. elegans, i) RNAi induced in one place can spread to the other places of the body; ii) The RNAi treats can pass through several generations. ...
Modified uridine at wobble position in tRNA of
... Transfer RNAs (tRNAs) are the adaptor molecules that play a critical role in ...
... Transfer RNAs (tRNAs) are the adaptor molecules that play a critical role in ...
Transvection and pairing of a Drosophila Hox long noncoding RNA
... segments (Pattatucci et al. 1991). Strikingly, five different GOF mutations associated with translocations or inversions with breakpoints mapping to the fushi tarazu– Antennapedia (ftz-Antp) interval result in mis-regulation of Scr in trans, on the wildtype (wt) chromosome (Southworth and Kennison 2 ...
... segments (Pattatucci et al. 1991). Strikingly, five different GOF mutations associated with translocations or inversions with breakpoints mapping to the fushi tarazu– Antennapedia (ftz-Antp) interval result in mis-regulation of Scr in trans, on the wildtype (wt) chromosome (Southworth and Kennison 2 ...
... is inhibited. As the ncRNA is not produced maternally, most genes within the domain are free to be expressed from that chromosome (Figure 1). Recent experiments have strongly suggested that the silencing mechanism of Kcnq1ot1 RNA involves a spreading activity in cis, recruitment of Polycomb group pr ...
Comparison of the Collision-Induced Dissociation of Duplex DNA at
... Further complication can also arise from the multiple local minima that can exist in the potential energy landscape of large molecules. The dissociation mechanism can involve multiple intermediates, and a one-step scheme may be too simplistic. Supramolecular assemblies are usually held together by m ...
... Further complication can also arise from the multiple local minima that can exist in the potential energy landscape of large molecules. The dissociation mechanism can involve multiple intermediates, and a one-step scheme may be too simplistic. Supramolecular assemblies are usually held together by m ...
Pdf - Text of NPTEL IIT Video Lectures
... The content of parental D N A in double helix decreases with each generation according to the semi-conservative model of replication. Each parental strand acts as a template for the synthesis of new strand of D N A, which is complementary to the parental strand. Each daughter D N A molecule always ...
... The content of parental D N A in double helix decreases with each generation according to the semi-conservative model of replication. Each parental strand acts as a template for the synthesis of new strand of D N A, which is complementary to the parental strand. Each daughter D N A molecule always ...
Nucleic acid tertiary structure
The tertiary structure of a nucleic acid is its precise three-dimensional structure, as defined by the atomic coordinates. RNA and DNA molecules are capable of diverse functions ranging from molecular recognition to catalysis. Such functions require a precise three-dimensional tertiary structure. While such structures are diverse and seemingly complex, they are composed of recurring, easily recognizable tertiary structure motifs that serve as molecular building blocks. Some of the most common motifs for RNA and DNA tertiary structure are described below, but this information is based on a limited number of solved structures. Many more tertiary structural motifs will be revealed as new RNA and DNA molecules are structurally characterized.