NA stabilization
... The unstaking of the single stranded poly A by heat is a noncooperative conformational change The stacking is very specific to the bases and the hydrophobic interactions responsible for this interaction is poorly understood ...
... The unstaking of the single stranded poly A by heat is a noncooperative conformational change The stacking is very specific to the bases and the hydrophobic interactions responsible for this interaction is poorly understood ...
Nucleic acid tertiary structure
The tertiary structure of a nucleic acid is its precise three-dimensional structure, as defined by the atomic coordinates. RNA and DNA molecules are capable of diverse functions ranging from molecular recognition to catalysis. Such functions require a precise three-dimensional tertiary structure. While such structures are diverse and seemingly complex, they are composed of recurring, easily recognizable tertiary structure motifs that serve as molecular building blocks. Some of the most common motifs for RNA and DNA tertiary structure are described below, but this information is based on a limited number of solved structures. Many more tertiary structural motifs will be revealed as new RNA and DNA molecules are structurally characterized.