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... the target sequence ...
Curriculum and Training Specialist Bio
Curriculum and Training Specialist Bio

... the target sequence ...
NATIONAL UNIVERSITY OF SINGAPORE DEPARTMENT OF BIOLOGICAL SCIENCES ADVANCED PLACEMENT TEST
NATIONAL UNIVERSITY OF SINGAPORE DEPARTMENT OF BIOLOGICAL SCIENCES ADVANCED PLACEMENT TEST

12.3 Transcription and Translation PPT
12.3 Transcription and Translation PPT

... The genetic code is written in a language that only has four letters: A,U,G &C! These letters (nucleotides) combine in different ways to form the code for twenty different amino acids. The genetic code is read three letters (nucleotides) at a time in groups called codons. ...
Genetics Assessment
Genetics Assessment

... in the jellyfish genome. Can scientists, and indeed science students, insert this gene into other organisms? Today you will perform a transformation using a paper model. What is a transformation? Bacteria have an extra piece of DNA that is much smaller than the rest of their genome, called a plasmid ...
DNA, Protein Synth, Mutations
DNA, Protein Synth, Mutations

... 1.2 Protein Synthesis Part I- The Role of Proteins Why are proteins so important anyways? • Humans share most of the same protein families with WORMS, flies, and plants • Hair grows by forming new cells at the base of the root. As they move upward through the skin they are cut off from their nutrie ...
Klinisches Fehler- und Risikomanagement
Klinisches Fehler- und Risikomanagement

... in vitro DHA (Docosahexaenoic acid) PPARβ mRNA ↓ → growth of breast cancer cells ↓ Loads of miRNAs → T-Zell-Regulation, B-Zell-Differenzierung miRNA transferring inbformation from mother to child after birth[17] ...
Mutated
Mutated

... (mutation in a gene linked with cancer) ...
Nucleic Acid Chemistry
Nucleic Acid Chemistry

... • Opposite direction of replication • Discontinuous – Okazaki fragments ...
deoxyribonucleic acid
deoxyribonucleic acid

DNATeachPrep
DNATeachPrep

... know about DNA structure, function and replication (without looking at their earlier storyboard or the Student Handout). After this, students should have prompt feedback so they can improve the accuracy and completeness of their storyboards; you can accomplish this in a class discussion where studen ...
KS4 Chromosomes, Genes and DNA
KS4 Chromosomes, Genes and DNA

... There are four types of bases. They have complicated names so it is easier to use their initials instead. ...
Molecular taxonomy,use of modern methods in the identification of a
Molecular taxonomy,use of modern methods in the identification of a

... which means law of arrangements ( taxis- arrangement or order; nomos- law). It is the science of biological classification. It consists of three separate but interrelated parts i.e. classification, in which we arrange organisms into groups or taxa based on their mutual similarity or evolutionary rel ...
Name  __________________________________ Period _________ Ms Foglia • AP Biology Date ______________________
Name __________________________________ Period _________ Ms Foglia • AP Biology Date ______________________

... These are needed to transcribe the gene properly when it is read. In addition, the HindIII & EcoR1 restriction enzyme cutting sites (sequences of bases) are marked in bold on the Jellyfish Glo gene DNA. The two restriction enzymes and their respective restriction sites are listed below. These enzyme ...
Cloning a Paper Plasmid
Cloning a Paper Plasmid

... These are needed to transcribe the gene properly when it is read. In addition, the HindIII & EcoR1 restriction enzyme cutting sites (sequences of bases) are marked in bold on the Jellyfish Glo gene DNA. The two restriction enzymes and their respective restriction sites are listed below. These enzyme ...
Chromosome structure & Gene Expression
Chromosome structure & Gene Expression

... nucleosomes and are accessible to enzymes. 2. Telomeres ensure that chromosomes do not lose their termini at each round of replication: • DNA polymerase is unable to fill in an RNA primer’s length of nucleotides at the 5’ end of a new strand at chromosome tips. • This results in shortening the ends ...
Document
Document

... 2) Two exposed strands of DNA are base paired to create two antiparallel strands of RNA. 3) Messenger DNA molecules are build from complementary base pairs after the helicase unwinds the DNA and DNA polymerase attaches nucleotides to form two new messenger DNA strands. 4) DNA is unwound by topoisome ...
Chapter 4: DNA, Genes, and Protein Synthesis
Chapter 4: DNA, Genes, and Protein Synthesis

... In 1869, a chemist by the name of Friedrich Miescher found a substance in the cell nucleus that he called "nuclein." This substance became known as deoxyribonucleic acid, or DNA. In the 1950s, several researchers were attempting to discover the structure of DNA and exactly how it or some other molec ...
set 3
set 3

... may be several possible choices, in which case you must supply ALL possibilities. You must also fill in the boxes on the left with the appropriate designations of strand polarity (5’, 3’, NH2, COOH). DO NOT assume that any rows are given according to a standard left-right convention for writing pola ...
Exam3fall2005ch9-12.doc
Exam3fall2005ch9-12.doc

... 8) Since DNA replication is __________________, the lagging strands contains the Okazaki fragments that will be joined by ______________. a) Semiconservative, Polymerase b) Discontinuous, ligase c) Slow, accelerase d) Spontaneous, SSBP e) Complementary, helicase 9) The Central Dogma of Molecular Bio ...
Chapter 14
Chapter 14

... 1. usually inherit only one X chromosome (karyotype 45,X). ...
Exam IV 1710_1711 F'01.doc
Exam IV 1710_1711 F'01.doc

... The ribozymes and the associated proteins which function to help splice out the intervening sequences from primary RNA transcripts (newly made RNAs) in eukaryotes are called: a. ...
Local DNA stretching mimics the distortion caused by - ENS-phys
Local DNA stretching mimics the distortion caused by - ENS-phys

... show that the structure induced by this interaction is conserved during the fixation of the transcription factors, TFIIA and TFIIB, which bind to the TBPyTATA complex. The mode of binding of TBP differs from that of most other proteins that interact with DNA. Unlike the majority of DNA-binding prote ...
Section F
Section F

Anatomy and Physiology BIO 137
Anatomy and Physiology BIO 137

... PCR and Forensic Science • Forensic science is the application of a broad spectrum of sciences to answer questions of interest to the legal system. This may be in relation to a crime or to a civil action. • It is often of interest in forensic science to identify individuals genetically. In these ca ...
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Nucleic acid double helix



In molecular biology, the term double helix refers to the structure formed by double-stranded molecules of nucleic acids such as DNA. The double helical structure of a nucleic acid complex arises as a consequence of its secondary structure, and is a fundamental component in determining its tertiary structure. The term entered popular culture with the publication in 1968 of The Double Helix: A Personal Account of the Discovery of the Structure of DNA, by James Watson.The DNA double helix polymer of nucleic acids, held together by nucleotides which base pair together. In B-DNA, the most common double helical structure, the double helix is right-handed with about 10–10.5 base pairs per turn. This translates into about 20-21 nucleotides per turn. The double helix structure of DNA contains a major groove and minor groove. In B-DNA the major groove is wider than the minor groove. Given the difference in widths of the major groove and minor groove, many proteins which bind to B-DNA do so through the wider major groove.
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