High dose intravenous immunoglobulin treatment: Mechanisms of
... immune system is not as widely accepted, although the efficacy of IVIg treatment has been demonstrated in several autoimmune diseases.1-4 IVIg preparations are fractionated from a plasma pool of healthy donors and contain both immune antibodies and physiologic autoantibodies. As immune antibodies refl ...
... immune system is not as widely accepted, although the efficacy of IVIg treatment has been demonstrated in several autoimmune diseases.1-4 IVIg preparations are fractionated from a plasma pool of healthy donors and contain both immune antibodies and physiologic autoantibodies. As immune antibodies refl ...
References - Specialist Pharmacy Service
... at the right dose for an appropriate duration of time, or the presence of intolerable side effects. When switching between antidepressants there is the potential for interaction between the two agents and/or for the patient to experience drug discontinuation symptoms from withdrawal of the first dru ...
... at the right dose for an appropriate duration of time, or the presence of intolerable side effects. When switching between antidepressants there is the potential for interaction between the two agents and/or for the patient to experience drug discontinuation symptoms from withdrawal of the first dru ...
Chapter-3 Drug and excipients profile
... restrictions on the length of treatment for Zollinger-Ellison syndrome or other disorders accompanied by pathological gastric acid hypersecretion; treatment should be maintained for as long as it is clinically required. Eradication of Helicobacter pylori: Pantoprazole at dosages ranging from 40 to 8 ...
... restrictions on the length of treatment for Zollinger-Ellison syndrome or other disorders accompanied by pathological gastric acid hypersecretion; treatment should be maintained for as long as it is clinically required. Eradication of Helicobacter pylori: Pantoprazole at dosages ranging from 40 to 8 ...
PRODUCT MONOGRAPH Pr INDERAL®-LA (Propranolol
... INDERAL-LA acts selectively without completely abolishing the inotropic action of digitalis on the heart muscle (i.e. that of supporting the strength of myocardial contractions). In patients already receiving digitalis, the positive inotropic action of digitalis may be reduced by propranolol hydroch ...
... INDERAL-LA acts selectively without completely abolishing the inotropic action of digitalis on the heart muscle (i.e. that of supporting the strength of myocardial contractions). In patients already receiving digitalis, the positive inotropic action of digitalis may be reduced by propranolol hydroch ...
Monitored Anesthesia Care with Dexmedetomidine: A
... that can be used safely during MAC in both healthy and high-risk patients, with limited adverse effects. Dexmedetomidine (Precedex威, Hospira, Lake Forest, IL) is a centrally acting ␣-2 receptor agonist that can be titrated to the desired level of sedation without significant respiratory depression. ...
... that can be used safely during MAC in both healthy and high-risk patients, with limited adverse effects. Dexmedetomidine (Precedex威, Hospira, Lake Forest, IL) is a centrally acting ␣-2 receptor agonist that can be titrated to the desired level of sedation without significant respiratory depression. ...
Comparison of the effects of cimetidine and hyoscine-n
... that most of the studies involving Cimetidine claimed that the drug has no effect on gastrointestinal tract (GIT) motility and hence its effect on the absorption of other orally co-administered drugs cannot be attributed to a possible effect on gastric motility [5,6,7]. However, Garba et al [8] had ...
... that most of the studies involving Cimetidine claimed that the drug has no effect on gastrointestinal tract (GIT) motility and hence its effect on the absorption of other orally co-administered drugs cannot be attributed to a possible effect on gastric motility [5,6,7]. However, Garba et al [8] had ...
Reviews Essential Tremor - Tremor and Other Hyperkinetic
... (CNS), based on weight-loading studies, lack of immediate effect with arteriole infusion, and reduced cerebellar activity on PET following ingestion.14–16 Ethanol may additionally improve tremor via peripheral mechanisms as it has been shown to reduce enhanced physiologic tremor.14 It is not known w ...
... (CNS), based on weight-loading studies, lack of immediate effect with arteriole infusion, and reduced cerebellar activity on PET following ingestion.14–16 Ethanol may additionally improve tremor via peripheral mechanisms as it has been shown to reduce enhanced physiologic tremor.14 It is not known w ...
Activated Charcoal - Paramedic Advantage
... Adult: 2.5 mg in 3cc NS (0.5% solution) over 5-15 minutes utilizing 6-8 LPM of oxygen, prn (for hyperkalemia: 10-20mg over 15 minutes) Pediatric: 0.1 – 0.3 mg/kg of a 0.5% solution, prn LA Co: Respiratory - 5 mg in 3 cc of NS with hand held nebulizer/mask over 5-15 minutes, repeat as needed. Crush S ...
... Adult: 2.5 mg in 3cc NS (0.5% solution) over 5-15 minutes utilizing 6-8 LPM of oxygen, prn (for hyperkalemia: 10-20mg over 15 minutes) Pediatric: 0.1 – 0.3 mg/kg of a 0.5% solution, prn LA Co: Respiratory - 5 mg in 3 cc of NS with hand held nebulizer/mask over 5-15 minutes, repeat as needed. Crush S ...
Guidline for managment of Hyperyension in Primary care
... Bahrain showed that 16.3% (289 out of 1769) of adults aged 20 to 64 years were known cases of hypertension, and another 26.4% (467 / 1769) had above normal average systolic or diastolic blood pressure. ...
... Bahrain showed that 16.3% (289 out of 1769) of adults aged 20 to 64 years were known cases of hypertension, and another 26.4% (467 / 1769) had above normal average systolic or diastolic blood pressure. ...
(HMG-CoA) REDUCTASE INHIBITORS ON THE CYP3A4
... values of itraconazole using human liver microsomes and applied them to a pharmacokinetic model (Ito et al., 1998), together with pharmacokinetic parameters for itraconazole. As a result, we have found that the predicted increase in plasma levels of simvastatin by concomitant administration of itrac ...
... values of itraconazole using human liver microsomes and applied them to a pharmacokinetic model (Ito et al., 1998), together with pharmacokinetic parameters for itraconazole. As a result, we have found that the predicted increase in plasma levels of simvastatin by concomitant administration of itrac ...
Product Monograph - Ask Novartis Pharma
... time of its occurrence (Tmax of 1 hour) are unaffected. The onset of effect occurs after the first administration and is maintained during long-term treatment. In a dose-response study in patients with Parkinson’s disease, the maximal effect was obtained with a single dose of 200 mg entacapone. Dose ...
... time of its occurrence (Tmax of 1 hour) are unaffected. The onset of effect occurs after the first administration and is maintained during long-term treatment. In a dose-response study in patients with Parkinson’s disease, the maximal effect was obtained with a single dose of 200 mg entacapone. Dose ...
Enhancement of Taste Masking by A newly
... palatability and mask taste, effectiveness and bioavailability. The Flavoring agent (vanillin) was employed to mask taste besides having a good odor. Wet granulation is very good for production of effervescent tablet rather than dry compression method Tables 5 and 6).Guar gum in a 1% w/w concentrati ...
... palatability and mask taste, effectiveness and bioavailability. The Flavoring agent (vanillin) was employed to mask taste besides having a good odor. Wet granulation is very good for production of effervescent tablet rather than dry compression method Tables 5 and 6).Guar gum in a 1% w/w concentrati ...
Epinephrine
... adrenal glands as a hormone into the blood. It is also a neurotransmitter in the nervous system where it is released from noradrenergic neurons during synaptic transmission. Norepinephrine can be methylated by phenylethanolamine N-methyltransferase to epinephrine [10]. Excretion: 60-70% is excreted ...
... adrenal glands as a hormone into the blood. It is also a neurotransmitter in the nervous system where it is released from noradrenergic neurons during synaptic transmission. Norepinephrine can be methylated by phenylethanolamine N-methyltransferase to epinephrine [10]. Excretion: 60-70% is excreted ...
Poonam et al - Galaxy of Pharmaceutical Innovations
... complex. The complexing agent is capable of masking the bitter taste of drug by either decreasing its oral solubility on ingestion or decreasing the amount of drug particles exposed to taste buds, thereby reducing the perception of bitter taste. This method is most suitable only for low dose drugs. ...
... complex. The complexing agent is capable of masking the bitter taste of drug by either decreasing its oral solubility on ingestion or decreasing the amount of drug particles exposed to taste buds, thereby reducing the perception of bitter taste. This method is most suitable only for low dose drugs. ...
Pipeline/Commercial Insight: Molecular Targeted Cancer
... stimulator that has reached the market and achieved success in the treatment of multiple myeloma, another product in this class, Genta’s Genasense, has suffered significant setbacks in its commercialization. As evidenced here, although Genasense has been at an advanced stage of development for sever ...
... stimulator that has reached the market and achieved success in the treatment of multiple myeloma, another product in this class, Genta’s Genasense, has suffered significant setbacks in its commercialization. As evidenced here, although Genasense has been at an advanced stage of development for sever ...
Nancy Caroline`s Emergency Care in the Streets, Seventh Edition
... Copyright © 2013 by Jones & Bartlett Learning, LLC, an Ascend Learning Company • www.jblearning.com ...
... Copyright © 2013 by Jones & Bartlett Learning, LLC, an Ascend Learning Company • www.jblearning.com ...
Bisoprolol Fumarate 1.25 mg, 2.5 mg, 5 mg and 10 mg Tablets
... medicines known as beta blockers. These medicines work by affecting the body’s response to some nerve impulses, especially in the heart. As a result, bisoprolol slows down heart rate and makes the heart more efficient at pumping blood around the body. Bisoprolol is used : ...
... medicines known as beta blockers. These medicines work by affecting the body’s response to some nerve impulses, especially in the heart. As a result, bisoprolol slows down heart rate and makes the heart more efficient at pumping blood around the body. Bisoprolol is used : ...
Sucroferric oxyhydroxide - Therapeutic Goods Administration
... While the iron oxide particle size is important in determining the phosphate binding, it is relatively difficult to directly measure. The sucrose/starch “wrapped” drug substance particle size is established and the process is controlled, but it does not correlate well with phosphate adsorption. Sucr ...
... While the iron oxide particle size is important in determining the phosphate binding, it is relatively difficult to directly measure. The sucrose/starch “wrapped” drug substance particle size is established and the process is controlled, but it does not correlate well with phosphate adsorption. Sucr ...
safety and pharmacokinetics of a preservative-free
... steroid formulation.12 The recent cases of sterile endophthalmitis using Kenalog7–10 may be related to the additives because pure TA has been shown to be safe in animal studies.17 Kenalog, the only commercially available TA formulation in the United States, is approved for intraarticular and intramu ...
... steroid formulation.12 The recent cases of sterile endophthalmitis using Kenalog7–10 may be related to the additives because pure TA has been shown to be safe in animal studies.17 Kenalog, the only commercially available TA formulation in the United States, is approved for intraarticular and intramu ...
Differential Cardiovascular and Renal Responses Produced by
... Oiso et al., 1988; Yamada et al., 1989; Brooks et al., 1991a,b, 1993). Despite evidence supporting a central action, the specific brain site(s) where -opioids act to affect the renal handling of water and electrolytes has not been established in vivo. Using compartmentalized rat hypothalamoneurohyp ...
... Oiso et al., 1988; Yamada et al., 1989; Brooks et al., 1991a,b, 1993). Despite evidence supporting a central action, the specific brain site(s) where -opioids act to affect the renal handling of water and electrolytes has not been established in vivo. Using compartmentalized rat hypothalamoneurohyp ...
Efficacy of Lidocaine Iontophoresis Using Either Alternating or Direct
... 4.1 Skin damage after iontophoresis application In this study, there were no signs of skin damage such as erythema or burns in the AC-IOP or DC-IOP group, to which electrical current was applied. Generally, DCIOP has side effects described above because of the hydrogen and hydroxide ions generated ...
... 4.1 Skin damage after iontophoresis application In this study, there were no signs of skin damage such as erythema or burns in the AC-IOP or DC-IOP group, to which electrical current was applied. Generally, DCIOP has side effects described above because of the hydrogen and hydroxide ions generated ...
Seizures - Morning Report
... ethosuximide are generally used as 1st line therapy for most seizure disorders and most new ones are used as add-on or alternative therapy. – Efficacy, convenience of dosing, and side effects are factors that influence the choice of initial medication. – Almost all of the commonly used drugs can cau ...
... ethosuximide are generally used as 1st line therapy for most seizure disorders and most new ones are used as add-on or alternative therapy. – Efficacy, convenience of dosing, and side effects are factors that influence the choice of initial medication. – Almost all of the commonly used drugs can cau ...
STABILITY INDICATING HPLC METHOD FOR SIMULTANEOUS DETERMINATION OF DROTAVERINE AND ACECLOFENAC Research Article
... Accuracy of the method was carried out by recovery studies using standard addition method at three different concentration levels. Summary of validation and system suitability test parameters are given in table 2. Repeatability of measurements of peak area was ca ...
... Accuracy of the method was carried out by recovery studies using standard addition method at three different concentration levels. Summary of validation and system suitability test parameters are given in table 2. Repeatability of measurements of peak area was ca ...