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8brain - lgh
8brain - lgh

... Consolidation of short-term memory into longterm memory. Requires activation of genes. growth of dendritic spines. ...
Experimental heart failure causes depression
Experimental heart failure causes depression

... reported in brain nuclei of rats with experimental CHF (Hu et al., 2001) and in humans (Almeida et al., 2012). However, the mechanisms and potential systemic consequences, as well as structural or molecular changes in the brain due to CHF are unknown. Moreover, no studies in mice were conducted so f ...
Neural effects of positive and negative incentives during marijuana
Neural effects of positive and negative incentives during marijuana

... non-drug (i.e., money) rewards in marijuana users. Using the monetary incentive delay (MID) task to determine reward processes for monetary rewards in marijuana users, Nestor et al. (2010) reported that greater VS response also underlies anticipation of a possible monetary gain. However, sensitivity ...
pdf
pdf

... It interconnects portions of the frontal, parietal, and temporal lobes. Its arching course over the corpus callosum resembles the palm of an open hand with fingertips wrapping beneath the rostrum of the corpus callosum. Superior Occipitofrontal Fasciculus: Whereas the cingulum wraps around the super ...
Cerebellar fastigial nucleus: from anatomic construction to
Cerebellar fastigial nucleus: from anatomic construction to

... and interneurons, with long axons projecting out of the cerebellar nuclei and short axons connecting only with neurons within the FN, respectively [1, 14]. Based on the transmitter phenotypes, glutamatergic, GABAergic as well as glycinergic neurons have been identified in the FN [1, 14, 15]. In addi ...
View PDF - MRC Brain Network Dynamics Unit
View PDF - MRC Brain Network Dynamics Unit

... transfers information to the BG through the striatum and subthalamic nucleus (STN), but may also indirectly influence the BG by the globus pallidus [GP; or external segment of globus pallidus in primates (GPe)] and thalamus. Processed information is transmitted out of the BG through the substantia n ...
ANS: c, p. 42, F, LO=2.1, (1)
ANS: c, p. 42, F, LO=2.1, (1)

... d) cerebellum 8. If you have a problem remembering things that happened a year ago, doctors might check for damage to the ___________ area of the brain. a) hippocampus b) hypothalamus c) fornix d) amygdala ...
Diversity of laminar connections linking periarcuate and
Diversity of laminar connections linking periarcuate and

... probes to visualize the distribution of CB or PV in lateral intraparietal areas along with fluorescent tracers (FE). Matched series of sections were incubated in primary antibody for either CB or PV (as described above). The tissue was then placed overnight in goat antimouse IgG conjugated with the fl ...
Prediction of Subjective Affective State From Brain Activations
Prediction of Subjective Affective State From Brain Activations

... Techniques have been developed to enable the information provided by populations of simultaneously recorded neurons to be analyzed (Aggelopoulos et al. 2005; Franco et al. 2004; Rolls et al. 1997a), and in this section, we extend these techniques to the analysis of functional imaging data. These tec ...
Program - Albion
Program - Albion

... stimulated by high level neural activity (the cfos promoter) to generate mice in which a genetic tag can  be introduced into neurons based their activity at a given point in time.  Using this approach we found  that neurons activated during learning were reactivated during recall of the memory and t ...
Feeling others` painful actions: The sensorimotor
Feeling others` painful actions: The sensorimotor

... which relevant somatosensory brain regions may support the action understanding task. First, they may simply be involved in coding sensory-tactile qualities of the objects. If this is the case, some regions should show a preference for actions involving noxious objects, irrespective of whether they ...
Hypothalamic regulation of sleep and circadian rhythms
Hypothalamic regulation of sleep and circadian rhythms

... within a remarkably short period of time, the molecular basis of this mysterious illness was identified. Interestingly, few people with narcolepsy have mutations in either the orexin ligand or receptor genes49,51. In most narcoleptics, the disease begins in the second or third decade of life, and th ...
Kandel ch. 43 + Two review papers
Kandel ch. 43 + Two review papers

... THE BASAL GANGLIA CONSIST of four nuclei, portions of which play a major role in normal voluntary movement. Unlike most other components of the motor system, however, they do not have direct input or output connections with the spinal cord. These nuclei receive their primary input from the cerebral ...
Viewpoint Synaptic Connectivity and Neuronal Morphology: Two
Viewpoint Synaptic Connectivity and Neuronal Morphology: Two

... scaling estimate. In such an estimate, numerical coefficients of order one are ignored and the results apply when the number of neurons is large. The average length of each axon scales with the linear dimension of the network, R, e.g., with the width or height of a cubic volume. Each neuron has to s ...
Towards the utilization of EEG as a brain imaging tool
Towards the utilization of EEG as a brain imaging tool

... field outside the head and infers the sources and the temporal dynamics of these sources in the brain (Salmelin and Baillet, 2009; Williamson et al., 1991). It has been recognized for a long time that the EEG can be analyzed in the same way as the MEG; namely using topographic maps and spatial patter ...
Apparent Atypical Callosal Dysgenesis
Apparent Atypical Callosal Dysgenesis

... callosum in that it was in direct contact with each hippocampus, and the posterior pillars of the fornix came in contact with its dorsal and not its ventral surface. Kautzky [1 OJ considered a similar structure in a similarly malformed brain to be a true splenium and proposed that the anomalous brai ...
What can mice tell us about how vision works?
What can mice tell us about how vision works?

... how the 22 RGC subtypes found in the mouse correspond to the 20 subtypes in the primate. The recent identification of RGC subtype-specific genes and immunohistochemical markers in the mouse [31–37] will allow this question to be further addressed in primates, including humans. Indeed, studies of mou ...
Reward-Related Responses in the Human Striatum
Reward-Related Responses in the Human Striatum

... synaptic input from cortical and subcortical afferents, such as motor cortical input and dopaminergic projections from substantia nigra (but also other midbrain nuclei, such as the ventral tegmental area2,4,5,7–9 ). The striatum can be further subdivided into dorsal and ventral components. The dorsa ...
Physiological origins and functional correlates of EEG rhythmic
Physiological origins and functional correlates of EEG rhythmic

... major facts. First, this rhythmic activity originated in the somatosensory relay nuclei of the thalamus, collectively known as the Ventrobasal (VB) nuclei (Howe & Sterman, 1972). This finding was in agreement with a earlier body of evidence from anesthetized preparations, summarized in the popular t ...
Domain-general mechanisms of complex working memory span
Domain-general mechanisms of complex working memory span

... of CWMS have used somewhat varied measures of verbal CWMS (i.e., reading span, listening span, and operation span). Another problem is that the key fMRI contrasts have differed considerably across studies. For example, one approach (which we favor) is to contrast a CWMS condition (combined storage a ...
Neural Effects of Positive and Negative Incentives during
Neural Effects of Positive and Negative Incentives during

... non-drug (i.e., money) rewards in marijuana users. Using the monetary incentive delay (MID) task to determine reward processes for monetary rewards in marijuana users, Nestor et al. (2010) reported that greater VS response also underlies anticipation of a possible monetary gain. However, sensitivity ...
Receptores Monoaminérgicos en Corteza Prefrontal: Mecanismo de Acción de Fármacos Antipsicóticos
Receptores Monoaminérgicos en Corteza Prefrontal: Mecanismo de Acción de Fármacos Antipsicóticos

... NMDA receptor (NMDA-R) antagonists are extensively used as schizophrenia models due to their ability to evoke positive and negative symptoms as well as cognitive deficits similar to those of the illness. Cognitive deficits in schizophrenia are associated with prefrontal cortex (PFC) abnormalities. T ...
Possible Links among Mirror Neurons and Genes
Possible Links among Mirror Neurons and Genes

... A relation between autism and certain factors has been argued. Due to the development of the brain imaging study, neuroscience has been paid much attention. Moreover, the recent autism study is mainly based on genetics. The relations between autism and mirror neurons have been pointed out, but recen ...
Volatile Solvents as Drugs of Abuse: Focus on the Cortico
Volatile Solvents as Drugs of Abuse: Focus on the Cortico

Olfactory pathway
Olfactory pathway

... the temporal lobe (uncus). Then to olfactory association cortex (anterior part of parahippocampal gyrus or entorinal area). The primary olfactory area and olfactory association cortex are referred to as the pyriform cortex. It is responsible for the appreciation of olfactory stimuli. ...
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Aging brain

Age is a major risk factor for most common neurodegenerative diseases, including Mild cognitive impairment, Alzheimer's disease, cerebrovascular disease, Parkinson's disease and Lou Gehrig's disease. While much research has focused on diseases of aging, there are few informative studies on the molecular biology of the aging brain (usually spelled ageing brain in British English) in the absence of neurodegenerative disease or the neuropsychological profile of healthy older adults. However, research does suggest that the aging process is associated with several structural, chemical, and functional changes in the brain as well as a host of neurocognitive changes. Recent reports in model organisms suggest that as organisms age, there are distinct changes in the expression of genes at the single neuron level. This page is devoted to reviewing the changes associated with healthy aging.
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