Overview of relaxin
... connective tissue. Perhaps its most principle role is to regulate the synthesis and maintainence of collagen, our primary connective tissue protein. Every part of our body and virtually every body function is thus affected or potentially influenced by relaxin. Muscle/tendon and ligament integrity, n ...
... connective tissue. Perhaps its most principle role is to regulate the synthesis and maintainence of collagen, our primary connective tissue protein. Every part of our body and virtually every body function is thus affected or potentially influenced by relaxin. Muscle/tendon and ligament integrity, n ...
Emerging role of Nrf2 - Discovery
... upon challenge with agents causing oxidative stress. Moreover, cells deficient in Nrf2 are much more sensitive to the toxicity of oxidants of various types and cannot be protected by Nrf2 inducers, which, under the same conditions, provide efficient and long-lasting protection to WT cells [29,36,37]. ...
... upon challenge with agents causing oxidative stress. Moreover, cells deficient in Nrf2 are much more sensitive to the toxicity of oxidants of various types and cannot be protected by Nrf2 inducers, which, under the same conditions, provide efficient and long-lasting protection to WT cells [29,36,37]. ...
Wax ester fermentation and fatty acid biosynthesis in the facultatively
... level was very high. The advent of oxygen took place during the time from 2.5 to ca 0.6 Ga (Canfield 1998; Anbar and Knoll 2001; Canfield et al. 2007) and the eukaryotes must have arisen and diversified by that time at very low oxygen tension and high sulfide concentration as anaerobic organisms (Ma ...
... level was very high. The advent of oxygen took place during the time from 2.5 to ca 0.6 Ga (Canfield 1998; Anbar and Knoll 2001; Canfield et al. 2007) and the eukaryotes must have arisen and diversified by that time at very low oxygen tension and high sulfide concentration as anaerobic organisms (Ma ...
The enzymes of biotin dependent CO2 metabolism: What structures
... which contains a three-stranded anti-parallel b-sheet covered on one side by two a-helices. The C-domain is the most complicated of the three regions. It contains an eight-stranded antiparallel b-sheet, a threestranded anti-parallel b-sheet, and seven a-helices. The A- and B-domains are connected by ...
... which contains a three-stranded anti-parallel b-sheet covered on one side by two a-helices. The C-domain is the most complicated of the three regions. It contains an eight-stranded antiparallel b-sheet, a threestranded anti-parallel b-sheet, and seven a-helices. The A- and B-domains are connected by ...
Exploring the directionality of Escherichia coli formate
... reduction in vitro and in situ (Krasna 1984; Sawers et al. 1985; Maeda et al. 2007). The isolated FDH-H enzyme is bidirectional in electrochemistry experiments (Bassegoda et al. 2014). Moreover, very early work with intact wild- type E. coli cells showed that formic acid could be produced when the ...
... reduction in vitro and in situ (Krasna 1984; Sawers et al. 1985; Maeda et al. 2007). The isolated FDH-H enzyme is bidirectional in electrochemistry experiments (Bassegoda et al. 2014). Moreover, very early work with intact wild- type E. coli cells showed that formic acid could be produced when the ...
Global transcriptional control by glucose and
... B. anthracis are attenuated on virulence in animal models of infection (24,28). The coordinate CcpA-dependent regulation of virulence and carbon utilization genes might be critical for fitness when pathogens compete with other microbes for niche colonization (23). Recently, we have demonstrated that ...
... B. anthracis are attenuated on virulence in animal models of infection (24,28). The coordinate CcpA-dependent regulation of virulence and carbon utilization genes might be critical for fitness when pathogens compete with other microbes for niche colonization (23). Recently, we have demonstrated that ...
IOSR Journal of Environmental Science, Toxicology and Food Technology (IOSR-JESTFT)
... the help of a combination of HA-33, HA-17 & HA-55 proteins (HA-55 is derived from HA-70 by a proteolytic process, another subunit is HA-22-23) as these combination of protein is necessary for hemagglutination activity3. ...
... the help of a combination of HA-33, HA-17 & HA-55 proteins (HA-55 is derived from HA-70 by a proteolytic process, another subunit is HA-22-23) as these combination of protein is necessary for hemagglutination activity3. ...
cerevisiae - Oxford Academic
... also reported the insertion of tyrosine, lysine and tryptophan at UAG stop codons in yeast Ste6p (28). Most of the available data concerning the nature of the amino acids inserted by readthrough were obtained from in vitro studies on plant tRNAs and viral mRNAs. Very few in vivo data are available, ...
... also reported the insertion of tyrosine, lysine and tryptophan at UAG stop codons in yeast Ste6p (28). Most of the available data concerning the nature of the amino acids inserted by readthrough were obtained from in vitro studies on plant tRNAs and viral mRNAs. Very few in vivo data are available, ...
A study on the efficient production of lactic acid with metabolically
... reduction of resources is gradually becoming serious. An important goal in the 21st century is to form a sustainable society that is in harmony with the earth. To achieve such a new society, it is necessary to create an original technology that harmonizes the global environment with maintenance of t ...
... reduction of resources is gradually becoming serious. An important goal in the 21st century is to form a sustainable society that is in harmony with the earth. To achieve such a new society, it is necessary to create an original technology that harmonizes the global environment with maintenance of t ...
Neurotransmitter Transporters in the Central Nervous System
... cellular loops and the presence of an additional N-glycosylation site in the fourth extracellular loop (Fig. 2). The four transporter-like proteins have significant homology (;20 –30%) with the “classical” members such as the DA, serotonin, GABA, or glycine transporters. However, the overall percent ...
... cellular loops and the presence of an additional N-glycosylation site in the fourth extracellular loop (Fig. 2). The four transporter-like proteins have significant homology (;20 –30%) with the “classical” members such as the DA, serotonin, GABA, or glycine transporters. However, the overall percent ...
DISCOVERY OF ENZYMES RESPONSIBLE FOR AN ALTERNATE
... Archaea are a distinct evolutionary domain of microorganisms that contain isoprenoids in ether linkages to glycerol rather than the ester linked fatty acids that characterize membranes of bacteria or eukaryotes. Radiolabeling experiments with acetate and mevalonate strongly implicate the mevalonate ...
... Archaea are a distinct evolutionary domain of microorganisms that contain isoprenoids in ether linkages to glycerol rather than the ester linked fatty acids that characterize membranes of bacteria or eukaryotes. Radiolabeling experiments with acetate and mevalonate strongly implicate the mevalonate ...
Gene Section GAST (gastrin) Atlas of Genetics and Cytogenetics
... a calcium-dependent casein-like kinase. Although Osulfation is thought to occur primarily in the transGolgi network, a recent study provides evidence suggesting that it may continue through later compartments of the regulated secretory pathway. ...
... a calcium-dependent casein-like kinase. Although Osulfation is thought to occur primarily in the transGolgi network, a recent study provides evidence suggesting that it may continue through later compartments of the regulated secretory pathway. ...
Ammonia, urea production and pH regulation
... control is transcriptionally effected by changes in enzyme concentrations. Substrate provision for the urea cycle depends on amino acid delivery, the activity of amino acid transport systems, and amino acid metabolizing enzymes, and these factors are therefore important determinants of urea synthesi ...
... control is transcriptionally effected by changes in enzyme concentrations. Substrate provision for the urea cycle depends on amino acid delivery, the activity of amino acid transport systems, and amino acid metabolizing enzymes, and these factors are therefore important determinants of urea synthesi ...
Vanillin formation from ferulic acid in Vanilla planifolia is catalysed
... which upon tissue damage is hydrolysed to form the active defense compound, vanillin. Production of vanillin from the orchids is laborious, slow and costly. Five hundred kilograms of vanilla pods yields only 1 kg of vanillin. Less than 1% of the global vanillin production originates from the vanilla ...
... which upon tissue damage is hydrolysed to form the active defense compound, vanillin. Production of vanillin from the orchids is laborious, slow and costly. Five hundred kilograms of vanilla pods yields only 1 kg of vanillin. Less than 1% of the global vanillin production originates from the vanilla ...
A Comparative Study - Carlos Ibanez Lab @ KI
... basal forebrain cholinergic neurons has been used to argue that in SDAT a continuous administration of NGF into the brain may prevent degeneration of basal forebrain cholinergic neurons. However, NGF is probably not causally linked to the degeneration of basal forebrain cholinergic neurons in SDAT b ...
... basal forebrain cholinergic neurons has been used to argue that in SDAT a continuous administration of NGF into the brain may prevent degeneration of basal forebrain cholinergic neurons. However, NGF is probably not causally linked to the degeneration of basal forebrain cholinergic neurons in SDAT b ...
Systems Biotechnology of Pseudomonas putida for the enhanced
... along with a systems biotechnology approach with the aim of enhancing the production of PHAs. First, it was shown that P. putida and related species are suitable as whole-cell biocatalyzers for the production of several value-added industrial compounds. To highlight differences among various nutrien ...
... along with a systems biotechnology approach with the aim of enhancing the production of PHAs. First, it was shown that P. putida and related species are suitable as whole-cell biocatalyzers for the production of several value-added industrial compounds. To highlight differences among various nutrien ...
The Vitamin K-dependent Carboxylase*
... wild type or mutant recombinant carboxylase produced through mammalian or insect over-expression systems (46-48). Thus far, the presence of stoichiometrically bound prosthetic groups on carboxylase has not been reported. The apparent monooxygenase chemistry of carboxylase and inhibition of the enzym ...
... wild type or mutant recombinant carboxylase produced through mammalian or insect over-expression systems (46-48). Thus far, the presence of stoichiometrically bound prosthetic groups on carboxylase has not been reported. The apparent monooxygenase chemistry of carboxylase and inhibition of the enzym ...
A1018 High oleic GM soybean AppR SD1 Safety Assess AMENDED
... Recently there has been interest in genetically modifying oilseed fatty acids, particularly via directed gene down-regulation strategies (see discussion in Durrett et al., 2008; Liu et al., 2002). The increased levels of oleic acid in soybean 305423 have been achieved through the introduction of a p ...
... Recently there has been interest in genetically modifying oilseed fatty acids, particularly via directed gene down-regulation strategies (see discussion in Durrett et al., 2008; Liu et al., 2002). The increased levels of oleic acid in soybean 305423 have been achieved through the introduction of a p ...
Glutamate Dehydrogenases: Enzymology, Physiological
... there are three basic types of GDH: those that are cofactor specific for NAD (EC 1.4.1.2), those that are specific for NADP (EC 1.4.1.4) and those that can use either cofactor (EC 1.4.1.3) (dual coenzyme-specific GDHs). Lower eukaryotes and prokaryotes usually have GDHs that only function with one c ...
... there are three basic types of GDH: those that are cofactor specific for NAD (EC 1.4.1.2), those that are specific for NADP (EC 1.4.1.4) and those that can use either cofactor (EC 1.4.1.3) (dual coenzyme-specific GDHs). Lower eukaryotes and prokaryotes usually have GDHs that only function with one c ...
Pyruvate : NADP+ Oxidoreductase from the Mitochondrion of
... the earliest eukaryotic cells (Martin and Müller 1998). In principle, three alternative explanations could currently account for the distribution of PFO among eukaryotes and its evident correlation with the amitochondriate phenotype. The first possible explanation is that the host of mitochondrial ...
... the earliest eukaryotic cells (Martin and Müller 1998). In principle, three alternative explanations could currently account for the distribution of PFO among eukaryotes and its evident correlation with the amitochondriate phenotype. The first possible explanation is that the host of mitochondrial ...
- Wiley Online Library
... Systems analysis of biological networks in skeletal muscle function Lucas R. Smith,1 Gretchen Meyer1 and Richard L. Lieber2,3∗ Skeletal muscle function depends on the efficient coordination among subcellular systems. These systems are composed of proteins encoded by a subset of genes, all of which a ...
... Systems analysis of biological networks in skeletal muscle function Lucas R. Smith,1 Gretchen Meyer1 and Richard L. Lieber2,3∗ Skeletal muscle function depends on the efficient coordination among subcellular systems. These systems are composed of proteins encoded by a subset of genes, all of which a ...
Functional characterization of rare FOXP2 variants in
... Background: Heterozygous disruption of FOXP2 causes a rare form of speech and language impairment. Screens of the FOXP2 sequence in individuals with speech/language-related disorders have identified several rare protein-altering variants, but their phenotypic relevance is often unclear. FOXP2 encode ...
... Background: Heterozygous disruption of FOXP2 causes a rare form of speech and language impairment. Screens of the FOXP2 sequence in individuals with speech/language-related disorders have identified several rare protein-altering variants, but their phenotypic relevance is often unclear. FOXP2 encode ...
Purification of Arrestin from Bovine Retinas
... species. Arrestin contains a relatively high proportion of nonpolar amino acids (55%) that are assembled in a /3-sheet conformation (7, 8). However, very little is known about the biochemical/biophysical and structural properties of the protein. Arrestin is also of interest because of its ability to ...
... species. Arrestin contains a relatively high proportion of nonpolar amino acids (55%) that are assembled in a /3-sheet conformation (7, 8). However, very little is known about the biochemical/biophysical and structural properties of the protein. Arrestin is also of interest because of its ability to ...
Identification and characterization of novel interaction
... In Gram-positiven Bakterien mit niedrigem GC-Gehalt, wie Bacillus subtilis, wird KohlenstoffKatabolitenregulation überwiegend vom Katabolit Kontroll Protein A (CcpA), einem globalen Transkriptionsregulator, vermittelt. CcpA reprimiert oder aktiviert die Expression von hunderten von ...
... In Gram-positiven Bakterien mit niedrigem GC-Gehalt, wie Bacillus subtilis, wird KohlenstoffKatabolitenregulation überwiegend vom Katabolit Kontroll Protein A (CcpA), einem globalen Transkriptionsregulator, vermittelt. CcpA reprimiert oder aktiviert die Expression von hunderten von ...
The shikimate pathway in apicomplexan parasites: Implications for
... Whereas the fungal DHQase of the quinate pathway is encoded in a cluster of eight genes that is transcriptionally regulated in response to the presence of quinate, the respective enzyme of the shikimate pathway is part of the ...
... Whereas the fungal DHQase of the quinate pathway is encoded in a cluster of eight genes that is transcriptionally regulated in response to the presence of quinate, the respective enzyme of the shikimate pathway is part of the ...