Chlamydia Exploit the Mammalian Tryptophan-Depletion
... forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. ...
... forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. ...
RuBisCO in Non-Photosynthetic Alga Euglena longa: Divergent
... II RuBisCO). In these lineages, the Rbc gene was acquired from a bacterium by horizontal gene transfer [3]. In all other cases, the large subunit, possessing the catalytic activity of the holoenzyme, is always encoded in the plastid genome by the rbcL gene and synthesized on the plastid ribosomes in ...
... II RuBisCO). In these lineages, the Rbc gene was acquired from a bacterium by horizontal gene transfer [3]. In all other cases, the large subunit, possessing the catalytic activity of the holoenzyme, is always encoded in the plastid genome by the rbcL gene and synthesized on the plastid ribosomes in ...
Metabolic processes of Methanococcus maripaludis and potential
... The structures and functions of the cofactors and coenzymes involved in methanogenesis are listed in Table 2. The first step in methanogenesis is the reduction of CO2. It involves the simultaneous oxidation of low-potential reduced ferredoxins and capture of CO2 by methanofuran (MFR) to form formyl ...
... The structures and functions of the cofactors and coenzymes involved in methanogenesis are listed in Table 2. The first step in methanogenesis is the reduction of CO2. It involves the simultaneous oxidation of low-potential reduced ferredoxins and capture of CO2 by methanofuran (MFR) to form formyl ...
Relationship between Human Adipose Tissue Agouti and - Zen-Bio
... However, it is not known at present which factor(s) may modulate adipocyte agouti expression and how it is regulated. Further, because agouti is a paracrine/autocrine factor that does not enter the general circulation (Wolff 1963) and because it has been shown to regulate FAS expression and activity ...
... However, it is not known at present which factor(s) may modulate adipocyte agouti expression and how it is regulated. Further, because agouti is a paracrine/autocrine factor that does not enter the general circulation (Wolff 1963) and because it has been shown to regulate FAS expression and activity ...
Biochemical and Cellular Investigation of Vitreoscilla Hemoglobin
... spectra of wild-type VHb and P54R variants were nearly identical, and their untreated proteins were likely to be in a ferric state, with Soret peaks positioned at 406 and 408 nm, respectively. Y29H and Y29H/P54R variants revealed unusual absorption properties in which the Soret maxima were shifted t ...
... spectra of wild-type VHb and P54R variants were nearly identical, and their untreated proteins were likely to be in a ferric state, with Soret peaks positioned at 406 and 408 nm, respectively. Y29H and Y29H/P54R variants revealed unusual absorption properties in which the Soret maxima were shifted t ...
Investigating the link between tRNA and mRNA - EMBL-EBI
... overall efficiency for high efficiency in translating the most important subset of genes. To investigate this, I examine the link between mrna expression and trna abundance in a variety of biological conditions across several mammalian species, establishing that changes in the pool of trnas are not ...
... overall efficiency for high efficiency in translating the most important subset of genes. To investigate this, I examine the link between mrna expression and trna abundance in a variety of biological conditions across several mammalian species, establishing that changes in the pool of trnas are not ...
Simultaneous Alignment and Folding of Protein Sequences
... structure. Moreover, for proteins, there is no clear chemical basis for compensatory mutations [11], the energy models that define β-strand pairings are more complex, and the larger residue alphabet vastly increases the complexity of the problem. This class of problems is also different than any tha ...
... structure. Moreover, for proteins, there is no clear chemical basis for compensatory mutations [11], the energy models that define β-strand pairings are more complex, and the larger residue alphabet vastly increases the complexity of the problem. This class of problems is also different than any tha ...
Resistance to Antibiotics Mediated by Target Alterations
... of PBP 2 with a decreased affinity, for penicillin, but there is no evidence that they possess altered forms of PBP I (17). Analysis of the PBP 2 genes of penicillin-susceptible and penicillin-resistant gonococci and meningococci provided the first evidence that low-affinity PBPs arise by recombinat ...
... of PBP 2 with a decreased affinity, for penicillin, but there is no evidence that they possess altered forms of PBP I (17). Analysis of the PBP 2 genes of penicillin-susceptible and penicillin-resistant gonococci and meningococci provided the first evidence that low-affinity PBPs arise by recombinat ...
Towards the Molecular Basis of Sperm and Egg Interaction during
... ZP increases in thickness as the oocyte increases in diameter from F12 to F80 Ìm. At about the time of ovulation, synthesis and secretion of ZP glycoproteins cease. The ZP is a very porous extracellular matrix, permeable to large macromolecules (e.g., immunoglobulins) and small viruses [Gwatkin, 197 ...
... ZP increases in thickness as the oocyte increases in diameter from F12 to F80 Ìm. At about the time of ovulation, synthesis and secretion of ZP glycoproteins cease. The ZP is a very porous extracellular matrix, permeable to large macromolecules (e.g., immunoglobulins) and small viruses [Gwatkin, 197 ...
02 Cholesterol Metabolism2012-03-18 01:50617 KB
... Most important animal steroid Maintains membrane fluidity Insulating effect on nerve fibres Cholesterol is the parent molecule for – Bile acids and bile salts – Steroid hormones – Vitamin D3 ...
... Most important animal steroid Maintains membrane fluidity Insulating effect on nerve fibres Cholesterol is the parent molecule for – Bile acids and bile salts – Steroid hormones – Vitamin D3 ...
Channel-mediated lactic acid transport: a novel function for
... GlpF4 each facilitated the transmembrane diffusion of water, dihydroxyacetone and glycerol. As several lactic acid bacteria have GlpFs in their lactate racemization operon (GlpF1/F4 phylogenetic group), their ability to transport this organic acid was tested. Both GlpF1 and GlpF4 facilitated the dif ...
... GlpF4 each facilitated the transmembrane diffusion of water, dihydroxyacetone and glycerol. As several lactic acid bacteria have GlpFs in their lactate racemization operon (GlpF1/F4 phylogenetic group), their ability to transport this organic acid was tested. Both GlpF1 and GlpF4 facilitated the dif ...
Lipids as Tumoricidal Components of Human
... formation (26), suggesting that these fatty acids may share specific structural features required both for HAMLET formation and to engage targets involved in tumor cell death. In contrast, trans-poly/monounsaturated or fully saturated fatty acids failed to form a HAMLET-like complex under near ident ...
... formation (26), suggesting that these fatty acids may share specific structural features required both for HAMLET formation and to engage targets involved in tumor cell death. In contrast, trans-poly/monounsaturated or fully saturated fatty acids failed to form a HAMLET-like complex under near ident ...
Cloning and sequence analysis of cnaA gene encoding the catalytic
... remaining C-terminal region residues from 454 to 478 could be a part of the auto-inhibitory domain which is cleaved upon calmodulin binding and subsequent activation of cnaA [16]. It may also be observed that the carboxy-terminal domain shows lower sequence homology overall. In addition, the 5P and ...
... remaining C-terminal region residues from 454 to 478 could be a part of the auto-inhibitory domain which is cleaved upon calmodulin binding and subsequent activation of cnaA [16]. It may also be observed that the carboxy-terminal domain shows lower sequence homology overall. In addition, the 5P and ...
The Serratia gene cluster encoding biosynthesis of the red antibiotic
... Serratia 39006, Sma 274, and the undecylprodigiosin biosynthetic cluster (red cluster) from Str. coelicolor A3(2). Lines between the Str. coelicolor red and Serratia pig clusters trace the homologue genes relative positions in the two clusters. Regulatory genes of the red cluster are shown in black, ...
... Serratia 39006, Sma 274, and the undecylprodigiosin biosynthetic cluster (red cluster) from Str. coelicolor A3(2). Lines between the Str. coelicolor red and Serratia pig clusters trace the homologue genes relative positions in the two clusters. Regulatory genes of the red cluster are shown in black, ...
Patent constraints
... 1. An isolated nucleic acid molecule comprising a nucleotide sequence which (i) encodes a protein or polypeptide comprising an amino acid sequence of SEQ. ID. No. 3, SEQ. ID. No. 5, SEQ. ID. No. 7, SEQ. ID. No. 9, SEQ. ID. No. 11, SEQ. ID. No. 13, SEQ. ID. No. 15, SEQ. ID. No. 17, SEQ. ID. No. 20, S ...
... 1. An isolated nucleic acid molecule comprising a nucleotide sequence which (i) encodes a protein or polypeptide comprising an amino acid sequence of SEQ. ID. No. 3, SEQ. ID. No. 5, SEQ. ID. No. 7, SEQ. ID. No. 9, SEQ. ID. No. 11, SEQ. ID. No. 13, SEQ. ID. No. 15, SEQ. ID. No. 17, SEQ. ID. No. 20, S ...
In Vitro Characterization of Human Growth Hormone
... Growth hormone (GH) is a 22 kD, 191-aa, pituitary-derived peptide hormone that is essential for postnatal growth. GH signals via binding to GH receptor (GHR), which initiates intracellular signal transduction pathways. This leads to activation of target genes, most importantly the one encoding insul ...
... Growth hormone (GH) is a 22 kD, 191-aa, pituitary-derived peptide hormone that is essential for postnatal growth. GH signals via binding to GH receptor (GHR), which initiates intracellular signal transduction pathways. This leads to activation of target genes, most importantly the one encoding insul ...
Sequence and phylogenetic analysis of the gp200 protein of
... United States (AF252298 and CP000107), the gp200 open reading frame was 4,266 bp in length and encoded a protein of 1,421 amino acids. The complete gp200 coding sequences derived from 17 Taiwanese samples were identical or nearly identical to each other (99.9∼100% identities), even though the canine ...
... United States (AF252298 and CP000107), the gp200 open reading frame was 4,266 bp in length and encoded a protein of 1,421 amino acids. The complete gp200 coding sequences derived from 17 Taiwanese samples were identical or nearly identical to each other (99.9∼100% identities), even though the canine ...
MS#5_(Cueno and Laude).indd - Philippine Journal of Science
... (Banzon and Velasco 1982; Harries 1994) further suggesting ontogenetic gene expression which coincides with the hypothesis made by Villalobos et al. (2001). This would suggest a temporal pattern of gene regulation among coconut genes involved in fatty acid synthesis. The untranslated region (UTR) is ...
... (Banzon and Velasco 1982; Harries 1994) further suggesting ontogenetic gene expression which coincides with the hypothesis made by Villalobos et al. (2001). This would suggest a temporal pattern of gene regulation among coconut genes involved in fatty acid synthesis. The untranslated region (UTR) is ...
Nucleic acid vaccines against rickettsial diseases and methods of use
... This application is a continuation-in-part of Ser. No. 09/337,827, ?led Jun. 22, 1999 noW abandoned; Which is a divisional of Ser. No. 08/953,326, ?led Oct. 17, 1997, now US. Pat. No. 6,251,872; Which is a continuation-in-part of ...
... This application is a continuation-in-part of Ser. No. 09/337,827, ?led Jun. 22, 1999 noW abandoned; Which is a divisional of Ser. No. 08/953,326, ?led Oct. 17, 1997, now US. Pat. No. 6,251,872; Which is a continuation-in-part of ...
Desert hedgehog is a mammal-specific gene expressed during testicular and ovarian
... patched (PTCH) receptors and smoothened (SMO) protein [17]. Both proteins have orthologues in Drosophila that are also involved in hedgehog signal transduction and pattern formation. Initially, all three hedgehog protein functions were thought to be mediated through the PTCH1 receptor in mammals. Ho ...
... patched (PTCH) receptors and smoothened (SMO) protein [17]. Both proteins have orthologues in Drosophila that are also involved in hedgehog signal transduction and pattern formation. Initially, all three hedgehog protein functions were thought to be mediated through the PTCH1 receptor in mammals. Ho ...
Desert hedgehogis a mammal-specific gene expressed during
... patched (PTCH) receptors and smoothened (SMO) protein [17]. Both proteins have orthologues in Drosophila that are also involved in hedgehog signal transduction and pattern formation. Initially, all three hedgehog protein functions were thought to be mediated through the PTCH1 receptor in mammals. Ho ...
... patched (PTCH) receptors and smoothened (SMO) protein [17]. Both proteins have orthologues in Drosophila that are also involved in hedgehog signal transduction and pattern formation. Initially, all three hedgehog protein functions were thought to be mediated through the PTCH1 receptor in mammals. Ho ...
Glucose transporters (GLUT and SGLT)
... dietary glucose with fructose. The magnitude of this disorder, by the mutation of a single gene, would indicate that alternative lumenal glucose transport does not occur to any significant extent. The relevance of SGLT3 intestinal expression needs to be addressed and suggests that care should be tak ...
... dietary glucose with fructose. The magnitude of this disorder, by the mutation of a single gene, would indicate that alternative lumenal glucose transport does not occur to any significant extent. The relevance of SGLT3 intestinal expression needs to be addressed and suggests that care should be tak ...
AMINO ACID SEQUENCES AND EVOLUTIONARY RELATIONSHIPS
... common function, provide some of the most significant evidence supporting the theory of evolution. For example, the forelimbs of vertebrates often have different functions and outward appearances, yet the underlying similarity in the bone structure indicates a common origin. Although homologous stru ...
... common function, provide some of the most significant evidence supporting the theory of evolution. For example, the forelimbs of vertebrates often have different functions and outward appearances, yet the underlying similarity in the bone structure indicates a common origin. Although homologous stru ...
Identification of a Cis-Acting Element of ART1, a
... 2009). Recently, Nrat1 (Nramp Al transporter 1), belonging to Nramp (natural resistance-associated macrophage protein) family, was reported to be required for Al tolerance in rice (Xia et al., 2010). Nrat1 is localized at the plasma membranes of all root cells and functions as a transporter for upta ...
... 2009). Recently, Nrat1 (Nramp Al transporter 1), belonging to Nramp (natural resistance-associated macrophage protein) family, was reported to be required for Al tolerance in rice (Xia et al., 2010). Nrat1 is localized at the plasma membranes of all root cells and functions as a transporter for upta ...
PDF - Journal of Rare Disorders
... the control of nuclear DNA over mitochondrial DNA and mitochondrial biogenesis, researchers are looking into the nuclear DNA.19‐22 Mitochondrial disorders may also be the result of acquired mitochondrial dysfunc on due to drugs, infec ons and environmental factors.23 Mit ...
... the control of nuclear DNA over mitochondrial DNA and mitochondrial biogenesis, researchers are looking into the nuclear DNA.19‐22 Mitochondrial disorders may also be the result of acquired mitochondrial dysfunc on due to drugs, infec ons and environmental factors.23 Mit ...
Endogenous retrovirus
Endogenous retroviruses (ERVs) are endogenous viral elements in the genome that closely resemble and can be derived from retroviruses. They are abundant in the genomes of jawed vertebrates, and they comprise up to 5–8% of the human genome (lower estimates of ~1%). ERVs are a subclass of a type of gene called a transposon, which can be packaged and moved within the genome to serve a vital role in gene expression and in regulation. Researchers have suggested that retroviruses evolved from a type of transposable gene called a retrotransposon, which includes ERVs; these genes can mutate and instead of moving to another location in the genome they can become exogenous or pathogenic. This means that all ERVs may not have originated as an insertion by a retrovirus but that some may have been the source for the genetic information in the retroviruses they resemble.