The relevance of carbon dioxide metabolism in
... medium revealed that CO2 depletion resulted in bacterial arginine, aspartate and uracil auxotrophy. Moreover, CO2 depletion governed a significant change in cell morphology, and a high reduction in biomass production. A comparative proteomic analysis revealed that cells of S. thermophilus showed a d ...
... medium revealed that CO2 depletion resulted in bacterial arginine, aspartate and uracil auxotrophy. Moreover, CO2 depletion governed a significant change in cell morphology, and a high reduction in biomass production. A comparative proteomic analysis revealed that cells of S. thermophilus showed a d ...
Dot Plot - APBioNET
... Homology is inferred from Similarity If two sequences are similar, then they are known as homologous sequences. Usually, at least 30% identity over 400 bp for DNA sequences and over 125 amino acids for proteins. ...
... Homology is inferred from Similarity If two sequences are similar, then they are known as homologous sequences. Usually, at least 30% identity over 400 bp for DNA sequences and over 125 amino acids for proteins. ...
A1071 GM Canola MON88302 AppR SD1
... range compiled from results taken for seven non-GM commercial lines grown under the same conditions and c) levels recorded in the literature. A total of 69 analytes were measured of which 18 fatty acids and sodium had 50% of their values below the assay limit of quantitation and were therefore not u ...
... range compiled from results taken for seven non-GM commercial lines grown under the same conditions and c) levels recorded in the literature. A total of 69 analytes were measured of which 18 fatty acids and sodium had 50% of their values below the assay limit of quantitation and were therefore not u ...
genetics and functions of herpes simplex virus type 1 membrane
... Figure 1.2: Arrangement of the HSV-1 genome. (A) The top line represents the prototypic arrangement of the HSV-1 genome with the unique long (UL) and unique short (US) regions flanked by the terminal repeat (TR) and internal repeat (IR) regions. (B) The bottom line shows map units of the HSV-1 genom ...
... Figure 1.2: Arrangement of the HSV-1 genome. (A) The top line represents the prototypic arrangement of the HSV-1 genome with the unique long (UL) and unique short (US) regions flanked by the terminal repeat (TR) and internal repeat (IR) regions. (B) The bottom line shows map units of the HSV-1 genom ...
ETO-Thesis-Final 061214. - JScholarship
... HIV pre-exposure prophylaxis is the use of antiretroviral drugs, including dapivirine and tenofovir, in uninfected individuals to prevent the establishment of infection. Dapivirine is being developed as a topical microbicide for application to the vaginal and colorectal mucosa, and tenofovir is in c ...
... HIV pre-exposure prophylaxis is the use of antiretroviral drugs, including dapivirine and tenofovir, in uninfected individuals to prevent the establishment of infection. Dapivirine is being developed as a topical microbicide for application to the vaginal and colorectal mucosa, and tenofovir is in c ...
Kinetic studies of human tyrosyl
... C393 to G and C1629 to T that do not lead to amino acid changes, nucleotide changes of A378 to T and G481 to A lead to amino acid substitutions of R126S and G161R, respectively. Two human TDP variants containing deletion of N-terminal 39 (huTDPND39) and 174 (huTDPND174) amino acids were generated by ...
... C393 to G and C1629 to T that do not lead to amino acid changes, nucleotide changes of A378 to T and G481 to A lead to amino acid substitutions of R126S and G161R, respectively. Two human TDP variants containing deletion of N-terminal 39 (huTDPND39) and 174 (huTDPND174) amino acids were generated by ...
AMP-forming acetyl-CoA synthetases in Archaea show
... two adjacent ORFs (MTH1603-MTH1604) that together have homology to full length ACS. The DNA region from the start ATG of MTH1603 to the stop codon of MTH1604 was amplified and cloned into the pETBlue-1 expression vector, as were the genes encoding the MT-ACS2 homologs from M. thermautotrophicus stra ...
... two adjacent ORFs (MTH1603-MTH1604) that together have homology to full length ACS. The DNA region from the start ATG of MTH1603 to the stop codon of MTH1604 was amplified and cloned into the pETBlue-1 expression vector, as were the genes encoding the MT-ACS2 homologs from M. thermautotrophicus stra ...
A systems biology approach sheds new light on the regulation of
... In my years in Birmingham I had the pleasure to meet many friends and co-workers. I would like to thank them for being there to support me and I am sorry if I cannot mention all of them in this page. However, they will always be in my thoughts. The most special thanks are for my supervisor, Dr Franc ...
... In my years in Birmingham I had the pleasure to meet many friends and co-workers. I would like to thank them for being there to support me and I am sorry if I cannot mention all of them in this page. However, they will always be in my thoughts. The most special thanks are for my supervisor, Dr Franc ...
AD_________________ Award Number: W81XWH-07-1-0202
... cancer cells. However, targeting a specific gene with well-defined clinical rationale will provide a better chance of developing a more effective therapeutic agent. FAS is expressed at low or undetectable levels in most normal human tissues, with the exception of lactating breast and cycling endomet ...
... cancer cells. However, targeting a specific gene with well-defined clinical rationale will provide a better chance of developing a more effective therapeutic agent. FAS is expressed at low or undetectable levels in most normal human tissues, with the exception of lactating breast and cycling endomet ...
Environmental Microbiology
... plants (Barbieri et al., 1986). However, it has not been possible so far to construct completely IAA-negative mutants. A strain with a knockout mutation in one of the key genes in IAA synthesis still produced detectable amounts of IAA (Hartmann and Zimmer, 1994). This led to the conclusion that ther ...
... plants (Barbieri et al., 1986). However, it has not been possible so far to construct completely IAA-negative mutants. A strain with a knockout mutation in one of the key genes in IAA synthesis still produced detectable amounts of IAA (Hartmann and Zimmer, 1994). This led to the conclusion that ther ...
Provitamin A Accumulation in Cassava (Manihot
... Consequently, genetic transformation was employed to increase provitamin A content in potato tubers (Diretto et al., 2007). Provitamin A carotenoids in cassava (Manihot esculenta) have been increased threefold through conventional breeding; however, the heterozygous nature of the crop renders variet ...
... Consequently, genetic transformation was employed to increase provitamin A content in potato tubers (Diretto et al., 2007). Provitamin A carotenoids in cassava (Manihot esculenta) have been increased threefold through conventional breeding; however, the heterozygous nature of the crop renders variet ...
Identification of genes specifically required for the
... FIGURE 1 | Production of 14 CO2 by cell suspension of strains lacking Gmet 0244, Gmet 2410, or Gmet 3229 from (A) [14 C]benzene or (B) [14 C]phenol. The results are the mean and standard deviation for triplicate cell suspensions. ...
... FIGURE 1 | Production of 14 CO2 by cell suspension of strains lacking Gmet 0244, Gmet 2410, or Gmet 3229 from (A) [14 C]benzene or (B) [14 C]phenol. The results are the mean and standard deviation for triplicate cell suspensions. ...
Nutrient Sensing through the Plasma Membrane of Eukaryotic Cells
... Degradation of Mth1 (and Std1) is the key event that enables derepression of HXT gene expression. Mth1 and Std1 are marked for degradation in the proteasome (V. Brachet, unpublished work) by their ubiquitination, catalysed by the SCFGrr1 ubiquitin-protein ligase [19]. Proteins must be phosphorylated ...
... Degradation of Mth1 (and Std1) is the key event that enables derepression of HXT gene expression. Mth1 and Std1 are marked for degradation in the proteasome (V. Brachet, unpublished work) by their ubiquitination, catalysed by the SCFGrr1 ubiquitin-protein ligase [19]. Proteins must be phosphorylated ...
The Nrf2/ARE Pathway as a Potential Therapeutic Target in
... neuronal death. Current research is uncovering several conditions that are proving to be commonalities among neurodegenerative diseases. These include protein aggregation, proteasomal or autophagic dysfunction, inflammation, neuronal apoptosis, oxidative stress, mitochondrial dysfunction, and intera ...
... neuronal death. Current research is uncovering several conditions that are proving to be commonalities among neurodegenerative diseases. These include protein aggregation, proteasomal or autophagic dysfunction, inflammation, neuronal apoptosis, oxidative stress, mitochondrial dysfunction, and intera ...
Lactococcus lactis as expression host for the biosynthetic
... L. lactis strains and plasmids used in the present study are listed in Table 1. Plasmids pPA6 and pPA90 used to express the studied proteins PA6 and PA90 respectively are based on the nisininducible expression vector pNZ8048 [10]. The relevant parts of the plasmids are described in Figure 1. L. lact ...
... L. lactis strains and plasmids used in the present study are listed in Table 1. Plasmids pPA6 and pPA90 used to express the studied proteins PA6 and PA90 respectively are based on the nisininducible expression vector pNZ8048 [10]. The relevant parts of the plasmids are described in Figure 1. L. lact ...
The SRA gen - uri=dna.kdna.ucla
... Antigenic Variation-Linked Switching from Sensitivity to Resistance in ETat 1 In the ETat 1 strain of T.b. rhodesiense, the selection of R clones systematically resulted in the expression of the ETat 1.10 VSG, and counter-selection was necessary in order to generate R clones expressing different VSG ...
... Antigenic Variation-Linked Switching from Sensitivity to Resistance in ETat 1 In the ETat 1 strain of T.b. rhodesiense, the selection of R clones systematically resulted in the expression of the ETat 1.10 VSG, and counter-selection was necessary in order to generate R clones expressing different VSG ...
Biochemistry and biosynthesis of insect pigments
... and N=N are very important. Specific functional groups are also important, examples are the -NH2 and -Cl radicals, these groups tend to shift the absorptive region of a compound to longer wavelengths. If the electrons in the double bond in a pigment molecule with alternative single and double bonds ...
... and N=N are very important. Specific functional groups are also important, examples are the -NH2 and -Cl radicals, these groups tend to shift the absorptive region of a compound to longer wavelengths. If the electrons in the double bond in a pigment molecule with alternative single and double bonds ...
Molecular Cloning and Expression Analysis of IgD in Nile
... comprise the major lymphoid organs of fish, yet bone marrow and lymph nodes constitute the immune organs of mammals. The fish immune system is far simpler than that of primates and rodents [8]. It is necessary to analyze IgD in teleosts, as it will provide a reference for further research in this fi ...
... comprise the major lymphoid organs of fish, yet bone marrow and lymph nodes constitute the immune organs of mammals. The fish immune system is far simpler than that of primates and rodents [8]. It is necessary to analyze IgD in teleosts, as it will provide a reference for further research in this fi ...
pdf
... Fig. 2. Evolution of the anticodon-binding pocket of PhProRS to charge different Af-tRNAPro anticodon variants. (A) Anticodon-binding site of ProRS in the crystal structure from T. thermophilus. The consensus sequence of the proline anticodon (GG), shown in magenta, interacts strongly with the amino ...
... Fig. 2. Evolution of the anticodon-binding pocket of PhProRS to charge different Af-tRNAPro anticodon variants. (A) Anticodon-binding site of ProRS in the crystal structure from T. thermophilus. The consensus sequence of the proline anticodon (GG), shown in magenta, interacts strongly with the amino ...
The deleterious effect of missense mutations on pre
... (b) affect an invariant splice junction consensus sequence, or (c) were previously reported as pathogenic in the literature based on supporting functional data (Cotton and Scriver 1999). These criteria are not fulfilled if a missense mutation is detected. It is possible that the predicted amino acid ...
... (b) affect an invariant splice junction consensus sequence, or (c) were previously reported as pathogenic in the literature based on supporting functional data (Cotton and Scriver 1999). These criteria are not fulfilled if a missense mutation is detected. It is possible that the predicted amino acid ...
Nucleotide sequence and structural organization of
... O R F C of pWVO1, believed to encode the repressor protein regulating synthesis of the replication initiation protein (Leenhouts e t al., 1991). There was no apparent similarity between ORF3 and other D N A or protein sequences in the data banks. The homology of the translated peptide product of ORF ...
... O R F C of pWVO1, believed to encode the repressor protein regulating synthesis of the replication initiation protein (Leenhouts e t al., 1991). There was no apparent similarity between ORF3 and other D N A or protein sequences in the data banks. The homology of the translated peptide product of ORF ...
Gene Section SOX10 (SRY (sex determining region Y)-box 10)
... Nonaka D, Chiriboga L, Rubin BP. Sox10: a pan-schwannian and melanocytic marker. Am J Surg Pathol. 2008 Sep;32(9):1291-8 Blochin E, Nonaka D. Diagnostic value of Sox10 immunohistochemical staining for the detection of metastatic melanoma in sentinel lymph nodes. Histopathology. 2009 ...
... Nonaka D, Chiriboga L, Rubin BP. Sox10: a pan-schwannian and melanocytic marker. Am J Surg Pathol. 2008 Sep;32(9):1291-8 Blochin E, Nonaka D. Diagnostic value of Sox10 immunohistochemical staining for the detection of metastatic melanoma in sentinel lymph nodes. Histopathology. 2009 ...
Molecular Plant-Microbe Interactions
... free-living soil bacteria are still lacking. Synthesis of IAA by the gram-positive phytopathogen Rhodococcus fascians recently was reported (Vandeputte et al. 2005). Gas chromatographymass spectrometry (GC-MS) analysis verified gibberellin production by B. pumilus and B. licheniformis (Gutierrez-Mar ...
... free-living soil bacteria are still lacking. Synthesis of IAA by the gram-positive phytopathogen Rhodococcus fascians recently was reported (Vandeputte et al. 2005). Gas chromatographymass spectrometry (GC-MS) analysis verified gibberellin production by B. pumilus and B. licheniformis (Gutierrez-Mar ...
Purified Hexameric Epstein-Barr Virus-Encoded BARF1 Protein for Measuring Anti-BARF1 Antibody
... BARF1 protein expression in carcinoma tissue has proven extremely difficult, although one report described its presence in NPC tumor extracts (5). Recently, it was shown that BARF1 lacking the first 20 amino acids is actively secreted (6, 7, 30), and BARF1 protein was detected in sera of NPC patient ...
... BARF1 protein expression in carcinoma tissue has proven extremely difficult, although one report described its presence in NPC tumor extracts (5). Recently, it was shown that BARF1 lacking the first 20 amino acids is actively secreted (6, 7, 30), and BARF1 protein was detected in sera of NPC patient ...
Endogenous retrovirus
Endogenous retroviruses (ERVs) are endogenous viral elements in the genome that closely resemble and can be derived from retroviruses. They are abundant in the genomes of jawed vertebrates, and they comprise up to 5–8% of the human genome (lower estimates of ~1%). ERVs are a subclass of a type of gene called a transposon, which can be packaged and moved within the genome to serve a vital role in gene expression and in regulation. Researchers have suggested that retroviruses evolved from a type of transposable gene called a retrotransposon, which includes ERVs; these genes can mutate and instead of moving to another location in the genome they can become exogenous or pathogenic. This means that all ERVs may not have originated as an insertion by a retrovirus but that some may have been the source for the genetic information in the retroviruses they resemble.