Polymer scaling laws of unfolded and intrinsically disordered
... t has become increasingly clear that the structure and dynamics of unfolded proteins are essential for understanding protein folding (1–3) and the functional properties of intrinsically disordered proteins (IDPs) (4–6). Theoretical concepts from polymer physics (7–9) have frequently been used to des ...
... t has become increasingly clear that the structure and dynamics of unfolded proteins are essential for understanding protein folding (1–3) and the functional properties of intrinsically disordered proteins (IDPs) (4–6). Theoretical concepts from polymer physics (7–9) have frequently been used to des ...
PDF
... t has become increasingly clear that the structure and dynamics of unfolded proteins are essential for understanding protein folding (1–3) and the functional properties of intrinsically disordered proteins (IDPs) (4–6). Theoretical concepts from polymer physics (7–9) have frequently been used to des ...
... t has become increasingly clear that the structure and dynamics of unfolded proteins are essential for understanding protein folding (1–3) and the functional properties of intrinsically disordered proteins (IDPs) (4–6). Theoretical concepts from polymer physics (7–9) have frequently been used to des ...
0 - Microbiology
... another family of bacteria, the Enterobacteriaceae. Recombination by conjugation and transduction The relationship between genetic constitution and biochemical function had emerged from the combination of biochemical and genetical analysis that Beadle & Tatum (1941) had so successfully employed with ...
... another family of bacteria, the Enterobacteriaceae. Recombination by conjugation and transduction The relationship between genetic constitution and biochemical function had emerged from the combination of biochemical and genetical analysis that Beadle & Tatum (1941) had so successfully employed with ...
Saccharomyces cerevisiae.
... Another industrial interest in anaerobic growth arises because of the problems with oxygen gradients encountered in voluminous aerobic fermentations. High cell densities required for the production of heterologous proteins may lead to gradients in the oxygen concentration as a result of imperfect mi ...
... Another industrial interest in anaerobic growth arises because of the problems with oxygen gradients encountered in voluminous aerobic fermentations. High cell densities required for the production of heterologous proteins may lead to gradients in the oxygen concentration as a result of imperfect mi ...
Discovery of Proteomic Code with mRNA Assisted Protein Folding
... connect codons to their coded amino acids. The wobble base lost its importance because of its interchangeability. Most scientific efforts focused on to find stereo-chemical compatibility (spatial fitting) between the atomic geometry defined by 2 or 3 nucleic acid bases and the corresponding geometry ...
... connect codons to their coded amino acids. The wobble base lost its importance because of its interchangeability. Most scientific efforts focused on to find stereo-chemical compatibility (spatial fitting) between the atomic geometry defined by 2 or 3 nucleic acid bases and the corresponding geometry ...
Proteomic Analysis of Neisseria gonorrhoeae Biofilms
... critical to better understand the biochemical signals that regulate biofilm formation and maintenance. During the past decade, there have been various genomic [14,15] and proteomic [16] studies of biofilm formation, driven in part by technical advances in microarrays and mass spectrometry-based prot ...
... critical to better understand the biochemical signals that regulate biofilm formation and maintenance. During the past decade, there have been various genomic [14,15] and proteomic [16] studies of biofilm formation, driven in part by technical advances in microarrays and mass spectrometry-based prot ...
Phospholipid synthesis in Borrelia burgdorferi: BB0249 and BB0721
... protocols (Ames, 1968) and TLC of the extracts was performed. Staining of the TLC plates confirmed that PC and PG are the major phospholipids in the B. burgdorferi membrane (data not shown) and suggested that this method was a reliable method for examining B. burgdorferi membrane phospholipids. We t ...
... protocols (Ames, 1968) and TLC of the extracts was performed. Staining of the TLC plates confirmed that PC and PG are the major phospholipids in the B. burgdorferi membrane (data not shown) and suggested that this method was a reliable method for examining B. burgdorferi membrane phospholipids. We t ...
Sequence Specific Modeling of E. coli Cell-Free Protein
... organisms, including industrially important prokaryotes such as E. coli (19) and B. subtilis (20), are now available (21). Stoichiometric reconstructions have been expanded to include the integration of metabolism with detailed descriptions of gene expression (ME-Model) (17, 22) and protein structur ...
... organisms, including industrially important prokaryotes such as E. coli (19) and B. subtilis (20), are now available (21). Stoichiometric reconstructions have been expanded to include the integration of metabolism with detailed descriptions of gene expression (ME-Model) (17, 22) and protein structur ...
Linking folding and binding
... sequences [1,21]. Indeed, it is frequently possible to identify these folding motifs, which have been termed molecular recognition elements or MoRFs, by bioinformatic analysis of the protein sequence [22]. These recognition motifs can fold into helix, b-strand, or form irregular structure on bindin ...
... sequences [1,21]. Indeed, it is frequently possible to identify these folding motifs, which have been termed molecular recognition elements or MoRFs, by bioinformatic analysis of the protein sequence [22]. These recognition motifs can fold into helix, b-strand, or form irregular structure on bindin ...
Bioinformatics
... information than Madonna's genome. And Madonna shares 99% of her DNA with a chimp...And 90% with Craig Venter’s dog.” More proof that the genome is not a lot of data: About 90-something percent of genetic information is common to all humans. "The unique part of you will fit on a floppy disk." Nathan ...
... information than Madonna's genome. And Madonna shares 99% of her DNA with a chimp...And 90% with Craig Venter’s dog.” More proof that the genome is not a lot of data: About 90-something percent of genetic information is common to all humans. "The unique part of you will fit on a floppy disk." Nathan ...
CHAPTER 13 DNA manipulation
... faulty gene. (The embryos came from an in-vitro clinic and, because each was the product of fertilisation by two sperm, these embryos were not capable of completing development.) The results of their experiments appear to have raised many questions and few answers. Issues being debated include: Shou ...
... faulty gene. (The embryos came from an in-vitro clinic and, because each was the product of fertilisation by two sperm, these embryos were not capable of completing development.) The results of their experiments appear to have raised many questions and few answers. Issues being debated include: Shou ...
Lecture Notes for Methods in Cell Biology
... This course provides students with a broad overview to the basic biochemical, molecular and immunological techniques that are commonly used in modern biomedical research. Lectures will describe the theories and principals behind each of the methods in addition to discussing the practical aspects and ...
... This course provides students with a broad overview to the basic biochemical, molecular and immunological techniques that are commonly used in modern biomedical research. Lectures will describe the theories and principals behind each of the methods in addition to discussing the practical aspects and ...
Review Non-ribosomal peptide synthetases: Identifying the cryptic
... the NRPS (Lambalot et al. 1996). Non-ribosomal peptide contains both L and D amino acids and these D-amino acids are especially generated by an epimerase encoded in the cluster, which acts on the activated aminoacyl thioester. The condensation domain just downstream of a D-amino acid contributing mo ...
... the NRPS (Lambalot et al. 1996). Non-ribosomal peptide contains both L and D amino acids and these D-amino acids are especially generated by an epimerase encoded in the cluster, which acts on the activated aminoacyl thioester. The condensation domain just downstream of a D-amino acid contributing mo ...
Cloning and Expression of Bovine Sodium/Glucose Cotransporters* J. Dairy Sci. 88:182–194
... and Trayhurn, 2003). In most tissues and cells, glucose is transported by a bidirectional and energy-independent process mediated by members of the facilitative glucose transporter family (solute carriers SLC2A, protein symbol GLUT). However, in a few cell types, glucose is transported by an active, ...
... and Trayhurn, 2003). In most tissues and cells, glucose is transported by a bidirectional and energy-independent process mediated by members of the facilitative glucose transporter family (solute carriers SLC2A, protein symbol GLUT). However, in a few cell types, glucose is transported by an active, ...
phylogenetic analysis of the rompb genes of rickettsia felis and
... One of the rickettsial major surface proteins has been referred to as rickettsial outer membrane protein B (rOmpB). The interest in this protein results from its major quantity and outer membrane location and the strong immune response observed after infection, suggesting an important yet undefined ...
... One of the rickettsial major surface proteins has been referred to as rickettsial outer membrane protein B (rOmpB). The interest in this protein results from its major quantity and outer membrane location and the strong immune response observed after infection, suggesting an important yet undefined ...
STRUCTURE AND ALLERGENICITY OF WHEAT GLUTEN PROTEINS
... A different structural model exists for the highest molecular weight gliadins. Omega-gliadins contain short, distinct C and N terminal sequences, separated by a region of repeatable sequences similar to γ gliadins. The sequence differs from that of γ gliadins, however, in having additional glutamine ...
... A different structural model exists for the highest molecular weight gliadins. Omega-gliadins contain short, distinct C and N terminal sequences, separated by a region of repeatable sequences similar to γ gliadins. The sequence differs from that of γ gliadins, however, in having additional glutamine ...
Spinalin, a new glycine- and histidine
... and operculum of Hydra nematocysts. Spinalin cDNA clones were identified by in situ hybridization to differentiating nematocytes. Sequencing of a full-length clone revealed the presence of an N-terminal signal peptide, suggesting that the mature protein is sorted via the endoplasmic reticulum to the ...
... and operculum of Hydra nematocysts. Spinalin cDNA clones were identified by in situ hybridization to differentiating nematocytes. Sequencing of a full-length clone revealed the presence of an N-terminal signal peptide, suggesting that the mature protein is sorted via the endoplasmic reticulum to the ...
Molecular identification of three Arabidopsis thaliana mitochondrial
... of several small insertions in a segment of DIC3 located after the first 36 N-terminal residues (Figure 1). Therefore DIC1 and DIC2 are more closely related, as is also indicated by the fact that their genes contain no introns, whereas the DIC3 gene possesses a canonical type II intron spanning the ...
... of several small insertions in a segment of DIC3 located after the first 36 N-terminal residues (Figure 1). Therefore DIC1 and DIC2 are more closely related, as is also indicated by the fact that their genes contain no introns, whereas the DIC3 gene possesses a canonical type II intron spanning the ...
E. coli
... Glutamine synthetase reaction mechanism ATP binds to GS glutamate binds to (E.ATP) E.ATP.glu ----> E.ADP.glutamyl-g-P ...
... Glutamine synthetase reaction mechanism ATP binds to GS glutamate binds to (E.ATP) E.ATP.glu ----> E.ADP.glutamyl-g-P ...
View PDF - DNA and Natural Algorithms Group
... and stacking are the two dominant factors for affinity and discrimination. While there is a simple and common motif for adenine binding, other sequences and structures are also possible (just as there are other ways that proteins can interact with adenosine other than the Rossman fold). An anti-CoA ...
... and stacking are the two dominant factors for affinity and discrimination. While there is a simple and common motif for adenine binding, other sequences and structures are also possible (just as there are other ways that proteins can interact with adenosine other than the Rossman fold). An anti-CoA ...
SPT4, a gene important for tr
... DNA sequence analysis. DNA fragments were cloned in the vectors M13mpl8 and M13mpl9 (Norrander et al. 1983) and sequenced by the dideoxy chain-termination method (Sanger et al. 1977) using [a35S] dATP (New England Nuclear, Boston, Mass) and Sequenase (US Biochemical, Cleveland, Ohio). All sequences ...
... DNA sequence analysis. DNA fragments were cloned in the vectors M13mpl8 and M13mpl9 (Norrander et al. 1983) and sequenced by the dideoxy chain-termination method (Sanger et al. 1977) using [a35S] dATP (New England Nuclear, Boston, Mass) and Sequenase (US Biochemical, Cleveland, Ohio). All sequences ...