Pyruvate : NADP+ Oxidoreductase from the Mitochondrion of
... the earliest eukaryotic cells (Martin and Müller 1998). In principle, three alternative explanations could currently account for the distribution of PFO among eukaryotes and its evident correlation with the amitochondriate phenotype. The first possible explanation is that the host of mitochondrial ...
... the earliest eukaryotic cells (Martin and Müller 1998). In principle, three alternative explanations could currently account for the distribution of PFO among eukaryotes and its evident correlation with the amitochondriate phenotype. The first possible explanation is that the host of mitochondrial ...
The Genetic Code and RNA-Amino Acid Affinities
... functional nucleotides, the number of “Implicated Site Nucleotides” (ISN). Implicated Site Nucleotides differ from the constellation of atoms also called nucleotides by a structural biologist, and sometimes the distinction is essential. Though usually obvious, site nucleotides can occasionally be el ...
... functional nucleotides, the number of “Implicated Site Nucleotides” (ISN). Implicated Site Nucleotides differ from the constellation of atoms also called nucleotides by a structural biologist, and sometimes the distinction is essential. Though usually obvious, site nucleotides can occasionally be el ...
Practical Aspects of Estimating Energy Components in
... cdk1 phosphorylates p62 in vitro and in vivo at T269 and S272, which is necessary for the maintenance of appropriate cyclin B1 levels and the levels of cdk1 activity necessary to allow cells to properly enter and exit mitosis. ...
... cdk1 phosphorylates p62 in vitro and in vivo at T269 and S272, which is necessary for the maintenance of appropriate cyclin B1 levels and the levels of cdk1 activity necessary to allow cells to properly enter and exit mitosis. ...
Comparison of the Structure of the Extrinsic 33 kDa Protein from
... the 33 kDa protein cDNA were amplified using primers newly synthesized based on the 469-bp cDNA fragment, which yielded a 565-bp cDNA fragment and a 640-bp cDNA fragment from 5¢- and 3¢-RACE, respectively. The nucleotide sequences of these cDNA fragments were confirmed to contain the cDNA for the 33 ...
... the 33 kDa protein cDNA were amplified using primers newly synthesized based on the 469-bp cDNA fragment, which yielded a 565-bp cDNA fragment and a 640-bp cDNA fragment from 5¢- and 3¢-RACE, respectively. The nucleotide sequences of these cDNA fragments were confirmed to contain the cDNA for the 33 ...
IMGT-ONTOLOGY and IMGT databases, tools and Web
... IMGT standardized keywords, based on the IDENTIFICATION concept, have been assigned to all IMGT/LIGM-DB entries. They include (i) general keywords: indispensable for the sequence assignments, they are described in an exhaustive and non-redundant list, and are organized in a tree structure, and (ii) ...
... IMGT standardized keywords, based on the IDENTIFICATION concept, have been assigned to all IMGT/LIGM-DB entries. They include (i) general keywords: indispensable for the sequence assignments, they are described in an exhaustive and non-redundant list, and are organized in a tree structure, and (ii) ...
Engineering primary metabolic pathways of industrial
... genes that confer a prominent phenotype when the responsible mutation(s) are anywhere on the genome, but not at the place of the coding gene itself. For example, over-expression of certain sigma factors enhanced protein production in stationary phase (Weikert et al., 2000). Screening of libraries to ...
... genes that confer a prominent phenotype when the responsible mutation(s) are anywhere on the genome, but not at the place of the coding gene itself. For example, over-expression of certain sigma factors enhanced protein production in stationary phase (Weikert et al., 2000). Screening of libraries to ...
tutorial - ppuigbo
... CAIcal has three main options: a) Calculation of parameters. This initial option provides basic calculations such as nucleotide composition, codon usage, codon usage per thousand and relative synonymous codon usage (RSCU) (see section A of this guide). b) CAI calculation for FASTA sequences. This se ...
... CAIcal has three main options: a) Calculation of parameters. This initial option provides basic calculations such as nucleotide composition, codon usage, codon usage per thousand and relative synonymous codon usage (RSCU) (see section A of this guide). b) CAI calculation for FASTA sequences. This se ...
Research Associate, Dept
... characterized and display significant differences from mammalian homologues. Together with the fact that C. parvum polyamine biosynthesis differs significantly from that of its host (using arginine- instead of ornithine decarboxylase to produce putrescine), and that the back-conversion pathways are ...
... characterized and display significant differences from mammalian homologues. Together with the fact that C. parvum polyamine biosynthesis differs significantly from that of its host (using arginine- instead of ornithine decarboxylase to produce putrescine), and that the back-conversion pathways are ...
here - Institute of Human Genetics
... convulsions, irritability and vomiting and acidosis. If not treated properly and immediately, it might lead to serious brain damage and death. Once these signs and symptoms are present, please bring your child to the hospital for management and alert your pediatrician or metabolic physician. ...
... convulsions, irritability and vomiting and acidosis. If not treated properly and immediately, it might lead to serious brain damage and death. Once these signs and symptoms are present, please bring your child to the hospital for management and alert your pediatrician or metabolic physician. ...
Recombinant expression and characterisation of monofunctional S-
... domains. The deduced amino acid sequence of the bifunctional PfAdoMetDC/ODC predicted a molecular mass of 166 kDa for the polypeptide, whereas the recombinantly expressed enzyme had a molecular mass of -330 kDa. This suggested that the enzyme consists of a heterotetrameric structure derived from two ...
... domains. The deduced amino acid sequence of the bifunctional PfAdoMetDC/ODC predicted a molecular mass of 166 kDa for the polypeptide, whereas the recombinantly expressed enzyme had a molecular mass of -330 kDa. This suggested that the enzyme consists of a heterotetrameric structure derived from two ...
Nucleosides, Nucleotides,Nucleic Acids
... Watson and Crick proposed a double-stranded structure for DNA in which a purine or pyrimidine base in one chain is hydrogen bonded to its complement in the other. •Gives proper Chargaff ratios (A=T and G=C) •Because each pair contains one purine and one pyrimidine, the A---T and G---C distances betw ...
... Watson and Crick proposed a double-stranded structure for DNA in which a purine or pyrimidine base in one chain is hydrogen bonded to its complement in the other. •Gives proper Chargaff ratios (A=T and G=C) •Because each pair contains one purine and one pyrimidine, the A---T and G---C distances betw ...
Differential Regulation of a-Lactalbumin and
... gland on various days of pregnancy and lactation. Chart 8 pups during lactation; casein messenger levels are dimin shows total protein synthesized as a function of the pg of ished (Chart 9A). When a-lactalbumin mRNA activity was measured at RNA added to the translation system. It is apparent from th ...
... gland on various days of pregnancy and lactation. Chart 8 pups during lactation; casein messenger levels are dimin shows total protein synthesized as a function of the pg of ished (Chart 9A). When a-lactalbumin mRNA activity was measured at RNA added to the translation system. It is apparent from th ...
patrick_tb_ch17
... Feedback: Aciclovir is phosphorylated by viral thymidine kinase to the monophosphate which is then taken on to the active triphosphate by the action of cellular kinases. Aciclovir is a poor substrate for cellular thymidine kinase and so the drug is activated more slowly in non-infected cells. There ...
... Feedback: Aciclovir is phosphorylated by viral thymidine kinase to the monophosphate which is then taken on to the active triphosphate by the action of cellular kinases. Aciclovir is a poor substrate for cellular thymidine kinase and so the drug is activated more slowly in non-infected cells. There ...
Flavors of Protein Disorder
... Keywords: secondary structure, structure prediction, genomics, sequence composition, signaling and regulatory proteins, unfolded proteins ...
... Keywords: secondary structure, structure prediction, genomics, sequence composition, signaling and regulatory proteins, unfolded proteins ...
The Role of Carbohydrate Response Element Binding Protein in
... deletion protects against high sucrose diet-induced and leptin-deficient obesity, because Chrebp−/− mice cannot consume fructose or sucrose. Moreover, ChREBP contributes to some of the physiological effects of fructose on sweet taste preference and glucose production through regulation of ChREBP tar ...
... deletion protects against high sucrose diet-induced and leptin-deficient obesity, because Chrebp−/− mice cannot consume fructose or sucrose. Moreover, ChREBP contributes to some of the physiological effects of fructose on sweet taste preference and glucose production through regulation of ChREBP tar ...
Glycolysis Lecture
... clearly what is expected from you to achieve together with the evaluation procedures. There is no reason to suppose that Biochemistry is intrinsically uninteresting, difficult to understand or an obstacle to be overcome during your progress to a professional qualifications. In the contrary you can e ...
... clearly what is expected from you to achieve together with the evaluation procedures. There is no reason to suppose that Biochemistry is intrinsically uninteresting, difficult to understand or an obstacle to be overcome during your progress to a professional qualifications. In the contrary you can e ...
The use of glycogen and GlycoBlue reagent in Qubit DNA and RNA
... (within 5% of controls) in all four assays tested: the Qubit dsDNA HS, dsDNA BR, RNA BR, and RNA HS assays. Similarly, nucleic acid samples containing 500 ng/μL of GlycoBlue Coprecipitant (25 ng/μL in the assay tube) were quantified accurately in three of the assays tested: the Qubit dsDNA HS, dsDNA ...
... (within 5% of controls) in all four assays tested: the Qubit dsDNA HS, dsDNA BR, RNA BR, and RNA HS assays. Similarly, nucleic acid samples containing 500 ng/μL of GlycoBlue Coprecipitant (25 ng/μL in the assay tube) were quantified accurately in three of the assays tested: the Qubit dsDNA HS, dsDNA ...
In vitro conjugal transfer of tetracycline resistance from Lactobacillus
... which showed a high sequence homology of its replicon with that of a Tetragenococcus halophilus plasmid [10]. The host range of the latter plasmid was previously shown to include the genera Pediococcus, Enterococcus, Lactobacillus and Leuconostoc but not the genus Lactococcus [23]. Our ¢ndings indic ...
... which showed a high sequence homology of its replicon with that of a Tetragenococcus halophilus plasmid [10]. The host range of the latter plasmid was previously shown to include the genera Pediococcus, Enterococcus, Lactobacillus and Leuconostoc but not the genus Lactococcus [23]. Our ¢ndings indic ...
nitrogen fixation and its improvement through genetic engineering
... the reduction of biological nitrogen. Four principal classes of nitrogenases have been characterized (Eady RR, 1996) out of which three have nearly similar characteristic features which differs only by the heterometal atom present in the active site metal cluster (Mo, V or Fe). The fourth class isol ...
... the reduction of biological nitrogen. Four principal classes of nitrogenases have been characterized (Eady RR, 1996) out of which three have nearly similar characteristic features which differs only by the heterometal atom present in the active site metal cluster (Mo, V or Fe). The fourth class isol ...
A structural determinant in the uracil DNA glycosylase superfamily
... analysis presented here demonstrates that a K68N substitution not only allows E. coli MUG to act on A/U base pairs, but also increases its catalytic efficiency on all other double-stranded uracil-containing DNA. Binding analysis shows that the substitution enhances the binding affinity of K68N to al ...
... analysis presented here demonstrates that a K68N substitution not only allows E. coli MUG to act on A/U base pairs, but also increases its catalytic efficiency on all other double-stranded uracil-containing DNA. Binding analysis shows that the substitution enhances the binding affinity of K68N to al ...
ELM1 is required for multidrug resistance in
... between isogenic PDR1 and pdr1-3 strains. We demonstrated that Pdr1 is constitutively bound to the PDR5 promoter. Cycloheximide induction in the wild-type PDR1 strain alters the nucleosome structure at the PDR5 upstream activating sequence (UAS) region harboring PDRE. These alternations reflect chan ...
... between isogenic PDR1 and pdr1-3 strains. We demonstrated that Pdr1 is constitutively bound to the PDR5 promoter. Cycloheximide induction in the wild-type PDR1 strain alters the nucleosome structure at the PDR5 upstream activating sequence (UAS) region harboring PDRE. These alternations reflect chan ...
Comparative Analysis of Prothrombin Activators
... activator, present only in snakes containing group C complexes, also showed a very high degree of homology (96%–98%). Expression of both the factor X– and factor V–like proteins determined by immunoblotting provided an additional means of separating these two groups at the molecular level. The molec ...
... activator, present only in snakes containing group C complexes, also showed a very high degree of homology (96%–98%). Expression of both the factor X– and factor V–like proteins determined by immunoblotting provided an additional means of separating these two groups at the molecular level. The molec ...
Supporting document 1 Safety assessment
... organism in plant biology and genetics and its genome was the first plant genome to be fully sequenced. The 125 megabase genome of A. thaliana contains 25,498 predicted genes, organised into five chromosomes, encoding proteins from 11,000 families (Arabidopsis Genome Initiative 2000). Although a mem ...
... organism in plant biology and genetics and its genome was the first plant genome to be fully sequenced. The 125 megabase genome of A. thaliana contains 25,498 predicted genes, organised into five chromosomes, encoding proteins from 11,000 families (Arabidopsis Genome Initiative 2000). Although a mem ...