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LEA proteins in higher plants: Structure, function, gene expression
LEA proteins in higher plants: Structure, function, gene expression

... 3. LEA protein structure LEA proteins in higher plants are mainly composed of hydrophilic amino acids ordered in repeated sequence (e.g. Gly and Lys), forming hyper-hydrophilicness and thermal stability. Advanced structure of such protein contains nonperiodic linear and ␣-helixed structure without t ...
video slide - Buena Park High School
video slide - Buena Park High School

... 2 Elongation. The polymerase moves downstream, unwinding the DNA and elongating the RNA transcript 5  3 . In the wake of transcription, the DNA strands re-form a double helix. ...
Molecular motors: DNA takes control
Molecular motors: DNA takes control

... kinetically stable, Turberfield and colleagues show that they can be disassembled by using the strand-displacement mechanism to break the DNA link between motors in complexes that are situated at the centre of the aster (Fig. 1b, steps 3–4). Simply adding single-stranded DNA oligonucleotides to the ...
and ways to find them
and ways to find them

... decompressor are needed to see this picture. ...
Biotechnology Laboratory (Kallas)
Biotechnology Laboratory (Kallas)

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Introduction
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... Lactose is found in milk but not in many other environments. It would, therefore, be a waste of energy if the gene for β-galactosidase was permanently switched on. It would be more efficient if the E.coli could switch the gene on only when its enzyme was required. Two scientists, Jacob & Monod put f ...
Regulation of transcription by Saccharomyces cerevisiae 14-3
Regulation of transcription by Saccharomyces cerevisiae 14-3

... bmh2 mutant by the disruption of both BMH genes and the introduction of a mutated bmh2 allele [24]. We used this mutant to identify extragenic suppressor mutations bypassing the requirement of active 14-3-3 proteins. Recessive mutations in RTG3 and SIN4 resulted in growth at the restrictive temperat ...
5 min Insect DNA/RNA Preservation and Extraction Kit
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The different roles of tryptophan transfer RNA in regulating trp
The different roles of tryptophan transfer RNA in regulating trp

... of each amino acid and/or its corresponding charged tRNAs, and enable an appropriate response that would adjust their rate of synthesis. Often both an amino acid and its charged or uncharged tRNA serve as regulatory signals. This double sensing is essential because the concentration of each signal m ...
PITT pGLO Transformation Lab Protocol
PITT pGLO Transformation Lab Protocol

... is interrupted by non-coding sequences introns Requires RNA splicing to convert premRNA (primary transcript; exons + introns) into mRNA (exons) ...
GD Reagent (Genomic DNA Isolation Reagent)
GD Reagent (Genomic DNA Isolation Reagent)

... The DNA is isolated from proteins by several methods, including the digestion of proteins by the enzyme proteinase K. The proteins are removed subsequently by salting-out, organic extraction, or binding of the DNA to a solid-phase support (such as an anion-exchange column or silica technology). The ...
Motif Finding
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LECTURE #25: Translation
LECTURE #25: Translation

... into protein with help from transfer RNA (tRNA)  Each carries a specific amino acid  “t” shape  Carries amino acids  Matches codons to anticodons ...
MULTIPLE CHOICE. Choose the one alternative that best completes
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Chapter 4 (part 3)
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... Allosteric Interactions • Allosteric interaction occur when specific molecules bind a protein and modulates activity • Allosteric modulators or allosteric effectors • Bind reversibly to site separate from functional binding or active site • Modulation of activity occurs through change in protein co ...
Light behind the curtain: photoregulation of nuclear architecture and
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... Transcriptional corepressors are commonly associated with DNAbinding proteins that contain repressive motifs, such as the plantspecific ethylene-responsive element binding factor-associated amphiphilic repression (EAR) motif (Kagale & Rozwadowski, 2011). Such multiprotein complexes bridging transcri ...
mRNA and protein abundance for glutathione-S
mRNA and protein abundance for glutathione-S

... Comprehensive identification of all functional elements encoded in the human genome is a fundamental need in biomedical research. Here, we present a comparative analysis of the human, mouse, rat and dog genomes to create a systematic catalogue of common regulatory motifs in promoters and 3' untransl ...
Cell and Molecular Biology
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... ubiquitin ligases via different mechanisms. www.soran.edu.iq ...
Sbjct = Alu sequence
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Full text PDF
Full text PDF

... the amino terminus of CRTC2 consist of alpha helix structure, and directly bind to leucine zipper region of CREB. Since alpha helix of CRTC2 lacks basic amino acids, CRTC2 is not directly involved in the DNA binding, but promotes stronger interaction among CREB, CRTC2 and its cognate DNA (containing ...
RevertAid First Strand cDNA Synthesis Kit, #K1621
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A Discovery Laboratory Investigating Bacterial Gene Regulation
A Discovery Laboratory Investigating Bacterial Gene Regulation

... The repressor of the lactose operon is coded for by the lac I gene. The repressor binds to the operator area, O, and blocks the attachment of the RNA polymerase to the promoter site, P. RNA polymerase must attach to the promoter site and move through the operator site if the lactose operon is to be ...
RnaUs Total Viral RNA/DNA Prep
RnaUs Total Viral RNA/DNA Prep

... and centrifuge at 12,000 rpm for 2 min. The RNA is in the flow-through liquid. Store the RNA solution o at -20 C. Note: It is highly recommended that RNA quality be determined before downstream applications. The quality of RNA can be assessed by denatured agarose gel electrophoresis with the ethidiu ...
2.6 Structure of DNA and RNA
2.6 Structure of DNA and RNA

... nucleotides of DNA and RNA, using circles, shape does not need to be shown, but the two pentagons and rectangles to represent phosphates, strands should be shown antiparallel. Adenine pentoses and bases. should be shown paired with thymine and guanine with cytosine, but the relative lengths of the p ...
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Transcriptional regulation

In molecular biology and genetics, transcriptional regulation is the means by which a cell regulates the conversion of DNA to RNA (transcription), thereby orchestrating gene activity. A single gene can be regulated in a range of ways, from altering the number of copies of RNA that are transcribed, to the temporal control of when the gene is transcribed. This control allows the cell or organism to respond to a variety of intra- and extracellular signals and thus mount a response. Some examples of this include producing the mRNA that encode enzymes to adapt to a change in a food source, producing the gene products involved in cell cycle specific activities, and producing the gene products responsible for cellular differentiation in higher eukaryotes.The regulation of transcription is a vital process in all living organisms. It is orchestrated by transcription factors and other proteins working in concert to finely tune the amount of RNA being produced through a variety of mechanisms. Prokaryotic organisms and eukaryotic organisms have very different strategies of accomplishing control over transcription, but some important features remain conserved between the two. Most importantly is the idea of combinatorial control, which is that any given gene is likely controlled by a specific combination of factors to control transcription. In a hypothetical example, the factors A and B might regulate a distinct set of genes from the combination of factors A and C. This combinatorial nature extends to complexes of far more than two proteins, and allows a very small subset (less than 10%) of the genome to control the transcriptional program of the entire cell.
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