Immobilization and stretching of DNA molecules in a
... A new technique can immobilize and stretch a large number of DNA molecules for single-molecule DNA analysis applications. DNA-protein interactions drive the cellular machinery for maintaining and transcribing DNA. To study the motion and kinetics of proteins along a DNA strand at the single-molecule ...
... A new technique can immobilize and stretch a large number of DNA molecules for single-molecule DNA analysis applications. DNA-protein interactions drive the cellular machinery for maintaining and transcribing DNA. To study the motion and kinetics of proteins along a DNA strand at the single-molecule ...
VNTR, STR and RFLP
... – Location in a genome where a short nucleotide is organized as a tandem repeat – These can be found on many chromosomes and often show variations in length – Each variant acts as an inherited allele allowing used for identification – Useful in genetics, biology research, forensics and DNA fingerpri ...
... – Location in a genome where a short nucleotide is organized as a tandem repeat – These can be found on many chromosomes and often show variations in length – Each variant acts as an inherited allele allowing used for identification – Useful in genetics, biology research, forensics and DNA fingerpri ...
Felis domesticus papillomavirus, isolated from a skin lesion, is
... We have determined the complete nucleotide sequence of a PV isolated and cloned from a domestic cat with cutaneous papillomatous lesions. FdPV is most closely related to COPV by amino acid and nucleotide sequence homology and contains the novel NCR-2 region. PVs are considered highly speciesspecific ...
... We have determined the complete nucleotide sequence of a PV isolated and cloned from a domestic cat with cutaneous papillomatous lesions. FdPV is most closely related to COPV by amino acid and nucleotide sequence homology and contains the novel NCR-2 region. PVs are considered highly speciesspecific ...
Snímek 1
... sequester RNA binding proteins and lead to a loss of their normal function. For example, in myotonic dystrophy, CUG(G) expanded RNA transcripts sequester MBNL proteins from their normal splicing targets leading to a MBNL loss-of-function and alternative splicing dysregulation. The recent discovery o ...
... sequester RNA binding proteins and lead to a loss of their normal function. For example, in myotonic dystrophy, CUG(G) expanded RNA transcripts sequester MBNL proteins from their normal splicing targets leading to a MBNL loss-of-function and alternative splicing dysregulation. The recent discovery o ...
清华大学本科生考试试题专用纸
... not only are unable to use glucose properly but also fail to synthesize fatty acids from carbohydrates or amino acids. Untreated diabetics have increased rate of fat oxidation and ketone body formation, as a consequence, lose weight. 43. Suppose that a bacterial mutant is found to replicate its DNA ...
... not only are unable to use glucose properly but also fail to synthesize fatty acids from carbohydrates or amino acids. Untreated diabetics have increased rate of fat oxidation and ketone body formation, as a consequence, lose weight. 43. Suppose that a bacterial mutant is found to replicate its DNA ...
Faulty ribosomes and human diseases: mistakes in “assembly line
... Mobile : +91 70221 29624 E-mail : [email protected] Abstract Ribosomes are molecular machineries that decode the information within mRNAs and generate all the proteins required for cellular activities. Ribosomes are essential to every living organism. The synthesis of ribosome is an intricate pro ...
... Mobile : +91 70221 29624 E-mail : [email protected] Abstract Ribosomes are molecular machineries that decode the information within mRNAs and generate all the proteins required for cellular activities. Ribosomes are essential to every living organism. The synthesis of ribosome is an intricate pro ...
Lassa Virus (LV)Real Time RT-PCR Kit User Manual For In Vitro
... Molecular Grade Water is used for dilution. Dilution is not needed for qualitative real-time PCR detection. Take positive control (1×107copies/ml) as the starting high standard in the first tube. Respectively pipette 36ul Molecular Grade Water into next three tubes. Do three dilutions as the followi ...
... Molecular Grade Water is used for dilution. Dilution is not needed for qualitative real-time PCR detection. Take positive control (1×107copies/ml) as the starting high standard in the first tube. Respectively pipette 36ul Molecular Grade Water into next three tubes. Do three dilutions as the followi ...
Document
... (cf. Introduction), the two possibilities remained that they were fish orthologs of tetrapod TPPP2s or fish specific paralogs (tppp3a) resulted from the fish specific whole genome duplication. The recently published sequencing data of the sea lamprey (Petromyzon marinus) genome [28] may help findin ...
... (cf. Introduction), the two possibilities remained that they were fish orthologs of tetrapod TPPP2s or fish specific paralogs (tppp3a) resulted from the fish specific whole genome duplication. The recently published sequencing data of the sea lamprey (Petromyzon marinus) genome [28] may help findin ...
Facioscapulohumeral Muscular Dystrophy: The Molecular Signaling
... [11], which plays an important role in alternative splicing - binds to exon-intron recognition motifs. Thus, the splicing process is activated, but the accuracy is reduced. This apparently leads to accumulation of abnormal splicing products, which adversely affects the cell cycle. Also FRG1 positive ...
... [11], which plays an important role in alternative splicing - binds to exon-intron recognition motifs. Thus, the splicing process is activated, but the accuracy is reduced. This apparently leads to accumulation of abnormal splicing products, which adversely affects the cell cycle. Also FRG1 positive ...
Slide 1
... – Some antibiotics work better together than alone – Combining 2 or more drugs may be required to prevent the emergence of resistance e.g. tuberculosis – Combinations should not be given when 1 drug would suffice • Antagonistic effects • No ability to adjust 1 drug concentration ...
... – Some antibiotics work better together than alone – Combining 2 or more drugs may be required to prevent the emergence of resistance e.g. tuberculosis – Combinations should not be given when 1 drug would suffice • Antagonistic effects • No ability to adjust 1 drug concentration ...
10c
... Some infectious agents are made only of RNA or protein. – Viroids are small, circular RNA molecules that infect plants. Viroids – replicate within host cells without producing proteins and – interfere with plant growth. ...
... Some infectious agents are made only of RNA or protein. – Viroids are small, circular RNA molecules that infect plants. Viroids – replicate within host cells without producing proteins and – interfere with plant growth. ...
FLPe Expression Plasmids for E. coli
... 4. Increase the temperature to 37°C and incubate the culture for further 2 3 hours. During this step expression of flpe gene is induced. The FLPe recombinase will subsequently recognise the two aligned FRT sites and all DNA in between (including the selectable marker) gets excised. At the same time ...
... 4. Increase the temperature to 37°C and incubate the culture for further 2 3 hours. During this step expression of flpe gene is induced. The FLPe recombinase will subsequently recognise the two aligned FRT sites and all DNA in between (including the selectable marker) gets excised. At the same time ...
1 Supplementary information: Methods: Table S1: Primer Name
... Figure S1 legend. Var1csa and var-CS2 genes are present in FCR3∆var2csa mutants. A. Schematic representation of the var-CS2 gene and the genomic loci for FCR3var1csa and 3D7var1csa. The different Duffy binding-like domains (DBL), the cysteine-rich interdomain regions (CIDR) and the C-terminal cytop ...
... Figure S1 legend. Var1csa and var-CS2 genes are present in FCR3∆var2csa mutants. A. Schematic representation of the var-CS2 gene and the genomic loci for FCR3var1csa and 3D7var1csa. The different Duffy binding-like domains (DBL), the cysteine-rich interdomain regions (CIDR) and the C-terminal cytop ...
Insights from the HuR-interacting transcriptome: ncRNAs, ubiquitin
... Hu antigen R (HuR) protein provides a well-annotated model for the study of RNA binding protein function in signaling pathways and cellular physiology. HuR influences processing, localization, translation, and the stability of mRNAs throughout their lifecycle, making important contributions to a coh ...
... Hu antigen R (HuR) protein provides a well-annotated model for the study of RNA binding protein function in signaling pathways and cellular physiology. HuR influences processing, localization, translation, and the stability of mRNAs throughout their lifecycle, making important contributions to a coh ...
Depolymerization of Heparin/HS | NEB
... Heparin and heparan sulfate (HS) glycosaminoglycans are linear sulfated polysaccharides located on cell-surface membranes and in extracellular matrices in virtually all animal tissues. Heparin and HS have been implicated in cell-biological processes, cell adhesion and regulation of enzymatic catalys ...
... Heparin and heparan sulfate (HS) glycosaminoglycans are linear sulfated polysaccharides located on cell-surface membranes and in extracellular matrices in virtually all animal tissues. Heparin and HS have been implicated in cell-biological processes, cell adhesion and regulation of enzymatic catalys ...
Gene Expression - Bioinformatics and Genomics Department at CIPF
... acctgttgatggcgacagggactgtatgctgatct atgctgatgcatgcatgctgactactgatgtgggg gctattgacttgatgtctatc.... ...
... acctgttgatggcgacagggactgtatgctgatct atgctgatgcatgcatgctgactactgatgtgggg gctattgacttgatgtctatc.... ...
Pre-mRNA splicing: life at the centre of the central dogma
... still await functional characterization. Some of the additional proteins identified in these complexes have known associations with other aspects of RNA processing, including transcription and mRNA export. This is consistent with the intimate coupling of different steps in gene expression. Alternati ...
... still await functional characterization. Some of the additional proteins identified in these complexes have known associations with other aspects of RNA processing, including transcription and mRNA export. This is consistent with the intimate coupling of different steps in gene expression. Alternati ...
cha2
... 1) The size of the positive data set may be increased by incorporating point mutations in non-sensitive positions 2) Negative data sets are generated by several ways i.e. a) Shuffling or randomising the positive data set. This does not destroy the the correlations between the bases completely. b) U ...
... 1) The size of the positive data set may be increased by incorporating point mutations in non-sensitive positions 2) Negative data sets are generated by several ways i.e. a) Shuffling or randomising the positive data set. This does not destroy the the correlations between the bases completely. b) U ...
Organic Chemistry Fifth Edition
... The distribution of the bases adenine (A), guanine (G), thymine (T), and cytosine (C) ...
... The distribution of the bases adenine (A), guanine (G), thymine (T), and cytosine (C) ...
Zygotic Genome Activation During the Maternal-to
... In most animals, the maternal contribution directs a series of synchronized mitoses while maintaining a relatively constant volume as it forms a blastula. Subsequently, coordinated cell movements during gastrulation form distinct germ layers that specify the various tissues in the mature organism. W ...
... In most animals, the maternal contribution directs a series of synchronized mitoses while maintaining a relatively constant volume as it forms a blastula. Subsequently, coordinated cell movements during gastrulation form distinct germ layers that specify the various tissues in the mature organism. W ...
Lecture 2 Nucleic Acid Structure
... G = -RT logK = -1.4 logK kcal/mol (room temp) -1.4 kcal/mol for Product/Substrate = 10 ...
... G = -RT logK = -1.4 logK kcal/mol (room temp) -1.4 kcal/mol for Product/Substrate = 10 ...
07 NucleicAcids-06b
... Origins of Replication Eukaryotic chromosome -- hundreds to thousands Replication proceeds in both directions Replication fork – ends of each replication bubble ...
... Origins of Replication Eukaryotic chromosome -- hundreds to thousands Replication proceeds in both directions Replication fork – ends of each replication bubble ...