REVIEWS
... carbon, nitrogen, phosphorus and sulphur. This enables them to feed the central metabolic pathways — glycolysis, the pentose-phosphate pathway, the citric acid cycle and the 2‑oxoglutarate–glutamate–glutamine cycle — from which all of the precursors that are required for the synthesis of the cell’s ...
... carbon, nitrogen, phosphorus and sulphur. This enables them to feed the central metabolic pathways — glycolysis, the pentose-phosphate pathway, the citric acid cycle and the 2‑oxoglutarate–glutamate–glutamine cycle — from which all of the precursors that are required for the synthesis of the cell’s ...
Genome-wide analysis of the GRAS gene family in
... (Helariutta et al., 2000). Medicago NSP1 functions as a primary transcriptional regulator mediating all known Nod factor-induced transcriptional responses and thus regulating the rhizobium-legume symbiosis (Smit et al., 2005). The function of the SHR-C proteins is as yet unknown. Physic nut has six ...
... (Helariutta et al., 2000). Medicago NSP1 functions as a primary transcriptional regulator mediating all known Nod factor-induced transcriptional responses and thus regulating the rhizobium-legume symbiosis (Smit et al., 2005). The function of the SHR-C proteins is as yet unknown. Physic nut has six ...
EPICENTRE Enzyme Catalog
... Polymerase is covered by one or more of the following US patents and corresponding patent claims outside the US: 5,079,352, 5,789,224, 5,618,711, 6,127,155 and claims outside the US corresponding to US Patent No. 4,889,818. The purchase of this product includes a limited, non-transferable immunity f ...
... Polymerase is covered by one or more of the following US patents and corresponding patent claims outside the US: 5,079,352, 5,789,224, 5,618,711, 6,127,155 and claims outside the US corresponding to US Patent No. 4,889,818. The purchase of this product includes a limited, non-transferable immunity f ...
Control Bacterial Quorum Sensing: Its Role in Virulence and
... agr regulators is that they provide S. aureus the ability to respond to extracellular environmental signals, in addition to AIPs, using the QS circuitry. For example, following extracellular stress, the alternative sigma factor sB interacts with core RNAP to direct transcription of surface proteins ...
... agr regulators is that they provide S. aureus the ability to respond to extracellular environmental signals, in addition to AIPs, using the QS circuitry. For example, following extracellular stress, the alternative sigma factor sB interacts with core RNAP to direct transcription of surface proteins ...
Origin and evolution of peptide-modifying
... epimerases/isomerases (e.g. RmlC, mannose-6-phosphate isomerase and glucose-6-phosphate isomerase; 25). In the literature, there is rampant confusion in the nomenclature of these proteins with different overlapping groups termed cupins, JmjC or 2OGFeDO without a regard for their biochemistry (i.e. de ...
... epimerases/isomerases (e.g. RmlC, mannose-6-phosphate isomerase and glucose-6-phosphate isomerase; 25). In the literature, there is rampant confusion in the nomenclature of these proteins with different overlapping groups termed cupins, JmjC or 2OGFeDO without a regard for their biochemistry (i.e. de ...
Functional ultrastructure of the plant nucleolus
... eukaryotic cells. They not only specialize in the production of ribosomal subunits but also play roles in many fundamental cellular activities. Concerning ribosome biosynthesis, particular stages of this process, i.e., ribosomal DNA transcription, primary RNA transcript processing, and ribosome asse ...
... eukaryotic cells. They not only specialize in the production of ribosomal subunits but also play roles in many fundamental cellular activities. Concerning ribosome biosynthesis, particular stages of this process, i.e., ribosomal DNA transcription, primary RNA transcript processing, and ribosome asse ...
ppt - Chair of Computational Biology
... play a variety of roles in biology. Most notably, siRNA is involved in the RNA interference (RNAi) pathway, where it interferes with the expression of a specific gene. In addition to their role in the RNAi pathway, siRNAs also act in RNAi-related pathways, e.g., as an antiviral mechanism or in shapi ...
... play a variety of roles in biology. Most notably, siRNA is involved in the RNA interference (RNAi) pathway, where it interferes with the expression of a specific gene. In addition to their role in the RNAi pathway, siRNAs also act in RNAi-related pathways, e.g., as an antiviral mechanism or in shapi ...
Protein thermal stability: insights from atomic displacement
... possess better packed interiors than their mesophilic counterparts, leading to lesser overall flexibility and a corresponding reduction in surface-to-volume ratio. These observations prompted an analysis of B values reported in high-resolution X-ray crystal structures of mesophilic and thermophilic ...
... possess better packed interiors than their mesophilic counterparts, leading to lesser overall flexibility and a corresponding reduction in surface-to-volume ratio. These observations prompted an analysis of B values reported in high-resolution X-ray crystal structures of mesophilic and thermophilic ...
Lifestyle in the sperm
... small RNA is inherited and then these molecules re-establish a certain chromatin mark”, he said. This idea is in line with a previous study by Andrew Fire and colleagues who showed that the genomic locus is not required to pass RNAi-induced silencing from parents to offspring; all you need is some d ...
... small RNA is inherited and then these molecules re-establish a certain chromatin mark”, he said. This idea is in line with a previous study by Andrew Fire and colleagues who showed that the genomic locus is not required to pass RNAi-induced silencing from parents to offspring; all you need is some d ...
Regulation of the pyruvate dehydrogenase complex
... functionality becomes evident with emergence of PDHK activity in higher organisms (Figure 1B; see also below). Since PDH is a heterotetramer (α 2 β 2 ), it contains six potential phosphorylation sites. Interestingly, phosphorylation of only one site renders this component inactive because of its hal ...
... functionality becomes evident with emergence of PDHK activity in higher organisms (Figure 1B; see also below). Since PDH is a heterotetramer (α 2 β 2 ), it contains six potential phosphorylation sites. Interestingly, phosphorylation of only one site renders this component inactive because of its hal ...
Cell biology of carbohydrate metabolism
... sterols were determined in wild-type and ChREBP-/- mice ...
... sterols were determined in wild-type and ChREBP-/- mice ...
Mechanisms of Unidirectional Translocation & Unwinding
... Stepping requires at least 2 NA binding sites that independently bind and release NA and change the distance between each other. • Monomeric helicases: 2 hands represent 2 parts of NA binding site that move relative to each other. Both sites are controlled by a single NTPase site. • Oligomeric helic ...
... Stepping requires at least 2 NA binding sites that independently bind and release NA and change the distance between each other. • Monomeric helicases: 2 hands represent 2 parts of NA binding site that move relative to each other. Both sites are controlled by a single NTPase site. • Oligomeric helic ...
4.5 Regulation and Variability of Signaling by Nuclear Receptors
... The crystal structures of the ligand-binding domains of several nuclear receptors have been resolved demonstrating a similar overall structure. Fig. 4.8a shows the receptor for alltrans retinoic acid, RAR, with is bound ligand. The ligand-binding domain is formed from 12 ahelices numbered from H1 to ...
... The crystal structures of the ligand-binding domains of several nuclear receptors have been resolved demonstrating a similar overall structure. Fig. 4.8a shows the receptor for alltrans retinoic acid, RAR, with is bound ligand. The ligand-binding domain is formed from 12 ahelices numbered from H1 to ...
Large-scale analysis of Influenza A virus nucleoprotein sequence
... Conservation analysis The conservation of amino acid residues was obtained and projected onto the protein structure using the ConSurf 2010 server (Ashkenazy et al., 2010; Celniker et al., 2013; Landau et al., 2005). The ConSurf algorithm takes into account the evolutionary relationships between prot ...
... Conservation analysis The conservation of amino acid residues was obtained and projected onto the protein structure using the ConSurf 2010 server (Ashkenazy et al., 2010; Celniker et al., 2013; Landau et al., 2005). The ConSurf algorithm takes into account the evolutionary relationships between prot ...
Infectious Pancreatic Necrosis Virus
... found in farmed Salmonoid fish. The genome of this virus consists of two segments of double-stranded RNA packaged in a non-enveloped icosahedral capsid. The larger segment, A, is 3097 nucleotides long and encodes a 107kDa precursor protein made up of VP2, VP3 and VP4 from a single large open reading ...
... found in farmed Salmonoid fish. The genome of this virus consists of two segments of double-stranded RNA packaged in a non-enveloped icosahedral capsid. The larger segment, A, is 3097 nucleotides long and encodes a 107kDa precursor protein made up of VP2, VP3 and VP4 from a single large open reading ...
Onset of lactation in the bovine mammary gland:
... biological-process categories and provides a z score for each category to represent a statistical measure of the relative amounts of gene expression changes in the given GO term. This approach revealed that the major changes of gene expression at the two stages were associated with the cellular (~40 ...
... biological-process categories and provides a z score for each category to represent a statistical measure of the relative amounts of gene expression changes in the given GO term. This approach revealed that the major changes of gene expression at the two stages were associated with the cellular (~40 ...
Differential expression of vasa homologue gene in the germ cells
... seen only when testis and ovary RNAs were used. No ampli®ed products were detected in either brain, spleen, liver, heart or kidney (data not shown). In situ hybridization was used to determine the pattern of tilapia vas expression in germ cells during gonadogenesis and gametogenesis of both sexes (f ...
... seen only when testis and ovary RNAs were used. No ampli®ed products were detected in either brain, spleen, liver, heart or kidney (data not shown). In situ hybridization was used to determine the pattern of tilapia vas expression in germ cells during gonadogenesis and gametogenesis of both sexes (f ...
A novel EVI1 gene family, MEL1, lacking a PR domain (MEL1S) is
... a member of the EVI1 gene family and also as a PR domain member (PRDM16).23 MEL1 was found in t(1;3)(p36;q21)positive AML, which has similar clinicopathological features to 3q21q26 syndrome, as a transcriptionally activated gene near the chromosomal breakpoint. The structure of the MEL1 gene product ...
... a member of the EVI1 gene family and also as a PR domain member (PRDM16).23 MEL1 was found in t(1;3)(p36;q21)positive AML, which has similar clinicopathological features to 3q21q26 syndrome, as a transcriptionally activated gene near the chromosomal breakpoint. The structure of the MEL1 gene product ...
Patterns of prokaryotic lateral gene transfers affecting parasitic
... ’TMDs ≥ 4’ or ‘TMDs 1-3’ refers to the number of TMDs predicted on protein sequences. Transporters typically have at least four TMDs (TMDs ≥ 4). Proteins with one to three TMDs represent putative membrane proteins. d EC numbers were annotated for each entry based on a significant sequence similarity ...
... ’TMDs ≥ 4’ or ‘TMDs 1-3’ refers to the number of TMDs predicted on protein sequences. Transporters typically have at least four TMDs (TMDs ≥ 4). Proteins with one to three TMDs represent putative membrane proteins. d EC numbers were annotated for each entry based on a significant sequence similarity ...
Patterns of prokaryotic lateral gene transfers affecting parasitic
... ’TMDs ≥ 4’ or ‘TMDs 1-3’ refers to the number of TMDs predicted on protein sequences. Transporters typically have at least four TMDs (TMDs ≥ 4). Proteins with one to three TMDs represent putative membrane proteins. d EC numbers were annotated for each entry based on a significant sequence similarity ...
... ’TMDs ≥ 4’ or ‘TMDs 1-3’ refers to the number of TMDs predicted on protein sequences. Transporters typically have at least four TMDs (TMDs ≥ 4). Proteins with one to three TMDs represent putative membrane proteins. d EC numbers were annotated for each entry based on a significant sequence similarity ...
tRNA Core Hypothesis for the Transition from the RNA World to the
... cycles. At this stage, the structural information emerged and was involved in the direct replication by complementarity between nucleotides. Amino acids in prebiotic conditions were abundant, but their incorporation to primitive forms of life should have been dependent on the chemical interaction wi ...
... cycles. At this stage, the structural information emerged and was involved in the direct replication by complementarity between nucleotides. Amino acids in prebiotic conditions were abundant, but their incorporation to primitive forms of life should have been dependent on the chemical interaction wi ...
Protein synthesis 2 - Pima Community College : Directories
... 10.8 The genetic code is the Rosetta stone of life – Characteristics of the genetic code – Triplet: Three nucleotides specify one amino acid – 61 codons correspond to amino acids – AUG codes for methionine and signals the start of transcription – 3 “stop” codons signal the end of translation ...
... 10.8 The genetic code is the Rosetta stone of life – Characteristics of the genetic code – Triplet: Three nucleotides specify one amino acid – 61 codons correspond to amino acids – AUG codes for methionine and signals the start of transcription – 3 “stop” codons signal the end of translation ...
Darnell, JC, Warren, ST and Darnell, RB: The fragile X mental retardation protein, FMRP, recognizes G-quartets. Mental Retardation and Developmental Disabilities Research Reviews 10:49-52 (2004).
... X patients who express no FMRP) would provide an important measure of their likelihood as legitimate FMRP target RNAs. In fact, analysis of polysomes prepared from the above cell lines led to the finding that 10 of 13 candidate FMRP RNA targets showed alteration in their polysome distribution in the ...
... X patients who express no FMRP) would provide an important measure of their likelihood as legitimate FMRP target RNAs. In fact, analysis of polysomes prepared from the above cell lines led to the finding that 10 of 13 candidate FMRP RNA targets showed alteration in their polysome distribution in the ...
GT-B fold
... Novel folds are expected for GTs that use a lipid-phosphate donor Virtually nothing is known about the structures and mechanisms of these large membrane-embedded GTs. The successful crystallization of PglB now opens new avenues to fill the gap. ...
... Novel folds are expected for GTs that use a lipid-phosphate donor Virtually nothing is known about the structures and mechanisms of these large membrane-embedded GTs. The successful crystallization of PglB now opens new avenues to fill the gap. ...
JNK1 plays an important part in this process provides an
... (Figure 1, broken gray oval and line). Indeed, mutation of two conserved basic and surface-exposed amino acids in the catalytic domain abolishes binding between archaeal H/ACA RNA and the Cbf5–Nop10 dimer [5]. Moreover, the PUA domain is essential for RNP assembly and activity because (in the presen ...
... (Figure 1, broken gray oval and line). Indeed, mutation of two conserved basic and surface-exposed amino acids in the catalytic domain abolishes binding between archaeal H/ACA RNA and the Cbf5–Nop10 dimer [5]. Moreover, the PUA domain is essential for RNP assembly and activity because (in the presen ...