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Slide 1 - SCHOOLinSITES
Slide 1 - SCHOOLinSITES

... 3.5.2 Outline DNA transcription in terms of the formation of an RNA strand complementary to the DNA strand by RNA polymerase 3.5.3 Describe the genetic code in terms of codons composed of triplets of bases 3.5.4 Explain the process of translation, leading to polypeptide formation 3.5.5 Discuss the r ...
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No Slide Title

... The forward rate constant for RNA Pol binding to promoters is faster than random diffusion (that limits the constant to 108/M-1Sec-1). The measured rate constant for association with a 60 bp target is 1014/M-1Sec-1. If the target is the whole genome the rate constant is around 1014/M-1Sec-1. But how ...
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... Uses property that transcription factors generally have separable transcriptional activation (AD) and DNA binding (DBD) domains. A functional transcription factor can be created if a separately expressed AD can be made to interact with a DBD. ...
Review - Jefferson Township Public Schools
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...  DNA opens up and messenger RNA (mRNA) copies message  mRNA is edited – some parts taken out (introns)  mRNA goes out of nucleus to ribosome  mRNA attaches to ribosome  Transfer RNA (tRNA) picks up an amino acid  tRNA attaches to mRNA matching complementary base pairs at opposite end from amin ...
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... In the genetic code, nucleotide triplets specify amino acids • In the __________, three consecutive bases specify an amino acid, creating 43 (64) possible ________. • The genetic instructions for a polypeptide chain are written in DNA as a series of three__________words. ...
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... (1) It's sequence will be identical (not complimentary) to the RNA molecule synthesized from the coding strand (a) Except Ts replace Us b) The coding strand sequence is given when talking about double stranded DNA (1) Same polarity as RNA (2) Easier when referring to the genetic code (3) Always give ...
Medical and Molecular Genetics
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... regulate transcription. Chromatin must decondense in order for the replication machinery and transcriptional machinery to gain access to the DNA. The dynamic restructuring of chromatin is carried out by multiprotein complexes that are called chromatin remodeling factors. 3) List and state the functi ...
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Bio 112 17 sp11
Bio 112 17 sp11

... 11. Define and explain the role of ribozymes. What three properties allow some RNA molecules to function as ribozymes? 12. Describe the functional and evolutionary significance of introns. 13. Explain why, due to alternative RNA splicing, the number of different protein products an organism can prod ...
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Transcriptional regulation

In molecular biology and genetics, transcriptional regulation is the means by which a cell regulates the conversion of DNA to RNA (transcription), thereby orchestrating gene activity. A single gene can be regulated in a range of ways, from altering the number of copies of RNA that are transcribed, to the temporal control of when the gene is transcribed. This control allows the cell or organism to respond to a variety of intra- and extracellular signals and thus mount a response. Some examples of this include producing the mRNA that encode enzymes to adapt to a change in a food source, producing the gene products involved in cell cycle specific activities, and producing the gene products responsible for cellular differentiation in higher eukaryotes.The regulation of transcription is a vital process in all living organisms. It is orchestrated by transcription factors and other proteins working in concert to finely tune the amount of RNA being produced through a variety of mechanisms. Prokaryotic organisms and eukaryotic organisms have very different strategies of accomplishing control over transcription, but some important features remain conserved between the two. Most importantly is the idea of combinatorial control, which is that any given gene is likely controlled by a specific combination of factors to control transcription. In a hypothetical example, the factors A and B might regulate a distinct set of genes from the combination of factors A and C. This combinatorial nature extends to complexes of far more than two proteins, and allows a very small subset (less than 10%) of the genome to control the transcriptional program of the entire cell.
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