Poly(ethylene glycol)-supported a,a,a
... in what is known as organocatalysis is a rapidly expanding field of research.1 Some of the most useful such compounds for this type of catalysis are amines, such as amino acids and their derivatives2,3 and naturally occurring alkaloids.4 These catalysts have been found to be effective in Baylis–Hillma ...
... in what is known as organocatalysis is a rapidly expanding field of research.1 Some of the most useful such compounds for this type of catalysis are amines, such as amino acids and their derivatives2,3 and naturally occurring alkaloids.4 These catalysts have been found to be effective in Baylis–Hillma ...
CH402 Asymmetric catalytic reactions Prof M. Wills
... Asymmetric catalysis – Enolate alkylation The reaction proceeds via a complex in which the catalyst and the enolate are bound by a hydrogen bond (at least, that's the theory): Cl ...
... Asymmetric catalysis – Enolate alkylation The reaction proceeds via a complex in which the catalyst and the enolate are bound by a hydrogen bond (at least, that's the theory): Cl ...
Reactions Homework Packet
... no reaction, write NO REACTION. For the following assume all compounds are aqueous (dissolved in water). ...
... no reaction, write NO REACTION. For the following assume all compounds are aqueous (dissolved in water). ...
CBS Reduction
... History of CBS reduction and selectivity • In 1981 Itsuno et al reduced achiral ketones to chiral alcohols using alkoxy-amine-borane complexes in enantioselectivity and in high yield. • In 1987 E.J. Corey, with his co-workers, used oxazaborolidines to rapidlly reduce ketones in the presence of BH3- ...
... History of CBS reduction and selectivity • In 1981 Itsuno et al reduced achiral ketones to chiral alcohols using alkoxy-amine-borane complexes in enantioselectivity and in high yield. • In 1987 E.J. Corey, with his co-workers, used oxazaborolidines to rapidlly reduce ketones in the presence of BH3- ...
Ethers, Sulfides, Epoxides
... as protecting groups for alcohols. Recall that the key step in forming the acetal was creating the carbocation as shown… There are other ways to create carbocations…… ...
... as protecting groups for alcohols. Recall that the key step in forming the acetal was creating the carbocation as shown… There are other ways to create carbocations…… ...
Chemistry 3719L – Week 9 Reduction of Benzil with Sodium
... Pages 87-92 – review melting points ...
... Pages 87-92 – review melting points ...
Lecture 17-edited
... Hydrognation of carbonyls of aldehydes, ketones and esters have been well developed with chiral metal complexes in the presence of molecular hydrogen. For example, rhodium complexes with molecular hydrogen have shown good catalytic activity towards to the reduction of ketonic substrates possessing n ...
... Hydrognation of carbonyls of aldehydes, ketones and esters have been well developed with chiral metal complexes in the presence of molecular hydrogen. For example, rhodium complexes with molecular hydrogen have shown good catalytic activity towards to the reduction of ketonic substrates possessing n ...
Topic 10 IB Chemistry Definitions
... hydroxyl group). Can be oxidized to aldehydes (by loss of hydrogens) and then to carboxylic acids (by gain of oxygen). Ethanol can be oxidized to ethanal by the orange Cr2O72- ion, which itself becomes reduced to the green Cr3+ ion. ...
... hydroxyl group). Can be oxidized to aldehydes (by loss of hydrogens) and then to carboxylic acids (by gain of oxygen). Ethanol can be oxidized to ethanal by the orange Cr2O72- ion, which itself becomes reduced to the green Cr3+ ion. ...
Ring-closing metathesis
Ring-closing metathesis, or RCM, is a widely used variation of olefin metathesis in organic chemistry for the synthesis of various unsaturated rings via the intramolecular metathesis of two terminal alkenes, which forms the cycloalkene as the E- or Z- isomers and volatile ethylene.The most commonly synthesized ring sizes are between 5-7 atoms; however, reported syntheses include 45- up to 90- membered macroheterocycles. These reactions are metal-catalyzed and proceed through a metallacyclobutane intermediate. It was first published by Dider Villemin in 1980 describing the synthesis of an Exaltolide precursor, and later become popularized by Robert H. Grubbs and Richard R. Schrock, who shared the Nobel Prize in Chemistry, along with Yves Chauvin, in 2005 for their combined work in olefin metathesis. RCM is a favorite among organic chemists due to its synthetic utility in the formation of rings, which were previously difficult to access efficiently, and broad substrate scope. Since the only major by-product is ethylene, these reactions may also be considered atom economic, an increasingly important concern in the development of green chemistry.There are several reviews published on ring-closing metathesis.