Reactions of amino acids - Katedra i Zakład Chemii
... When the diluted solution of copper (II) sulphate and some drops of strong base solution are added to the solution of a protein or a peptide, the violet colour appears. This reaction occurs only if the peptide molecule contains at least two peptide bonds (3 amino acids). Free amino acids and dipepti ...
... When the diluted solution of copper (II) sulphate and some drops of strong base solution are added to the solution of a protein or a peptide, the violet colour appears. This reaction occurs only if the peptide molecule contains at least two peptide bonds (3 amino acids). Free amino acids and dipepti ...
REVISED syllabus for CHEM F494 - Asymmetric Organic Synthesis
... The Office of Disability Services implements the Americans with Disabilities Act (ADA), and insures that UAF students have equal access to the campus and course materials. Students with documented disabilities who may need reasonable academic accommodations should discuss these with the instructor d ...
... The Office of Disability Services implements the Americans with Disabilities Act (ADA), and insures that UAF students have equal access to the campus and course materials. Students with documented disabilities who may need reasonable academic accommodations should discuss these with the instructor d ...
Notes 07 Organometallic Compounds with notes
... R2CuLi + R’-X R-R’ + RCu + LiX Reaction Type: Nucleophilic Substitution. Creation of new C-C bonds. 1 alkyl iodides are best, otherwise an elimination reaction can occur. The R’ group in the halide can be aryl or vinyl. The R group of the cuprate can be aryl or vinyl. Although the mechanism looks ...
... R2CuLi + R’-X R-R’ + RCu + LiX Reaction Type: Nucleophilic Substitution. Creation of new C-C bonds. 1 alkyl iodides are best, otherwise an elimination reaction can occur. The R’ group in the halide can be aryl or vinyl. The R group of the cuprate can be aryl or vinyl. Although the mechanism looks ...
Chemistry - CBSE Academic
... mankind with serious waste disposal problem as these materials do not disintegrate by themselves. In view of this, certain polymers are being developed which are broken down rapidly by microorganisms. Shalini feels relaxed that such kinds of biomaterials are being developed. (a) Name the class of th ...
... mankind with serious waste disposal problem as these materials do not disintegrate by themselves. In view of this, certain polymers are being developed which are broken down rapidly by microorganisms. Shalini feels relaxed that such kinds of biomaterials are being developed. (a) Name the class of th ...
1. All the questions are compulsory. 2. Q. N
... Use of calculators is not allowed, use log tables wherever required. 1. Name the non stoichiometric point defect responsible for colour in alkali metal halides. 2. What is shape selective catalysis? 3. Amongst the isomeric alkanes of molecular formula C5H12, identify the one that on photochemical ch ...
... Use of calculators is not allowed, use log tables wherever required. 1. Name the non stoichiometric point defect responsible for colour in alkali metal halides. 2. What is shape selective catalysis? 3. Amongst the isomeric alkanes of molecular formula C5H12, identify the one that on photochemical ch ...
Carboxylic Acids and Their Derivatives
... Factors controlling reactions of acid derivatives: 1) Basicity of nucleophile: Equilibrium favors replacement when incoming nucleophile is more basic than Y:2) Leaving group: Reaction occurs more readily when Y:- is a good leaving group (Weaker base = better leaving group) When Y group is a weak bas ...
... Factors controlling reactions of acid derivatives: 1) Basicity of nucleophile: Equilibrium favors replacement when incoming nucleophile is more basic than Y:2) Leaving group: Reaction occurs more readily when Y:- is a good leaving group (Weaker base = better leaving group) When Y group is a weak bas ...
Problem Set Chapter 13 Solutions February 28, 2013 13.27 Draw
... 13.48 Acid-catalyzed dehydration of 2,2-dimethylcyclohexanol yields a mixture of 1,2dimethylcyclohexene and isopropylidene cyclopentane. Propose a mechanism to account for the formation of both products. OH H+ ...
... 13.48 Acid-catalyzed dehydration of 2,2-dimethylcyclohexanol yields a mixture of 1,2dimethylcyclohexene and isopropylidene cyclopentane. Propose a mechanism to account for the formation of both products. OH H+ ...
Amino Acids - The Exam Formula
... Another exam favourite is going backwards from the amide to the amino acids, which is known as hydrolysis i.e. adding water to the amide to split it up. This is just the reverse of ...
... Another exam favourite is going backwards from the amide to the amino acids, which is known as hydrolysis i.e. adding water to the amide to split it up. This is just the reverse of ...
A. Acid Halides
... The weaker the basicity of the substituent attached to the acyl group, the less the carboxylic acid derivative is stabilized by electron delocalization, the more reactive it will be. Weak bases are easier to eliminate (good leaving groups). ...
... The weaker the basicity of the substituent attached to the acyl group, the less the carboxylic acid derivative is stabilized by electron delocalization, the more reactive it will be. Weak bases are easier to eliminate (good leaving groups). ...
Enzymatic synthesis of sialic acid derivative by immobilized lipase
... catalyzed by Novozym 435. Higher activity of Novozym 435 was also found in the kinetic resolution of secondary alcohols in monoether-functionalized ionic liquids (Zhou et al., 2011). Thus, Novozym 435 was observed to efficiently catalyze the esterification of N-acetyl neuraminic acid methyl ester with ...
... catalyzed by Novozym 435. Higher activity of Novozym 435 was also found in the kinetic resolution of secondary alcohols in monoether-functionalized ionic liquids (Zhou et al., 2011). Thus, Novozym 435 was observed to efficiently catalyze the esterification of N-acetyl neuraminic acid methyl ester with ...
Protein is a polymer of amino acids
... Amino acids are joined together when a dehydration reaction removes a hydroxyl group from the carboxyl end of one amino acid and a hydrogen from the amino group of another. The resulting covalent bond is called a peptide bond. ...
... Amino acids are joined together when a dehydration reaction removes a hydroxyl group from the carboxyl end of one amino acid and a hydrogen from the amino group of another. The resulting covalent bond is called a peptide bond. ...
Chapter 24. Amines
... • We would expect that the more highly substituted alkene product predominates in the E2 reaction of an alkyl halide (Zaitsev's rule) • However, the less highly substituted alkene predominates in the Hofmann elimination due to the large size of the trialkylamine leaving group • The base must abstrac ...
... • We would expect that the more highly substituted alkene product predominates in the E2 reaction of an alkyl halide (Zaitsev's rule) • However, the less highly substituted alkene predominates in the Hofmann elimination due to the large size of the trialkylamine leaving group • The base must abstrac ...
Chapter 24. Amines
... • We would expect that the more highly substituted alkene product predominates in the E2 reaction of an alkyl halide (Zaitsev's rule) • However, the less highly substituted alkene predominates in the Hofmann elimination due to the large size of the trialkylamine leaving group • The base must abstrac ...
... • We would expect that the more highly substituted alkene product predominates in the E2 reaction of an alkyl halide (Zaitsev's rule) • However, the less highly substituted alkene predominates in the Hofmann elimination due to the large size of the trialkylamine leaving group • The base must abstrac ...
carboxylic acids
... • Carboxylic acids have significantly higher boiling points than their corresponding alcohols or alkanes. ...
... • Carboxylic acids have significantly higher boiling points than their corresponding alcohols or alkanes. ...
11. Reactions of Alkyl Halides
... weaker interactions with substrate and permit faster reaction ...
... weaker interactions with substrate and permit faster reaction ...
Carbohydrates important reactions
... an aldonic acid. Because of the 2º hydroxyl functions that are also present in these compounds, a mild oxidizing agent such as hypobromite must be used for this conversion (equation 1). If both ends of an aldose chain are oxidized to carboxylic acids the product is called an aldaric acid. By convert ...
... an aldonic acid. Because of the 2º hydroxyl functions that are also present in these compounds, a mild oxidizing agent such as hypobromite must be used for this conversion (equation 1). If both ends of an aldose chain are oxidized to carboxylic acids the product is called an aldaric acid. By convert ...
Microsoft Word - Final Exam Study Guide
... B. Label the structure with any missing formal charges. C. Draw at least two more resonance structures and rank them from most major contributor to most minor contributor. D. Mark all the chiral centers and label any designated chiral centers R or S. B. Would you expect the elimination of cis-1-t-bu ...
... B. Label the structure with any missing formal charges. C. Draw at least two more resonance structures and rank them from most major contributor to most minor contributor. D. Mark all the chiral centers and label any designated chiral centers R or S. B. Would you expect the elimination of cis-1-t-bu ...
Formose reaction controlled by boronic acid - Beilstein
... Figure 3 compares 1H and 13C NMR spectra for the products obtained in the presence of SPB and pVPB/NaSS. The 1H and 13C NMR spectra for SPB exhibit broad signals, similar to those for a formose reaction without boronic acid compounds. Since it was difficult to remove SPB from the reaction mixture, t ...
... Figure 3 compares 1H and 13C NMR spectra for the products obtained in the presence of SPB and pVPB/NaSS. The 1H and 13C NMR spectra for SPB exhibit broad signals, similar to those for a formose reaction without boronic acid compounds. Since it was difficult to remove SPB from the reaction mixture, t ...
Petasis reaction
The Petasis reaction (alternatively called the Petasis borono–Mannich (PBM) reaction) is the chemical reaction of an amine, aldehyde, and vinyl- or aryl-boronic acid to form substituted amines.Reported in 1993 by Nicos Petasis as a practical method towards the synthesis of a geometrically pure antifungal agent, naftifine, the Petasis reaction can be described as a variation of the Mannich reaction. Rather than generating an enolate to form the substituted amine product, in the Petasis reaction, the vinyl group of the organoboronic acid serves as the nucleophile. In comparison to other methods of generating allyl amines, the Petasis reaction tolerates a multifunctional scaffold, with a variety of amines and organoboronic acids as potential starting materials. Additionally, the reaction does not require anhydrous or inert conditions. As a mild, selective synthesis, the Petasis reaction is useful in generating α-amino acids, and is utilized in combinatorial chemistry and drug discovery.