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2009_outline_4

... c. Lactone formation C. Reactions at Carbonyl Carbon 1. Acidic Hydrolysis - Acyl - Oxygen and Alkyl - Oxygen Cleavage 2. Alkaline Hydrolysis - Acyl - Oxygen Cleavage 3. Transesterification with Alcohols 4. Ammonolysis to Amide and Alcohol 5. Reduction to Alcohols 6. Grignard Reaction D. Reactions at ...
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اســـم المـــدرس: د
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... 2) Write the chemical and the reaction mechanism for the reaction of benzaldehyde with excess methanol and acid catalyst. ...
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Word document format

... 1. Know how to prepare a functional group and what can be made from a functional group. For example, know how to prepare alkenes and what can be made from an alkene. The best way to memorize these reactions is to make flashcards. Include stereospecificity of reaction, where needed. This is most like ...
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Ene reaction



The ene reaction (also known as the Alder-ene reaction) is a chemical reaction between an alkene with an allylic hydrogen (the ene) and a compound containing a multiple bond (the enophile), in order to form a new σ-bond with migration of the ene double bond and 1,5 hydrogen shift. The product is a substituted alkene with the double bond shifted to the allylic position.This transformation is a group transfer pericyclic reaction, and therefore, usually requires highly activated substrates and/or high temperatures. Nonetheless, the reaction is compatible with a wide variety of functional groups that can be appended to the ene and enophile moieties. Also,many useful Lewis acid-catalyzed ene reactions have been developed which can afford high yields and selectivities at significantly lower temperatures, making the ene reaction a useful C–C forming tool for the synthesis of complex molecules and natural products.
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