Search Department of Pediatrics, Harvard Medical School The
... is important in the release of Ca2+ from intracellular stores (24), has also been hypothesized to move through gap junctions and play a role in intracellular calcium wave activation and intercellular calcium wave propagation (25). Sequential intercellular propagation of calcium waves may occur as a ...
... is important in the release of Ca2+ from intracellular stores (24), has also been hypothesized to move through gap junctions and play a role in intracellular calcium wave activation and intercellular calcium wave propagation (25). Sequential intercellular propagation of calcium waves may occur as a ...
Cortical cfos Expression Reveals Broad Receptive Field Excitatory
... airpuff stimulation of the contralateral whisker pad (Figure 3). We observed low overall rates of airpuff-induced firing, and only a few spikes were ever observed at short latency (<50 ms). However, whisker airpuff induced a prolonged depolarization in all cells, with low numbers of spikes distribut ...
... airpuff stimulation of the contralateral whisker pad (Figure 3). We observed low overall rates of airpuff-induced firing, and only a few spikes were ever observed at short latency (<50 ms). However, whisker airpuff induced a prolonged depolarization in all cells, with low numbers of spikes distribut ...
Elective Psych Final Review ~ 2014 Name: Directions: It would, of
... In Pavlov's classic studies on classical conditioning, the conditioned stimulus (CS) was In Pavlov's classic studies on classical conditioning, the conditioned response (CR) was Watson and Rayner's (1920) research using Little Albert was important for showing that… In the Little Albert studi ...
... In Pavlov's classic studies on classical conditioning, the conditioned stimulus (CS) was In Pavlov's classic studies on classical conditioning, the conditioned response (CR) was Watson and Rayner's (1920) research using Little Albert was important for showing that… In the Little Albert studi ...
Rich-club organization in effective connectivity among cortical neurons
... were killed after the recording session; and brain tissue was sectioned, immunostained for NeuN, and imaged to verify the silicon prong placement. Signals from all recording sites were simultaneously sampled at 25 kHz. Spike sorting was performed off-line using a semi-automated Matlab script. The da ...
... were killed after the recording session; and brain tissue was sectioned, immunostained for NeuN, and imaged to verify the silicon prong placement. Signals from all recording sites were simultaneously sampled at 25 kHz. Spike sorting was performed off-line using a semi-automated Matlab script. The da ...
PDF file - Izhikevich
... neurons, each making thousands of synaptic contacts with its neighbors. Given the complexity of the connectivity inherent in cortical anatomy, efforts to describe the pattern of electrical activity in exact detail within even a highly localized population of cortical neurons would be extremely diffi ...
... neurons, each making thousands of synaptic contacts with its neighbors. Given the complexity of the connectivity inherent in cortical anatomy, efforts to describe the pattern of electrical activity in exact detail within even a highly localized population of cortical neurons would be extremely diffi ...
A neurocomputational model of the mammalian fear
... their functions [37]. It is a particularly interesting case study because of how well linked it is to learning and memory; fearful experiences have a strong effect on an animal’s future behaviour [37]. This link provides a potential avenue of investigation into how low-level reward and punishment sys ...
... their functions [37]. It is a particularly interesting case study because of how well linked it is to learning and memory; fearful experiences have a strong effect on an animal’s future behaviour [37]. This link provides a potential avenue of investigation into how low-level reward and punishment sys ...
On the Role of the Pontine Brainstem in Vocal Pattern Generation: A
... pair of electrodes was implanted at a new position. Neuronal activity was recorded during all call types uttered. Quantitative data analysis was done for two highly frequency-modulated call types with a rhythmical character (trill, cackle), a high-pitched (peep), and a low-pitched nonrhythmic call ( ...
... pair of electrodes was implanted at a new position. Neuronal activity was recorded during all call types uttered. Quantitative data analysis was done for two highly frequency-modulated call types with a rhythmical character (trill, cackle), a high-pitched (peep), and a low-pitched nonrhythmic call ( ...
Serotonin synthesis, release and reuptake in terminals: a
... mechanism and function on four different levels, genomic, biochemical, electrophysiological, and behavioral, but changes on each level affect function on the other three levels, and this makes the interpretation of experimental and clinical results very difficult. In addition, the brain is not fixed ...
... mechanism and function on four different levels, genomic, biochemical, electrophysiological, and behavioral, but changes on each level affect function on the other three levels, and this makes the interpretation of experimental and clinical results very difficult. In addition, the brain is not fixed ...
A Comprehensive Protocol for Manual Segmentation of the Medial
... up interest of future research in adopting manual segmentation, either as a primary method of MTL tracing or as a supplementary method to automatic segmentation. By providing an accurate, intuitive, and convenient guide for understanding the MTL anatomy, this protocol will help researchers identify ...
... up interest of future research in adopting manual segmentation, either as a primary method of MTL tracing or as a supplementary method to automatic segmentation. By providing an accurate, intuitive, and convenient guide for understanding the MTL anatomy, this protocol will help researchers identify ...
Measurement of variability dynamics in cortical spike trains
... performed with the help of Mathematica (Wolfram Research, Inc.). We provide documented Matlab code for some of the methods described below within the framework of the FIND toolbox (Meier et al., 2007; http://find.bccn.uni-freiburg.de). 2.1.3. Operational time and rate modulation Neurons observed in ...
... performed with the help of Mathematica (Wolfram Research, Inc.). We provide documented Matlab code for some of the methods described below within the framework of the FIND toolbox (Meier et al., 2007; http://find.bccn.uni-freiburg.de). 2.1.3. Operational time and rate modulation Neurons observed in ...
self-organising map
... neuron in the lattice corresponds to a particular domain or feature of the input patterns. variations in the statistics of the input distribution: regions in the input space H from which sample vectors CS 476: Networks of Neural Computation, CSD, UOC, 2009 ...
... neuron in the lattice corresponds to a particular domain or feature of the input patterns. variations in the statistics of the input distribution: regions in the input space H from which sample vectors CS 476: Networks of Neural Computation, CSD, UOC, 2009 ...
Coordinated Optimization of Visual Cortical Maps
... perturbative treatment, however, gives no information on the speed with which singularities will crystallize into highly ordered arrays. It is conceivable that this process may occur on very long timescales. If this was the case, developmental optimization may lead to long-lived spatially irregular ...
... perturbative treatment, however, gives no information on the speed with which singularities will crystallize into highly ordered arrays. It is conceivable that this process may occur on very long timescales. If this was the case, developmental optimization may lead to long-lived spatially irregular ...
Free recall and recognition in a network model of the... simulating effects of scopolamine on human memory function
... Cholinergic agonists such as carbachol have been shown to enhance long-term potentiation within the dentate gyrus [65], region CA1 [66] and other cortical structures such as the piriform cortex [67], primary visual cortex [68], and somatosensory cortex [69]. Scopolamine may selectively impair learni ...
... Cholinergic agonists such as carbachol have been shown to enhance long-term potentiation within the dentate gyrus [65], region CA1 [66] and other cortical structures such as the piriform cortex [67], primary visual cortex [68], and somatosensory cortex [69]. Scopolamine may selectively impair learni ...
Thalamocortidal Axons Extend Along a Chondroitin Sulfate
... is usually evident in sections at a given embryonic age, depending on the location within the telencephalic wall. Ventricular zone and preplate stages Prior to preplate formation (ElO), intracortical or ventricular placements of DiI demonstrate the radially oriented neuroepithelial cells that span t ...
... is usually evident in sections at a given embryonic age, depending on the location within the telencephalic wall. Ventricular zone and preplate stages Prior to preplate formation (ElO), intracortical or ventricular placements of DiI demonstrate the radially oriented neuroepithelial cells that span t ...
Neuron
... in the PPC. We used analogs of the Wisconsin Card Sorting Test (WCST) (Nakahara et al., 2002), which was originally devised for humans (Anderson et al., 1991; Milner, 1963), and then modified it for monkey lesion studies (Dias et al., 1996, 1997; Passingham, 1972) to test cognitive flexibility; the ...
... in the PPC. We used analogs of the Wisconsin Card Sorting Test (WCST) (Nakahara et al., 2002), which was originally devised for humans (Anderson et al., 1991; Milner, 1963), and then modified it for monkey lesion studies (Dias et al., 1996, 1997; Passingham, 1972) to test cognitive flexibility; the ...
kwanPNAS08
... transgenic mice (VISTA Enhancer Browser) (Fig. S3A–C) (18). Furthermore, the orthologous mouse sequence exhibited activity in deep-layer neurons similar to endogenous Fezf2 expression (Fig. S3D). These results, although not definitive, suggest that this enhancer regulates Fezf2 transcription. Analys ...
... transgenic mice (VISTA Enhancer Browser) (Fig. S3A–C) (18). Furthermore, the orthologous mouse sequence exhibited activity in deep-layer neurons similar to endogenous Fezf2 expression (Fig. S3D). These results, although not definitive, suggest that this enhancer regulates Fezf2 transcription. Analys ...
Neural Activity in Macaque Parietal Cortex Reflects
... responses of LIP neurons reflected substantial temporal integration. Brief pulses had persistent effects on both the monkeys’ choices and the responses of neurons in LIP, lasting up to 800 ms after appearance. These results demonstrate that LIP is involved in neural time integration underlying the a ...
... responses of LIP neurons reflected substantial temporal integration. Brief pulses had persistent effects on both the monkeys’ choices and the responses of neurons in LIP, lasting up to 800 ms after appearance. These results demonstrate that LIP is involved in neural time integration underlying the a ...
The neural correlates of implicit and explicit sequence learning
... cerebral blood flow (rCBF) in the anterior cingulate/medial prefrontal cortex (ACC/MPFC) region specifically correlates with performance scores thought to reflect the conscious control of sequence knowledge in a generation task administered after the end of SRT practice (Destrebecqz et al. 2003). Th ...
... cerebral blood flow (rCBF) in the anterior cingulate/medial prefrontal cortex (ACC/MPFC) region specifically correlates with performance scores thought to reflect the conscious control of sequence knowledge in a generation task administered after the end of SRT practice (Destrebecqz et al. 2003). Th ...
Differential Temporal Storage Capacity in the Baseline Activity of
... analyzed in this study. To ensure that there were sufficient spike data for the analysis of baseline activity, we selected only neurons in which the mean activity during the 1,000-ms interval before array presentation was ⬎3 spikes/s. Note that this threshold level was not essential to observe our m ...
... analyzed in this study. To ensure that there were sufficient spike data for the analysis of baseline activity, we selected only neurons in which the mean activity during the 1,000-ms interval before array presentation was ⬎3 spikes/s. Note that this threshold level was not essential to observe our m ...
Affective percept and voluntary action: A hypothesis
... systems. Accordingly, we will distinguish food affective stimuli, esthetic affective stimuli, etc. Different affective stimuli evoke the corresponding affective percepts and the latter can be divided according to the same four criteria. The division of affective percepts according to criteria 1 and ...
... systems. Accordingly, we will distinguish food affective stimuli, esthetic affective stimuli, etc. Different affective stimuli evoke the corresponding affective percepts and the latter can be divided according to the same four criteria. The division of affective percepts according to criteria 1 and ...
gross_neuroanatomy-1
... surface of the brain. Unlike other sulci that delineate lobes, TO is much more variable between individuals and it is not easy to identify • The functional overlap between posterior temporal and occipital cortices is also reflected by the lack of one or more sulci that divide the temporal from the ...
... surface of the brain. Unlike other sulci that delineate lobes, TO is much more variable between individuals and it is not easy to identify • The functional overlap between posterior temporal and occipital cortices is also reflected by the lack of one or more sulci that divide the temporal from the ...
Complete Pattern of Ocular Dominance Columns in Human Primary
... Key words: cytochrome oxidase; cortical magnification factor; visual field; retinotopic map; flat-mount; V1; V2; amblyopia ...
... Key words: cytochrome oxidase; cortical magnification factor; visual field; retinotopic map; flat-mount; V1; V2; amblyopia ...
View/Open - DukeSpace
... The paradox of the SEF – that it seems so saccade related but is so blatantly unnecessary for generating saccades – and the early findings on multiple coordinate systems in the SEF inspired a new generation of experiments that have been very informative. This nascent research posits a higher level f ...
... The paradox of the SEF – that it seems so saccade related but is so blatantly unnecessary for generating saccades – and the early findings on multiple coordinate systems in the SEF inspired a new generation of experiments that have been very informative. This nascent research posits a higher level f ...