studies on formulation and evaluation of floating tablet
... suppress the secretion of gastric acid. common example is cimetidine , ranitidine.2 Nizatidine is used for the treatment of acid-reflux disorders, peptic ulcer disease, active benign gastric ulcer and active duodenal ulcer. Nizatidine is a competitive, reversible inhibitor of histamine at the H2-rec ...
... suppress the secretion of gastric acid. common example is cimetidine , ranitidine.2 Nizatidine is used for the treatment of acid-reflux disorders, peptic ulcer disease, active benign gastric ulcer and active duodenal ulcer. Nizatidine is a competitive, reversible inhibitor of histamine at the H2-rec ...
Syllabus of Pharmaceutical Chemistry (PC)
... 1. Molecular basis of drug action: a) Receptor: Drug Receptor Interaction: Basic ligand concept, agonist, antagonist, partial agonist, inverse agonist, receptor Theories - Occupancy, Rate & Activation Theories, receptor Binding Assays, determination of B-max and Kd by transforming data with Hill plo ...
... 1. Molecular basis of drug action: a) Receptor: Drug Receptor Interaction: Basic ligand concept, agonist, antagonist, partial agonist, inverse agonist, receptor Theories - Occupancy, Rate & Activation Theories, receptor Binding Assays, determination of B-max and Kd by transforming data with Hill plo ...
ANTIDIABETIC ACTIVITY OF SOME HERBAL DRUG
... preparation lowered blood glucose level from the peak 190.8 ± 7.0 mg/dl to 111.0. ± 8.5 mg/dl, while the conventional drug, Diamicron, lowered glucose levels from 190.8 ±7.5 mg/dl to 125.5 ± 2.1 mg/dl. These effects were found not to be significantly different (p > 0.05). Hence, herbal drug alternat ...
... preparation lowered blood glucose level from the peak 190.8 ± 7.0 mg/dl to 111.0. ± 8.5 mg/dl, while the conventional drug, Diamicron, lowered glucose levels from 190.8 ±7.5 mg/dl to 125.5 ± 2.1 mg/dl. These effects were found not to be significantly different (p > 0.05). Hence, herbal drug alternat ...
Anxiolytic, hypnotic
... • Which one of the following is most likely to result from treatment with moderate doses of diazepam? (A) Alleviation of the symptoms of major depressive disorder (B) Agitation and possible hyperreflexia with abrupt discontinuance after chronic use (C) Increased porphyrin synthesis (D) Improved perf ...
... • Which one of the following is most likely to result from treatment with moderate doses of diazepam? (A) Alleviation of the symptoms of major depressive disorder (B) Agitation and possible hyperreflexia with abrupt discontinuance after chronic use (C) Increased porphyrin synthesis (D) Improved perf ...
Drugs from nature" past achievements, future prospects
... Plants have a long history of use in the treatment of cancer, 19 though many of the claims for the efficacy of such treatment should be viewed with some skepticism because cancer, as a specific disease entity, is likely to be poorly defined in terms of folklore and traditional medicine. 2~ Of the pl ...
... Plants have a long history of use in the treatment of cancer, 19 though many of the claims for the efficacy of such treatment should be viewed with some skepticism because cancer, as a specific disease entity, is likely to be poorly defined in terms of folklore and traditional medicine. 2~ Of the pl ...
Pharmaceutical Slides - Public Health and Social Justice
... visits) • Only ½ of samples go to patients »Providers dispense samples at 10% 20% of visits • 60% of pharm reps self-medicate ...
... visits) • Only ½ of samples go to patients »Providers dispense samples at 10% 20% of visits • 60% of pharm reps self-medicate ...
Nausea and Vomiting
... treatment of nausea and vomiting in palliative care patients OBJECTIVES By the end of the session you will be able to ...
... treatment of nausea and vomiting in palliative care patients OBJECTIVES By the end of the session you will be able to ...
Referral patterns in de-addiction services
... de-addiction service providers all over India (mainly government service providers), and keeps track of the current drug abuse pattern and notes change in pattern of drug abuse over years2. It contains service provider’s identification, basic socio-demographic data of the patient, a checklist of dru ...
... de-addiction service providers all over India (mainly government service providers), and keeps track of the current drug abuse pattern and notes change in pattern of drug abuse over years2. It contains service provider’s identification, basic socio-demographic data of the patient, a checklist of dru ...
Seminar On Altered kinetics in pediatrics
... (between age 1-4 (at puberty) years then progressively ↓) ...
... (between age 1-4 (at puberty) years then progressively ↓) ...
Drugs of Abuse - QML Pathology
... For both urine and oral fluid, drug testing is usually a two-step process – the screening test and the confirmatory test. The screening step may be performed on-site at the workplace and provides a relatively quick and inexpensive process to establish whether a drug or drug class, is likely to be pr ...
... For both urine and oral fluid, drug testing is usually a two-step process – the screening test and the confirmatory test. The screening step may be performed on-site at the workplace and provides a relatively quick and inexpensive process to establish whether a drug or drug class, is likely to be pr ...
Toxicological Findings in Cases of Alleged Drug
... the 23 cases is shown in Table 8. The most common combination of three illicit drugs was cannabis, cocaine and Ecstasy. One sample contained four illicit drugs. b) Other drugs The results relating to other drugs detected in the 1014 cases are summarised in Table 9. The tests used in this laboratory ...
... the 23 cases is shown in Table 8. The most common combination of three illicit drugs was cannabis, cocaine and Ecstasy. One sample contained four illicit drugs. b) Other drugs The results relating to other drugs detected in the 1014 cases are summarised in Table 9. The tests used in this laboratory ...
PEC Pipeline: Looking into the Crystal Ball LCDR Joe Lawrence, MSC, USN
... – PEC completes analyses and provides recommendations to DoD P&T – DoD P&T considers all alternatives and forwards collective recommendation to TMA director – BAP comments on P&T Committee recommendations – TMA Director concurs or non-concurs with Committee ...
... – PEC completes analyses and provides recommendations to DoD P&T – DoD P&T considers all alternatives and forwards collective recommendation to TMA director – BAP comments on P&T Committee recommendations – TMA Director concurs or non-concurs with Committee ...
NEUROCHEMICAL SELVES
... societies, notably Europe and the United States, became increasingly dependent on commercially produced pharmaceuticals. This is especially true in relation to psychiatry and mental health. We could term these "psychopharmacological" societies. They are societies where the modification of thought, m ...
... societies, notably Europe and the United States, became increasingly dependent on commercially produced pharmaceuticals. This is especially true in relation to psychiatry and mental health. We could term these "psychopharmacological" societies. They are societies where the modification of thought, m ...
Anticonvulsants. Sedatives. Behaviour
... Steady-state serum phenobarbital concentrations should be determined after 3 weeks of therapy. If a patient’s seizures are adequately controlled, then serum concentrations may be determined again after 3–6 months. If a patient’s seizures are not adequately controlled after 3 weeks of therapy, the d ...
... Steady-state serum phenobarbital concentrations should be determined after 3 weeks of therapy. If a patient’s seizures are adequately controlled, then serum concentrations may be determined again after 3–6 months. If a patient’s seizures are not adequately controlled after 3 weeks of therapy, the d ...
2016 MLI Biennial Drug Alch Policy Review
... nervous system, much lower doses of alcohol will produce the effects just described. Repeated use of alcohol can lead to dependence. Sudden cessation of alcohol intake is likely to produce withdrawal symptoms, including severe anxiety, tremors, hallucinations and convulsions. Long-term consumption o ...
... nervous system, much lower doses of alcohol will produce the effects just described. Repeated use of alcohol can lead to dependence. Sudden cessation of alcohol intake is likely to produce withdrawal symptoms, including severe anxiety, tremors, hallucinations and convulsions. Long-term consumption o ...
Blue Shield Reference Guide
... when prescribing medications for participants. When presented a prescription for a non-formulary drug, a pharmacist should attempt to contact the prescribing physician in order to suggest formulary alternatives. Physicians and pharmacists should be aware that, based on the specific terms of a patien ...
... when prescribing medications for participants. When presented a prescription for a non-formulary drug, a pharmacist should attempt to contact the prescribing physician in order to suggest formulary alternatives. Physicians and pharmacists should be aware that, based on the specific terms of a patien ...
Predicting Cardiac Risk of Anti-Cancer Drugs: A Role for Human
... Cardiotoxicity is a major complication of cancer therapy. It can occur after acute exposure to chemotherapeutic agents by direct effects on cardiac ion channels resulting in derangement of cardiac excitability and arrhythmias or develop with time in the form of ventricular dysfunction and heart fail ...
... Cardiotoxicity is a major complication of cancer therapy. It can occur after acute exposure to chemotherapeutic agents by direct effects on cardiac ion channels resulting in derangement of cardiac excitability and arrhythmias or develop with time in the form of ventricular dysfunction and heart fail ...
Anticoagulants
... • Fast action intravenously or by injection (not absorbed through the stomach or intestinal wall) • peak after injection 2 - 4 hr • Complex metabolism (long chains broken up) • half life 1 - 5 hr; cleared by the reticuloendothelial system and some excreted in urine. • A few Drug-drug interactions • ...
... • Fast action intravenously or by injection (not absorbed through the stomach or intestinal wall) • peak after injection 2 - 4 hr • Complex metabolism (long chains broken up) • half life 1 - 5 hr; cleared by the reticuloendothelial system and some excreted in urine. • A few Drug-drug interactions • ...
past, present and future - National Cancer Registry Ireland
... Pharmacoepidemiology in Ireland Since 1968 Ireland has participated in the WHO International Drug Monitoring System and pharmacoepidemiology was mainly in the area of Adverse drug reaction (ADR) reporting. The Yellow Card Scheme for ADR reporting has operated through the Irish Medicines Board since ...
... Pharmacoepidemiology in Ireland Since 1968 Ireland has participated in the WHO International Drug Monitoring System and pharmacoepidemiology was mainly in the area of Adverse drug reaction (ADR) reporting. The Yellow Card Scheme for ADR reporting has operated through the Irish Medicines Board since ...
propafenone
... • Follow all directions on your prescription label. Your doctor may occasionally change your dose to make sure you get the best results. Do not take this medicine in larger or smaller amounts or for longer than recommended. ...
... • Follow all directions on your prescription label. Your doctor may occasionally change your dose to make sure you get the best results. Do not take this medicine in larger or smaller amounts or for longer than recommended. ...
PDF - Bentham Open
... are available for targeted drug delivery [3]. Lipid-based carriers are chosen, especially in lovastatin nanoparticles synthesis, due to some of the drawbacks of all other supporting materials. Lovastatin solid lipid nanoparticles (SLNs) are one such example for lipid-based carriers made from solid l ...
... are available for targeted drug delivery [3]. Lipid-based carriers are chosen, especially in lovastatin nanoparticles synthesis, due to some of the drawbacks of all other supporting materials. Lovastatin solid lipid nanoparticles (SLNs) are one such example for lipid-based carriers made from solid l ...
Daclatasvir - Daklinza - Bristol
... polypeptide (OATP) 1B1 and 1B3, and breast cancer resistance protein (BCRP). Administration of DAKLINZA may increase systemic exposure to medicinal products that are substrates of P-gp, OATP 1B1 or 1B3, or BCRP, which could increase or prolong their therapeutic effect or adverse reactions (see Table ...
... polypeptide (OATP) 1B1 and 1B3, and breast cancer resistance protein (BCRP). Administration of DAKLINZA may increase systemic exposure to medicinal products that are substrates of P-gp, OATP 1B1 or 1B3, or BCRP, which could increase or prolong their therapeutic effect or adverse reactions (see Table ...
Drug interaction
A drug interaction is a situation in which a substance (usually another drug) affects the activity of a drug when both are administered together. This action can be synergistic (when the drug's effect is increased) or antagonistic (when the drug's effect is decreased) or a new effect can be produced that neither produces on its own. Typically, interactions between drugs come to mind (drug-drug interaction). However, interactions may also exist between drugs and foods (drug-food interactions), as well as drugs and medicinal plants or herbs (drug-plant interactions). People taking antidepressant drugs such as monoamine oxidase inhibitors should not take food containing tyramine as hypertensive crisis may occur (an example of a drug-food interaction). These interactions may occur out of accidental misuse or due to lack of knowledge about the active ingredients involved in the relevant substances.It is therefore easy to see the importance of these pharmacological interactions in the practice of medicine. If a patient is taking two drugs and one of them increases the effect of the other it is possible that an overdose may occur. The interaction of the two drugs may also increase the risk that side effects will occur. On the other hand, if the action of a drug is reduced it may cease to have any therapeutic use because of under dosage. Notwithstanding the above, on occasion these interactions may be sought in order to obtain an improved therapeutic effect. Examples of this include the use of codeine with paracetamol to increase its analgesic effect. Or the combination of clavulanic acid with amoxicillin in order to overcome bacterial resistance to the antibiotic. It should also be remembered that there are interactions that, from a theoretical standpoint, may occur but in clinical practice have no important repercussions.The pharmaceutical interactions that are of special interest to the practice of medicine are primarily those that have negative effects for an organism. The risk that a pharmacological interaction will appear increases as a function of the number of drugs administered to a patient at the same time.It is possible that an interaction will occur between a drug and another substance present in the organism (i.e. foods or alcohol). Or in certain specific situations a drug may even react with itself, such as occurs with dehydration. In other situations, the interaction does not involve any effect on the drug. In certain cases, the presence of a drug in an individual's blood may affect certain types of laboratory analysis (analytical interference).It is also possible for interactions to occur outside an organism before administration of the drugs has taken place. This can occur when two drugs are mixed, for example, in a saline solution prior to intravenous injection. Some classic examples of this type of interaction include that Thiopentone and Suxamethonium should not be placed in the same syringe and same is true for Benzylpenicillin and Heparin. These situations will all be discussed under the same heading due to their conceptual similarity.Drug interactions may be the result of various processes. These processes may include alterations in the pharmacokinetics of the drug, such as alterations in the absorption, distribution, metabolism, and excretion (ADME) of a drug. Alternatively, drug interactions may be the result of the pharmacodynamic properties of the drug, e.g. the co-administration of a receptor antagonist and an agonist for the same receptor.