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Transcript
Drugs used for Alzheimer disease
Generic name
Manufacturer
Distributer
CLINICAL USES
1.Galantamine
Trade
name
Reminyl
Janssen
Mina drug
store
Used to treat
mild to
moderate
Alzheimer
disease
2.Rivastigmine
Exelon
Novartis
3.Donepezil
Aricept
4.Memantine
Ebixa
SIDE
EFFECTS
Nausea
vomiting,
diarrhea,
dizziness,
loss of
appetite,
weight loss
CONTRAINDICATIONS
Exelon should not be
given to :
Patients with
hypersensitivity to
rivastigmine or any
excipient.
Pregnant women &
breast feeding
mothers.
Donepezil (Aricept)
should be used with
caution in patient with
cardiac disease, cardiac
conduction
disturbances, chronic
obstructive pulmonary
disease, asthma.
‫مستودع األدوية‬
‫األردني‬
Used to treat
mild to
moderate
Alzheimer
disease
Nausea
Vomiting
Weight loss
Diarrhea
Loss of
apetite
Eisai (japan)
Nairoukh drug
store
Used to treat
mild to
moderate
Alzheimer
disease
Dizziness
Insomnia
Generalized
pain
Nausea
vomitting
Lundbeck Ltd
‫مستودع أبو شريف‬
It prevents the
rate of
memory loss
in Alzheimer
disease
Headache
Sleepiness
Constipation
Dizziness
High blood
pressure
Reminyl is
contraindicated in
patients with
hypersensitivity to
galantamine or other
excipients and also in
patients with severe
hepatic impairement.
Ebixa should not be
given to:
Patients with
hypersensitivity to
donepezil or any
excipients.
Pregnant women &
breast feeding
mothers..
Drugs for psychiatric disorders
Generic
Trade
Name
name
`1.Haloperido Serenace
l
Haldol
Manufacturer
Distributers
Clinical uses
Side effects
Pfizer
Al sabbagh
drug store
Mina drug
store
Acute
psychosis &
acute manic
phases.
2.Clozapine
Leponex
Novartis
Clozapin
e
Remidica
The Jordan
drug store
Al salem drug
store
Management
of psychotic
disorders
including
schizophrenia.
Extrapyramidal
dysfunction,
blurred vision,
insomnia, and
hair
loss,Constipati
on; diarrhea;
dizziness;
drowsiness; dry
mouth;
headache; loss
of appetite;
nausea;stomac
h upset.
Agranulocytosi
s
Diabetes
Weight gain
Prexal
Joswe
Zyprexa
Lilly
Schizophrenia
Bipolar
disorders
Pranza
Hikma
Trust drug
store
‫مستودع أمين‬
‫شقير‬
Hikma drug
store
Diabetes,Weig
ht
gain,gynecoma
stia,
galactorrhea,in
creased blood
pressure
Risperdal
Janssen-cilag
Respal
Joswe
Rispharm
Pharma
international
Mina drug
store
Trust drug
store
Jerusalem
drug store
Acute and
chronic
schizophrenic
psychoses&
psychotic
conditions.use
Hyperprolacten
emia
Insomnia
Agitation
Headache
anxiety
3.Olanzapine
4.Risperidon
e
Janseen
pharmaceutica
contraindicatio
ns
Contraindicate
d in patients
with CNS
depression,
parkinsonism,
in coma
individuals with
uncontrolled
epilepsy,
myeloproliferat
ive disease, or
agranulocytosis
with prior
clozapine
treatment
should not be
given clozapine
products.
Should not be
given to
patients with
hypersensitivit
y to olanzapine
or other
ingredients,
also it should
not be given to
pregnant
females &
lactating
mothers.
Pregnant
females and
breast feeding
mothers as
well as patients
with
d also for
manic episodes
in bipolar
disordes.
5.Quetiapine
Seroquel
Astrazeneca
Omnia drug
store
Treatment of
schizophrenia,
manic and
depressive
episodes in
bipolar
disorders.
Somnolence
Dizziness
Dry mouth
Mild asthenia
Constipation
Tachycardia
Orthostatic
hypotension
dyspepsia
6.Ziprasidone
Zeldox
Pfizer
Al sabbagh
drug store
Treatment of
schizophrenia.
Asthenia
Headache
Constipation
Dry mouth
Dyspepsia
Nausea
Vomiting
somnolence
7. Lithium
carbonate
Camcolit
Norgine
Khory drug
store
Bipolar
affective
disorders
Tremor
Edema
Hypothyroidis
m
Renal
dysfunction
hypersensitivit
y to
risperidone or
other
excipients
should not use
any of
resperidone
products.
Patients with
hypersensitivit
y to Quetiapine
or any other
ingredient as
well as
pregnant
females &
breast feeding
mothers should
not use
seroquel.
Patients with
hypersensitivit
y to
ziprasidone or
any of the
excipients
,patients with
known QT
prolongation or
recent MI, as
well as
pregnant and
breast feeding
females should
not use zeldox.
Lithium
clearance is
reduced by
diuretics,NSAID
's.
Drugs used for Epilepsy
Generic Name
Phenytoin
Trade
name
Epanutin
Carbatol
Manufacturer
Park-Davis
Dar AL Dawa
Distributers
Clinical uses
Side effects
contraindications
Sabbagh
generalized
tonic-clonic
and partial
seizure.
ataxia , diplopia,
gingival
hyperplasia,
hirsutism ,
neuropathy
if you are allergic
(hypersensitive) to
Phenytoin, or any
of the other
ingredients
Dar AL Dawa
Carbamazepine
Tegretol
Clonazepam
Rivotril
Novartis
Jerdana
F.Hoffmann
La- Roche
Shawi &
Rushedat Drug
Store
generalized
tonic-clonic
and partial
seizure.
ataxia , diplopia,
headache,
nausia
absence and
myoclonic
seizures ,
infantile
spasm
sedation
* allergic to
carbamazepine or
to any ingredients
of the tablets or
suspension
* allergic to
tricyclic
compounds such
as amitriptyline,
trimipramine, or
imipramine
*has liver disease
*has a history of
acute intermittent
porphyria
*has a history of
hyponatremia
*has a serious
blood disorder
*has a history of
bone marrow
depression
*has taken an
MAO inhibitor
within the past 14
days or will take
one within the
next 14 days
*has certain kinds
of heart rhythm
disturbances (AV
block)
Clonazepam
should not be used
in patients with a
history of
sensitivity to
benzodiazepines or
in patients with
significant liver
dysfunctioin. It is
also
contraindicated in
patients with acute
narrow angle
glaucoma
Neurotin
Pfizer
Pregabalin
Lyrica
Lamictal
Al-Hikma
Pfizer
gsk
Sabbagh
Tannos
loxol
Al-Hikma
Al-Hikma
Epitam
Al-Hikma
Al-Hikma
Leveliracetam
Topiramate
Topamax
UCB
Pharmaceutica
ls Inc.
Janssen Cilag
partial seizure
ataxia ,dizzeness,
somnolence
You should not use
Lyrica if you are
allergic to
pregabalin.
Al-Hikma
Lamotrigine
Keppra
ataxia ,dizzeness,
somnolence
Sabbagh
Gababentin
Gabatrex
generalized
tonic-clonic
and partial
seizure.
Patients who are
allergic to
gabapentin or
other ingredients
should not take
gabapentin.
Gabapentin may
worsen absence
and myoclonic
seizures, so
caution should be
observed if the
patient might have
these seizure
types.
Tannos
Ninos
generalized
tonicclonic,partial,
myoclonic,and
absence
seizure.
dizzenes,diplopia
, headache , rash
Generalized
tonic clonic
and partial
seizures
dizzenes,
nervousness ,
depression ,
seizures.
generalized
tonicclonic,partial,
and absence
seizure
sleepness ,
cognitive slowing
,confusion ,
paresthesia.
lamotrigine is
contraindicated in
patients who have
demonstrated
hypersensitivity to
the drug or its
ingredients
This product
should not be
administered to
patients who have
previously
exhibited
hypersensitivity to
levetiracetam or
any of the inactive
ingredients
Patients who are
allergic to
topiramate should
not take Topamax.
Patients with a
history of kidney
stones or those
taking high-dose
vitamin C or
calcium
supplementation
should not take
Topamax because
of the increased
risk of kidney
stones.
Sedatives and Hypnotics
Generic
Name
Zolpidem
Tartarat
diazepam
Trade
name
stilnox
Stedon
Manufacturer
sanofisynthellabo
Adelco
Distributers
Clinical uses
Side effects
Nabulsi drug
store
Initiate and
maintain sleep
in insomnia
patients.
• drowsiness
• dizziness
• headache
• diarrhoea,
nausea and
vomiting
• muscle weakness
Jarzeem drug
store
Anxiety
disorders and
symptomatic
treatment of
organic
anxiety
Insomnia
associated
with anxiety. It
is also used in
status
epilepticus,
alcohol
withdrawal
syndrome as
adjunctive
therapy, as
muscle
relaxant and in
anesthesia.
drowsiness,
fatigue, and ataxia
(loss of balance)
contraindications
Do not take STILNOX
if you have:
• been drinking
alcohol or you
believe that you may
have
alcohol in your
bloodstream
• sleep apnoea
• myasthenia gravis
• severe liver
problems
• acute and/or
severe lung problems
• Do not take
STILNOX if you are
allergic to it or any of
the
ingredients
*Serious Myasthenia
*Hypersensitivity to
benzodiazepines or
to any of the
excipients
*Severe respiratory
insufficiency
*The syndrome of
sleeping apnea
*Serious liver
insufficiency
*Acute pulmonary
insufficiency
*Injections
containing benzyl
alcohol should be
avoided in neonates
*Caution is required
when diazepam is
administered in
patients with narrow
angle glaucoma
DIAZEPAM +
CLIDINIUM
BROMIDE
Lorazepam
DISTEDON
Adelco
Jarzeem drug
store
Lorans-1
Medochemie/
Cyprus
alHilal drug
store
xanax
Pfizer
khouri drug
store
Alprazolam
Prazin
Hikma
Hikma
Zolam
Ram
Pharmaceutica
l Industries Co.
Ltd
Ram
Pharmaceutica
l Industries Co.
Ltd
For the
symptomatic
treatment of
gastric and
duodenal
ulcer, gastritis,
duodenitis,
stomach
spasms,
motility
disorders of
bile duct,
spastic colitis,
mild ulcerative
colitis,
functional
constipation
and diarrhea,
urethral and
bladder
spasm,
dysmenorrhea
.it can restore
disturbed
autonomic
functions to
normal.
extension of CNS
depressant action
,tolerance,
dependence
liability
Sedativehypnotic,
antianxiety,
anticonvulsant
, antipanic
extension of CNS
depressant action
,tolerance,
dependence
liability
Xanax is used
to treat
anxiety.
Xanax is also
used to treat
panic
attacks.
extension of CNS
depressant action
,tolerance,
dependence
liability
It is contraindicated
to patients with
myasthenia,
glaucoma, prostate
hypertrophy as well
as for subjects with
known
hypersensitivity to
diazepam and or
clidinium bromide
DISTEDON should not
be used in the first
trimester of
pregnancy and from
nursing mothers.
*Allergy or
hypersensitivity to
contents *Severe
respiratory failure
*Acute intoxication
*Ataxia *Acute
narrow-angle
glaucoma *Sleep
apnea *Myasthenia
gravis *Pregnancy
and breast feeding
Do not take Xanax if
you have an allergy
to:
• any medicine
containing
alprazolam
• any of the
ingredients
• any other medicine
in the
benzodiazepine
group •myasthenia
gravis which
• severe and chronic
lung disease.
•Do not take this
medicine if you
are pregnant.
Chlordiazep
oxide
Proxidium
Hikma
Librax
ICN
Pharmaceutica
ls Switz Ltd
ORINT DRUG
STORE CO
Medospas
MEDOCHEMIE
Al Hilal Drug
Store
Lexotanil
F.Hoffmann
La- Roche
Shawi &
Rushedat Drug
Store
Bromazepa
m
thiopental
Hikma
Novepam
Ram
Pharmaceutica
l Industries Co.
Ltd
Ram
Pharmaceutica
l Industries Co.
Ltd
Lexopam
United
Pharmaceutica
l
Manufacturing
Co. Ltd
United
Pharmaceutica
l
Manufacturing
Co. Ltd
Thiopenta
l Vial
Sandoz GmbH
Nabulsi Drug
Store
Chlordiazepoxi
de is indicated
for the short
term (2–4
weeks)
treatment of
anxiety which
is severe and
disabling or
subjecting the
person to
unacceptable
distress. It is
also indicated
as a treatment
for the
management
of acute
alcohol
withdrawal
syndrome
Short-term
treatment of
anxiety or
panic attacks,
if a
benzodiazepin
e is required.
Premedication
to alleviate
anxiety before
surgery
anesthesia
•Drowsiness
•Coordination
problems
•Confusion.
Myasthenia gravis
Acute intoxication
with alcohol,
narcotics, or other
psychoactive
substances
Ataxia
Severe
hypoventilation
Acute narrowangle glaucoma
Severe liver
deficiencies
(hepatitis and liver
cirrhosis decrease
elimination by a
factor of 2)
Severe sleep apnea
Hypersensitivity or
allergy to any drug in
the benzodiazepine
class
extension of CNS
depressant action
,tolerance,
dependence
liability
Benzodiazepines
require special
precaution if used in
the elderly,
pregnancy, children,
alcohol- or drugdependent
individuals and
individuals with
comorbid psychiatric
disorders
extension of CNS
depressant action
,tolerance,
dependence
liability>
benzodiazepines
Thiopental should
not be given in case
of liver disease,
Addison's disease,
myxedema, severe
heart disease, severe
hypotension, a
severe breathing
disorder, or a history
of porphyria
Zolpidem
Tartarate
Stilnox
SanofiSynthelabo
Nabulsi Drug
Store
used to initiate
and maintain
sleep in
insomnia
patinents
extension of CNS
depressent effect ,
dependence
liability (•
drowsiness
• dizziness
• headache
• diarrhoea,
nausea and
vomiting
• muscle
weakness)
Do not take STILNOX
if you have:
• been drinking
alcohol or you
believe that you may
have
alcohol in your
bloodstream
• sleep apnoea (a
condition where
you temporarily stop
breathing
while you sleep)
• myasthenia gravis
(a condition
in which the muscles
become
weak and tire easily)
• severe liver
problems
• acute and/or
severe lung
problems
Do not take STILNOX
if you are
allergic to it or any of
the
ingredients