Prescription practice in patients of upper respiratory tract infection at
... Ibuprofen+Paractamol combination was the most commonly prescribed drug as Ibuprofen+Paractamol combination was more effective in relieving fever. Ibuprofen, Paracetamol and Mefenamic acid are the drug of choice for the fever in children. Paracetamol alone and in combination were the most prescribed ...
... Ibuprofen+Paractamol combination was the most commonly prescribed drug as Ibuprofen+Paractamol combination was more effective in relieving fever. Ibuprofen, Paracetamol and Mefenamic acid are the drug of choice for the fever in children. Paracetamol alone and in combination were the most prescribed ...
don*t bath with this stuff - Texas Counseling Association
... "Bath salts" are one of a multitude of marketing ...
... "Bath salts" are one of a multitude of marketing ...
5-Antifungal Chemotherapy
... Some of slides in this session are from the above mentioned format and are free for use by members of ASPET. Some others are from various sources like text book, recommended books, slides of Dr. S. Akbar (ex. professor, Pharmacology ,MUA). Core concepts of various USMLE High yield review serie ...
... Some of slides in this session are from the above mentioned format and are free for use by members of ASPET. Some others are from various sources like text book, recommended books, slides of Dr. S. Akbar (ex. professor, Pharmacology ,MUA). Core concepts of various USMLE High yield review serie ...
Drugs and sex differences: a review of drugs relating to anaesthesia.
... the extremes the curve is flattened. It is possible for example that sedative effects of progesterone affect the dose– response curves of drugs during the menstrual cycle by effects on the ED50 or at the extremes (i.e. ED10 and ED95). In this latter case, these alterations may be apparent only in so ...
... the extremes the curve is flattened. It is possible for example that sedative effects of progesterone affect the dose– response curves of drugs during the menstrual cycle by effects on the ED50 or at the extremes (i.e. ED10 and ED95). In this latter case, these alterations may be apparent only in so ...
Launch of Dovobet Ointment Topical Combination Drug for Psoriasis
... drug, and Kyowa Hakko Kirin is responsible for distribution and Medical Representatives (MRs) promotion of the drug. Both companies will jointly conduct marketing activities. Psoriasis is a chronic and intractable skin disease. In Japan, there are reportedly approximately 430,000 sufferers. Although ...
... drug, and Kyowa Hakko Kirin is responsible for distribution and Medical Representatives (MRs) promotion of the drug. Both companies will jointly conduct marketing activities. Psoriasis is a chronic and intractable skin disease. In Japan, there are reportedly approximately 430,000 sufferers. Although ...
Indication
... It can get into the lungs causing pneumonia, into the bladder/kidney causing UTI, or can cause serious blood borne infections. MRSA can be fatal! ...
... It can get into the lungs causing pneumonia, into the bladder/kidney causing UTI, or can cause serious blood borne infections. MRSA can be fatal! ...
Is there a difference between an angiotensin
... and 9% (95% CI: 3-14) by the ARB. Coronary heart disease was significantly reduced by the ACE inhibitor by 13% (95% CI: 3-21), but the ARB did not reduce coronary heart disease significantly. Heart failure was significantly reduced by both the ACE inhibitor and the ARB. When used as monotherapy, nei ...
... and 9% (95% CI: 3-14) by the ARB. Coronary heart disease was significantly reduced by the ACE inhibitor by 13% (95% CI: 3-21), but the ARB did not reduce coronary heart disease significantly. Heart failure was significantly reduced by both the ACE inhibitor and the ARB. When used as monotherapy, nei ...
Pathways of drug metabolism
... 56% of drugs that cause ADRs are metabolized by polymorphic phase I enzymes, of which 86% are CYP P450; only 20% of drugs associated with ADRs are substrates for non-polymorphic enzymes ADRs cause > 100 000 deaths/y in the USA Up to 7% of all hospital admissions in the UK and Sweden are due to ADRs ...
... 56% of drugs that cause ADRs are metabolized by polymorphic phase I enzymes, of which 86% are CYP P450; only 20% of drugs associated with ADRs are substrates for non-polymorphic enzymes ADRs cause > 100 000 deaths/y in the USA Up to 7% of all hospital admissions in the UK and Sweden are due to ADRs ...
Hyperlipidemias
... Atherosclerosis and coronary heart disease are associated with elevated levels of low density lipoprotein (LDL cholesterol) and triacyglycerol with low levels of HDL cholesterol. Other risk factors include smoking, hypertension, obesity, diabetes, lack of exercise and consumption of a diet containin ...
... Atherosclerosis and coronary heart disease are associated with elevated levels of low density lipoprotein (LDL cholesterol) and triacyglycerol with low levels of HDL cholesterol. Other risk factors include smoking, hypertension, obesity, diabetes, lack of exercise and consumption of a diet containin ...
Teacher Notes
... 25I-NBOMe. These drugs are usually extremely cheap to buy which has encouraged some young people to use them. They are usually taken by smoking, ingesting or injecting. Many younger drug users believe these drugs have a relatively low risk of addiction or overdose and are harmless compared with othe ...
... 25I-NBOMe. These drugs are usually extremely cheap to buy which has encouraged some young people to use them. They are usually taken by smoking, ingesting or injecting. Many younger drug users believe these drugs have a relatively low risk of addiction or overdose and are harmless compared with othe ...
DRUG DELIVERY - FILMS, STRIPS & DISKETTES
... It is difficult to incorporate hydrophobic species into layers under physiological conditions (pH 7.4) due to their limited functionality. This problem can be overcome by creating a hydrogen-bonded system, using tannic acid. The acid forms hydrogen bonds with the polymeric micelles ensuring that the ...
... It is difficult to incorporate hydrophobic species into layers under physiological conditions (pH 7.4) due to their limited functionality. This problem can be overcome by creating a hydrogen-bonded system, using tannic acid. The acid forms hydrogen bonds with the polymeric micelles ensuring that the ...
DRUG ABSORPTION, DISTRIBUTION AND ELIMINATION
... The distribution of a drug across the cell membrane is usually determined by its pKa and the pHs on both sides of a membrane. The difference of pH across a membrane influences the total concentration of drug on either side, since, by diffusion, at equilibrium the concentration of nonionized drug wil ...
... The distribution of a drug across the cell membrane is usually determined by its pKa and the pHs on both sides of a membrane. The difference of pH across a membrane influences the total concentration of drug on either side, since, by diffusion, at equilibrium the concentration of nonionized drug wil ...
Antimalerials - S. Vijaya lakshmi - Hindu college
... Antifolates include sulfonamides, pyrimethamine, proguanil and dapsone. These drugs act synergistically to target enzymes involved in folate synthesis, a pathway required for parasite DNA synthesis ...
... Antifolates include sulfonamides, pyrimethamine, proguanil and dapsone. These drugs act synergistically to target enzymes involved in folate synthesis, a pathway required for parasite DNA synthesis ...
Teaching health professionals about complementary and alternative
... The number of children who die, become ill or are put at risk of harmful side-effects from medication prescribed during their stay in hospital has dropped by more than half over the past four years, a project at the Sydney Children's Hospital has found. But despite the improvements, almost nine out ...
... The number of children who die, become ill or are put at risk of harmful side-effects from medication prescribed during their stay in hospital has dropped by more than half over the past four years, a project at the Sydney Children's Hospital has found. But despite the improvements, almost nine out ...
annexure – ii
... One of the major problems in the chronic treatment is the fact that the viral particles are able to reside in cellular and anatomical sites in the body following replication and remain viable even when there are adequate drug concentrations in the blood1. Although anti retro viral drug therapy has c ...
... One of the major problems in the chronic treatment is the fact that the viral particles are able to reside in cellular and anatomical sites in the body following replication and remain viable even when there are adequate drug concentrations in the blood1. Although anti retro viral drug therapy has c ...
Amphetamines Megan Trimble 3/28/06
... Defining the term: The more of this drug you consume, the higher you want get and the harder it is to do so. The user takes increasing amounts without sleeping which can result in being beyond high, for days at a time ...
... Defining the term: The more of this drug you consume, the higher you want get and the harder it is to do so. The user takes increasing amounts without sleeping which can result in being beyond high, for days at a time ...
stu narcotic analg..
... • It can also occur as a consequence of brain or nerve injury (e.g. following a stroke or herpes infection). Painful conditions of the latter kind, not directly linked to tissue injury, are very common and a major cause of disability and distress, and in general they respond less well to convention ...
... • It can also occur as a consequence of brain or nerve injury (e.g. following a stroke or herpes infection). Painful conditions of the latter kind, not directly linked to tissue injury, are very common and a major cause of disability and distress, and in general they respond less well to convention ...
Drugs and the kidney
... balance. The indications for diuretic use include heart failure (acute or chronic), pulmonary oedema, hypertension, nephritic syndrome, hypercalcaemia and hypercalciuria. Diuretic drugs increase urine output by the kidney, i.e. they promote diuresis. This is accomplished by altering the manner in wh ...
... balance. The indications for diuretic use include heart failure (acute or chronic), pulmonary oedema, hypertension, nephritic syndrome, hypercalcaemia and hypercalciuria. Diuretic drugs increase urine output by the kidney, i.e. they promote diuresis. This is accomplished by altering the manner in wh ...
A Review: Stereochemical consideration and eudismic ratio in chiral
... Single enantiomer drugs are increasingly consumer of enantiomeric fine chemicals, popular for the practicing physician. The contributing to a total North American manufacturers are keen to provide the share of $3.98 billion, making up 60% of optically pure drugs to avoid the the total. European and ...
... Single enantiomer drugs are increasingly consumer of enantiomeric fine chemicals, popular for the practicing physician. The contributing to a total North American manufacturers are keen to provide the share of $3.98 billion, making up 60% of optically pure drugs to avoid the the total. European and ...
Pharmacodynamics (08)
... receptors occupied, it can be stated that at binding equilibrium, the drug effect would be also be constant. Affinity describes the strength of binding to receptors, Drugs that bind with great avidity to the receptors are said to have high affinity. The term most often used to represent affinity is ...
... receptors occupied, it can be stated that at binding equilibrium, the drug effect would be also be constant. Affinity describes the strength of binding to receptors, Drugs that bind with great avidity to the receptors are said to have high affinity. The term most often used to represent affinity is ...
Review of Principles
... Some tissues have more receptors than are necessary to produce a maximal response. – Dependent on tissue, measure of response and intrinsic efficacy of the drug. ...
... Some tissues have more receptors than are necessary to produce a maximal response. – Dependent on tissue, measure of response and intrinsic efficacy of the drug. ...
Drug interaction
A drug interaction is a situation in which a substance (usually another drug) affects the activity of a drug when both are administered together. This action can be synergistic (when the drug's effect is increased) or antagonistic (when the drug's effect is decreased) or a new effect can be produced that neither produces on its own. Typically, interactions between drugs come to mind (drug-drug interaction). However, interactions may also exist between drugs and foods (drug-food interactions), as well as drugs and medicinal plants or herbs (drug-plant interactions). People taking antidepressant drugs such as monoamine oxidase inhibitors should not take food containing tyramine as hypertensive crisis may occur (an example of a drug-food interaction). These interactions may occur out of accidental misuse or due to lack of knowledge about the active ingredients involved in the relevant substances.It is therefore easy to see the importance of these pharmacological interactions in the practice of medicine. If a patient is taking two drugs and one of them increases the effect of the other it is possible that an overdose may occur. The interaction of the two drugs may also increase the risk that side effects will occur. On the other hand, if the action of a drug is reduced it may cease to have any therapeutic use because of under dosage. Notwithstanding the above, on occasion these interactions may be sought in order to obtain an improved therapeutic effect. Examples of this include the use of codeine with paracetamol to increase its analgesic effect. Or the combination of clavulanic acid with amoxicillin in order to overcome bacterial resistance to the antibiotic. It should also be remembered that there are interactions that, from a theoretical standpoint, may occur but in clinical practice have no important repercussions.The pharmaceutical interactions that are of special interest to the practice of medicine are primarily those that have negative effects for an organism. The risk that a pharmacological interaction will appear increases as a function of the number of drugs administered to a patient at the same time.It is possible that an interaction will occur between a drug and another substance present in the organism (i.e. foods or alcohol). Or in certain specific situations a drug may even react with itself, such as occurs with dehydration. In other situations, the interaction does not involve any effect on the drug. In certain cases, the presence of a drug in an individual's blood may affect certain types of laboratory analysis (analytical interference).It is also possible for interactions to occur outside an organism before administration of the drugs has taken place. This can occur when two drugs are mixed, for example, in a saline solution prior to intravenous injection. Some classic examples of this type of interaction include that Thiopentone and Suxamethonium should not be placed in the same syringe and same is true for Benzylpenicillin and Heparin. These situations will all be discussed under the same heading due to their conceptual similarity.Drug interactions may be the result of various processes. These processes may include alterations in the pharmacokinetics of the drug, such as alterations in the absorption, distribution, metabolism, and excretion (ADME) of a drug. Alternatively, drug interactions may be the result of the pharmacodynamic properties of the drug, e.g. the co-administration of a receptor antagonist and an agonist for the same receptor.