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22 reflexes 1 - The reflex arc
22 reflexes 1 - The reflex arc

... This is what you call a MONOSYNAPTIC arc If there are any interneurons in the way between the afferent and the efferent neurons, this is called a POLYSYNAPTIC arc. There can be anywhere up to 200 synapses in a polysynaptic arc In the childish diagram above, some important elements have been omitted: ...
Nervous System
Nervous System

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... 1. Action potential arrives at axon terminal of presynaptic neuron 2. Synaptic vesicles rupture, releasing neurotransmitter into synapse 3. Neurotransmitter diffuses across synapse & binds to receptor protein on postsynaptic cell 4. Postsynaptic cell is excited or inhibited 5. Neurotransmitter in sy ...
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... but one input is eliminated from each fiber. This occurs by branch removal rather than motor neuron death. ...
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HGSS Chapter 2: The Cell

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Chapter 12 The Nervous System
Chapter 12 The Nervous System

... the skin are stimulated. These nerve endings are the dendrites of the sensory neuron and require a strong stimulus to activate it. The impulse travels along the sensory neuron to the spinal cord where the signal is passed along to the interneuron. The interneuron sends an impulse to the motor neuron ...
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... move from 1 location to another in the form of action potentials along neurons  Also known as nerve impulses  Messages move across the synapse Can ...
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Biology 2401 Anatomy and Physiology I notes

... - synaptic knobs contain membrane sacs called vesicles that are filled with molecules of a chemical messenger called a neurotransmitter - when the action potential reaches the synaptic knob electrically gated Ca++ channels open, allowing Ca++ to enter the cell, causing the vesicles to merge with the ...
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Ch 49 Pract Test Nervous System

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Motor Unit and All or None principle
Motor Unit and All or None principle

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Motor Units and Motor Neuron Disease

... Neuronal cell death is mediated by the process of apoptosis (‘cell suicide’). Cell death signals are modulated by a family of proteins known as BCL-2. These are stimulated by various death signals (including DNA damage, growth factor deprivation, death receptor activation etc.) and act on the mitoch ...
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topic 6.5 Neurons

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Motor Neuron - papbiobellaire

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... - can release transmitter in some neurons - contain ribosomes which means they can potentially make proteins locally! - vary in diameter… generally thick proximal, thinner distally -contain lots of actin Axons: ...
Target-cell-specific concentration of a metabotropic glutamate
Target-cell-specific concentration of a metabotropic glutamate

... terminals is regulated by presynaptic receptors responding to transmitters released fro m the same nerve terminal or from terminals of other neurons. The release of glutamate, the major excitatory neurotransmitter, is suppressed by presynaptic auto· receptors'-J. Here we show that a metabotropic glu ...
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Quiz Answers

... sensory nerves, the ability of the neurons to transmit sensory information will be inhibited. This loss of sensory information would be experienced as a “numbness” in areas exposed to the toxin. 15. Paralysis is a term used to describe the loss of function of muscle. If tetrodotoxin ’s effect is on ...
Nervous System - Intermediate School Biology
Nervous System - Intermediate School Biology

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chapter 15 - Victoria College
chapter 15 - Victoria College

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Neuromuscular junction



A neuromuscular junction (sometimes called a myoneural junction) is a junction between nerve and muscle; it is a chemical synapse formed by the contact between the presynaptic terminal of a motor neuron and the postsynaptic membrane of a muscle fiber. It is at the neuromuscular junction that a motor neuron is able to transmit a signal to the muscle fiber, causing muscle contraction.Muscles require innervation to function—and even just to maintain muscle tone, avoiding atrophy. Synaptic transmission at the neuromuscular junction begins when an action potential reaches the presynaptic terminal of a motor neuron, which activates voltage-dependent calcium channels to allow calcium ions to enter the neuron. Calcium ions bind to sensor proteins (synaptotagmin) on synaptic vesicles, triggering vesicle fusion with the cell membrane and subsequent neurotransmitter release from the motor neuron into the synaptic cleft. In vertebrates, motor neurons release acetylcholine (ACh), a small molecule neurotransmitter, which diffuses across the synaptic cleft and binds to nicotinic acetylcholine receptors (nAChRs) on the cell membrane of the muscle fiber, also known as the sarcolemma. nAChRs are ionotropic receptors, meaning they serve as ligand-gated ion channels. The binding of ACh to the receptor can depolarize the muscle fiber, causing a cascade that eventually results in muscle contraction.Neuromuscular junction diseases can be of genetic and autoimmune origin. Genetic disorders, such as Duchenne muscular dystrophy, can arise from mutated structural proteins that comprise the neuromuscular junction, whereas autoimmune diseases, such as myasthenia gravis, occur when antibodies are produced against nicotinic acetylcholine receptors on the sarcolemma.
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