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Dealing with the Trilemma: Optimal Capital Controls with Fixed
Dealing with the Trilemma: Optimal Capital Controls with Fixed

... exports shocks, foreign consumption shocks and shocks to wealth—the latter captures fluctuations in the price of commodities. We analyze different price setting assumptions: flexible prices, rigid prices, one-period in advance sticky prices, and Calvo price setting. We characterize the way a country ...
Study on The Effect of Paliurus spina
Study on The Effect of Paliurus spina

... clinical investigation towards the treatment of hyperlipidemia. This can explain the reason for its use in traditional medicine as a lipidlowering plant. Further studies are needed to understand the exact mechanism of action of this plant. ...
Intake of High-Fat Food Is Selectively Enhanced by Mu Opioid
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... rats were administered an intra-ACB infusion of DAMGO (2.5 mg) or saline (injections spaced 2 days apart), in combination with the 24-hr food deprivation. One week later, the same group of rats were treated with intra-ACB microinfusion of naltrexone (20 mg) or saline. Diet intake over 3 hr was calcu ...
IOSR Journal of Pharmacy and Biological Sciences (IOSR-JPBS)
IOSR Journal of Pharmacy and Biological Sciences (IOSR-JPBS)

... dose dependent increase in mean relative liver/kidney weight and liver/kidney injury at the doses studied. Numerous studies have demonstrated that bromocriptine causes significant reductions in body weight in both animal (11-12) and human studies (13). In our study we did not observe any significant ...
C11 Chemistry 151 Whitesell The Provisional Progress of
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FORMULATION DEVELOPMENT, CHARACTERIZATION & ESTIMATION OF ACID
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... appealing route for the delivery of drugs. Of the various dosage forms administered orally, the tablet is one of the most preferred dosage forms because of its ease of manufacturing, convenience in administration, accurate dosing, stability compared with oral liquids, and because it is more tamperpr ...
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Metabolism and drug interactions of 3-hydroxy-3
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the pharmacokinetics of a thiazole benzenesulfonamide

... was returned 4 h after dosing. Water was available ad libitum throughout the experiment. The experiment was conducted as a two-period crossover study. In the first period, the monkeys received via nasogastric intubation a solution of 1 (10 mg/kg; 5 mg/ml) in 0.5% Methocel containing 0.02 M lactic ac ...
Statement on the use of EFV in children less than 3 years of age
Statement on the use of EFV in children less than 3 years of age

International Journal of Pharmaceutical Research & Analysis
International Journal of Pharmaceutical Research & Analysis

... (H+, K+) ATPase enzyme system at the secretory surface of gastric parietal cell. This effect is dose related and leads to both basal and stimulated gastric acid secretion irrespective of the stimulus [2]. Different analytical methods have been reported in the literature for the assay of mosapride an ...
A RUGGED AND ECONOMIC METHOD FOR THE ESTIMATION OF ARIPIPRAZOLE... SERUM BY LCMS/MS DETECTION FOR CLINICAL TRIALS
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... A convenient method for the determination of Aripiprazole in human serum has been developed. Aripiprazole was extracted from an aliquot of human serum using liquid-liquid extraction method and then injected into a liquid chromatograph, equipped with mass spectrometry detector. Internal standard meth ...
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... the lowest concentrations of vitamin D are associated with increased overall mortality [27], the data regarding a correlation between the concentration of 25(OH)D and prognosis are inconsistent. The cause and effect analysis is undoubtedly hindered by widespread deficiency of vitamin D in many popul ...
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... •Linear and quadratic functions •Explaining a functional relationship by using one variable to describe another variable. •Selecting the independent or dependent quantity in an equation or verbal description and justifying the selection Gather and record data and use data sets to determine functiona ...
Effects of pomegranate juice consumption on sperm quality
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... because of its many seeds. The aim of this study was to investigate the effects of pomegranate juice (PJ) consumption on sperm quality, spermatogenic cell density, antioxidant activity and testosterone level of male healthy rats. Methods: Twenty-eight healthy adult male Wistar rats were divided into ...
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... vein on the opposite arm from the infusion. If necessary, samples were taken from the same vein used for infusion, after extensive flushing. No major differences were observed between patients sampled by the 2 methods. The most likely error would be an overestimate in the early samples. Since most o ...
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Vitamin K and osteoporosis – facts and myths
Vitamin K and osteoporosis – facts and myths

... The type of menaquinone depends on the bacteria, participating in its synthesis. Vitamin K2-containing foodstuffs include: liver, eggs, butter, milk, cheeses and some vegetables. Natto is among the richest sources of vitamin K2 (mainly menaquinone-7). It is a product from fermented soybeans, which c ...
Determine by Doctor
Determine by Doctor

... assume that induction is complete within five to seven days, it is possible that the majority of induction occurs over the first one to three days. Finally, auto-induction of metabolism commonly cause changes in steady-state carbamazepine levels which are less than proportional to an increase in the ...
IOSR Journal of Pharmacy and Biological Sciences (IOSR-JPBS) ISSN: 2278-3008.
IOSR Journal of Pharmacy and Biological Sciences (IOSR-JPBS) ISSN: 2278-3008.

... The drug optimization can be achieved through Chronopharmacology. Chronopharmacology is the Science that deals with the variations in the pharmacological actions of various drugs over a period of 24 hours of the day. The biochemical, physiological and pathological variations of the 24 hour period in ...
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Plateau principle

The plateau principle is a mathematical model or scientific law originally developed to explain the time course of drug action The principle has wide applicability in pharmacology, physiology, nutrition, biochemistry and system dynamics. It applies whenever a drug or nutrient is infused or ingested at a relatively constant rate and when a constant fraction is eliminated during each time interval. Under these conditions, any change in the rate of infusion leads to an exponential increase or decrease until a new level is achieved. This behavior is also called an approach to steady state because rather than causing an indefinite increase or decrease, a natural balance is achieved when the rate of infusion or production is balanced by the rate of loss.An especially important use of the plateau principle is to study the renewal of tissue constituents in the human and animal body. In adults, daily synthesis of tissue constituents is nearly constant, and most constituents are removed with a first order reaction rate. Applicability of the plateau principle was recognized during radiotracer studies of protein turnover in the 1940s by Rudolph Schoenheimer and David Rittenberg. Unlike the case with drugs, the initial amount of tissue or tissue protein is not zero because daily synthesis offsets daily elimination. In this case, the model is also said to approach a steady state with exponential or logarithmic kinetics. Constituents that change in this manner are said to have a biological half-life.A practical application of the plateau principle is that most people have experienced ""plateauing"" during regimens for weight management or training for sports. After a few weeks of progress, one seems unable to continue gaining in ability or losing weight. This outcome results from the same underlying quantitative model. This entry will describe the popular concepts as well as development of the plateau principle as a scientific, mathematical model.In the sciences, the broadest application of the plateau principle is creating realistic time signatures for change in kinetic models (see Mathematical model). One example of this principle is the long time required to effectively change human body composition. Theoretical studies have shown that many months of consistent physical training and food restriction are needed to bring about permanent weight stability in people who were previously overweight.
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