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Cell cycle and Reproduction - River Dell Regional School District
Cell cycle and Reproduction - River Dell Regional School District

... Each human chromosome contains a single DNA double helix, about 50 million to 250 million nucleotides long Most of the time, the DNA in each chromosome is wound around proteins called histones These DNA-histone spools are further folded into coils Another layer of folding occurs as the coiled strand ...
DNAfor NathanLec - Sonoma State University
DNAfor NathanLec - Sonoma State University

... 1. elongation of complimentary strand – 5’ to 3’ a. done by DNA Polymerase - DNA polymerase can only add nucleotides to a pre-existing strand - requires RNA primer to begin - polymerase makes complimentary strand to template 2. Elimination of RNA Primer a. different DNA P’ase - eats away RNA with ex ...
Section 8.4: Transcription
Section 8.4: Transcription

...  RNA polymerases are used to bind the nucleotides together to make a new RNA molecule ...
Recap of 8.1 and 8.2
Recap of 8.1 and 8.2

... It passes from generation to generation without changing. 2. The two strands are linked only by hydrogen bonds: During DNA replication and protein synthesis, the strands can separate easily. 3. It’s a huge molecule: It can store vast amounts of information. 4. It’s coiled into a double helix. The in ...
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File

... Make a Single Strand of DNA ...
PPT
PPT

... • Like the rest of a chromosome and its genes, telomeres are sequences of DNA chains of chemical code. • Like other DNA, they are made of four nucleic acid bases: A, T, G, C. • Telomeres are made of repeating sequences of TTAGGG on one strand of DNA bound to AATCCC on the other strand. Thus, one sec ...
DNA Structure DNA Structure
DNA Structure DNA Structure

... the agent that passed from one cell to another in Griffith’s experiment actually alters the characteristics of the recipient cell, many scientists believed it must be the genetic material.  In 1944, Avery, MacLeod, and McCarty determined that the transforming agent was DNA. ...
Ledbetter Presentation 8/15/05
Ledbetter Presentation 8/15/05

... of Centromere Molecular Rulers for identification and “calibration” of supernumerary marker chromosomes – Most proximal unique genomic clone to each pericentromeric “junkyard” – 1 Mb contig plus 1 clone every 500 kb to 5 Mb away from pericentromeric region – Validated as unique FISH signal, map posi ...
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... Solutions to Selected End of Chapter 8 Problems Plus One More Class 1 1. This is not a trivial question! Check out Fig 8-11 which shows the H-bonding between A-T and G-C base pairs. Those “Watson-Crick” H-bonds that are part of holding the two DNA strands together which along with hydrophobic stacki ...
PowerLecture: Chapter 13
PowerLecture: Chapter 13

... • Strands can only be assembled in the 5’ to 3’ direction •continuous on just one parent strand. This is because DNA synthesis occurs only in the 5´ to 3´ direction. • discontinuous: short, separate stretches of nucleotides are added to the template, and then ligase fill in the gaps between them. ...
Lab 1 Introduction to nucleic acids Structural Properties
Lab 1 Introduction to nucleic acids Structural Properties

... Guanine pairs with cytosine (three Hbonds) and adenine pairs with thymine (two H-bonds) (law of complementary base pairing). ...
DNAMocktst
DNAMocktst

... How many hydrogen bonds are found between A and T? 21. How many hydrogen bonds are found between G and C? 22. Where do free floating nucleotides come from? 23. Why is replication referred to as semiconservative? 24. When replication is finished what are the two new strands called? 25. This enzyme c ...
BIOLOGY Wednesday Sub Work
BIOLOGY Wednesday Sub Work

... this strand with no problem, super fast!  c. The “Lagging Strand”: i. This is the strand on the original molecule which goes 5’  3’. ii. This is called the lagging strand because remember DNA polymerase can only lay down nucleotides starting at the 5’ end. That means the Lagging Strand is going in ...
The Chemistry of Inheritance
The Chemistry of Inheritance

... The double helix must unwind to expose the two template strands. This is usually accomplished by the action of another enzyme, helicase. Once the helix is unwound it must be “stabilized” in this open state. This is accomplished by single-stranded binding protein. Before DNA polymerase can extend a s ...
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... 5. DNA pol I – removes primers and replaces them with 6. DNA ligase – joins fragments “link em with ligase” ...
htt
htt

... such a way that they are complementary. Adenine always bonds to Thymine and Cytosine always bonds to Guanine.  Sugar-phosphate bonds form the backbone of the helix and hydrogen bonds form the bonds between the nitrogen bases. ...
Reading GuideDNAto protein(CH7)
Reading GuideDNAto protein(CH7)

... backbone, the sugar and phosphate are covalently bonded in alternating subunits. The sugar found in the structure of DNA is deoxyribose and it is here that the nitrogenous bases bind. In DNA, these nitrogenous bases are adenine, guanine, cytosine, and thymine. Can you draw a model of DNA? A few more ...
14. Central Dogma practice
14. Central Dogma practice

... To understand the Central Dogma and be able to use this knowledge in biology requires that you first learn to manipulate the DNA and RNA bases through the processes of replication, transcription and translation “on paper”. After you have a thorough understanding you can proceed to more challenging a ...
DNA REVIEW for TEST2016
DNA REVIEW for TEST2016

... 3. Chargaff’s Rule( You will be given the % of the bases of DNA in one strand and must be able to determine the % of bases in the double strand. 4. Watson and Crick-Explain their contribution to the discovery of DNA. 5. Explain the structure of DNA.(What is a nucleotide?) 12.2 DNA Replication 1. Lis ...
DNA REPLICATION
DNA REPLICATION

... http://highered.mcgrawhill.com/olcweb/cgi/pluginpop.cgi?it=swf::535::535::/sites/dl/free/0072437316/120076/bi o23.swf::How%20Nucleotides%20are%20Added%20in%20DNA%20Replication ...
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... strand since you will be going in the 3’ → 5’ direction which is easier for DNA polymerase III to follow b) helicase splits the double stranded DNA by breaking the hydrogen bonds between nucleotides 2) ​Topoisomerase​ keeps the strands from twisting together 3)​ ​Single-stranded DNA binding proteins ...
Chapter 16
Chapter 16

... 3. I can describe the structure of DNA, explain the base-pairing rule and describe its significance Questions to Answer These will be collected: 1. How did the work of TH Morgan and company contribute to the eventual discovery that DNA was the genetic material in the cell? 2. Explain the transformat ...
chapter11
chapter11

... DNA REPLICATION DNA can be precisely copied by a process called replication. The essential features of DNA replication are universal but there are some differences between prokaryotes and eukaryotes due to the difference in DNA organization. In prokaryotes, DNA consists of a circular double-stranded ...
Structure of DNA - Plain Local Schools
Structure of DNA - Plain Local Schools

... Transcription is the making of single stranded mRNA from a DNA strand within the nucleus of a cell. During transcription, RNA nucleotides base-pair one-by-one with DNA nucleotides on one of the DNA strands (called the template strand). RNA polymerase links the RNA nucleotides together. Base pairing ...
DNA ‐ The Double Helix
DNA ‐ The Double Helix

... Note
that
that
the
bases
attach
to
the
sides
of
the
ladder
at
the
sugars
and
not
the
phosphate.
 ...
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Telomere



A telomere is a region of repetitive nucleotide sequences at each end of a chromatid, which protects the end of the chromosome from deterioration or from fusion with neighboring chromosomes. Its name is derived from the Greek nouns telos (τέλος) 'end' and merοs (μέρος, root: μερ-) 'part.' For vertebrates, the sequence of nucleotides in telomeres is TTAGGG. This sequence of TTAGGG is repeated approximately 2,500 times in humans. During chromosome replication, the enzymes that duplicate DNA cannot continue their duplication all the way to the end of a chromosome, so in each duplication the end of the chromosome is shortened (this is because the synthesis of Okazaki fragments requires RNA primers attaching ahead on the lagging strand). The telomeres are disposable buffers at the ends of chromosomes which are truncated during cell division; their presence protects the genes before them on the chromosome from being truncated instead.Over time, due to each cell division, the telomere ends become shorter. They are replenished by an enzyme, telomerase reverse transcriptase.
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