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... In eukaryotic cells, the end of the linear chromosomes are composed of special nucleoprotein complexes known as telomeres, which are essential for chromosome integrity by protecting the chromosome ends from fusion and nuclease degradation, and by facilitating complete chromosome replication [1]. In ...
DNA - Northwest ISD Moodle
DNA - Northwest ISD Moodle

... 11. Which radioactive substance was injected into and took over the host cell's DNA? 12. What scientists showed the amount of the 4 nitrogen bases present in DNA? 13. Name the bases and their amounts found in somatic or body cells of humans. ...
Pretest Ch 12: DNA - Aurora City School
Pretest Ch 12: DNA - Aurora City School

... Prokaryotic DNA replication is different than eukaryotic. How…? 17. What shape does prokaryotic DNA have? ...
DNA polymerase
DNA polymerase

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Origins of Sugars in the Prebiotic World
Origins of Sugars in the Prebiotic World

... – Pb2+ binds to U59/C60 (if these are mutated  no binding) – Cleavage is specific  requires 2’-OH at B17 – One of few systems where x-ray structure is available revealing potential mechanism ...
DNA Quiz for Chapter 12
DNA Quiz for Chapter 12

... b. cytosine and guanine. c. DNA and RNA. d. thymine and adenine. 17. If the orientation of the top strand of DNA is 5’ to 3’ then the orientation of the bottom rail is a. 5’ to 3’ b. 1’ to 3’ c. 3’ to 5’ d. 1’ to 5’ 18. One of the basic differences between a DNA nucleotide and a RNA nucleotide is: a ...
DNA CFA B SB2. Students will analyze how biological traits are
DNA CFA B SB2. Students will analyze how biological traits are

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... 1. Use your two red pieces of licorice to assemble a strand of DNA with the following nucleotide sequence A-T-C-G. You will use the toothpicks to attach the nitrogen bases (gummy bears) to the sugar-phosphate backbones (licorice). 2. Attach the complementary nucleotides to the other side of the toot ...
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Deoxyribose nucleic acid

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Word Work File L_2.tmp

... A CHROMOSOME CONSISTS OF DNA AND PROTEINS Chromatin consists of DNS and histones. Chromatin is 10 nm thick. Proteins called histones are responsible for the first level of DNA packing. Most of the histone amino acids are positively charged (lysine or arginine) and bind tightly to the negatively char ...
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Chromosomes and Diseases - Faculty of Science at Bilkent
Chromosomes and Diseases - Faculty of Science at Bilkent

... Telomere: a sequence of DNA at the end of the chromosome whose function is to protect the ends of the chromosomal DNA strands during replication. Centromere: seen on a condensed chromosome as a pinched region, contains proteins which form kinetochores to attach the sister chromatids. ...
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Ch. 16 The Molecular Basis of Life

... ­do not contain genes ­contain multiple repetitions of a short   nucleotide chain ­TTAGGG ­number of repetitions can be 100 to 1,000 ­telomeres postpone the shortening of DNA   and the loss of genes on the ends of the   DNA molecules in normal cells ­also prevent cell death ­shortening of teleomeres ...
DNA Twizzler Model Lab - Manhasset Public Schools
DNA Twizzler Model Lab - Manhasset Public Schools

... B) Assemble one strand (twizzler) of your DNA molecule. a. Refer to the table to the right to choose the correct color marshmallow to represent the chemical bases in your sequence. b. Place a marshmallow on the end of a toothpick so that the point of the toothpick goes all the way through. Stick the ...
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... 1. In the spaces provided, write D if the statement is true of DNA. Write R if the statement is true of RNA. Write B if the statement is true of both DNA and RNA. _____ a. consists of a single strand of nucleotides _____ b. is made of nucleotides linked together _____ c. contains deoxyribose _____ d ...
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... DNA According to Watson & Crick (1953) ...
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... • Replication fork: region where the enzymes replicating a DNA molecule are bound to untwisted, single strand DNA • In replication fork, one strain is made continuously (leading strand) and the other strand can be only made in short segments (lagging strand) • Lagging strands consist of Okazaki frag ...
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... • Xeroderma pigmentosa (genetic disease) cannot go through process. • Disease prevents person from going in sun - UV rays interfere with DNA replication (more susceptible to skin cancer - can’t fix mistakes) ...
DNA & DNA Replication
DNA & DNA Replication

... Other enzymes needed to excise (remove) the primers Nuclease – removes the RNA primer nucleotide by nucleotide  Repair polymerase – replaces RNA with DNA  DNA ligase – seals the sugar-phosphate backbone by creating phosphodiester bond ...
Deamination of 5-methylcytosine yields thymine
Deamination of 5-methylcytosine yields thymine

... 2. Name the bases (full names, not just single letters) that make-up this mismatched base-pair. ...
Results of Exam 1 - Pennsylvania State University
Results of Exam 1 - Pennsylvania State University

... • Production of HL and disappearance of HH shows replication is NOT conservative. • Production of LL shows replication is NOT random. • Data support a semiconservative mode. • The parental DNA strands are used as templates for the synthesis of new strands, directed by base complementarity. ...
DNA Replication
DNA Replication

... DNA Structure & Function • Genetics: the study of heredity – What determines an organism’s traits (characteristics)? – How are traits passed on from one cell to another, and from parents to offspring? ...
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Chapter 16

... – Short nucleotide fragments – ~100-200 nucleotides long ...
Chapter 24
Chapter 24

... chain elongation because these nucleotide analogues do not have 3’-OH. 10. Telomeres and telomerase • In the lagging strand synthesis, a telomere (a short DNA with repeating G rich sequence) is attached at the 3’-end of chromosomes to complete the DNA synthesis. • Telomeres are synthesized by telome ...
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Telomere



A telomere is a region of repetitive nucleotide sequences at each end of a chromatid, which protects the end of the chromosome from deterioration or from fusion with neighboring chromosomes. Its name is derived from the Greek nouns telos (τέλος) 'end' and merοs (μέρος, root: μερ-) 'part.' For vertebrates, the sequence of nucleotides in telomeres is TTAGGG. This sequence of TTAGGG is repeated approximately 2,500 times in humans. During chromosome replication, the enzymes that duplicate DNA cannot continue their duplication all the way to the end of a chromosome, so in each duplication the end of the chromosome is shortened (this is because the synthesis of Okazaki fragments requires RNA primers attaching ahead on the lagging strand). The telomeres are disposable buffers at the ends of chromosomes which are truncated during cell division; their presence protects the genes before them on the chromosome from being truncated instead.Over time, due to each cell division, the telomere ends become shorter. They are replenished by an enzyme, telomerase reverse transcriptase.
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