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chronic congestive heart failure.
chronic congestive heart failure.

... were corrected to 20° C and to water as a solvent by the standard formula (15). A value of 0.728 was used for the partial specific volume of myosin. Diffusion measurements were made in an Aminco model B electrophoresis apparatus at 6° C, using carefully selected cells and the Raleigh interferometer ...
glucocorticoids activate cardiac mineralocorticoid receptors in
glucocorticoids activate cardiac mineralocorticoid receptors in

... growth factor (IGF)–1,20) cyclooxygenase (COX)–2,21) osteopontin,4) monocyte chemoattractant protein (MCP)–1,4) and the p22phox,22) gp91phox,22) p47phox,23) p67phox,23) and Rac123) subunits of NADPH oxidase. Reagents for detection of human 18S rRNA (Applied Biosystems) were used to quantify rat 18S ...
Articles in PresS. Am J Physiol Heart Circ Physiol (November 20
Articles in PresS. Am J Physiol Heart Circ Physiol (November 20

... processes in response to long-term ischemic injuries, such as permanent MI. Due to rapidly ...
Atrio-Ventricular Conduction with and without AV Nodal Delay: Two
Atrio-Ventricular Conduction with and without AV Nodal Delay: Two

... have a nodal morphology. Purple electrograms and OAPs are located along the SP. There is overlap in the characteristics of the brown and purple electrograms and OAPs. Traces shown in black were difficult to classify because they share characteristics of two types of activation. White traces were rec ...
the PDF - Heart Rhythm Society
the PDF - Heart Rhythm Society

... absolute and relative benefits and risks of those procedures and therapies can produce helpful guidelines that improve the effectiveness of care, optimize patient outcomes, and favorably affect the overall cost of care by focusing resources on the most effective strategies. The American College of C ...
Linking Cx43 and fibrosis
Linking Cx43 and fibrosis

... inhibitors (Zou 1999). Together these studies indicate that both α-adrenergic and βadrenergic receptors can act on the same pathways to induce similar effects like upregulation of Cx43 expression. As mentioned above chronic α- or βadrenergic stimulation during cardiac hypertrophy enhances Cx43 expre ...
Pericardial Diseases
Pericardial Diseases

... 2. Malignancy – A variety of hematologic and solid malignancies can cause pericardial metastases that are more frequently revealed during autopsy than during life. Typically, the diagnosis of malignancy has already been established in the patient with a malignant pericardial effusion, and other site ...
Phosphatase regulation in cardiovascular physiology and disease
Phosphatase regulation in cardiovascular physiology and disease

... The electrocardiogram is an important devise used to monitor and evaluate the pattern of electrical conduction through the heart. This devise uses a series of six limb leads and six precordial leads to allow a physician interpreter or cardiovascular researcher to visualize the average wave of depola ...
ACC/AHA/HRS 2008 Guidelines for Device-Based Therapy of Cardiac Rhythm Abnormalities
ACC/AHA/HRS 2008 Guidelines for Device-Based Therapy of Cardiac Rhythm Abnormalities

... absolute and relative benefits and risks of those procedures and therapies can produce helpful guidelines that improve the effectiveness of care, optimize patient outcomes, and favorably affect the overall cost of care by focusing resources on the most effective strategies. The American College of C ...
Restricting Excessive Cardiac Action Potential and QT Prolongation
Restricting Excessive Cardiac Action Potential and QT Prolongation

... L-735,821, or HMR-1556 produces little effect on action potential duration (APD) in isolated rabbit and dog ventricular myocytes, the effect of IKs block on normal human ventricular muscle APD is not known. Therefore, studies were conducted to elucidate the role of IKs in normal human ventricular mu ...
the mechanism of the wenckebach type of av block
the mechanism of the wenckebach type of av block

... by increasing the frequency of electrical stimulation, and felt that variable latency was responsible for the block, not diminished conductivity. Hering (1904) invoked the diastolic recovery of reactivity, or Reaktionsbereitschaft, of the ventricular muscle, linking in this term the myocardial prope ...
Reciprocal of Wall Thickness
Reciprocal of Wall Thickness

... (A) and thickness (H) of the section. Although A and H vary during the cardiac cycle, Vm is constant because the myocardium is incompressible. Isotropic wall tension, the average of circumferential and meridional wall tension (Te and T,), is invariant and takes the same value for every direction per ...
Atrial Fibrillation in Cardiac Surgery
Atrial Fibrillation in Cardiac Surgery

... was to study the relation between postoperative AF and inflammation; the longterm consequences of postoperative AF on mortality and late arrhythmia; and atrial function after concomitant surgical ablation for AF. In 524 open-heart surgery patients, C-reactive protein (CRP) serum concentrations were ...
Atrial Electric Signal During Sinus Rhythm in Lone
Atrial Electric Signal During Sinus Rhythm in Lone

... left ventricle, left ventricular magnetocardiogram, magnetocardiography, magnetocardiographic premature atrial complex duration of filtered P wave pulmonary vein right atrium, right atrial root mean square; root mean square amplitude signal average electrocardiogram standard deviation sinus rhythm W ...
the carotid pulse i: diagnosis of aortic stenosis by external
the carotid pulse i: diagnosis of aortic stenosis by external

Predicting Heart Growth During Puberty: The Muscatine
Predicting Heart Growth During Puberty: The Muscatine

... Two-dimensional echocardiograms were obtained with a Hewlett-Packard Ultrasound System (Andover, MA) with transducer selection determined by the child’s body size and image quality. The transducer was positioned according to the standards for transducer positions and imaging planes.15,16 A simultane ...
Editorials Original Articles - Circulation: Arrhythmia and
Editorials Original Articles - Circulation: Arrhythmia and

... Copyright © 2017 American Heart Association, Inc. All rights reserved. Print ISSN: 1941-3149. Online ISSN: 1941-3084 ...
Practical markers of the transition from aerobic to anaerobic metabolism
Practical markers of the transition from aerobic to anaerobic metabolism

... Despite the importance of exercise intensity, relatively little is currently known about the processes of self-monitoring and self-regulation of exercise intensity, particularly among formerly sedentary individuals going through the critical early stages of exercise involvement. The available studie ...
Acetylcholine stimulated dilatation and stretch induced myogenic
Acetylcholine stimulated dilatation and stretch induced myogenic

Reptilian Heart Development And The Molecular Basis Of
Reptilian Heart Development And The Molecular Basis Of

... understood. Reptilian hearts have been the subject of debate in the context of the evolution of cardiac septation: do they possess a single ventricular chamber or two incompletely septated ventricles4–7? We examined heart development in the red-eared slider turtle, Trachemys scripta elegans (a chelo ...
dbl dobutamine hydrochloride injection
dbl dobutamine hydrochloride injection

... oxygen supply, and thereby producing reversible clinical signs of myocardial ischaemia. These signs have included anginal pain, ST segment depression, thallium scintigraphic perfusion defects, and new wall motion abnormalities. Myocardial infarct size and the incidence and severity of ventricular ar ...
Slow Conduction in Cardiac Tissue, II
Slow Conduction in Cardiac Tissue, II

... Impulse Propagation Across Single Branch Points The characteristics of propagation along a preparation with a single branch point is shown in Figure 3. The videomicrograph (Figure 3A) shows the pattern consisting of a strand (horizontal) releasing two 460-mm-long branches (vertical). Activation of t ...
Ketone bodies disturb fatty acid handling in isolated cardiomyocytes
Ketone bodies disturb fatty acid handling in isolated cardiomyocytes

... due to a relatively high degree of variation between the individual experiments, the increase in the deposition of palmitate into the various lipid pools in the diabetic cells did not reach the level of significance. To evaluate the effect of varying the ambient palmitate concentration and the addit ...
The Systolic Murmur—Benign or Serious?
The Systolic Murmur—Benign or Serious?

... Figure 2. The beat following a premature ventricular contraction will usually exhibit an increase in outflow induced systolic murmur intensity because of the increased inotropic drive. The ventricular pressure will usually increase, as will the pressure gradient across a stenotic valve. Murmurs caus ...
Atrial natriuretic peptide (ANP)
Atrial natriuretic peptide (ANP)

... regarding the acute and chronic effects of the ANP release reduction and consequently abnormalities in the renal function related to body fluid control arising from cardiac surgeries where removal of the auricles is carried out. Furthermore, a number of clinical trials suggest that application of th ...
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Electrocardiography



Electrocardiography (ECG or EKG*) is the process of recording the electrical activity of the heart over a period of time using electrodes placed on a patient's body. These electrodes detect the tiny electrical changes on the skin that arise from the heart muscle depolarizing during each heartbeat.In a conventional 12 lead ECG, ten electrodes are placed on the patient's limbs and on the surface of the chest. The overall magnitude of the heart's electrical potential is then measured from twelve different angles (""leads"") and is recorded over a period of time (usually 10 seconds). In this way, the overall magnitude and direction of the heart's electrical depolarization is captured at each moment throughout the cardiac cycle. The graph of voltage versus time produced by this noninvasive medical procedure is referred to as an electrocardiogram (abbreviated ECG or EKG).During each heartbeat, a healthy heart will have an orderly progression of depolarization that starts with pacemaker cells in the sinoatrial node, spreads out through the atrium, passes through the atrioventricular node down into the bundle of His and into the Purkinje fibers spreading down and to the left throughout the ventricles. This orderly pattern of depolarization gives rise to the characteristic ECG tracing. To the trained clinician, an ECG conveys a large amount of information about the structure of the heart and the function of its electrical conduction system. Among other things, an ECG can be used to measure the rate and rhythm of heartbeats, the size and position of the heart chambers, the presence of any damage to the heart's muscle cells or conduction system, the effects of cardiac drugs, and the function of implanted pacemakers.
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