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executive summary. - Heart Rhythm Society
executive summary. - Heart Rhythm Society

... guidelines for management of patients with ventricular arrhythmias and the prevention of sudden cardiac death— executive summary: a report of the American College of Cardiology/American Heart Association Task Force and the European Society of Cardiology Committee for Practice Guidelines (Writing Com ...
ACC/AHA/ESC 2006 Guidelines for Management
ACC/AHA/ESC 2006 Guidelines for Management

... guidelines for management of patients with ventricular arrhythmias and the prevention of sudden cardiac death— executive summary: a report of the American College of Cardiology/American Heart Association Task Force and the European Society of Cardiology Committee for Practice Guidelines (Writing Com ...
Stroke volume-to-wall stress ratio as a load
Stroke volume-to-wall stress ratio as a load

... stress LOAD DEPENDENCE HAS LONG BEEN recognized in crude indicators of cardiac performance, such as stroke volume (SV) and ventricular pressures, based on the Starling principle, leading to the development of characteristic plots of load and crude performance (31, 50). The most popular of such chara ...
Regulation of atrial natriuretic peptide
Regulation of atrial natriuretic peptide

... of β-adrenoceptors, raised sodium concentration, angiotensin-II and endothelin. ANP binds to three cell surface receptors called ANP receptors. The overall effect of ANP on the body is to counter increases in blood pressure and volume caused by the renin-angiotensin system. It has also been reported ...
The Fontan circulation after 45 years: update in physiology
The Fontan circulation after 45 years: update in physiology

... Hospital survival has markedly improved with a reduction in mortality to 1%–2%. In the last couple of years, despite major efforts, ...
Open and Thoracoscopic Approaches to Treat Atrial Fibrillation and
Open and Thoracoscopic Approaches to Treat Atrial Fibrillation and

... success at maintaining sinus rhythm at one year of follow-up with thoracoscopic ablation, but also reported higher adverse event rates compared with catheter ablation. The case series generally report high success rates, and the few case series with matched comparison groups report higher success ra ...
Glucocorticoid receptor alters isovolumetric contraction and restrains
Glucocorticoid receptor alters isovolumetric contraction and restrains

... role for GR in maturing the foetal heart in preparation for life after birth. Hearts of foetal SMGRKO mice, which lack GR in cardiomyocytes and VSM, showed evidence of functional, structural and biochemical immaturity (RogZielinska et al. 2013). Consistent with this, glucocorticoid treatment of prim ...
Effects and mechanisms of curcumin on the
Effects and mechanisms of curcumin on the

... cholesterol diet (11). Thereby, it can exhibit a potential effect against atherosclerosis. Moreover, it has also been proposed in the treatment of idiopathic pulmonary arterial hypertension (12). In phase I clinical trials of oral curcumin in patients with advanced colorectal cancer, diarrhea and na ...
Appropriate Use Criteria for ICD/CRT Online Appendix Guideline
Appropriate Use Criteria for ICD/CRT Online Appendix Guideline

... An implantable cardioverter-defibrillator is recommended as secondary prevention to prolong survival in patients with current or prior symptoms of HF and reduced LVEF who have a history of cardiac arrest, ventricular fibrillation, or Hemodynamically destabilizing ventricular tachycardia (10-12). (Le ...
Repolarization reserve, arrhythmia and new drug development
Repolarization reserve, arrhythmia and new drug development

... excessive APD prolongation and proarrhythmia6,8. It recently has been reported that other currents also contribute to repolarization reserve. Several studies indicated that late sodium current (INa,L) was up-regulated by various factors and represented a functional reserve under disease conditions. ...
PDF - Circulation: Cardiovascular Imaging
PDF - Circulation: Cardiovascular Imaging

... The end-diastolic wall thickness in septum was not significantly different in the MI rats compared with sham, but the lateral wall (ie, in the ischemic regions) was thinner in all slices in MI (Table 2). Also, in the MI rats, the in-slice LV circumference was increased by 28% to 52% in all slices co ...
Surgery for Atrial Fibrillation - ANNALS Academy of Medicine
Surgery for Atrial Fibrillation - ANNALS Academy of Medicine

... fibrillation. These instruments create long linear lesions that block conduction using alternate energy sources such as radiofrequency, cryothermy, microwave, ultrasound and laser. The clinical experience amongst these is greatest with radiofrequency energy. Radiofrequency energy uses an alternating ...
The role of the pericardium in the valveless, tubular heart of the
The role of the pericardium in the valveless, tubular heart of the

... A numerical model of an elastic heart tube connected to a nearly rigid racetrack was constructed to study flow through the Ciona heart. The racetrack design was used for easy comparison to previous models of tubular heart pumping (Jung and Peskin, 2001; Hickerson et al., 2005; Baird et al., 2014; Av ...
Relation between regional function and coronary blood - AJP
Relation between regional function and coronary blood - AJP

... (0.56 mg/kg, DuPont Pharmaceutical) administered intravenously over 4 min. Dipyridamole was selected instead of adenosine because of its lower propensity to cause severe hypotension in anesthetized dogs. Its coronary vasodilatory effects are similar to that of adenosine (29). Data acquisition was in ...
the left atrium in hypertension: a symbol of mortality and morbidity?
the left atrium in hypertension: a symbol of mortality and morbidity?

... though left atrial enlargement was significantly greater among patients with LVH in the study by Tedesco et al [31], this group was significantly older compared to the group without LVH. As the authors admit, relationship between the left ventricular diastolic dysfunction and left atrial dimensions ...
Estimation of Heart-Surface Potentials Using Regularized Multipole
Estimation of Heart-Surface Potentials Using Regularized Multipole

... Abstract– Direct inference of heart-surface from bodysurface potentials has been the goal of most recent work on electrocardiographic inverse solutions. We developed and tested indirect methods for inferring heart-surface potentials based on estimation of regularized multipole sources. Regularizatio ...
Spotlight on atrial fibrillation—the `complete arrhythmia`
Spotlight on atrial fibrillation—the `complete arrhythmia`

... between pulse curves in clinical delirium cordis and those in dogs with induced auricular fibrillation [6]. Fredericq demonstrated the role of AF in causing the associated irregularity in ventricular contraction by cutting the bundle of His, after which the atria continued to fibrillate but the vent ...
a sample of the book
a sample of the book

... ulation than others do, such as high -cardiologists. This list includes 2,254 blood pressure and Marfan syndrome, top cardiologists who were selected the number of trusted references identhrough a peer nomination process; tified for each topic varies. 330 of them were also named to a Although heart ...
Haemodynamics in Essential Hypertension
Haemodynamics in Essential Hypertension

... 1976). In recent years, functional disturbances of the heart and resistance vessels together with morphological changes in the left ventricle (diagnosed by echocardiography) have been demonstrated surprisingly early, e.g. in subjects in their twenties with mild hypertension. This review will first d ...
Wyrwoll_PNAS_forMegan - Edinburgh Research Explorer
Wyrwoll_PNAS_forMegan - Edinburgh Research Explorer

... Collagen is a key contributor to cardiac wall stiffness. In fetuses from saline-treated dams, there ...
PDF Article
PDF Article

... Histological assessment. Myocyte diameters were measured separately in the inner, middle and outer thirds of the left ventricular free wall. Two investigators (M.A., T.I.), who were unaware of the treatment protocol, independently reviewed the sections and randomly selected a total of 100 myocardial ...
Flecainide: Current status and perspectives in arrhythmia
Flecainide: Current status and perspectives in arrhythmia

... studied extensively in comparison to either placebo or other antiarrhythmic agents (Table 2). However, the majority of the trials published in the literature are hampered by methodological limitations, such as open-label design, small sample size, suboptimal follow-up and underestimation of AF burde ...
morphology of posterior interventricular artery
morphology of posterior interventricular artery

... AbstractBackground: Coronary artery disease is one of the major causes of death in developing countries. The advanced diagnostic and therapeutic inventional procedures necessitate the sound knowledge of coronary artery pattern. Heart is supplied by two coronary arteries, right coronary artery (RCA) ...
HeartNews - Philippine Heart Association
HeartNews - Philippine Heart Association

... the field of cardiology needs. But the greater challenge is how to involve and obtain the support of the national government, or at least NGOs and interested parties perhaps, in conducting these investigations and researches that will provide data needed to formulate recommendations of national ...
Performance Measures ACC/AHA 2016 Prevention of Sudden
Performance Measures ACC/AHA 2016 Prevention of Sudden

... development (1) and to ensure that the measures developed are aligned with ACC/AHA clinical guidelines. The writing committees also are charged with constructing measures that maximally capture important aspects of care quality, including timeliness, safety, effectiveness, efficiency, equity, and pa ...
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Electrocardiography



Electrocardiography (ECG or EKG*) is the process of recording the electrical activity of the heart over a period of time using electrodes placed on a patient's body. These electrodes detect the tiny electrical changes on the skin that arise from the heart muscle depolarizing during each heartbeat.In a conventional 12 lead ECG, ten electrodes are placed on the patient's limbs and on the surface of the chest. The overall magnitude of the heart's electrical potential is then measured from twelve different angles (""leads"") and is recorded over a period of time (usually 10 seconds). In this way, the overall magnitude and direction of the heart's electrical depolarization is captured at each moment throughout the cardiac cycle. The graph of voltage versus time produced by this noninvasive medical procedure is referred to as an electrocardiogram (abbreviated ECG or EKG).During each heartbeat, a healthy heart will have an orderly progression of depolarization that starts with pacemaker cells in the sinoatrial node, spreads out through the atrium, passes through the atrioventricular node down into the bundle of His and into the Purkinje fibers spreading down and to the left throughout the ventricles. This orderly pattern of depolarization gives rise to the characteristic ECG tracing. To the trained clinician, an ECG conveys a large amount of information about the structure of the heart and the function of its electrical conduction system. Among other things, an ECG can be used to measure the rate and rhythm of heartbeats, the size and position of the heart chambers, the presence of any damage to the heart's muscle cells or conduction system, the effects of cardiac drugs, and the function of implanted pacemakers.
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