Fiber Types and Myosin Types in Human Atrial and Ventricular
... of myosin exist in the human atrium, each myosin form being histochemically related to either a- or /3-like ventricular myosin heavy chains. In contrast, there was no direct correspondence between the two experimental approaches in human ventricles, and it is postulated that at least three distinct ...
... of myosin exist in the human atrium, each myosin form being histochemically related to either a- or /3-like ventricular myosin heavy chains. In contrast, there was no direct correspondence between the two experimental approaches in human ventricles, and it is postulated that at least three distinct ...
The Fontan circulation after 45 years: update in
... Hospital survival has markedly improved with a reduction in mortality to 1%–2%. In the last couple of years, despite major efforts, ...
... Hospital survival has markedly improved with a reduction in mortality to 1%–2%. In the last couple of years, despite major efforts, ...
Chronic measurement of left ventricular pressure in freely moving rats
... were given subcutaneously before the beginning of surgery. LVP Sensor Implantation Groups A and B. A transdiaphragmatic approach was adopted with the pressure sensor placed in the LV and the telemeter body implanted in the abdomen. A 2.5-cm abdominal midline incision was made in the skin starting fr ...
... were given subcutaneously before the beginning of surgery. LVP Sensor Implantation Groups A and B. A transdiaphragmatic approach was adopted with the pressure sensor placed in the LV and the telemeter body implanted in the abdomen. A 2.5-cm abdominal midline incision was made in the skin starting fr ...
Department of Biomedical Engineering
... forces are applied. Translation and rotation can appear even though the distance remains and thus no deformations occur. The deformations in the cardiac wall are elastic, meaning that once the forces are no longer applied the body returns to its former reference state. Strain describes deformation a ...
... forces are applied. Translation and rotation can appear even though the distance remains and thus no deformations occur. The deformations in the cardiac wall are elastic, meaning that once the forces are no longer applied the body returns to its former reference state. Strain describes deformation a ...
Left Ventricular Volume and Evaluation of Heart Murmurs
... So it is best heard in the pulmonic area (upper left sternal border). Note that heart valves are all normal in ASD. The murmur is quite weak and often may not be detectible. Also note that at times there may also be audible (low pitched) murmurs due to higher tricuspid flow murmur in diastole. ...
... So it is best heard in the pulmonic area (upper left sternal border). Note that heart valves are all normal in ASD. The murmur is quite weak and often may not be detectible. Also note that at times there may also be audible (low pitched) murmurs due to higher tricuspid flow murmur in diastole. ...
A guide to Automated External Defibrillators (AEDs)
... medical services able to attend and provide defibrillation early enough, and the best way of ensuring prompt defibrillation is for someone nearby to use an AED to deliver the shock that can often save a life. ...
... medical services able to attend and provide defibrillation early enough, and the best way of ensuring prompt defibrillation is for someone nearby to use an AED to deliver the shock that can often save a life. ...
Biventricular Pacing in Patients with Bradycardia and Normal
... Downloaded from www.nejm.org on November 15, 2009 . For personal use only. No other uses without permission. Copyright © 2009 Massachusetts Medical Society. All rights reserved. ...
... Downloaded from www.nejm.org on November 15, 2009 . For personal use only. No other uses without permission. Copyright © 2009 Massachusetts Medical Society. All rights reserved. ...
UTILISATION OF CARDIAC COMPUTED TOMOGRAPHY
... the full application and drawbacks of this imaging tool to protect the best interest of our patients. Research in the field of CCT has progressed tremendously. From looking for evidence of stenosis in the coronary vessels, plaque characterisation and vulnerability, we can now look at the haemodynami ...
... the full application and drawbacks of this imaging tool to protect the best interest of our patients. Research in the field of CCT has progressed tremendously. From looking for evidence of stenosis in the coronary vessels, plaque characterisation and vulnerability, we can now look at the haemodynami ...
A guide to Automated External Defibrillators (AEDs)
... medical services able to attend and provide defibrillation early enough, and the best way of ensuring prompt defibrillation is for someone nearby to use an AED to deliver the shock that can often save a life. ...
... medical services able to attend and provide defibrillation early enough, and the best way of ensuring prompt defibrillation is for someone nearby to use an AED to deliver the shock that can often save a life. ...
2016 ACC/AHA/HFSA Focused Update on New Pharmacological
... Evidence (LOE) are derived independently of each other according to established criteria. The COR indicates the strength of recommendation, encompassing the estimated magnitude and certainty of benefit of a clinical action in proportion to risk. The LOE rates the quality of scientific evidence suppo ...
... Evidence (LOE) are derived independently of each other according to established criteria. The COR indicates the strength of recommendation, encompassing the estimated magnitude and certainty of benefit of a clinical action in proportion to risk. The LOE rates the quality of scientific evidence suppo ...
Animal models in the study of myocardial ischaemia and ischaemic
... These methods have the disadvantage that control of blood flow is difficult and requires continuous measurement of blood flow with flow probes or the use of microspheres at intervals. In order to circumvent large variations in flow (e.g. by changes in perfusion pressure or movement of the occlusion ...
... These methods have the disadvantage that control of blood flow is difficult and requires continuous measurement of blood flow with flow probes or the use of microspheres at intervals. In order to circumvent large variations in flow (e.g. by changes in perfusion pressure or movement of the occlusion ...
Assessment and classification of patients with - Heart
... Cardiac troponin is the only recommended biomarker for the detection of myocardial necrosis, and it is integral to the diagnostic criteria for myocardial infarction.1 Our ability to accurately measure cardiac troponin has improved through the development of more sensitive assays, with the latest gen ...
... Cardiac troponin is the only recommended biomarker for the detection of myocardial necrosis, and it is integral to the diagnostic criteria for myocardial infarction.1 Our ability to accurately measure cardiac troponin has improved through the development of more sensitive assays, with the latest gen ...
A guide to Automated External Defibrillators (AEDs)
... medical services able to attend and provide defibrillation early enough, and the best way of ensuring prompt defibrillation is for someone nearby to use an AED to deliver the shock that can often save a life. The term ‘heart attack’ is often used to refer to SCA, but this is incorrect. A heart attac ...
... medical services able to attend and provide defibrillation early enough, and the best way of ensuring prompt defibrillation is for someone nearby to use an AED to deliver the shock that can often save a life. The term ‘heart attack’ is often used to refer to SCA, but this is incorrect. A heart attac ...
cellular update From syncitium to regulated pump: a cardiac muscle
... Ca2⫹ can enter the cell through reverse-mode Na⫹/Ca2⫹ exchanger (NCX) activity. The diagram shown in Fig. 1B can also be used to illustrate the point that Ca2⫹ is required to activate the myofilaments and does so in a cooperative manner. Again, I stress the point that mechanisms that alter cytosolic ...
... Ca2⫹ can enter the cell through reverse-mode Na⫹/Ca2⫹ exchanger (NCX) activity. The diagram shown in Fig. 1B can also be used to illustrate the point that Ca2⫹ is required to activate the myofilaments and does so in a cooperative manner. Again, I stress the point that mechanisms that alter cytosolic ...
How Harmful is Conventional Right Ventricular Apical Pacing
... cardiac disease, indicators of HF severity, and HF medications. The VEST Study [23] demonstrated that QRS duration was found to be an independent predictor of mortality. Patients with wider QRS (>200 ms) had five times greater mortality risk than those with the narrowest (<90 ms). Resting ECG is a p ...
... cardiac disease, indicators of HF severity, and HF medications. The VEST Study [23] demonstrated that QRS duration was found to be an independent predictor of mortality. Patients with wider QRS (>200 ms) had five times greater mortality risk than those with the narrowest (<90 ms). Resting ECG is a p ...
ACC/AHA/NASPE Guideline for Implantation of Cardiac Pacemakers
... financial implications of new evidence were considered in classifying indications. ...
... financial implications of new evidence were considered in classifying indications. ...
ACC/AHA/NASPE Guideline for Implantation of
... financial implications of new evidence were considered in classifying indications. ...
... financial implications of new evidence were considered in classifying indications. ...
The Relationship Between the Right€Ventricle and its Load
... reduction in stroke volume, with uncoupling and increased wall stress as a consequence. With pressure–volume analysis, we separately describe the changing properties of the pulmonary vascular system and the right ventricle, as well as their coupling, as important concepts for understanding the chang ...
... reduction in stroke volume, with uncoupling and increased wall stress as a consequence. With pressure–volume analysis, we separately describe the changing properties of the pulmonary vascular system and the right ventricle, as well as their coupling, as important concepts for understanding the chang ...
Contractility and ischemic response of hearts from transgenic mice
... does not improve post-ischemic recovery in transgenics. Transgenic hearts also demonstrate a poor recovery following metabolic inhibition. These data are consistent with the hypothesis that sarcolemmal KATP channels are required for development of normal myocardial function, and perturbations of KAT ...
... does not improve post-ischemic recovery in transgenics. Transgenic hearts also demonstrate a poor recovery following metabolic inhibition. These data are consistent with the hypothesis that sarcolemmal KATP channels are required for development of normal myocardial function, and perturbations of KAT ...
Obesity/Metabolic Syndrome
... From a longitudinal section of the LV obtained from the apex to the base through the LV free wall, a pathological score was determined using a previously described approach (please see the online Data Supplement for details).27 The degree of apoptosis was quantified as described previously34 on 5-m ...
... From a longitudinal section of the LV obtained from the apex to the base through the LV free wall, a pathological score was determined using a previously described approach (please see the online Data Supplement for details).27 The degree of apoptosis was quantified as described previously34 on 5-m ...
8951203.pps - MyPACS.net
... In more than 50% of individuals, the first branch of the RCA is the conus artery, unless it (the RCA) has a separate origin directly from the right coronary sinus. The second branches usually consist of the sinoatrial node artery and several anterior branches that supply the free wall of the right v ...
... In more than 50% of individuals, the first branch of the RCA is the conus artery, unless it (the RCA) has a separate origin directly from the right coronary sinus. The second branches usually consist of the sinoatrial node artery and several anterior branches that supply the free wall of the right v ...
The Cardioprotective Effects of Hydrogen Sulfide in Heart
... major risk for sudden death after coronary artery occlusion [41]. The primary causes for I/R-induced arrhythmias are considered to be the endogenous metabolites, such as reactive oxygen species (ROS), calcium, thrombin, and platelet activating factor, produced and accumulated in the myocardium durin ...
... major risk for sudden death after coronary artery occlusion [41]. The primary causes for I/R-induced arrhythmias are considered to be the endogenous metabolites, such as reactive oxygen species (ROS), calcium, thrombin, and platelet activating factor, produced and accumulated in the myocardium durin ...
Stromal interaction molecule 1 is essential for normal cardiac
... frequency and survive into adulthood with no obvious physical differences or changes in body weight. Unbiased gene array analyses on whole heart tissue from 12-wk-old male mice ...
... frequency and survive into adulthood with no obvious physical differences or changes in body weight. Unbiased gene array analyses on whole heart tissue from 12-wk-old male mice ...
time-resolved fluorescence spectroscopy of the heart
... The aim of our study was to investigate the different heart tissues by means of time-resolved fluorescence spectroscopy, and also to determine the number of fluorescing constituents composing the registered steady state fluorescence spectra and to calculate the fractional components of the fluoresce ...
... The aim of our study was to investigate the different heart tissues by means of time-resolved fluorescence spectroscopy, and also to determine the number of fluorescing constituents composing the registered steady state fluorescence spectra and to calculate the fractional components of the fluoresce ...
Electrocardiography
Electrocardiography (ECG or EKG*) is the process of recording the electrical activity of the heart over a period of time using electrodes placed on a patient's body. These electrodes detect the tiny electrical changes on the skin that arise from the heart muscle depolarizing during each heartbeat.In a conventional 12 lead ECG, ten electrodes are placed on the patient's limbs and on the surface of the chest. The overall magnitude of the heart's electrical potential is then measured from twelve different angles (""leads"") and is recorded over a period of time (usually 10 seconds). In this way, the overall magnitude and direction of the heart's electrical depolarization is captured at each moment throughout the cardiac cycle. The graph of voltage versus time produced by this noninvasive medical procedure is referred to as an electrocardiogram (abbreviated ECG or EKG).During each heartbeat, a healthy heart will have an orderly progression of depolarization that starts with pacemaker cells in the sinoatrial node, spreads out through the atrium, passes through the atrioventricular node down into the bundle of His and into the Purkinje fibers spreading down and to the left throughout the ventricles. This orderly pattern of depolarization gives rise to the characteristic ECG tracing. To the trained clinician, an ECG conveys a large amount of information about the structure of the heart and the function of its electrical conduction system. Among other things, an ECG can be used to measure the rate and rhythm of heartbeats, the size and position of the heart chambers, the presence of any damage to the heart's muscle cells or conduction system, the effects of cardiac drugs, and the function of implanted pacemakers.