Repaired tetralogy of Fallot: the roles of cardiovascular magnetic
... unique opportunity to examine the long-term effects of severe chronic PR without the confounding effects of cyanosis, ventricular septal defect, pulmonary stenosis, or the sequelae of cardiac surgery. In a review of 72 such cases reported in the literature [31], Shimazaki et al. found that that the ...
... unique opportunity to examine the long-term effects of severe chronic PR without the confounding effects of cyanosis, ventricular septal defect, pulmonary stenosis, or the sequelae of cardiac surgery. In a review of 72 such cases reported in the literature [31], Shimazaki et al. found that that the ...
The electrophysiology of the atrioventricular node in normal and
... suggesting the most likely site of delay is the AV node. The mechanisms by which this occurs are not fully understood. The purpose of this thesis was to confirm that the abnormal prolongation of AV conduction time originates at the AV node in a rabbit model of LVD due to apical myocardial infarction ...
... suggesting the most likely site of delay is the AV node. The mechanisms by which this occurs are not fully understood. The purpose of this thesis was to confirm that the abnormal prolongation of AV conduction time originates at the AV node in a rabbit model of LVD due to apical myocardial infarction ...
Cardiac Sympathetic Innervation Via the Middle Cervical and
... with funding of the study, and edited and revised the manuscript. Dr. Vaseghi designed and funded the ...
... with funding of the study, and edited and revised the manuscript. Dr. Vaseghi designed and funded the ...
Myosin Types and Fiber Types II. Atrial Myocardium
... specific IgG were obtained by affinity chromatography, and that cross-reactive antibodies were eliminated by absorption with insolubilized ventricular myosin. Similar procedures were used for the preparation of antibodies to bovine ventricular myosin (anti-bVm). Myosin was isolated from the free wal ...
... specific IgG were obtained by affinity chromatography, and that cross-reactive antibodies were eliminated by absorption with insolubilized ventricular myosin. Similar procedures were used for the preparation of antibodies to bovine ventricular myosin (anti-bVm). Myosin was isolated from the free wal ...
Noninvasive Evaluation of Myocardial Ischemia and Left
... The general aim of this thesis was, following the path of the ischemic cascade, to evaluate the feasibility of some new non-invasive techniques for the detection of myocardial ischemia, the extent of infarcted myocardium, and for the quantification of systolic left ventricular function. Reduced long ...
... The general aim of this thesis was, following the path of the ischemic cascade, to evaluate the feasibility of some new non-invasive techniques for the detection of myocardial ischemia, the extent of infarcted myocardium, and for the quantification of systolic left ventricular function. Reduced long ...
Left ventricular diastolic function assessed using Doppler
... diastolic function, most studies have failed to show significant correlations between Doppler derived transmitral velocities and the severity of left ventricular hypertrophy, symptoms, exercise capacity, or mean left atrial pressure in patients with hypertrophic cardiomyopathy.6 7 9 11 12 Convention ...
... diastolic function, most studies have failed to show significant correlations between Doppler derived transmitral velocities and the severity of left ventricular hypertrophy, symptoms, exercise capacity, or mean left atrial pressure in patients with hypertrophic cardiomyopathy.6 7 9 11 12 Convention ...
Right Heart Adaptation to Pulmonary Arterial€Hypertension
... therapy, a smaller proportion of patients will have low–cardiac output syndrome requiring inotropic or vasopressor support (29,30). Although the most common cause of death in patients with PAH is progressive RHF, sudden and unexpected death may also occur (33). In a study by Hoeper et al. (33), sudd ...
... therapy, a smaller proportion of patients will have low–cardiac output syndrome requiring inotropic or vasopressor support (29,30). Although the most common cause of death in patients with PAH is progressive RHF, sudden and unexpected death may also occur (33). In a study by Hoeper et al. (33), sudd ...
PDF
... can be seen in the neonate, but sometimesolder children are diagnosed, after a high blood pressure is detected. When fetal diagnosis of coarctation is made or suspected, delivery must be foreseen in a centre where specialised cardiac care can take place. intravenous Prostaglandines type 1 are used n ...
... can be seen in the neonate, but sometimesolder children are diagnosed, after a high blood pressure is detected. When fetal diagnosis of coarctation is made or suspected, delivery must be foreseen in a centre where specialised cardiac care can take place. intravenous Prostaglandines type 1 are used n ...
Heart to Heart: Inherited Cardiovascular
... for some conditions within existing services. In addition, while most services include an effective range of professional roles, they are often not working as a truly multidisciplinary team. The relative weight given to different areas of specialist expertise is variable and, in many services, genet ...
... for some conditions within existing services. In addition, while most services include an effective range of professional roles, they are often not working as a truly multidisciplinary team. The relative weight given to different areas of specialist expertise is variable and, in many services, genet ...
Echocardiographic Measurement of Right Ventricular Wall Thickness
... from the same patient, which clearly revealed the right ventricular wall. In both panels, the echo from the epicardium of the right ventricular wall was denser than that from the endocardium and the effusion fluid separated the epicardium from the pericardium throughout the whole cardiac phase. The ...
... from the same patient, which clearly revealed the right ventricular wall. In both panels, the echo from the epicardium of the right ventricular wall was denser than that from the endocardium and the effusion fluid separated the epicardium from the pericardium throughout the whole cardiac phase. The ...
Importance of Atrial Flutter Isthmus in Postoperative Intra
... placed to record from the coronary sinus, the bundle of His, and the right ventricle. In addition, when possible, a 20-pole halo electrode catheter was placed in the right atrium such that it encircled the tricuspid valve, with the distal pair of electrodes near the os of the coronary sinus. All int ...
... placed to record from the coronary sinus, the bundle of His, and the right ventricle. In addition, when possible, a 20-pole halo electrode catheter was placed in the right atrium such that it encircled the tricuspid valve, with the distal pair of electrodes near the os of the coronary sinus. All int ...
Pulmonary venous flow by doppler echocardiography: revisited 12
... Figure 2. Pulmonary venous flow (PVF) (top) and mitral inflow (bottom) velocity profiles recorded by transesophageal echocardiography in patients with left ventricular diastolic dysfunction. (A) Relaxation abnormality pattern. The peak pulmonary venous systolic velocity (S) increased. The peak pulmo ...
... Figure 2. Pulmonary venous flow (PVF) (top) and mitral inflow (bottom) velocity profiles recorded by transesophageal echocardiography in patients with left ventricular diastolic dysfunction. (A) Relaxation abnormality pattern. The peak pulmonary venous systolic velocity (S) increased. The peak pulmo ...
Author`s final copy - Canada`s Michael Smith Genome Sciences
... phenotype [19]. The mesenchymal cells invade the ECM and populate the cardiac cushions [20,21]. The OFT, which will form the SL valves, develops similarly with the exception that neural crest cells migrate and contribute to the OFT cushions (reviewed in [22]). Following invasion into the cardiac cus ...
... phenotype [19]. The mesenchymal cells invade the ECM and populate the cardiac cushions [20,21]. The OFT, which will form the SL valves, develops similarly with the exception that neural crest cells migrate and contribute to the OFT cushions (reviewed in [22]). Following invasion into the cardiac cus ...
Electrophysiological Actions of Diphenylhydantoin on Rabbit Atria
... and action potentials were recorded from these preparations with glass microelectrodes at stimulation rates ranging from 0.2 to 3/sec. DPH had little or no effect on the relationship between extracellular [K + ] and membrane resting potential. Action potential overshoot was generally decreased by 5 ...
... and action potentials were recorded from these preparations with glass microelectrodes at stimulation rates ranging from 0.2 to 3/sec. DPH had little or no effect on the relationship between extracellular [K + ] and membrane resting potential. Action potential overshoot was generally decreased by 5 ...
6 The Coronary System and Associated Medical Devices
... These procedures involve the cannulation and catheterization of the coronary sinus, which allows access to the coronary venous network. More specifically, biventricular pacing procedures have become quite common (10-18) and have elicited greater interest in the coronary venous system. Typically, dur ...
... These procedures involve the cannulation and catheterization of the coronary sinus, which allows access to the coronary venous network. More specifically, biventricular pacing procedures have become quite common (10-18) and have elicited greater interest in the coronary venous system. Typically, dur ...
Adult Heart Murmurs - American Academy of Family Physicians
... and explain the pathology of heart murmurs to patients. 3. Evaluate diagnostic factors in patients with suspected heart murmurs using cost-effective cardiac testing. 4. Coordinate referral and follow-up to a cardiologist for patients with a pathologic cardiac examination, or who has cardiac symptoms ...
... and explain the pathology of heart murmurs to patients. 3. Evaluate diagnostic factors in patients with suspected heart murmurs using cost-effective cardiac testing. 4. Coordinate referral and follow-up to a cardiologist for patients with a pathologic cardiac examination, or who has cardiac symptoms ...
Intracellular Ca waves, afterdepolarizations, and
... propagate into a region where a short APD occurred, whereas block occurs in a refractory region following a long APD. Triggered waves can lead to a heterogeneous distribution of APD, since they occur during an AP and therefore significantly change the APD on a beat-to-beat basis. Thus, if a region o ...
... propagate into a region where a short APD occurred, whereas block occurs in a refractory region following a long APD. Triggered waves can lead to a heterogeneous distribution of APD, since they occur during an AP and therefore significantly change the APD on a beat-to-beat basis. Thus, if a region o ...
chronic congestive heart failure.
... were corrected to 20° C and to water as a solvent by the standard formula (15). A value of 0.728 was used for the partial specific volume of myosin. Diffusion measurements were made in an Aminco model B electrophoresis apparatus at 6° C, using carefully selected cells and the Raleigh interferometer ...
... were corrected to 20° C and to water as a solvent by the standard formula (15). A value of 0.728 was used for the partial specific volume of myosin. Diffusion measurements were made in an Aminco model B electrophoresis apparatus at 6° C, using carefully selected cells and the Raleigh interferometer ...
Impacts of aortic stenosis and hypertension on left ventricular
... double (i.e. valvular and vascular) pressure overload, which results in subsequent wall volume hypertrophy. From a clinical standpoint, it is difficult to separate the respective contributions of aortic stenosis and systemic hypertension to left ventricular burden and patient’s symptoms and thus to p ...
... double (i.e. valvular and vascular) pressure overload, which results in subsequent wall volume hypertrophy. From a clinical standpoint, it is difficult to separate the respective contributions of aortic stenosis and systemic hypertension to left ventricular burden and patient’s symptoms and thus to p ...
Articles in PresS. Am J Physiol Heart Circ Physiol (November 20
... processes in response to long-term ischemic injuries, such as permanent MI. Due to rapidly ...
... processes in response to long-term ischemic injuries, such as permanent MI. Due to rapidly ...
Rho-Kinase Activation in Patients With Heart Failure - J
... disease. The aim of this study was to determine whether the activity of Rho-kinase, which has been identified as an important therapeutic target of cardiovascular disease, is enhanced in HF patients. Methods and Results: Total and phosphorylated forms of myosin binding subunit (t-MBS and p-MBS), a ...
... disease. The aim of this study was to determine whether the activity of Rho-kinase, which has been identified as an important therapeutic target of cardiovascular disease, is enhanced in HF patients. Methods and Results: Total and phosphorylated forms of myosin binding subunit (t-MBS and p-MBS), a ...
Electrocardiography
Electrocardiography (ECG or EKG*) is the process of recording the electrical activity of the heart over a period of time using electrodes placed on a patient's body. These electrodes detect the tiny electrical changes on the skin that arise from the heart muscle depolarizing during each heartbeat.In a conventional 12 lead ECG, ten electrodes are placed on the patient's limbs and on the surface of the chest. The overall magnitude of the heart's electrical potential is then measured from twelve different angles (""leads"") and is recorded over a period of time (usually 10 seconds). In this way, the overall magnitude and direction of the heart's electrical depolarization is captured at each moment throughout the cardiac cycle. The graph of voltage versus time produced by this noninvasive medical procedure is referred to as an electrocardiogram (abbreviated ECG or EKG).During each heartbeat, a healthy heart will have an orderly progression of depolarization that starts with pacemaker cells in the sinoatrial node, spreads out through the atrium, passes through the atrioventricular node down into the bundle of His and into the Purkinje fibers spreading down and to the left throughout the ventricles. This orderly pattern of depolarization gives rise to the characteristic ECG tracing. To the trained clinician, an ECG conveys a large amount of information about the structure of the heart and the function of its electrical conduction system. Among other things, an ECG can be used to measure the rate and rhythm of heartbeats, the size and position of the heart chambers, the presence of any damage to the heart's muscle cells or conduction system, the effects of cardiac drugs, and the function of implanted pacemakers.