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EXERCISE 7 Cellular Respiration
EXERCISE 7 Cellular Respiration

... Name 2 molecules that are used as the final electron acceptor if oxygen is not available. State the products formed in each case. ...
Oxidation
Oxidation

... Pyruvate to Ethanol Yeasts and several other organisms regenerate NAD+ by this two-step pathway: • Decarboxylation of pyruvate to acetaldehyde. ...
Metabolism of fat File
Metabolism of fat File

... • Five steps are involved and each step involves acy1CoA derivatives catalyzed by separate enzymes, utilizes NAD+ and FAD as coenzymes, and generates ATP. • Fatty acid oxidation is an aerobic process, requiring the presence of oxygen. ...
A generalized stoichiometric model of C3, C2, C2
A generalized stoichiometric model of C3, C2, C2

Lysis of Human Monocytic Leukemia Cells by
Lysis of Human Monocytic Leukemia Cells by

... these cells by ATP (data not shown). IFN-y-treated THP- 1 cells, however, rapidly released the radioactivity into the supernatant fluids, which was maximal after the first 2 hours. The percent of "Cr released after 24 hours was not significantly different from the percent released at 2 hours. Thus, ...
MCAT 2015
MCAT 2015

... Description  of  fatty  acids  (BC)   Digestion,  mobilization,  and  transport  of  fats   Oxidation  of  fatty  acids     o Saturated  fats   o Unsaturated  fats   Ketone  bodies  (BC)   Anabolism  of  fats  (BIO)   Non-­‐template  synthesis: ...
Cellular Respiration
Cellular Respiration

... Lactic acid fermentation can supply enough ATP to last about 90 seconds. However, extra oxygen is required to get rid of the lactic acid produced. Following intense exercise, a person will huff and puff for several minutes in order to pay back the built-up “oxygen debt” and clear the lactic acid fro ...
Fatty acid catabolism leture2-3
Fatty acid catabolism leture2-3

... This condition is called “acidosis” which can lead to com or death. High concentration of ketone bodies in blood and urine is referred as “ketosis”. Due to high concentration of acetoacetate, which is converted to acetone, the breath and urine of theuntreated diabetic ...
answer key - chem.uwec.edu
answer key - chem.uwec.edu

... • Describe the primary purpose of the citric acid cycle. (Question 6) • Discuss the various roles played by the citric acid cycle in cellular metabolism (Question 6) • Describe the steps in the citric acid cycle. (Question 3) • Describe the structures of the intermediates in citric acid cycle. (Ques ...
Isotope-Exchange Evidence that Glucose 6
Isotope-Exchange Evidence that Glucose 6

... with the MgATP concentration, at glucose 6-phosphate concentrations above 1 mM. This behaviour does not permit glucose 6-phosphate to act only as a normal product inhibitor. Instead, it seems to require glucose 6-phosphate to act as an allosteric inhibitor and for a second site for binding of MgATP ...
Thermodynamic constraints shape the structure of carbon fixation
Thermodynamic constraints shape the structure of carbon fixation

WSC` 06 MS Word Template
WSC` 06 MS Word Template

... This is the simplest model for the biomolecular reaction network that retains the basic features of the system. As a consequence of the fact that the transcription and translation reactions are described at the conceptual level as lumped macro-reactions, this model represents an approximation to the ...
Introduction to Lipid Metabolism Roles of Lipids - Rose
Introduction to Lipid Metabolism Roles of Lipids - Rose

... Because layers of lipids are good insulators, and because adipose tissue has limited metabolic activity, fat stores can reduce the exchange of heat between an organism and its environment. This insulation is important for mammals living in cold climates, and is especially important for marine mammal ...
Chapter 23 Gluconeogenesis Gluconeogenesis, con`t.
Chapter 23 Gluconeogenesis Gluconeogenesis, con`t.

... • Brain and muscle consume most of the glucose. • Liver and kidney are the main sites of gluconeogenesis. • Substrates include pyruvate, lactate, glycerol, most amino acids, and all TCA intermediates. • Fatty acids cannot be converted to glucose in animals. • (They can in plants because of the glyox ...
Gluconeogenesis
Gluconeogenesis

... -Essential in mammals because the brain, nervous system, erythrocytes, tests and medulla require glucose from blood as their major fuel source - Important precursors of the glucose: Lactate, pyruvate, glycerol and back bone of certain amino acids - Fasting requires all the glucose to be synthesized ...
The role of mitochondrial hexokinase II in ischemia - UvA-DARE
The role of mitochondrial hexokinase II in ischemia - UvA-DARE

... prolonged period of ischemia. This heterogeneity of cell death occurring should be kept in mind when judging the effects of I/R in the complete heart. Furthermore, besides the loss of flow, the recurrence of blood flow has also been recognized as detrimental as it also induces cell death, called rep ...
Simulating the physiology of athletes during endurance
Simulating the physiology of athletes during endurance

... with oxygen is converted to external work. The remainder of the energy is converted to heat, which is transported from the muscle by thermal conduction and circulatory convection. The blood also delivers oxygen and carbon substrates to the muscle and carries away the breakdown products, such as carb ...
Lecture 3: Prokaryotic and Eukaryotic Cells
Lecture 3: Prokaryotic and Eukaryotic Cells

... components (complex I to complex V) are integral proteins, present in the inner membrane of mitochondria. During metabolic reactions such as glycolysis, Kreb’s cycle [metabolic reaction are discussed later] produces large amount of reducing equivalent in the form of NADH2 and FADH2. Electron transpo ...
Biosynthesis of glucose – gluconeogenesis
Biosynthesis of glucose – gluconeogenesis

... Regulation of the Enzymes Amount by Hormones Hormones affect gene expression primarily by changing the rate of transcription. Insulin, which rises subsequent to eating, stimulates the expression of phosphofructokinase and pyruvate kinase. Glucagon, which rises during starvation, inhibits the expres ...
Peroxisomal oxidation of fatty acids
Peroxisomal oxidation of fatty acids

... Utilization of FA for oxidation and generation of ATP is achieved in the following three steps; 1. beta-oxidation of fatty acid chain yielding acaty-CoA. 2. Entry of actyl-CoA in citric acid cycle yielding NADH, FADH2 and GTP. 3. Utilization of NADH and FADH2 in ...
CHAPTER 20 - AMINO ACID METABOLISM Introduction Amino acid
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Alteration by site-directed mutagenesis of the
Alteration by site-directed mutagenesis of the

... hydroxylapatite and heparin-agarose contained the RecB-K29Q, RecC, and RecD proteins, and a single major contaminant (Fig. 2). Analysis of the gel shown in Fig. 2 by densitometry showed that the contaminant was about 70% of the total protein in the preparation. The protein concentration in this samp ...
Regents Biology
Regents Biology

... Regents Biology ...
mechanism of photosynthesis
mechanism of photosynthesis

... In cyclic photophosphorylation the electrons lost by PS-I is cycled back to it, whereas in non-cyclic photophosphorylation, one electron is lost it doesn’t enter into PS-II, thus it involves both PS-I and PS-II. (i) Non-cyclic photophosphorylation : Hill and Bendal (1960) and Robinowitch and Govindj ...
No Slide Title
No Slide Title

...  SAST test (aspartate …, or GOT)  SCK test (serum creatine kinase) ...
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Adenosine triphosphate



Adenosine triphosphate (ATP) is a nucleoside triphosphate used in cells as a coenzyme often called the ""molecular unit of currency"" of intracellular energy transfer.ATP transports chemical energy within cells for metabolism. It is one of the end products of photophosphorylation, cellular respiration, and fermentation and used by enzymes and structural proteins in many cellular processes, including biosynthetic reactions, motility, and cell division. One molecule of ATP contains three phosphate groups, and it is produced by a wide variety of enzymes, including ATP synthase, from adenosine diphosphate (ADP) or adenosine monophosphate (AMP) and various phosphate group donors. Substrate-level phosphorylation, oxidative phosphorylation in cellular respiration, and photophosphorylation in photosynthesis are three major mechanisms of ATP biosynthesis.Metabolic processes that use ATP as an energy source convert it back into its precursors. ATP is therefore continuously recycled in organisms: the human body, which on average contains only 250 grams (8.8 oz) of ATP, turns over its own body weight equivalent in ATP each day.ATP is used as a substrate in signal transduction pathways by kinases that phosphorylate proteins and lipids. It is also used by adenylate cyclase, which uses ATP to produce the second messenger molecule cyclic AMP. The ratio between ATP and AMP is used as a way for a cell to sense how much energy is available and control the metabolic pathways that produce and consume ATP. Apart from its roles in signaling and energy metabolism, ATP is also incorporated into nucleic acids by polymerases in the process of transcription. ATP is the neurotransmitter believed to signal the sense of taste.The structure of this molecule consists of a purine base (adenine) attached by the 9' nitrogen atom to the 1' carbon atom of a pentose sugar (ribose). Three phosphate groups are attached at the 5' carbon atom of the pentose sugar. It is the addition and removal of these phosphate groups that inter-convert ATP, ADP and AMP. When ATP is used in DNA synthesis, the ribose sugar is first converted to deoxyribose by ribonucleotide reductase.ATP was discovered in 1929 by Karl Lohmann, and independently by Cyrus Fiske and Yellapragada Subbarow of Harvard Medical School, but its correct structure was not determined until some years later. It was proposed to be the intermediary molecule between energy-yielding and energy-requiring reactions in cells by Fritz Albert Lipmann in 1941. It was first artificially synthesized by Alexander Todd in 1948.
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