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tib4handout
tib4handout

... 3. Natural Killer Cells: NK cells may directly lyse some virus-infected cells without prior sensitization to the virus by failing to recognize the cell as normal self. Viruses can sometimes interfere with the ability of the infected cell to express MHC-I molecules. Without the signal from the kille ...
Chapter 43 - The Immune System
Chapter 43 - The Immune System

... Focus Topics Immunological responses to pathogens, toxins, and allergens  Vertebrate immune systems have nonspecific and nonheritable defense mechanisms against pathogens  The mammalian immune system includes two types of specific responses: cell mediated and humoral  In the cell-mediated respon ...
Course Objectives - Geisel School of Medicine
Course Objectives - Geisel School of Medicine

... Course  Objective Describe  the  cells,  products,  and  effector  responses  of  the  immune  system Describe  an  immune  response  from  initiation  to  resolution Describe  T  and  B  cell  receptor  diversity  and  antigen  recognition Expla ...
VMB 673 Comparative Immunology Syllabus 2013 Revised Cat 2
VMB 673 Comparative Immunology Syllabus 2013 Revised Cat 2

... Course Content: (Subjects covered in outline form if known or appropriate) Limit 1 page per 2 credit hours, list individually any topic given over 1hour of contact time. NOTE: Each topic below will be explored in two ways: 1. A brief introduction into the topic similar to an introductory immunology ...
Mr. B: Health 2 Chapter 23 Lesson 3 Notes Today`s Objectives
Mr. B: Health 2 Chapter 23 Lesson 3 Notes Today`s Objectives

... ______________________ membranes form a ____________________ lining for your mouth, nose, and many other parts of your body. These membranes ________________ pathogens and _________________ them to other parts of the body for disposal. ...
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08_Fact_Path_Vir_2_2014

... Damage as a result of defence reactions b) Injuries caused by specific immune reaction (immunopathological consequences of hypersensitivity) ...
Immunology: Specific Immunity
Immunology: Specific Immunity

... Dual Nature of the immune system • Humoral and cell mediated – Humoral refers to body fluids • Specifically antibodies: protein molecules dissolved in blood, body fluids, and secretions. • B lymphocytes are the source of antibodies – Cell mediated refers to the direct involvement of cells to attack ...
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20-Professional-APC

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... Innate immune effector mechanisms – Complement • Complement: – complex group of plasma proteins that are pre-formed (not made in response to infection) – found in serum and body fluids – produced mainly by liver cells – can be thought of as a form of innate humoral immunity • Activation of complemen ...
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... Antigen-presenting cells are functionally-defined cells that are able initiate adaptive immune responses by presenting antigen to T cells. Major APCs are dendritic cells (DCs), which are found throughout the body – however macrophages and B cells may also serve as APCs, with the former providing an ...
Document
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... B Cells: these cells do not travel to the thymus after they have been made like T cells do. They travel in the blood stream "looking" for foreign antigens. When it locates an antigen, it splits into plasma cells which produce antibodies. ...
The Immune System
The Immune System

... Monocytes change into these as they leave the blood and enter the tissues. – These are phagocytic cells – Can eat many (100’s) of pathogens and survive. – Eat old blood cells and bits of dead tissue – Stimulate the immune response. • Increase production of white blood cells in bone marrow ...
What is immunology - British Society for Immunology
What is immunology - British Society for Immunology

... Antigen-presenting cells are functionally-defined cells that are able too initiate adaptive immune responses by presenting antigen to T cells. Major APCs are dendritic cells (DCs), which are found throughout the body – however macrophages and B cells may also serve as APCs, with the former providing ...
What is immunology - British Society for Immunology
What is immunology - British Society for Immunology

... Antigen-presenting cells are functionally-defined cells that are able too initiate adaptive immune responses by presenting antigen to T cells. Major APCs are dendritic cells (DCs), which are found throughout the body – however macrophages and B cells may also serve as APCs, with the former providing ...
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... _______4. The inflammatory response is part of the body’s first line of defense. _______5. Leukocytes are white blood cells that fight infections and get rid of debris. _______6. The second line of defense attacks pathogens that manage to enter the body. _______7. The first line of defense includes ...
Slide 1
Slide 1

... lysozyme, collagenase, and elastase) that do not stain strongly with either basic or acidic dyes and azurophilic granules (lysosomes containing enzymes and other microbicidal substances, including defensins and cathelicidins) Production of neutrophils is stimulated by granulocyte colony-stimulating ...
No Slide Title - Pegasus @ UCF
No Slide Title - Pegasus @ UCF

... Table 15.5 Immunology Review Immunoglobulins IgC most abundant Ig of internal body fluids, particularly extravascular. Where they combat micro-organisms and their toxins IgA major Ig insero-mucus secretions where it defends external body surfaces IgM very effective agglutinator; produced early in i ...
1 - Lone Star College
1 - Lone Star College

... When B cells encounter an antigen they are activated to divide many times Plasma cells – mature B cell that produces antibodies ...
Ch. 43 The Immune System notes
Ch. 43 The Immune System notes

... • Acquired immunodeficiency develops later in life and results from exposure to chemical and biological agents • Acquired immunodeficiency syndrome (AIDS) is caused by a virus ...
Unraveling the Tissue Specific Antigen Presentation That Results in
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... to the therapeutic protein is a key requirement for successful therapy. The liver has a distinctive composition and microenvironment that favors the development of immune tolerance above that of immunity. Antigens expressed in situ are more likely to be tolerogenic than those expressed in the periph ...
tib3handout_me
tib3handout_me

... Effects on tissues on the implant and implant on the tissues are both important factors. Most result from alterations of normal physiological processes for example immunity, inflammation and blood coagulation. These are host defence mechanisms which protect us from dangerous external threats such as ...
The Immune System - John Burroughs Middle School
The Immune System - John Burroughs Middle School

... stemper in dogs, don’t harm humans • Vice versa, some viruses, such as HIV, make humans ill, but not cats or dogs ...
Lecture7_8 - Welcome to people.pharmacy.purdue.edu!
Lecture7_8 - Welcome to people.pharmacy.purdue.edu!

Chapter 43: The Immune System
Chapter 43: The Immune System

... Skin, mucus, ciliated cells, tears, urine flow, coughing, sneezing, ear wax ...
Mechanism of delayed hypersensitivity
Mechanism of delayed hypersensitivity

... • ACAID is initiated by an antigen-specific signal generated within the anterior chamber via intraocular dendritic cells and macrophages. • Under the influence of immunoregulatory factors (____________________________________) in aqueous humor, these cells: – capture antigen – process it uniquely – ...
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Immune system



The immune system is a system of many biological structures and processes within an organism that protects against disease. To function properly, an immune system must detect a wide variety of agents, known as pathogens, from viruses to parasitic worms, and distinguish them from the organism's own healthy tissue. In many species, the immune system can be classified into subsystems, such as the innate immune system versus the adaptive immune system, or humoral immunity versus cell-mediated immunity.Pathogens can rapidly evolve and adapt, and thereby avoid detection and neutralization by the immune system; however, multiple defense mechanisms have also evolved to recognize and neutralize pathogens. Even simple unicellular organisms such as bacteria possess a rudimentary immune system, in the form of enzymes that protect against bacteriophage infections. Other basic immune mechanisms evolved in ancient eukaryotes and remain in their modern descendants, such as plants and insects. These mechanisms include phagocytosis, antimicrobial peptides called defensins, and the complement system. Jawed vertebrates, including humans, have even more sophisticated defense mechanisms, including the ability to adapt over time to recognize specific pathogens more efficiently. Adaptive (or acquired) immunity creates immunological memory after an initial response to a specific pathogen, leading to an enhanced response to subsequent encounters with that same pathogen. This process of acquired immunity is the basis of vaccination.Disorders of the immune system can result in autoimmune diseases, inflammatory diseases and cancer.Immunodeficiency occurs when the immune system is less active than normal, resulting in recurring and life-threatening infections. In humans, immunodeficiency can either be the result of a genetic disease such as severe combined immunodeficiency, acquired conditions such as HIV/AIDS, or the use of immunosuppressive medication. In contrast, autoimmunity results from a hyperactive immune system attacking normal tissues as if they were foreign organisms. Common autoimmune diseases include Hashimoto's thyroiditis, rheumatoid arthritis, diabetes mellitus type 1, and systemic lupus erythematosus. Immunology covers the study of all aspects of the immune system.
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