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Medical technologies
Medical technologies

... When doctors give transplants or grafts they have to be careful to avoid rejection reactions from the recipient’s immune system. The blood contains special cells called leukocytes or white blood cells which are responsible for Some white blood cells called phagocytes fight disease by Other white blo ...
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免疫与感染性疾病( Immunity and infectious diseases )

... more responsible for infection diseases. immunity possesses specificity • Active immunity: The form of immunity that is induced by exposure to a foreign antigen, in which the immunized individual plays an active role in responding to the antigen • Passive immunity :The form of immunity that is estab ...
Chapter 24 powerpoint file
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... – Class I MHC molecules (nucleated body cells) expose foreign proteins – Activity enhanced by CD8 surface protein present on most cytotoxic T cells (similar to CD4 and class II MHC) ...
Elisa kits Manual
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... with clinical activity. Their presence is also associated with active lupus and usually with immune complex glomerulo-nephritis. Antibodies to ds-DNA are directed against the phosphate-deoxyribose backbone of the DNA molecule, and appear to be generated due to preferential activation of specific B c ...
Course of Immunology
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... There are two types of T-cells, T-helper (Th) cells and T-cytotoxic (Tc) cells. Th-cells secrete cytokines (chemical regulators of the immune response, see below), which activate various phagocytic cells, B-cells, Tc-cells, macrophages and various other cells. Tc-cells do not secrete cytokines but h ...
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Cystatin 9: the key to effective treatment for bacterial lung disease?

... can analyse the signalling pathways and secretions from the same cell type to identify what types of inflammatory cytokines/ factors are produced as well as how much they are producing. The level of bacterialinduced inflammation can be correlated with cell damage by microscopy analysis of cell histo ...
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Science News Discarded Immune Cells Induce the

... clearance of neutrophils from the body stimulates the release of hematopoietic stem cells from the bone marrow into the bloodstream, according to a report published today in the journal Cell. Share This: Neutrophils are leukocytes (white blood cells) that defend the body against attack from bacteria ...
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Polyclonal B cell response



Polyclonal B cell response is a natural mode of immune response exhibited by the adaptive immune system of mammals. It ensures that a single antigen is recognized and attacked through its overlapping parts, called epitopes, by multiple clones of B cell.In the course of normal immune response, parts of pathogens (e.g. bacteria) are recognized by the immune system as foreign (non-self), and eliminated or effectively neutralized to reduce their potential damage. Such a recognizable substance is called an antigen. The immune system may respond in multiple ways to an antigen; a key feature of this response is the production of antibodies by B cells (or B lymphocytes) involving an arm of the immune system known as humoral immunity. The antibodies are soluble and do not require direct cell-to-cell contact between the pathogen and the B-cell to function.Antigens can be large and complex substances, and any single antibody can only bind to a small, specific area on the antigen. Consequently, an effective immune response often involves the production of many different antibodies by many different B cells against the same antigen. Hence the term ""polyclonal"", which derives from the words poly, meaning many, and clones (""Klon""=Greek for sprout or twig); a clone is a group of cells arising from a common ""mother"" cell. The antibodies thus produced in a polyclonal response are known as polyclonal antibodies. The heterogeneous polyclonal antibodies are distinct from monoclonal antibody molecules, which are identical and react against a single epitope only, i.e., are more specific.Although the polyclonal response confers advantages on the immune system, in particular, greater probability of reacting against pathogens, it also increases chances of developing certain autoimmune diseases resulting from the reaction of the immune system against native molecules produced within the host.
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