• Study Resource
  • Explore
    • Arts & Humanities
    • Business
    • Engineering & Technology
    • Foreign Language
    • History
    • Math
    • Science
    • Social Science

    Top subcategories

    • Advanced Math
    • Algebra
    • Basic Math
    • Calculus
    • Geometry
    • Linear Algebra
    • Pre-Algebra
    • Pre-Calculus
    • Statistics And Probability
    • Trigonometry
    • other →

    Top subcategories

    • Astronomy
    • Astrophysics
    • Biology
    • Chemistry
    • Earth Science
    • Environmental Science
    • Health Science
    • Physics
    • other →

    Top subcategories

    • Anthropology
    • Law
    • Political Science
    • Psychology
    • Sociology
    • other →

    Top subcategories

    • Accounting
    • Economics
    • Finance
    • Management
    • other →

    Top subcategories

    • Aerospace Engineering
    • Bioengineering
    • Chemical Engineering
    • Civil Engineering
    • Computer Science
    • Electrical Engineering
    • Industrial Engineering
    • Mechanical Engineering
    • Web Design
    • other →

    Top subcategories

    • Architecture
    • Communications
    • English
    • Gender Studies
    • Music
    • Performing Arts
    • Philosophy
    • Religious Studies
    • Writing
    • other →

    Top subcategories

    • Ancient History
    • European History
    • US History
    • World History
    • other →

    Top subcategories

    • Croatian
    • Czech
    • Finnish
    • Greek
    • Hindi
    • Japanese
    • Korean
    • Persian
    • Swedish
    • Turkish
    • other →
 
Profile Documents Logout
Upload
Roles of dopamine receptor subtypes in
Roles of dopamine receptor subtypes in

... lymphocytes is shown a possibility underlying mechanisms of dopamineinduced cell proliferation. Dopamine receptors have been isolated, characterized and subdivided into two families, D1-like and D2-like receptors, on the basis of their biochemical and pharmacological properties (Vallone et al. 2000) ...
Biological diagnostics, control and treatment of the cholerae.
Biological diagnostics, control and treatment of the cholerae.

... In bacteria, the cell wall forms a rigid structure around the cell. The bacterial cell wall surrounds the cell membrane. Inside the cell wall (or rigid peptidoglycan layer) is the plasma (cytoplasmic) membrane; this is usually closely apposed to the wall layer. Outside of cell wall some bacteria hav ...
(HBV) in a Case of HBV Infection Acquir
(HBV) in a Case of HBV Infection Acquir

Induction of protective immunity to Cryptococcal infection in mice by
Induction of protective immunity to Cryptococcal infection in mice by

... pathogen and the resolution of the fungal infection (7–9). It is well established that cell-mediated immunity (CMI) plays a critical role in anticryptococcal defense, as is evident from the higher prevalence of cryptococcal infections in immunocompromised patients (1). This is recapitulated in anima ...
- Doctor of the Future
- Doctor of the Future

...  Pathogens can also be present and food allergens can create immediate and delayed responses from the ...
SERIES ‘‘RARE INTERSTITIAL LUNG DISEASES’’ Number 2 in this Series
SERIES ‘‘RARE INTERSTITIAL LUNG DISEASES’’ Number 2 in this Series

... EUROPEAN RESPIRATORY JOURNAL ...
Gene Section MME (membrane metallo-endopeptidase) Atlas of Genetics and Cytogenetics
Gene Section MME (membrane metallo-endopeptidase) Atlas of Genetics and Cytogenetics

... Transcriptional regulation: MME is constitutively expressed in some tissues (kidney, adipose tissue, brain) and at some developmental stages in other (Tand B-lymphocytes, neutrophils). Its gene transcription is regulated by at least two alternative regulation regions including type 1 and type 2 prom ...
in MUC1-Transgenic Mice Cells CD8 T Cells by Dendritic/Tumor
in MUC1-Transgenic Mice Cells CD8 T Cells by Dendritic/Tumor

... fused cells (FC/MUC1) were demonstrated to have dual expression of MUC1 and MHC class II or costimulatory molecules by flow cytometry. FC/MUC1 and MC38/MUC1, but not DC, expressed MUC1 (Fig. 1A). FC/MUC1 also expressed MHC class II (Fig. 1A) at a level comparable to that found on DC. To directly vis ...
The role of lysosomal cysteine proteases in crustacean immune
The role of lysosomal cysteine proteases in crustacean immune

Drosophila as a model for the two myeloid blood cell systems in
Drosophila as a model for the two myeloid blood cell systems in

... Figure 1. Ontogeny of blood cell lineages and regulation of hematopoiesis in Drosophila. (A) Self-renewing tissue hemocytes, which emerge and expand during Drosophila embryonic and larval hematopoiesis. Drosophila tissue hemocytes originate as prohemocyte progenitors (blue) in the head mesoderm at a ...
Vaccine Development Using Recombinant DNA Technology
Vaccine Development Using Recombinant DNA Technology

... is injected directly into the animal, usually intramuscularly or intradermally (into the skin). The animal’s cells take up the DNA, and an immune response is induced to the protein expressed from the foreign gene. In addition to genes coding for immunogenic proteins, genetic vaccines also have been ...
Complement
Complement

... (DAF), Complement receptor 1 (CR1), proteinS (vitronectin) ...
Vaccine Development Using Recombinant DNA Technology
Vaccine Development Using Recombinant DNA Technology

... is injected directly into the animal, usually intramuscularly or intradermally (into the skin). The animal’s cells take up the DNA, and an immune response is induced to the protein expressed from the foreign gene. In addition to genes coding for immunogenic proteins, genetic vaccines also have been ...
b - Repositório da Universidade de Lisboa
b - Repositório da Universidade de Lisboa

IRAK4 and TLR3 sequence variants may alter breast cancer risk
IRAK4 and TLR3 sequence variants may alter breast cancer risk

... This missense mutation introduces a potential phosphorylation site in the extreme carboxy terminus (XCT) of the IRAK4 kinase domain. Preliminary molecular modeling predicts that this SNP stabilizes two alpha helices within the XCT on the surface of the IRAK4 kinase domain and increases the size of t ...
Vaccine Development Using Recombinant DNA Technology
Vaccine Development Using Recombinant DNA Technology

WAPT - Wits University
WAPT - Wits University

Here - European Macrophage and Dendritic Cell Society
Here - European Macrophage and Dendritic Cell Society

... the category “immunology, microbiology and virology”. All this is meant to emphasize that immunology is very close to our hearts. Needless to say that many of us have had a strong and long-standing interest in macrophages and dendritic cells. This year´s EMDS meeting focusses on the interaction of m ...
Evolutionary insights into the origin of innate and adaptive immune
Evolutionary insights into the origin of innate and adaptive immune

... mutation exhibited by all kinds of microbes are unpredictable, the best option for the host is to find the most flexible ways and means to diversify its defense mechanism. One way to do that is to rapidly and randomly generate and expand the specificity of their adaptive immune capacity. The diversi ...
Antiviral Protection Cell Cross-Presentation, CTL Responses, and
Antiviral Protection Cell Cross-Presentation, CTL Responses, and

... DC, inducing expression of costimulatory molecules and cytokines, which together with MHC-Ag complexes induce cognate T cells to differentiate into Ag-specific CTL and Th cells (8–11). DC recognize pathogen-associated molecular patterns (PAMPs) and many adjuvants using receptors of the innate immune ...
Steroid Hormone Regulation of Cytokine Secretion by Proteolipid
Steroid Hormone Regulation of Cytokine Secretion by Proteolipid

Plasmacytoid Dendritic Cells and the Control of Herpesvirus Infections
Plasmacytoid Dendritic Cells and the Control of Herpesvirus Infections

Adaptive Immune Responses in the Intestinal Mucosa of
Adaptive Immune Responses in the Intestinal Mucosa of

... Ashok Kumar Kumawat (2013): Adaptive Immune Responses in the Intestinal Mucosa of Microscopic Colitis Patients, Örebro Studies in Medicine, 84, 83pp. Microscopic colitis (MC) is a chronic diarrhoeal disease of unknown aetiology, comprising collagenous colitis (CC) and lymphocytic colitis (LC). The n ...
Reprint - Immune Tolerance Network
Reprint - Immune Tolerance Network

... the engagement of their T-cell receptors locally at the site of antigen deposition. In a mouse model of autoimmune diabetes and autoimmune pancreatitis, we have observed complete protection against islet destruction using islet antigen-specific Tregs, whereas autoimmune attack of the surrounding exo ...
clever-1 as an immune suppressive molecule
clever-1 as an immune suppressive molecule

< 1 ... 42 43 44 45 46 47 48 49 50 ... 514 >

Molecular mimicry

Molecular mimicry is defined as the theoretical possibility that sequence similarities between foreign and self-peptides are sufficient to result in the cross-activation of autoreactive T or B cells by pathogen-derived peptides. Despite the promiscuity of several peptide sequences which can be both foreign and self in nature, a single antibody or TCR (T cell receptor) can be activated by even a few crucial residues which stresses the importance of structural homology in the theory of molecular mimicry. Upon the activation of B or T cells, it is believed that these ""peptide mimic"" specific T or B cells can cross-react with self-epitopes, thus leading to tissue pathology (autoimmunity). Molecular mimicry is a phenomenon that has been just recently discovered as one of several ways in which autoimmunity can be evoked. A molecular mimicking event is, however, more than an epiphenomenon despite its low statistical probability of occurring and these events have serious implications in the onset of many human autoimmune disorders. In the past decade the study of autoimmunity, the failure to recognize self antigens as ""self,"" has grown immensely. Autoimmunity is a result of a loss of immunological tolerance, the ability for an individual to discriminate between self and non-self. Growth in the field of autoimmunity has resulted in more and more frequent diagnosis of autoimmune diseases. Consequently, recent data show that autoimmune diseases affect approximately 1 in 31 people within the general population. Growth has also led to a greater characterization of what autoimmunity is and how it can be studied and treated. With an increased amount of research, there has been tremendous growth in the study of the several different ways in which autoimmunity can occur, one of which is molecular mimicry. The mechanism by which pathogens have evolved, or obtained by chance, similar amino acid sequences or the homologous three-dimensional crystal structure of immunodominant epitopes remains a mystery.
  • studyres.com © 2025
  • DMCA
  • Privacy
  • Terms
  • Report