• Study Resource
  • Explore
    • Arts & Humanities
    • Business
    • Engineering & Technology
    • Foreign Language
    • History
    • Math
    • Science
    • Social Science

    Top subcategories

    • Advanced Math
    • Algebra
    • Basic Math
    • Calculus
    • Geometry
    • Linear Algebra
    • Pre-Algebra
    • Pre-Calculus
    • Statistics And Probability
    • Trigonometry
    • other →

    Top subcategories

    • Astronomy
    • Astrophysics
    • Biology
    • Chemistry
    • Earth Science
    • Environmental Science
    • Health Science
    • Physics
    • other →

    Top subcategories

    • Anthropology
    • Law
    • Political Science
    • Psychology
    • Sociology
    • other →

    Top subcategories

    • Accounting
    • Economics
    • Finance
    • Management
    • other →

    Top subcategories

    • Aerospace Engineering
    • Bioengineering
    • Chemical Engineering
    • Civil Engineering
    • Computer Science
    • Electrical Engineering
    • Industrial Engineering
    • Mechanical Engineering
    • Web Design
    • other →

    Top subcategories

    • Architecture
    • Communications
    • English
    • Gender Studies
    • Music
    • Performing Arts
    • Philosophy
    • Religious Studies
    • Writing
    • other →

    Top subcategories

    • Ancient History
    • European History
    • US History
    • World History
    • other →

    Top subcategories

    • Croatian
    • Czech
    • Finnish
    • Greek
    • Hindi
    • Japanese
    • Korean
    • Persian
    • Swedish
    • Turkish
    • other →
 
Profile Documents Logout
Upload
Embrionary way to create a fatty liver in portal hypertension
Embrionary way to create a fatty liver in portal hypertension

... their anatomical position, the venous blood from there is drained directly into the liver through the portal vein[52]. We speculate that the induction of intraabdominal fat deposits around the portal venous system could represent ontogenic reminiscences, associated with yolk sac, or phylogenetic rem ...
The roles of platelets in inflammation, immunity, wound healing and
The roles of platelets in inflammation, immunity, wound healing and

... Abstract: The roles of platelets as essential effector cells in hemostasis have been known for over a century. Platelets also have many other functions, which are facilitated by their complex morphological structures and their ability to synthesize and store a variety of biochemical substances. Thes ...
Full-Text PDF
Full-Text PDF

Purpose
Purpose

as a PDF
as a PDF

... From the foregoing, it is obvious that the cultured species of the Bacteria and Archaea (172) represent only a minor fraction of the existing diversity. Today, about 5,000 species have been described (23), with the Approved List of Bacterial Names currently containing less than 3,500 entries. Since ...
Immune Response During Transition – Lessard, et. al.
Immune Response During Transition – Lessard, et. al.

... reduced, and different types of antibody response to antigenic stimulations were developed compared with mice fed an n-6 enriched diet (Albers et al., 2002). Mechanisms involved in the regulation of immune response are not yet completely understood, but there is evidence that PUFA influence cellular ...
24. Lymphatic System
24. Lymphatic System

... nutrients are absorbed directly into the bloodstream, some larger materials, such as lipids and lipid-soluble vitamins, are unable to enter the bloodstream directly from the gastrointestinal (GI) tract. These materials are transported through tiny lymph vessels called lacteals, which drain into larg ...
Localization of H.pylori within the Vacuole of CandidaYeast by Di
Localization of H.pylori within the Vacuole of CandidaYeast by Di

Immunoprophylaxis
Immunoprophylaxis

... mAb against cytokines:TNF mAb-directed therapy mAb coupled to isotopes, drugs, toxins ...
Table 1: Membrane damaging toxins
Table 1: Membrane damaging toxins

... single serotype of Clostridium botulinum, and given the addition of a letter A-G [chronology of discovery described in Erbguth et al, 2008]. All have a similar, conserved amino acid sequence. Only four of these serotypes are found to be able to cause botulism in humans, namely A, B, E and F. Botulin ...
Immunological Studies in Malignant Melanoma: Importance of TNF and the Thioredoxin System
Immunological Studies in Malignant Melanoma: Importance of TNF and the Thioredoxin System

... Diagnosis of and prognostic factors in MM The typical melanoma lesion is relatively easy to identify, even macroscopically, as an irregularly growing, pigmented lesion that after a long time (even decades) of inactivity can debut with symptoms such as accelerated growth, itching and bleeding. Pathol ...
Flow Cytometric Analysis of Crayfish Hemocytes.
Flow Cytometric Analysis of Crayfish Hemocytes.

Antimicrobial Drug Discovery
Antimicrobial Drug Discovery

... environments. These microbes have many important planetary roles, but for us humans a major problem is their ability to colonize our tissues and cause disease. The same techniques of molecular and cellular microbiology have been applied to the problems of human and animal infection during the past t ...
Monoclonal Antibodies for Therapeutic Use: Specific Characteristics
Monoclonal Antibodies for Therapeutic Use: Specific Characteristics

... The use of animal models during the development of MoAb is difficult due to the between-species differences of the “partners” of the MoAb, i.e. target antigen and immune effectors (including FcγR receptors).[19] MoAb do not usually recognise target antigens in the mouse. These models therefore requi ...
Micro Chapter 12 [4-20
Micro Chapter 12 [4-20

... o Despite the ways to fight opsonization, our antibodies still usually win out and opsonize M proteins o The problem is that there are so many different types of M proteins, that we often don’t have antibodies built up to them The hyaluronic acid capsule is another antiphagocyte structure on the str ...
Chromatin as a target antigen in human and murine lupus nephritis
Chromatin as a target antigen in human and murine lupus nephritis

Protective effect of the maternally derived porcine circovirus type 2
Protective effect of the maternally derived porcine circovirus type 2

View/Open - Minerva Access
View/Open - Minerva Access

... to contain distinctive differences in the LPS profile when compared to that of their parent OM. LPS is a major structural element of the bacterial OM and has three constituent components: lipid A, core oligosaccharide and O antigen polysaccharide. Distinctive LPS profiles of OMV and OM preparations ...
Mucosal Vaccines: Where Do We Stand?
Mucosal Vaccines: Where Do We Stand?

F1-ATPase`
F1-ATPase`

... of plant mitochondria is quite different. In comparison to the amount of information that has been accumulated in animal systems, very little is actually known about the characteristics of plant mitochondrial F1-ATPase. This is in large part due to the difficulties involved in isolating large quanti ...
Allergic conjunctivitis: a comprehensive review of the literature Open Access
Allergic conjunctivitis: a comprehensive review of the literature Open Access

... Contact allergy, or allergic contact dermatitis, is not an IgEmediated allergy, and can be considered in a different category than the before mentioned allergic conditions [24]. It is a type-IV delayed hypersensitivity response, that occurs through interaction of antigens with Th1 and Th2 cell subse ...
The Role of Interleukin-6 in the Febrile Response Namik Hamzic
The Role of Interleukin-6 in the Febrile Response Namik Hamzic

... can subsequently mount a stronger response if the same pathogen is detected again, hence providing us with acquired immunity against the specific pathogen. The recognition of the pathogens by the innate immune system relies on the cells equipped with pattern recognition receptors (PRRs) that can be ...
INTRODUCTION Corticotrophin-releasing hormone (CRH) is a 41
INTRODUCTION Corticotrophin-releasing hormone (CRH) is a 41

... responses to incubation with 56 mM KCl seen to date (11). One of the advantages of this system is the fact that minimal trauma to the tissue can be ensured through the taking of extreme care in brain removal and dissection procedures, as well as thanks to the CSF-like fluid surrounding the preparati ...
Allergic conjunctivitis: a comprehensive review of the literature
Allergic conjunctivitis: a comprehensive review of the literature

... Contact allergy, or allergic contact dermatitis, is not an IgEmediated allergy, and can be considered in a different category than the before mentioned allergic conditions [24]. It is a type-IV delayed hypersensitivity response, that occurs through interaction of antigens with Th1 and Th2 cell subse ...
International Society for Biological Therapy of Cancer 24th Annual
International Society for Biological Therapy of Cancer 24th Annual

... only must gene transfer introduce a desired immunoreceptor, but T cells should be manipulated ex vivo to maintain their replicative potential and effector functions. To fulfill the promise of T cells as biologic therapies, iterative changes are needed to genetically modify, then remodify T cells as we ...
< 1 ... 8 9 10 11 12 13 14 15 16 ... 514 >

Molecular mimicry

Molecular mimicry is defined as the theoretical possibility that sequence similarities between foreign and self-peptides are sufficient to result in the cross-activation of autoreactive T or B cells by pathogen-derived peptides. Despite the promiscuity of several peptide sequences which can be both foreign and self in nature, a single antibody or TCR (T cell receptor) can be activated by even a few crucial residues which stresses the importance of structural homology in the theory of molecular mimicry. Upon the activation of B or T cells, it is believed that these ""peptide mimic"" specific T or B cells can cross-react with self-epitopes, thus leading to tissue pathology (autoimmunity). Molecular mimicry is a phenomenon that has been just recently discovered as one of several ways in which autoimmunity can be evoked. A molecular mimicking event is, however, more than an epiphenomenon despite its low statistical probability of occurring and these events have serious implications in the onset of many human autoimmune disorders. In the past decade the study of autoimmunity, the failure to recognize self antigens as ""self,"" has grown immensely. Autoimmunity is a result of a loss of immunological tolerance, the ability for an individual to discriminate between self and non-self. Growth in the field of autoimmunity has resulted in more and more frequent diagnosis of autoimmune diseases. Consequently, recent data show that autoimmune diseases affect approximately 1 in 31 people within the general population. Growth has also led to a greater characterization of what autoimmunity is and how it can be studied and treated. With an increased amount of research, there has been tremendous growth in the study of the several different ways in which autoimmunity can occur, one of which is molecular mimicry. The mechanism by which pathogens have evolved, or obtained by chance, similar amino acid sequences or the homologous three-dimensional crystal structure of immunodominant epitopes remains a mystery.
  • studyres.com © 2025
  • DMCA
  • Privacy
  • Terms
  • Report