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AUTOIMMUNE ENDOCRINE DISEASES
AUTOIMMUNE ENDOCRINE DISEASES

... that allowed beta cell reactive T cells to emigrate from the thymus during development and that these cells were activated by the viral infection- this one may prove to be true but suffice it to say, no one knows the cause of Type 1 diabetes yet! ...
Auto-immune diseases – 19/03/03
Auto-immune diseases – 19/03/03

... Control against reactivity to self antigens (see above under Tolerance) Aeitology of autoimmune disease – Multifactorial (Abbas 179) So what is the cause of autoimmune disease? Basically, the cause is many. 1) Some proteins/cells and other components in the body are sequestered. This means, under n ...
AJS_Paper3_Autoimmunity
AJS_Paper3_Autoimmunity

... lifelong consequences. By an unknown mechanism, the immune system kills the insulinproducing beta cells in the pancreas. Insulin is the hormone that enables the body to absorb glucose from the bloodstream. People who suffer from T1D must closely monitor their blood-glucose levels and ensure they are ...
Ch06-Diseases of Immunity
Ch06-Diseases of Immunity

... • CYTOKINES are PROTEINS produced by MANY cells, but usually LYMPHOCYTES and MACROPHAGES, numerous roles in acute and chronic inflammation, AND immunity ...
MCB_5255_files/Redox stress intro slides mcb 5255
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... – Discrimination of self vs non-self • Central tolerance develops in thymus and bone marrow – (negative selection to eliminate cells reactive with antigens » Present soon after cell expresses antigen receptor » Present at high concentration over long periods of time ...
Intravenous Immunoglobulin in Autoimmune Neuromuscular
Intravenous Immunoglobulin in Autoimmune Neuromuscular

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the scientific sessions
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... ...
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Who Gets Lupus?
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The Immune System Second Edition
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Immune Tolerance

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Immune system08
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... HIV (human immunodeficiency virus) infection will lead to immune system collapse • HIV usually invades helper T cell, which begin to produce HIV soon after infection. • Helper T cell die, the – immune system gradually weakens – becomes overwhelmed by pathogens that would normally detect and destroy. ...
Introduction to Biology II
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... becomes hyperactive and attacks normal tissue. This attack results in inflammation and brings about symptoms. This is a "Nonorgan-specific" type of autoimmune disease. Multiple sclerosis is a disorder of the central nervous system (brain and spinal cord) characterised by decreased nerve function due ...
autoimmunity
autoimmunity

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Ch6-Immune Desease
Ch6-Immune Desease

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autoimmune diseases
autoimmune diseases

... - internal (HLA association, polymorphism of cytokine genes, defect in genes regulating apoptosis, polymorphism in genes for TCR and H immunoglobulin chains, association with immunodeficiency, hormonal factors) - external (infection, stress by activation of neuroendocrinal axis and hormonal dysbalan ...
autoimmune diseases
autoimmune diseases

... - internal (HLA association, polymorphism of cytokine genes, defect in genes regulating apoptosis, polymorphism in genes for TCR and H immunoglobulin chains, association with immunodeficiency, hormonal factors) - external (infection, stress by activation of neuroendocrinal axis and hormonal dysbalan ...
Qi Mail - Needles and Tea
Qi Mail - Needles and Tea

... Autoimmune diseases are a group of disorders in which the immune system attacks the body and destroys or alters tissues. There are more than eighty serious chronic illnesses in this category including rheumatoid arthritis, type 1 diabetes, lupus, thyroid disease, inflammatory bowel disease, Addison' ...
Document
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... diseases • Chronic diseases in which inflammation is a prominent component and the immune system reacts excessively against one or more tissues • Immune-mediated inflammatory diseases develop because the normal controls on immune responses fail; typically due to autoimmunity but may be excessive rea ...
Autoimmune Disease
Autoimmune Disease

... Autoimmune Disease immune system fails to recognize some of the body’s tissues as “self” - Like a “case of mistaken identity” ...
Autoimmunity - Lehigh University
Autoimmunity - Lehigh University

... • NZB spontaneously develops autoimmune hemolytic anemia between 2-4 months of age – At this point various antibodies can be detected. These antibodies include antibodies to erthyocytes, nuclear proteins, DNA and T lymphocytes – F1 hybrids develop glomerulonephritis from immunecomplex deposits in th ...
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Autoimmunity

Autoimmunity is the system of immune responses of an organism against its own cells and tissues. Any disease that results from such an aberrant immune response is termed an autoimmune disease. Prominent examples include Celiac disease, diabetes mellitus type 1, Sarcoidosis, systemic lupus erythematosus (SLE), Sjögren's syndrome, Churg-Strauss Syndrome, Hashimoto's thyroiditis, Graves' disease, idiopathic thrombocytopenic purpura, Addison's Disease, rheumatoid arthritis (RA), Polymyositis (PM), and Dermatomyositis (DM). Autoimmune diseases are very often treated with steroids.The misconception that an individual's immune system is totally incapable of recognizing self antigens is not new. Paul Ehrlich, at the beginning of the twentieth century, proposed the concept of horror autotoxicus, wherein a ""normal"" body does not mount an immune response against its own tissues. Thus, any autoimmune response was perceived to be abnormal and postulated to be connected with human disease. Now, it is accepted that autoimmune responses are an integral part of vertebrate immune systems (sometimes termed ""natural autoimmunity""), normally prevented from causing disease by the phenomenon of immunological tolerance to self-antigens. Autoimmunity should not be confused with alloimmunity.
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