• Study Resource
  • Explore
    • Arts & Humanities
    • Business
    • Engineering & Technology
    • Foreign Language
    • History
    • Math
    • Science
    • Social Science

    Top subcategories

    • Advanced Math
    • Algebra
    • Basic Math
    • Calculus
    • Geometry
    • Linear Algebra
    • Pre-Algebra
    • Pre-Calculus
    • Statistics And Probability
    • Trigonometry
    • other →

    Top subcategories

    • Astronomy
    • Astrophysics
    • Biology
    • Chemistry
    • Earth Science
    • Environmental Science
    • Health Science
    • Physics
    • other →

    Top subcategories

    • Anthropology
    • Law
    • Political Science
    • Psychology
    • Sociology
    • other →

    Top subcategories

    • Accounting
    • Economics
    • Finance
    • Management
    • other →

    Top subcategories

    • Aerospace Engineering
    • Bioengineering
    • Chemical Engineering
    • Civil Engineering
    • Computer Science
    • Electrical Engineering
    • Industrial Engineering
    • Mechanical Engineering
    • Web Design
    • other →

    Top subcategories

    • Architecture
    • Communications
    • English
    • Gender Studies
    • Music
    • Performing Arts
    • Philosophy
    • Religious Studies
    • Writing
    • other →

    Top subcategories

    • Ancient History
    • European History
    • US History
    • World History
    • other →

    Top subcategories

    • Croatian
    • Czech
    • Finnish
    • Greek
    • Hindi
    • Japanese
    • Korean
    • Persian
    • Swedish
    • Turkish
    • other →
 
Profile Documents Logout
Upload
Notes: Chapter 39 Reading Guide (page 1022
Notes: Chapter 39 Reading Guide (page 1022

... • Macrophages recognize and engulf a foreign invader which activates helper T-cells • Helper T-cells then activate B-cells • B-cells mature into plasma cells and make antibodies against the specific pathogen • Memory B-cells and T-cells hang around in case the pathogen shows up again later – Quick r ...
Ppoint - Dr. Stuart White
Ppoint - Dr. Stuart White

... Lack of methylation, inability to accomplish Phase I and Phase II detoxification results in failure of the methylation processes and subsequent accumulation of nuclear proteins in the blood compelling an immune response The primary factors that contribute to autoimmunity are genetic predisposition ...
Autoimmune Diseases and Therapeutic Approaches Open Access
Autoimmune Diseases and Therapeutic Approaches Open Access

... literature. Schistosomiasis might induce autoimmune activity by several mechanisms: molecular mimicry, production of pathogenic autoantibodies, polyclonal activation of B cells, ...
Chap 18 AIDS and Immune Disorders
Chap 18 AIDS and Immune Disorders

... • Occur more often in the elderly • Are more common in women than in men • May result when an individual begins to make autoantibodies or cytotoxic T cells against normal body components ...
Other T cells, known as cytotoxic, killer, or CD8+ T cells, attack and
Other T cells, known as cytotoxic, killer, or CD8+ T cells, attack and

... In the study of autoimmune disease, the most significant unanswered question is what possesses T cells to turn against their host. It is generally accepted that a combination of genetic susceptibility and environmental stimuli sets the stage for autoimmune disease. The different alleles of HLA, vari ...
The Selective p110 Inhibitor IPI-3063 Potently Suppresses B Cell
The Selective p110 Inhibitor IPI-3063 Potently Suppresses B Cell

... The phosphoinositide-3-kinase (PI3K) signaling pathway is a crucial pathway that is involved in many cellular processes such as differentiation, proliferation and cell survival. The p110δ catalytic isoform of PI3K is critical for these cellular processes in B lymphocytes. Elevated PI3K signaling, ho ...
Immunology Male et al., 8 th Ed. 2013.
Immunology Male et al., 8 th Ed. 2013.

... relationship to other sciences and biological systems of mammals. This course will concentrate on function-structure relationship of the immune system and its components such as the lymphoid tissue and cells, the development and function of the immune system, as well as the clinical science of the i ...
Lesson 64. Auto Immunity and auto immune diseases
Lesson 64. Auto Immunity and auto immune diseases

... by various mechanisms. Failure in immune recognition of self and injury of self tissues (autoimmunity) results from a loss of self tolerance. Let us discuss the mechanisms of self tolerance and how it is broken down to result in autoimmunity. 64.4.1 Mechanisms of self tolerance One mechanism is that ...
Maladies auto-immunes
Maladies auto-immunes

... – Anomalies des T helper : production auto‐Ac ...
Immunity Questions
Immunity Questions

... 2. How do the words innate and acquired relate to when these types of immunity develop in a human body? 3. Describe the function of the following cells and chemicals of the innate immune system: macrophages, natural killer (NK) cells, mast cells, histamine, interferons, complement system, and chemok ...
Malfunctions and Disorders
Malfunctions and Disorders

... may be viral or bacterial ** (the meninges are tissue that surrounds the vertebrae and brain). ...
Ocular immunopathology
Ocular immunopathology

... Hen egg lysozyme peptides ...
Course Code Course Title ECTS Credits PHAR
Course Code Course Title ECTS Credits PHAR

... Important mechanisms of the immune system are involved in autoimmune disease, chronic inflammation, transplantation, allergy and vaccination. In addition, many drugs act either as immunosuppressants or immunomodulators, it is therefore crucial for the Pharmacy students to have a general but good kno ...
Immuno Revision Notes
Immuno Revision Notes

...  Lymphocyte counts + serum immunoglobulins  Flow cytometry  Measure antibody response to known pathogens (tetanus, H.influenza, Strep. Pneumoniae) Management  Ig replacement – i.v. every 3‐4 weeks  Immunisation is not effective (except IgA) T cell deficiencies General PresentaIon  Infections o ...
Immune Deficiency AIDS
Immune Deficiency AIDS

... • Occur more often in the elderly • Are more common in women than in men • May result when an individual begins to make autoantibodies or cytotoxic T cells against normal body components ...
Autoimmune Diseases - The Dartmouth Undergraduate Journal of
Autoimmune Diseases - The Dartmouth Undergraduate Journal of

... of antibodies and mount larger inflammatory responses than men when their immune systems are triggered, possibly increasing the risk of autoimmunity (3, 13). Autoimmune diseases tend to fluctuate in accordance with hormonal changes, such as during pregnancy, menstrual cycle, menopause, aging and usa ...
Health Notes KD16
Health Notes KD16

...  a) Autoimmune Disease: your own immune system attacks your body  Ex: Allergies, Type I Diabetes, Lupus, Rheumatoid arthritis  b) Cardiovascular Disease  Ex: heart attack, stroke, high blood pressure ...
Ankylosing Spondylitis or Marie-Strumpell Disease
Ankylosing Spondylitis or Marie-Strumpell Disease

... arthritis of the extremities may soon follow. Although the exact cause of the disease remains unknown, an autoimmune process is strongly suspected. This would make it fall into the category of diseases such as: lupus, rheumatoid arthritis, and scleroderma. X-ray or an MRI of the sacroiliac joint usu ...
Specific Immunity Immuno-competency competency Types of
Specific Immunity Immuno-competency competency Types of

... symptoms, but sensitizes the individual. Later encounter can set up an extreme reaction of the immune system. Involves: T cells, B cells, mast cells (detector cells) and basophils. Massive release of histamines by mast cells. Asthma type symptoms occur. > Epinephrine is the drug of choice to reverse ...
Mechanisms of Autoimmunity
Mechanisms of Autoimmunity

... with the autoantigens exist in normal animals. Therefore, it is believed that the existence of autoantibodies or autoreactive T cells is not enough to elicit autoimmune diseases. In addition, it has been recently speculated that auto-reactivity at a low level is physiological and necessary for a nor ...
Autoimmune Diseases
Autoimmune Diseases

... HLA Association of Autoimmune Diseases Depletion of Autoreactive T Cells in the Thymus How does autoantibody cause diseases • Direct binding to target cells thyrotoxicosis Myasthenia gravis Goodpasture’s syndrome ...
Autoimmune - Treg 2012
Autoimmune - Treg 2012

... Defective central tolerance: Autoimmune PolyEndocrinopathy Candidiasis-Ectodermal Dystrophy (APECED), AIRE deficiency Finnish population, Sardinians, Iranian Jews ...
Chapter One Concept Checks
Chapter One Concept Checks

... 3. Highly specific molecules that act as antibodies. They combine with antigens to neutralize them. ____________ 4. Lymphocytes that operate within the humoral part of the system and circulate in the blood and bodily fluids. ____________ 5. These are created so that when a specific antigen is encoun ...
LOYOLA COLLEGE (AUTONOMOUS), CHENNAI – 600 034
LOYOLA COLLEGE (AUTONOMOUS), CHENNAI – 600 034

... 3. Delayed type of hypersensitivity is____________hypersensitivity a) Type1 b) Type2 c) Type3 d) Type 4 4. The most devastating Pandemic disease in human was caused by a) Variola vera b) Yersinia pestis c) H1N1 d) HIV 5. Individual cells can be sorted by a) Immunosensors b) ELISPOT c) Flow cytometry ...
Immune
Immune

... • Caused by the Human Immunodeficiency Virus (HIV) • Capable of becoming multi-drug resistant • AIDS is the final stage of the HIV infection • Average incubation period for AIDS development is 10 years from point of infection • Characterized by “opportunistic infections” • There is no cure!! ...
< 1 ... 60 61 62 63 64 65 66 67 68 ... 72 >

Autoimmunity

Autoimmunity is the system of immune responses of an organism against its own cells and tissues. Any disease that results from such an aberrant immune response is termed an autoimmune disease. Prominent examples include Celiac disease, diabetes mellitus type 1, Sarcoidosis, systemic lupus erythematosus (SLE), Sjögren's syndrome, Churg-Strauss Syndrome, Hashimoto's thyroiditis, Graves' disease, idiopathic thrombocytopenic purpura, Addison's Disease, rheumatoid arthritis (RA), Polymyositis (PM), and Dermatomyositis (DM). Autoimmune diseases are very often treated with steroids.The misconception that an individual's immune system is totally incapable of recognizing self antigens is not new. Paul Ehrlich, at the beginning of the twentieth century, proposed the concept of horror autotoxicus, wherein a ""normal"" body does not mount an immune response against its own tissues. Thus, any autoimmune response was perceived to be abnormal and postulated to be connected with human disease. Now, it is accepted that autoimmune responses are an integral part of vertebrate immune systems (sometimes termed ""natural autoimmunity""), normally prevented from causing disease by the phenomenon of immunological tolerance to self-antigens. Autoimmunity should not be confused with alloimmunity.
  • studyres.com © 2025
  • DMCA
  • Privacy
  • Terms
  • Report