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report from the Study Group f
report from the Study Group f

... to be the best to describe the phase during which abnormalities in various body compartments can be found preceding the clinical expression of the disease. Although the synovium is the principal site of pathology in the established phase of disease, it may not be the site where the disease is initia ...
Rheumatoid arthritis is an autoimmune disease in which the target
Rheumatoid arthritis is an autoimmune disease in which the target

... cells. This is a complex and multi-layered strategy that is almost always completely effective. However, if this process is circumvented or breaks down, the results are self-reactive immune response cells. This state of immune reactivity and the inflammatory damage causes an autoimmune disease [3]. ...
Hormones Cytokines neuropeptides GrowtH faCtors APPENDIX
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... mainly colocalized with macrophages. With the goal of determining if these powerful immunomodulatory molecules contribute to the pathology seen in twitcher mice, double knockout twitcher mice that are deWcient in IL-6 protein or the TNF- receptor-1 (TNFR1) were generated [93, 94]. Surprisingly, twi ...
Intervention (Mild and Moderate Reactions)
Intervention (Mild and Moderate Reactions)

... 3. An Immune response consists of two phases. In the first phase, antigen activates specific lymphocytes that recognize it; in the effector phase, these lymphocytes coordinate an immune response that eliminates that source of the antigens. 4. Specificity and memory are two essential features of adap ...
C7. Time schedule of the research plan solution
C7. Time schedule of the research plan solution

... Scientific work represents one of the central points of the Faculty activities. It contributes to its high standards and its status on an international level. A few internationally respected groups work at the 2nd Medical Faculty - Charles University, both in the field of basic and applied clinical ...
Systemic Lupus Erythematosus - UC Irvine`s Department of Medicine
Systemic Lupus Erythematosus - UC Irvine`s Department of Medicine

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UNIT 6 – READING AND LEARNING GUIDE TOPICS TO KNOW
UNIT 6 – READING AND LEARNING GUIDE TOPICS TO KNOW

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a PDF of this article

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... frank pus yielded only a few colonies of skin and environmental organisms. All was shadows and fog, and the reputations of the microbiology units of many hospitals plummeted from the high levels they had attained earlier.” Biofilms have material properties similar to those of a viscous fluid and mic ...
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... hospital. We had observed 96 children from one month to three years with Shigellosis. Patients were divided into two groups according to the course of the disease. The first group included 65 patients with smooth-like course (SC) of the disease, second group - 31 patients with wavy-like course (WC) ...
The Immune System
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... bone marrow and complete their development there or in the spleen. B cells make antibodies. – T cells are cells that are made in the bone marrow but complete their development only after traveling to the thymus. T cells also participate in many immune reactions. ...
Chapter 2 Antigen
Chapter 2 Antigen

... • Compared to a normal antigen-induced Tcell response where 0.001-0.0001% of the body’s T-cells are activated, SAgs are capable of activating up to 20% of the body’s T-cells. This causes a massive immune response that is not specific to any particular epitope on the SAg. ...
Template to create a scientific poster
Template to create a scientific poster

... within a given mouse strain or human individual” (emphasis added).17 • Indeed gene allelism is rather useful for self/non-self determination amongst individuals of a species. ...
Chapter 2 Antigen
Chapter 2 Antigen

... • Compared to a normal antigen-induced Tcell response where 0.001-0.0001% of the body’s T-cells are activated, SAgs are capable of activating up to 20% of the body’s T-cells. This causes a massive immune response that is not specific to any particular epitope on the SAg. ...
Full Text in English  - Health Science Journals: Indonesia
Full Text in English - Health Science Journals: Indonesia

... Introduction In some pathogenesis of diseases, environmental factors, genetics, as well as host response form complex interplay giving rise to the clinical signs and symptoms. Some immunological disorders such as rheumatoid arthritis, systemic lupus erythematosus, irritable bowel syndrome and coelia ...
lymphmedterm - Weatherford High School
lymphmedterm - Weatherford High School

... •An acute infectious disease caused by the Epstein-Barr virus •Swollen lymph nodes are a common symptom ...
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... invasion of pathogens. Meanwhile, microbes have evolved to survive in the host. 2. Innate and adaptive immune responses (for vertebrates) => An integrated system of host defense => Cells & molecules function cooperatively Antigen-presenting cells => Lymphocytes => Effector cells ...
< 1 ... 13 14 15 16 17 18 19 20 21 ... 72 >

Autoimmunity

Autoimmunity is the system of immune responses of an organism against its own cells and tissues. Any disease that results from such an aberrant immune response is termed an autoimmune disease. Prominent examples include Celiac disease, diabetes mellitus type 1, Sarcoidosis, systemic lupus erythematosus (SLE), Sjögren's syndrome, Churg-Strauss Syndrome, Hashimoto's thyroiditis, Graves' disease, idiopathic thrombocytopenic purpura, Addison's Disease, rheumatoid arthritis (RA), Polymyositis (PM), and Dermatomyositis (DM). Autoimmune diseases are very often treated with steroids.The misconception that an individual's immune system is totally incapable of recognizing self antigens is not new. Paul Ehrlich, at the beginning of the twentieth century, proposed the concept of horror autotoxicus, wherein a ""normal"" body does not mount an immune response against its own tissues. Thus, any autoimmune response was perceived to be abnormal and postulated to be connected with human disease. Now, it is accepted that autoimmune responses are an integral part of vertebrate immune systems (sometimes termed ""natural autoimmunity""), normally prevented from causing disease by the phenomenon of immunological tolerance to self-antigens. Autoimmunity should not be confused with alloimmunity.
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