A Complex Suite of Forces Drives Gene Traffic from Drosophila X
... Richard P. Meisel,* Mira V. Han,à and Matthew W. Hahnৠ*Department of Biology and Graduate Program in Genetics, The Pennsylvania State University; Department of Molecular Biology and Evolution, Cornell University; àSchool of Informatics, Indiana University; and §Department of Biology, Indiana Uni ...
... Richard P. Meisel,* Mira V. Han,à and Matthew W. Hahnৠ*Department of Biology and Graduate Program in Genetics, The Pennsylvania State University; Department of Molecular Biology and Evolution, Cornell University; àSchool of Informatics, Indiana University; and §Department of Biology, Indiana Uni ...
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... Sequence analysis and genome building Molecular Structure prediction Evolution, phylogeny and linkage Automated data collection and analysis Simulations and modelling Biological databases and resources ...
... Sequence analysis and genome building Molecular Structure prediction Evolution, phylogeny and linkage Automated data collection and analysis Simulations and modelling Biological databases and resources ...
Identification of One BOCR Mutation and Five NF1 Mutations in Male
... 2015. Two of these patients belonged to the same NF1 family (A1-II:1, III:1), remarkably. Each patient met standard neurofibromatosis I diagnostic criteria created by the National Institute of Health (NIH) [24]. These patients were diagnosed with CPT independently by clinical and radiological signs ...
... 2015. Two of these patients belonged to the same NF1 family (A1-II:1, III:1), remarkably. Each patient met standard neurofibromatosis I diagnostic criteria created by the National Institute of Health (NIH) [24]. These patients were diagnosed with CPT independently by clinical and radiological signs ...
Acoustophoretic sample preparation for PCR in sepsis diagnostics Master’s thesis
... diagnostic system for detecting and identifying bacteria in blood in sepsis. The blood sample is first prepared by separating the substances that inhibit PCR in blood with acoustophoresis, using ultrasound to direct the particles. This study aimed at determining how acoustophoresis and the presence ...
... diagnostic system for detecting and identifying bacteria in blood in sepsis. The blood sample is first prepared by separating the substances that inhibit PCR in blood with acoustophoresis, using ultrasound to direct the particles. This study aimed at determining how acoustophoresis and the presence ...
A Novel CpG Island Set Identifies Tissue-Specific
... sequences [22], both of which are moderately CpG-rich, are hypomethylated in sperm DNA. To avoid contamination of the CGI fraction with sequences that are nonmethylated, specifically in germ cells, whole human blood was used as a source of CGI fragments. Pooled whole blood DNA from three males was fr ...
... sequences [22], both of which are moderately CpG-rich, are hypomethylated in sperm DNA. To avoid contamination of the CGI fraction with sequences that are nonmethylated, specifically in germ cells, whole human blood was used as a source of CGI fragments. Pooled whole blood DNA from three males was fr ...
Conjugative plasmids: vessels of the communal gene pool
... genome analysis of pure culture isolates might have underestimated the true impact of HGT on microbial ecology and evolution. This is supported by a recent report that showed a higher degree of genetic recombination, gene loss and acquisition, transposase movement and purifying selection in the geno ...
... genome analysis of pure culture isolates might have underestimated the true impact of HGT on microbial ecology and evolution. This is supported by a recent report that showed a higher degree of genetic recombination, gene loss and acquisition, transposase movement and purifying selection in the geno ...
Conjugative plasmids: vessels of the communal gene pool
... genome analysis of pure culture isolates might have underestimated the true impact of HGT on microbial ecology and evolution. This is supported by a recent report that showed a higher degree of genetic recombination, gene loss and acquisition, transposase movement and purifying selection in the geno ...
... genome analysis of pure culture isolates might have underestimated the true impact of HGT on microbial ecology and evolution. This is supported by a recent report that showed a higher degree of genetic recombination, gene loss and acquisition, transposase movement and purifying selection in the geno ...
Abundance and distribution of Macrolide
... antibiotics and ammonium, which are, in general, treated by biological processes (Larsson et al., 2007; Ma et al., 2009). However, high antibiotic concentrations and bacterial densities in biological wastewater systems may favor the proliferation of antibiotic resistance genes (ARGs), which could po ...
... antibiotics and ammonium, which are, in general, treated by biological processes (Larsson et al., 2007; Ma et al., 2009). However, high antibiotic concentrations and bacterial densities in biological wastewater systems may favor the proliferation of antibiotic resistance genes (ARGs), which could po ...
Reactome Functional Interaction (FI) Network
... experience: time-consuming and bias; 3. GO annotation and pathway analysis (e.g. Reactome): what biological terms or functional categories are represented in the gene list more often than expected by chance; 4. Network-based analysis. - identify markers not as individual genes but as sub-networks ex ...
... experience: time-consuming and bias; 3. GO annotation and pathway analysis (e.g. Reactome): what biological terms or functional categories are represented in the gene list more often than expected by chance; 4. Network-based analysis. - identify markers not as individual genes but as sub-networks ex ...
Low chromosome number angiosperms
... callus and suspension cultures evidencing polyploidization. Karm et al. (1991) analysed plantlet populations generated in vitro from callus from immature flower heads and karyotype analysis was performed too. Later Ogura et al. (1999) compared the difference of changeability of two pair of homologou ...
... callus and suspension cultures evidencing polyploidization. Karm et al. (1991) analysed plantlet populations generated in vitro from callus from immature flower heads and karyotype analysis was performed too. Later Ogura et al. (1999) compared the difference of changeability of two pair of homologou ...
M2 RNA Pol Ⅰ genes
... transcription initiation. The spacing but not the sequence between the TATA box and the start site is important. Transcription starts with an adenine ~50% of the time. Some eukaryotic genes contain an initiator element instead of a TATA box. The initiator element is located around the transcription ...
... transcription initiation. The spacing but not the sequence between the TATA box and the start site is important. Transcription starts with an adenine ~50% of the time. Some eukaryotic genes contain an initiator element instead of a TATA box. The initiator element is located around the transcription ...
Are Restriction Enzymes Recognition Sites Underrepresented in the
... techniques help to diagnose mutations in certain allelic position without a need of gene sequencing, much more affordable and less time consuming. Restriction site associated DNA mapping (RAD) (14,15), this is useful genotyping tool for associative mapping based on the DNA sequences of restriction s ...
... techniques help to diagnose mutations in certain allelic position without a need of gene sequencing, much more affordable and less time consuming. Restriction site associated DNA mapping (RAD) (14,15), this is useful genotyping tool for associative mapping based on the DNA sequences of restriction s ...
Cophylogeny and disparate rates of evolution in sympatric lineages
... comparisons reveal that both louse complexes show a significant pattern of cophylogeny with their hosts. Comparisons of rates of nucleotide substitution at 4-fold degenerate sites in the COI gene indicate that both groups of lice have significantly higher basal mutation rates than their hosts. The two ...
... comparisons reveal that both louse complexes show a significant pattern of cophylogeny with their hosts. Comparisons of rates of nucleotide substitution at 4-fold degenerate sites in the COI gene indicate that both groups of lice have significantly higher basal mutation rates than their hosts. The two ...
Association of estrogen receptor β gene polymorphisms with bulimic
... been reported and characterized with regard to allele frequency.16–19 Rosenkranz et al16 performed a systematic mutation screening of ERb in probands of different weight extremes and identified five different genetic variants. Only two of these appeared at an allele frequency over 1% for the less co ...
... been reported and characterized with regard to allele frequency.16–19 Rosenkranz et al16 performed a systematic mutation screening of ERb in probands of different weight extremes and identified five different genetic variants. Only two of these appeared at an allele frequency over 1% for the less co ...
... branches where both parents were defined as alcohol dependent by either interview or family history report were not included. Families in which recruitment of all eligible members was completed and blood samples were obtained were reviewed by a committee composed of the principal investigators and o ...
The interaction between the mucosal immune system and the
... and subtraction of background-fluorescence as measured in nonstained suspensions. In order to determine the intra assay variation of measurement of bacterial in vivo IgA coating, replicate analyses of a single faecal sample were included in each series of measurements. Flow cytometry Flow cytometry ...
... and subtraction of background-fluorescence as measured in nonstained suspensions. In order to determine the intra assay variation of measurement of bacterial in vivo IgA coating, replicate analyses of a single faecal sample were included in each series of measurements. Flow cytometry Flow cytometry ...
The photosynthetic apparatus of Prochlorococcus
... is numerically the most abundant, and it can grow deeper in the euphotic zone (Partensky et al., 1999a) presumably because Chl b2 allows it to efficiently harvest the low light intensities and blue wavelengths characteristic of deep water (Moore et al., 1995; Morel et al., 1993). Prochlorococcus iso ...
... is numerically the most abundant, and it can grow deeper in the euphotic zone (Partensky et al., 1999a) presumably because Chl b2 allows it to efficiently harvest the low light intensities and blue wavelengths characteristic of deep water (Moore et al., 1995; Morel et al., 1993). Prochlorococcus iso ...
CYP2B6 NESTED PCR: A GOOD APPROACH FOR PATIENTS ON METHADONE Original Article
... regions are ideal candidates to determine differential drug responses [18]. A number of important SNPs have also been identified within critical gene promoters, which are noncoding regions [19]. The differential drug metabolism caused by genetic variation for the CYP enzymes and in the μ opioid-rece ...
... regions are ideal candidates to determine differential drug responses [18]. A number of important SNPs have also been identified within critical gene promoters, which are noncoding regions [19]. The differential drug metabolism caused by genetic variation for the CYP enzymes and in the μ opioid-rece ...
Full-Text PDF
... to different antibiotic classes and can be used to direct therapy, but are slow and take up to 72 h. In the absence of rapid results, treatment will often use broad-spectrum antibiotics on an empirical basis, which may contribute to increased drug resistance. The emergence of multi-drug-resistant (M ...
... to different antibiotic classes and can be used to direct therapy, but are slow and take up to 72 h. In the absence of rapid results, treatment will often use broad-spectrum antibiotics on an empirical basis, which may contribute to increased drug resistance. The emergence of multi-drug-resistant (M ...
Transcript Isoform Differences Across Human Tissues Are
... Expression (GTEx) project 27 . The dataset comprised 9,795 RNA-seq samples from 54 tissues out of a total of 551 human individuals. Since the dataset did not contain each tissue for each individual, we identified subsets of data that could be analyzed as fully crossed designs (i.e., contained all po ...
... Expression (GTEx) project 27 . The dataset comprised 9,795 RNA-seq samples from 54 tissues out of a total of 551 human individuals. Since the dataset did not contain each tissue for each individual, we identified subsets of data that could be analyzed as fully crossed designs (i.e., contained all po ...
PDF sample
... times. Other than these scarce remains, we have little information about early life on earth. The marine sediments and continental rocks where bacteria may have been deposited have been flattened and heated over time, or recrystalize completely, so that few rocks (and fossils) of this age have rema ...
... times. Other than these scarce remains, we have little information about early life on earth. The marine sediments and continental rocks where bacteria may have been deposited have been flattened and heated over time, or recrystalize completely, so that few rocks (and fossils) of this age have rema ...
Potential virulence and antimicrobial susceptibility of
... comprises 14 species, although its taxonomy remains confusing [2]. Aeromonas popo¤i is one of the most recently described species, and only a few strains have been recovered up to now [3,4]. In an extensive study carried out in our laboratory, some strains showed an atypical biochemical behavior [5] ...
... comprises 14 species, although its taxonomy remains confusing [2]. Aeromonas popo¤i is one of the most recently described species, and only a few strains have been recovered up to now [3,4]. In an extensive study carried out in our laboratory, some strains showed an atypical biochemical behavior [5] ...
Origins and Early Evolution of the Mevalonate
... www.ncbi.nlm.nih.gov/sutils/genom_table .cgi). In eukaryotes, all searches were done against the nonredundant eukaryote-annotated GenBank database. Sequences found by these searches in the three domains of life were aligned with Muscle 3.6 (Edgar 2004), and alignments were edited and manually refine ...
... www.ncbi.nlm.nih.gov/sutils/genom_table .cgi). In eukaryotes, all searches were done against the nonredundant eukaryote-annotated GenBank database. Sequences found by these searches in the three domains of life were aligned with Muscle 3.6 (Edgar 2004), and alignments were edited and manually refine ...
Document
... As experts in human genetic testing, with more than 25 years of experience, we have developed NextGeneDx®, a new NGS-based technology designed to obtain the complete and specific DNA sequence of a simultaneous number of genes involved in inherited diseases. ...
... As experts in human genetic testing, with more than 25 years of experience, we have developed NextGeneDx®, a new NGS-based technology designed to obtain the complete and specific DNA sequence of a simultaneous number of genes involved in inherited diseases. ...
Chapter 3
... Historically, metazoan animals were subdivided into diploblasts and triploblasts. Diploblasts have two germ layers, the endoderm and the ectoderm, while the triploblasts have a well-defined third germ layer, the mesoderm. This division is based upon the so-called germ layer concept, which has been a ...
... Historically, metazoan animals were subdivided into diploblasts and triploblasts. Diploblasts have two germ layers, the endoderm and the ectoderm, while the triploblasts have a well-defined third germ layer, the mesoderm. This division is based upon the so-called germ layer concept, which has been a ...
Metagenomics
Metagenomics is the study of genetic material recovered directly from environmental samples. The broad field may also be referred to as environmental genomics, ecogenomics or community genomics. While traditional microbiology and microbial genome sequencing and genomics rely upon cultivated clonal cultures, early environmental gene sequencing cloned specific genes (often the 16S rRNA gene) to produce a profile of diversity in a natural sample. Such work revealed that the vast majority of microbial biodiversity had been missed by cultivation-based methods. Recent studies use either ""shotgun"" or PCR directed sequencing to get largely unbiased samples of all genes from all the members of the sampled communities. Because of its ability to reveal the previously hidden diversity of microscopic life, metagenomics offers a powerful lens for viewing the microbial world that has the potential to revolutionize understanding of the entire living world. As the price of DNA sequencing continues to fall, metagenomics now allows microbial ecology to be investigated at a much greater scale and detail than before.