Evolution of Mammalian KELL Blood Group Glycoproteins and
... Endopeptidase Gene Roger S Holmes* Eskitis Institute for Drug Discovery and School of Biomolecular and Physical Sciences, Griffith University, Nathan, QLD, Australia ...
... Endopeptidase Gene Roger S Holmes* Eskitis Institute for Drug Discovery and School of Biomolecular and Physical Sciences, Griffith University, Nathan, QLD, Australia ...
Mechanisms and impact of genetic recombination in the evolution of
... the recent findings on genetic recombination in the pneumococcus from published literature. We provide an overview of the main mechanisms of DNA uptake and exchange that facilitate pneumococcal recombination with other bacteria using WGS. We also discuss the potential biological and clinical impacts ...
... the recent findings on genetic recombination in the pneumococcus from published literature. We provide an overview of the main mechanisms of DNA uptake and exchange that facilitate pneumococcal recombination with other bacteria using WGS. We also discuss the potential biological and clinical impacts ...
E P STUDIO MOLECULAR DE POBLACIONES DE
... aeruginosa isolates from the same geographical area ............................................ 34 Abstract ...........................................................................................................................36 1.1. Introduction ............................................... ...
... aeruginosa isolates from the same geographical area ............................................ 34 Abstract ...........................................................................................................................36 1.1. Introduction ............................................... ...
no correlation between cyp17-34t/c polymorphism and severe acne
... Background: Acne vulgaris is the most common skin condition treated by physician. As a multi factors disease in which many arguments have been raised on the role of heredity in the etiology of acne, the relevant genetic elements in the pathogenesis of the disease are not well established. Objective: ...
... Background: Acne vulgaris is the most common skin condition treated by physician. As a multi factors disease in which many arguments have been raised on the role of heredity in the etiology of acne, the relevant genetic elements in the pathogenesis of the disease are not well established. Objective: ...
Protein Signatures Distinctive of Alpha Proteobacteria and Its
... subgroups (i.e., orders, families, etc.). These signatures were identified by systematic analyses of proteins found in the Rickettsia prowazekii (RP) genome. Conserved indels that are unique to αproteobacteria are present in the following proteins: Cytochrome c oxidase assembly protein Ctag, PurC, D ...
... subgroups (i.e., orders, families, etc.). These signatures were identified by systematic analyses of proteins found in the Rickettsia prowazekii (RP) genome. Conserved indels that are unique to αproteobacteria are present in the following proteins: Cytochrome c oxidase assembly protein Ctag, PurC, D ...
Transfer of DNA from Genetically Modified Organisms (GMOs)
... allow GMOs to function in the environment and then selfdestruct are being developed. ...
... allow GMOs to function in the environment and then selfdestruct are being developed. ...
A Cladistic Analysis of Phenotype Associations with
... Genes that code for products involved in the physiology of a phenotype are logical candidates for explaining interindividual variation in that phenotype. We present a methodology for discovering associations between genetic variation at such candidate loci (assayedthrough restriction endonuclease ma ...
... Genes that code for products involved in the physiology of a phenotype are logical candidates for explaining interindividual variation in that phenotype. We present a methodology for discovering associations between genetic variation at such candidate loci (assayedthrough restriction endonuclease ma ...
Essential Microbiology
... the larvae found on putrefying meat arose from eggs deposited by flies, and not spontaneously as a result of the decay process. This can be seen as the beginning of the end for the spontaneous generation theory, but many still clung to the idea, claiming that while it may not have been true for large ...
... the larvae found on putrefying meat arose from eggs deposited by flies, and not spontaneously as a result of the decay process. This can be seen as the beginning of the end for the spontaneous generation theory, but many still clung to the idea, claiming that while it may not have been true for large ...
SNP discovery
... (1). Third stage filtering: focal points 1 cM intervals across the apple genome, choosing SNPs in 100 kb windows initially based on 712 GDsnp markers (Figure 3) for a total of 842 focal points (2). 6074 SNPs based on focal points + 712 GDsnp + 1652 candidate gene SNPs = 8438 SNPs chosen by this stag ...
... (1). Third stage filtering: focal points 1 cM intervals across the apple genome, choosing SNPs in 100 kb windows initially based on 712 GDsnp markers (Figure 3) for a total of 842 focal points (2). 6074 SNPs based on focal points + 712 GDsnp + 1652 candidate gene SNPs = 8438 SNPs chosen by this stag ...
MAGMA manual (version 1.05)
... gene analysis itself. It is however included for reference in output files, serves as default weight when performing meta-analysis, and will be used to correct for differences in sample size between genes in gene-level analysis (if any). Specifying the gene analysis model A number of different gene ...
... gene analysis itself. It is however included for reference in output files, serves as default weight when performing meta-analysis, and will be used to correct for differences in sample size between genes in gene-level analysis (if any). Specifying the gene analysis model A number of different gene ...
“The only UNG useful in RT-PCR”
... control, is that the enzyme is sufficiently heat-labile to quickly inactivate at the temperatures used for reverse transcription. The easily heat-inactivated Cod UNG makes it possible to use contamination control also in RT-PCR, being able to remove more than 108 copies of contaminating DNA without ...
... control, is that the enzyme is sufficiently heat-labile to quickly inactivate at the temperatures used for reverse transcription. The easily heat-inactivated Cod UNG makes it possible to use contamination control also in RT-PCR, being able to remove more than 108 copies of contaminating DNA without ...
Exploratory data analysis for microarray data
... Which scale, which distance measure to use for clustering? ❍ Data should be normalized and transformed to appropriate scale before clustering (log or generalized log (R package vsn)). ❍ Clustering genes: Standardization of gene vectors or the use of the correlation distance is useful when looking f ...
... Which scale, which distance measure to use for clustering? ❍ Data should be normalized and transformed to appropriate scale before clustering (log or generalized log (R package vsn)). ❍ Clustering genes: Standardization of gene vectors or the use of the correlation distance is useful when looking f ...
Genetic Polymorphism of Human CYP2E1
... a total volume of 35 ml to yield 100- to 200-bp fragments. Subsequently, 15 ml of loading buffer containing 95% formamide, 20 mM EDTA, bromphenol blue, and xylene cyanol FF was added. Just before loading, the samples were heated to 95° for 5 min. Conformation polymorphisms of single-stranded DNA fra ...
... a total volume of 35 ml to yield 100- to 200-bp fragments. Subsequently, 15 ml of loading buffer containing 95% formamide, 20 mM EDTA, bromphenol blue, and xylene cyanol FF was added. Just before loading, the samples were heated to 95° for 5 min. Conformation polymorphisms of single-stranded DNA fra ...
MAGMA manual (version 1.06)
... the p-value file that contains the sample size used per SNP. This option is recommended if such a column is present, especially when analysing SNP meta-analysis results where sample size per SNP can vary considerably. It should be noted that (at present) the specified sample size does not directly a ...
... the p-value file that contains the sample size used per SNP. This option is recommended if such a column is present, especially when analysing SNP meta-analysis results where sample size per SNP can vary considerably. It should be noted that (at present) the specified sample size does not directly a ...
nar-02451-data-e-201
... the association, PubMed Central ID of the article where the sentence is mentioned, PubMed ID of the abstract where the association is mentioned, and a confidence score generated by DEMGD system. The confidence score, which ranges from 0 to 1, is given by the DEMGD classification model, and it indica ...
... the association, PubMed Central ID of the article where the sentence is mentioned, PubMed ID of the abstract where the association is mentioned, and a confidence score generated by DEMGD system. The confidence score, which ranges from 0 to 1, is given by the DEMGD classification model, and it indica ...
The biased nucleotide composition of the HIV genome: a constant
... O (35%, Table 1). Group N and P viruses appear to contain slightly higher (group N) or lower (group P) levels of A-nucleotides, but only one (group P) or no (group N) full-length genomes with long terminal repeats (LTRs) are available for these groups (Table 1). As the LTR is relatively A-poor [5], ...
... O (35%, Table 1). Group N and P viruses appear to contain slightly higher (group N) or lower (group P) levels of A-nucleotides, but only one (group P) or no (group N) full-length genomes with long terminal repeats (LTRs) are available for these groups (Table 1). As the LTR is relatively A-poor [5], ...
Mutualism and asexual reproduction influence recognition genes in a fungal... M.A. van der Nest1, E.T. Steenkamp2, P.M.... Wingfield1 and B. Slippers1*
... (dS) substitution rate ratio (Yang and Nielson, 1998). To test for variation of selective pressures across the codons, goodness of fit was calculated for the different site-specific models proposed by Yang et al. (2000). Statistical significance was calculated with likelihood ratio tests (LRT), whic ...
... (dS) substitution rate ratio (Yang and Nielson, 1998). To test for variation of selective pressures across the codons, goodness of fit was calculated for the different site-specific models proposed by Yang et al. (2000). Statistical significance was calculated with likelihood ratio tests (LRT), whic ...
Characterisation of marsupial PHLDA2 reveals eutherian specific acquisition of imprinting Open Access
... MEST, PEG10, INS and H19, and are from 4 independent domains. We have previously reported that there is no evidence of genomic imprinting of CDKN1C (also known as p57KIP2) in a marsupial, the tammar wallaby (Macropus eugenii) [28,34]. CDKN1C is located in the KCNQ1 domain mapped adjacent to the IGF2 ...
... MEST, PEG10, INS and H19, and are from 4 independent domains. We have previously reported that there is no evidence of genomic imprinting of CDKN1C (also known as p57KIP2) in a marsupial, the tammar wallaby (Macropus eugenii) [28,34]. CDKN1C is located in the KCNQ1 domain mapped adjacent to the IGF2 ...
3. Work strategy
... transcriptome and proteome levels, they can and do have significant effects on the concentrations of numerous individual metabolites. The dynamic metabolite levels in organisms must reflect the exact metabolic phenotypes under different cultural and genetic conditions [58]. While determining the con ...
... transcriptome and proteome levels, they can and do have significant effects on the concentrations of numerous individual metabolites. The dynamic metabolite levels in organisms must reflect the exact metabolic phenotypes under different cultural and genetic conditions [58]. While determining the con ...
Elevated atmospheric CO2 levels affect community structure of rice
... each sample according to the sample-specific multiplex identifier. Low-quality sequences shorter than 300 bp, with an average quality score lower than 25, with mismatching primer sequences, or with ambiguous bases (marked as “N”), were eliminated from downstream analyses. The forward and reverse pri ...
... each sample according to the sample-specific multiplex identifier. Low-quality sequences shorter than 300 bp, with an average quality score lower than 25, with mismatching primer sequences, or with ambiguous bases (marked as “N”), were eliminated from downstream analyses. The forward and reverse pri ...
Ribotyping of Clostridium perfringens from industrially produced
... the reproducibility of a typing method, which is the percentage of strains with the same subtype on repeated testing, preferably after a period of a few months. Second, the discriminatory power of a method is an estimate of its ability to differentiate between two unrelated strains (Hunter 1990; Swa ...
... the reproducibility of a typing method, which is the percentage of strains with the same subtype on repeated testing, preferably after a period of a few months. Second, the discriminatory power of a method is an estimate of its ability to differentiate between two unrelated strains (Hunter 1990; Swa ...
letters - Centre for Social Evolution
... determination function (Fig. 1b). RNAi-induced knockdowns of fem in females result in a developmental switch to entire male head differentiation (Fig. 1b), whereas knockdowns in males do not affect head development. Repressing the function of csd by RNAi results in apparently the same male-like deve ...
... determination function (Fig. 1b). RNAi-induced knockdowns of fem in females result in a developmental switch to entire male head differentiation (Fig. 1b), whereas knockdowns in males do not affect head development. Repressing the function of csd by RNAi results in apparently the same male-like deve ...
Effects of biocides and metals on antibiotic resistance: a
... Background and aim: There is a concern that biocides and metals can co-select for antibiotic resistance. The aim of this thesis is to enhance our understanding of the roles of antibacterial biocides (e.g. antiseptics, disinfectants) and metals (e.g. copper, zinc) in developing, promoting and maintai ...
... Background and aim: There is a concern that biocides and metals can co-select for antibiotic resistance. The aim of this thesis is to enhance our understanding of the roles of antibacterial biocides (e.g. antiseptics, disinfectants) and metals (e.g. copper, zinc) in developing, promoting and maintai ...
Title: Statistical Evidence for Common Ancestry
... distribution under SA and used this to show that proteins yielded much more similar trees than would be expected under the SA model. An underlying assumption of the Penny et al. SA model, which also affects many other statistical tests of common ancestry (Baum et al. 2015), is that there are no func ...
... distribution under SA and used this to show that proteins yielded much more similar trees than would be expected under the SA model. An underlying assumption of the Penny et al. SA model, which also affects many other statistical tests of common ancestry (Baum et al. 2015), is that there are no func ...
Synthesis and isolation of a single-strand
... The low biostability of naked RNA and DNA limits the application in therapeutics. This can be remedied by the introduction of various modifications to the oligonucleotide. These may either improve nuclease resistance, chemical or physical stability, or a combination of these. However, modification o ...
... The low biostability of naked RNA and DNA limits the application in therapeutics. This can be remedied by the introduction of various modifications to the oligonucleotide. These may either improve nuclease resistance, chemical or physical stability, or a combination of these. However, modification o ...
Metagenomics
Metagenomics is the study of genetic material recovered directly from environmental samples. The broad field may also be referred to as environmental genomics, ecogenomics or community genomics. While traditional microbiology and microbial genome sequencing and genomics rely upon cultivated clonal cultures, early environmental gene sequencing cloned specific genes (often the 16S rRNA gene) to produce a profile of diversity in a natural sample. Such work revealed that the vast majority of microbial biodiversity had been missed by cultivation-based methods. Recent studies use either ""shotgun"" or PCR directed sequencing to get largely unbiased samples of all genes from all the members of the sampled communities. Because of its ability to reveal the previously hidden diversity of microscopic life, metagenomics offers a powerful lens for viewing the microbial world that has the potential to revolutionize understanding of the entire living world. As the price of DNA sequencing continues to fall, metagenomics now allows microbial ecology to be investigated at a much greater scale and detail than before.