A large scale analysis of resistance gene
... A. thaliana for resistance to Pseudomonas syringae (gi 15221252), R-gene Mi-1 against nematodes and aphids from Lycopersicon esculentum (gi 7489037) and gene Rpp 8 of A. thaliana (gi 17064876). The sequence of primer RNBS-D-rev was kindly provided by Nevin Young. Primer LM638 was developed by Kanazi ...
... A. thaliana for resistance to Pseudomonas syringae (gi 15221252), R-gene Mi-1 against nematodes and aphids from Lycopersicon esculentum (gi 7489037) and gene Rpp 8 of A. thaliana (gi 17064876). The sequence of primer RNBS-D-rev was kindly provided by Nevin Young. Primer LM638 was developed by Kanazi ...
Autosomal monoallelic expression in the mouse
... variation beyond the phenotypic variation dictated by genotypic variation. Thus, it is important to take into account random monoallelic expression when examining genotype-phenotype correlation. ...
... variation beyond the phenotypic variation dictated by genotypic variation. Thus, it is important to take into account random monoallelic expression when examining genotype-phenotype correlation. ...
human genome research
... biomedicine, biotechnology and health care. It will increase our knowledge not just of single gene disorders such as cystic fibrosis, but also of how genes interact with environmental factors and contribute to a range of other diseases including cancers, heart disease, and diabetes. Once the role of ...
... biomedicine, biotechnology and health care. It will increase our knowledge not just of single gene disorders such as cystic fibrosis, but also of how genes interact with environmental factors and contribute to a range of other diseases including cancers, heart disease, and diabetes. Once the role of ...
Different Species Common Arthritis Quantitative Trait Loci in High
... defined as a QTL. Therefore, the number of susceptibility genes could be much larger than the number of the identified QTLs. On the other hand, identification of susceptibility genes within the QTLs is still a challenging task, with the exceptions of few genes with very strong effect on the disease, ...
... defined as a QTL. Therefore, the number of susceptibility genes could be much larger than the number of the identified QTLs. On the other hand, identification of susceptibility genes within the QTLs is still a challenging task, with the exceptions of few genes with very strong effect on the disease, ...
10709_2015_9875_MOESM4_ESM
... biology, not an artifact. Therefore, while our lists of "slow growth" genes are robust (due to stringent selection criteria); they are probably not completely comprehensive.” In more detail, the authors applied a conservative procedure to restrict the analysis to highly confident HI genes. However, ...
... biology, not an artifact. Therefore, while our lists of "slow growth" genes are robust (due to stringent selection criteria); they are probably not completely comprehensive.” In more detail, the authors applied a conservative procedure to restrict the analysis to highly confident HI genes. However, ...
- GenoSensor Corporation
... After further investigation, it was found that the correlation between this gene and people’s ability to taste PTC was so strong that it could be used in paternity testing, and so it did for many years. Although PTC is not present in the food that we eat, there are other chemical compounds with very ...
... After further investigation, it was found that the correlation between this gene and people’s ability to taste PTC was so strong that it could be used in paternity testing, and so it did for many years. Although PTC is not present in the food that we eat, there are other chemical compounds with very ...
Codon usage and lateral gene transfer in Bacillus subtilis Ivan
... Remarkably, the same details in the translation mechanisms seem to hold true for both B. subtilis and E. coli, indicating an important conservation of the eubacterial translation machinery through 1.2 billion years of divergent evolution. This allows efficient incorporation of horizontally transferr ...
... Remarkably, the same details in the translation mechanisms seem to hold true for both B. subtilis and E. coli, indicating an important conservation of the eubacterial translation machinery through 1.2 billion years of divergent evolution. This allows efficient incorporation of horizontally transferr ...
Imprinting evolution and the price of silence
... DNA methylation and imprint marks Other than typical sequence polymorphisms that do not correlate with imprint status, the nucleotide sequence of the two alleles of imprinted genes are identical. Therefore, the imprint marks that distinguish the two parental alleles must be epigenetic in nature. Epi ...
... DNA methylation and imprint marks Other than typical sequence polymorphisms that do not correlate with imprint status, the nucleotide sequence of the two alleles of imprinted genes are identical. Therefore, the imprint marks that distinguish the two parental alleles must be epigenetic in nature. Epi ...
Chromosome Number
... - Allelic patterns of grandparents will likely to be disrupted in parental gametes with all allelic combinations possible If the three genetic loci occur in close sequence on the chromosome - Crossing over very UNlikely to occur between loci - Allelic patterns of grandparents will likely to be pre ...
... - Allelic patterns of grandparents will likely to be disrupted in parental gametes with all allelic combinations possible If the three genetic loci occur in close sequence on the chromosome - Crossing over very UNlikely to occur between loci - Allelic patterns of grandparents will likely to be pre ...
Deciphering the molecular phylogenetics of the Asian honey bee
... sequence obtained in this study is novel. The partial COI DNA sequence of A. cerana (GenBank Accession No. KM230116) showed 2.72% difference with that of A. cerana (GenBank Accession No. GU191875) isolated from Indonesia and 6.04% difference with A. cerana isolated from Japan (GenBank Accession No. ...
... sequence obtained in this study is novel. The partial COI DNA sequence of A. cerana (GenBank Accession No. KM230116) showed 2.72% difference with that of A. cerana (GenBank Accession No. GU191875) isolated from Indonesia and 6.04% difference with A. cerana isolated from Japan (GenBank Accession No. ...
Genetics_Review_Jeopardy_
... Your doctor tells you that ALL of your children will inherit your allele for brown eye color. This means that you must be ________ for the trait. What is homozygous? ...
... Your doctor tells you that ALL of your children will inherit your allele for brown eye color. This means that you must be ________ for the trait. What is homozygous? ...
Lac A
... Second case: the protein is totally different from the original protein and probably will not be active. (FrameShift Mutation). ...
... Second case: the protein is totally different from the original protein and probably will not be active. (FrameShift Mutation). ...
Genomic Databases for Tomato
... and are available online. Sequence comparisons allow us to identify tomato genes that have no orthologue (counterpart) in these plants. Information on such tomato genes facilitates elucidation of gene functions and metabolic pathways that are characteristic of tomato and the Solanaceae family. Infor ...
... and are available online. Sequence comparisons allow us to identify tomato genes that have no orthologue (counterpart) in these plants. Information on such tomato genes facilitates elucidation of gene functions and metabolic pathways that are characteristic of tomato and the Solanaceae family. Infor ...
Molecular Testing and Clinical Diagnosis
... – On glass slides, hybridization can be detected by fluorescence and spot color detection by a microarray scanner. – The silicone chip consists of electrodes, independently addressable via an electronic control system. Hybridization is detected by changes in resistance. ...
... – On glass slides, hybridization can be detected by fluorescence and spot color detection by a microarray scanner. – The silicone chip consists of electrodes, independently addressable via an electronic control system. Hybridization is detected by changes in resistance. ...
CSE 181 Project guidelines
... T(hyamine) is replaced by U(racil) • Some forms of RNA can form secondary structures by “pairing up” with itself. This can have change its properties • Several types exist, classified by function • mRNA – this is what is usually being referred to when a Bioinformatician says “RNA”. This is used to c ...
... T(hyamine) is replaced by U(racil) • Some forms of RNA can form secondary structures by “pairing up” with itself. This can have change its properties • Several types exist, classified by function • mRNA – this is what is usually being referred to when a Bioinformatician says “RNA”. This is used to c ...
Gene duplications in prokaryotes can be
... are retained. These gene products are likely to be beneficial to the organism, e.g. in adaptation to new environmental conditions. The aim of our analysis is to investigate the properties of paralog-forming genes in prokaryotes, and to analyse the role of these retained paralogs by relating gene pro ...
... are retained. These gene products are likely to be beneficial to the organism, e.g. in adaptation to new environmental conditions. The aim of our analysis is to investigate the properties of paralog-forming genes in prokaryotes, and to analyse the role of these retained paralogs by relating gene pro ...
introduction
... 1992). Additionally, the 6kb linear genome encoded bacterial-type rRNAs which were different from those encoded by the 35kb circle (Feagin et aI., 1997). Sequence analysis revealed that the 35kb element was similar to chloroplast genomes, containing an inverted repeat of ribosomal RNA genes ...
... 1992). Additionally, the 6kb linear genome encoded bacterial-type rRNAs which were different from those encoded by the 35kb circle (Feagin et aI., 1997). Sequence analysis revealed that the 35kb element was similar to chloroplast genomes, containing an inverted repeat of ribosomal RNA genes ...
Molecular evidence for the existence of additional members of the
... remained negative. The typical secondary structure of microbial 165 genes was present in all four new sequences indicating the validity of the sequence data. All four new sequences were distinct from other bacteria and clustered together with known Chlamydiaceae sequences. Phylogenetic analysis sugg ...
... remained negative. The typical secondary structure of microbial 165 genes was present in all four new sequences indicating the validity of the sequence data. All four new sequences were distinct from other bacteria and clustered together with known Chlamydiaceae sequences. Phylogenetic analysis sugg ...
Sex Chromosomes and Sex
... D) Most cases of true hermaphroditism represent chimeras (product of two zygotes) or mosaics (products of two different post-zygotically derived sex chromosome aneuploidies or mutations). II) Pseudoautosomal regions A) Regions with sequence homology between the X and Y chromosomes. B) These regions ...
... D) Most cases of true hermaphroditism represent chimeras (product of two zygotes) or mosaics (products of two different post-zygotically derived sex chromosome aneuploidies or mutations). II) Pseudoautosomal regions A) Regions with sequence homology between the X and Y chromosomes. B) These regions ...
Genomic data mining
... (including 48 programs from the EMBOSS [30] suite, alongside tools for working with genomic sequences, alignments, and functional annotations). The results of analyses in Galaxy are stored remotely in ‘datasets’, which are accessible through the history panel on the right (collapsed in Figure 4). Th ...
... (including 48 programs from the EMBOSS [30] suite, alongside tools for working with genomic sequences, alignments, and functional annotations). The results of analyses in Galaxy are stored remotely in ‘datasets’, which are accessible through the history panel on the right (collapsed in Figure 4). Th ...
Tutorial - Ensembl
... An Ensembl gene may have multiple transcripts reflecting alternative splicing, in this case the EPO gene only shows one transcript in Ensembl. ...
... An Ensembl gene may have multiple transcripts reflecting alternative splicing, in this case the EPO gene only shows one transcript in Ensembl. ...
Lesson Overview
... In males, a defective allele for any of these genes results in colorblindness, an inability to distinguish certain colors. The most common form, red-green colorblindness, occurs in about 1 in 12 males. Among females, however, colorblindness affects only about 1 in 200. In order for a recessive allel ...
... In males, a defective allele for any of these genes results in colorblindness, an inability to distinguish certain colors. The most common form, red-green colorblindness, occurs in about 1 in 12 males. Among females, however, colorblindness affects only about 1 in 200. In order for a recessive allel ...
Human brain evolution: transcripts, metabolites and their regulators
... same two amino acid changes as modern humans in the gene encoding forkhead box P2 (FOXP2)158,159. As these amino acid substitutions have been linked to the evolution of human language160 and changes in brain connectivity110, it is conceivable that Neanderthals and Denisovans also possessed certain t ...
... same two amino acid changes as modern humans in the gene encoding forkhead box P2 (FOXP2)158,159. As these amino acid substitutions have been linked to the evolution of human language160 and changes in brain connectivity110, it is conceivable that Neanderthals and Denisovans also possessed certain t ...
Microsoft Word - Mapping-Traits-in-Dogs
... Ostrander, Ph.D., chief of the Cancer Genetics Branch in NHGRI's Division of Intramural Research. "We think this approach will help pinpoint multiple genes involved in complex human conditions, such as cancer, heart disease, diabetes and obesity." Artificial selection, at the heart of breeding for d ...
... Ostrander, Ph.D., chief of the Cancer Genetics Branch in NHGRI's Division of Intramural Research. "We think this approach will help pinpoint multiple genes involved in complex human conditions, such as cancer, heart disease, diabetes and obesity." Artificial selection, at the heart of breeding for d ...
Human genome
The human genome is the complete set of nucleic acid sequence for humans (Homo sapiens), encoded as DNA within the 23 chromosome pairs in cell nuclei and in a small DNA molecule found within individual mitochondria. Human genomes include both protein-coding DNA genes and noncoding DNA. Haploid human genomes, which are contained in germ cells (the egg and sperm gamete cells created in the meiosis phase of sexual reproduction before fertilization creates a zygote) consist of three billion DNA base pairs, while diploid genomes (found in somatic cells) have twice the DNA content. While there are significant differences among the genomes of human individuals (on the order of 0.1%), these are considerably smaller than the differences between humans and their closest living relatives, the chimpanzees (approximately 4%) and bonobos. Humans share 50% of their DNA with bananas.The Human Genome Project produced the first complete sequences of individual human genomes, with the first draft sequence and initial analysis being published on February 12, 2001. The human genome was the first of all vertebrates to be completely sequenced. As of 2012, thousands of human genomes have been completely sequenced, and many more have been mapped at lower levels of resolution. The resulting data are used worldwide in biomedical science, anthropology, forensics and other branches of science. There is a widely held expectation that genomic studies will lead to advances in the diagnosis and treatment of diseases, and to new insights in many fields of biology, including human evolution.Although the sequence of the human genome has been (almost) completely determined by DNA sequencing, it is not yet fully understood. Most (though probably not all) genes have been identified by a combination of high throughput experimental and bioinformatics approaches, yet much work still needs to be done to further elucidate the biological functions of their protein and RNA products. Recent results suggest that most of the vast quantities of noncoding DNA within the genome have associated biochemical activities, including regulation of gene expression, organization of chromosome architecture, and signals controlling epigenetic inheritance.There are an estimated 20,000-25,000 human protein-coding genes. The estimate of the number of human genes has been repeatedly revised down from initial predictions of 100,000 or more as genome sequence quality and gene finding methods have improved, and could continue to drop further. Protein-coding sequences account for only a very small fraction of the genome (approximately 1.5%), and the rest is associated with non-coding RNA molecules, regulatory DNA sequences, LINEs, SINEs, introns, and sequences for which as yet no function has been elucidated.