MASE1 and MASE2: Two Novel Integral Membrane Sensory Domains
... retxena-Belandia and Engelman, 2001]. The stable structure of the whole domain is probably maintained by the salt bridges between terminal parts of different helices, formed by poorly conserved charged residues (e.g., Asp123, Arg-109). Domain architectures of the MASE1-containing proteins show signi ...
... retxena-Belandia and Engelman, 2001]. The stable structure of the whole domain is probably maintained by the salt bridges between terminal parts of different helices, formed by poorly conserved charged residues (e.g., Asp123, Arg-109). Domain architectures of the MASE1-containing proteins show signi ...
The hnRNP C Proteins Contain a Nuclear Retention Sequence That
... the cytoplasm. These shuttling hnRNP proteins include hnRNP A1, K, and E (Pifiol-Roma and Dreyfuss, 1992, 1993a; Michael et al., 1995b). While in the cytoplasm, hnRNP A1 is associated with mRNA, suggesting that shuttling hnRNP proteins accompany mRNA from the point of its emergence from the transcri ...
... the cytoplasm. These shuttling hnRNP proteins include hnRNP A1, K, and E (Pifiol-Roma and Dreyfuss, 1992, 1993a; Michael et al., 1995b). While in the cytoplasm, hnRNP A1 is associated with mRNA, suggesting that shuttling hnRNP proteins accompany mRNA from the point of its emergence from the transcri ...
Supplementary Figures 1 - 5, Methods
... thereby inhibiting the activation of PLC1(13). The structure of human TRAX, as ...
... thereby inhibiting the activation of PLC1(13). The structure of human TRAX, as ...
Structure of the enzyme-acyl carrier protein (ACP) substrate
... biotin protein ligase (5, 6), which is in contrast to other bacteria where bioH resides within the biotin operon (7). Thus, the E. coli bioH gene may encode a less-specific protein than those encoded by the integrated bioH genes. In this paper we report experiments indicating that BioH acts before Bi ...
... biotin protein ligase (5, 6), which is in contrast to other bacteria where bioH resides within the biotin operon (7). Thus, the E. coli bioH gene may encode a less-specific protein than those encoded by the integrated bioH genes. In this paper we report experiments indicating that BioH acts before Bi ...
Powerpoint - Wishart Research Group
... EWILLITALLCEASE >P12348 Sequence 3 MQWERTGHFDALKPQWERTYHEREISANTHERS... ...
... EWILLITALLCEASE >P12348 Sequence 3 MQWERTGHFDALKPQWERTYHEREISANTHERS... ...
Relationship between Hot Spot Residues and Ligand Binding Hot
... of hot spots identified by alanine scanning mutagenesis versus by small molecule fragment screening, to clarify the relationship between the protein surface sites identified in these different ways, and to gain a better understanding of their implications for the discovery of small molecule inhibitors ...
... of hot spots identified by alanine scanning mutagenesis versus by small molecule fragment screening, to clarify the relationship between the protein surface sites identified in these different ways, and to gain a better understanding of their implications for the discovery of small molecule inhibitors ...
WEEK 10
... nitrogen and carbon comprise more than 99% of living matter. They are the smallest atoms that can attain stable electronic configurations by sharing one, two, three, and four electrons, respectively. All these elements form very stable covalent bonds. Oxygen, nitrogen and carbon form stable multiple ...
... nitrogen and carbon comprise more than 99% of living matter. They are the smallest atoms that can attain stable electronic configurations by sharing one, two, three, and four electrons, respectively. All these elements form very stable covalent bonds. Oxygen, nitrogen and carbon form stable multiple ...
MCB Lecture 2 – Protein Metabolism
... When a normal codon that codes for a particular amino acids is mutated and becomes one of the stop codons (UGA, UAA, UAG) Early termination of the strand o What is a silent mutation? When one of the nucleotides are changed but you still end up with the same amino acid (usually in the 3rd posit ...
... When a normal codon that codes for a particular amino acids is mutated and becomes one of the stop codons (UGA, UAA, UAG) Early termination of the strand o What is a silent mutation? When one of the nucleotides are changed but you still end up with the same amino acid (usually in the 3rd posit ...
analyzing gene and protein sequences
... resources, students can perform many types of analyses on the sequences. Students may search various databases, investigate taxonomy, and perform a number of analyses. For example students can compare human gene/protein sequences to other species’ sequences, simulate restriction analysis, predict se ...
... resources, students can perform many types of analyses on the sequences. Students may search various databases, investigate taxonomy, and perform a number of analyses. For example students can compare human gene/protein sequences to other species’ sequences, simulate restriction analysis, predict se ...
Supplementary Figure 1
... evolution; therefore the branch lengths correspond to amino acid substitutions per time unit. Evidently, UbS27a domains are less conserved than ribosomal S27a domains or homologs to SUMO1, despite the presence of a hypervariable loop at the N-terminus of SUMO1. Particularly indicative of a high rate ...
... evolution; therefore the branch lengths correspond to amino acid substitutions per time unit. Evidently, UbS27a domains are less conserved than ribosomal S27a domains or homologs to SUMO1, despite the presence of a hypervariable loop at the N-terminus of SUMO1. Particularly indicative of a high rate ...
Computer-Based Design of Novel Protein Structures
... Annu. Rev. Biophys. Biomol. Struct. Downloaded from arjournals.annualreviews.org by VIVA on 01/20/06. For personal use only. ...
... Annu. Rev. Biophys. Biomol. Struct. Downloaded from arjournals.annualreviews.org by VIVA on 01/20/06. For personal use only. ...
A metaproteomic assessment of winter and summer
... summer metaproteome, whereas winter was characterized by proteins from ammonia-oxidizing Marine Group I Crenarchaeota. Proteins prevalent in both seasons were from SAR11 and Rhodobacterales clades of Alphaproteobacteria, as well as many lineages of Gammaproteobacteria. The metaproteome data were use ...
... summer metaproteome, whereas winter was characterized by proteins from ammonia-oxidizing Marine Group I Crenarchaeota. Proteins prevalent in both seasons were from SAR11 and Rhodobacterales clades of Alphaproteobacteria, as well as many lineages of Gammaproteobacteria. The metaproteome data were use ...
This is the accepted version of the following article:
... pathological conditions it can be abnormally phosphorylated which leads to aggregation and formation of neurofibrillary tangles representing pathological hallmark of Alzheimer's disease (AD). For its association with neurodegenerative diseases tau protein is intensively studied in various diagnostic ...
... pathological conditions it can be abnormally phosphorylated which leads to aggregation and formation of neurofibrillary tangles representing pathological hallmark of Alzheimer's disease (AD). For its association with neurodegenerative diseases tau protein is intensively studied in various diagnostic ...
Simulation of Enzyme Reaction - diss.fu
... atoms of a molecular system are represented in detail. All electrostatic interactions between the corresponding point charges are then calculated explicitly, such that the electrostatic energy is given by Eq. 2.1. If also all solvent molecules are represented explicitly the dielectric constant can b ...
... atoms of a molecular system are represented in detail. All electrostatic interactions between the corresponding point charges are then calculated explicitly, such that the electrostatic energy is given by Eq. 2.1. If also all solvent molecules are represented explicitly the dielectric constant can b ...
Regulation of Protein Degradation
... and analyses of proteinases. Although studies using heterologous proteins or synthetic peptide substrates will continue to provide valuable information, such studies must at some point utilize in vivo substrates if the physiological roles of proteinases are to be defined. Finally, no particular glob ...
... and analyses of proteinases. Although studies using heterologous proteins or synthetic peptide substrates will continue to provide valuable information, such studies must at some point utilize in vivo substrates if the physiological roles of proteinases are to be defined. Finally, no particular glob ...
The role of mutations in core protein of hepatitis B
... The immunodominant B cell recognition sites within HBcAg have been found around residues 74-89 and 126135 [15,16]. Mutations in both B- and T-cell epitopes associated with viral persistence[16,18] influencing the host immune response and also the natural course of infection [19]. Previous studies sh ...
... The immunodominant B cell recognition sites within HBcAg have been found around residues 74-89 and 126135 [15,16]. Mutations in both B- and T-cell epitopes associated with viral persistence[16,18] influencing the host immune response and also the natural course of infection [19]. Previous studies sh ...
Response of Jujube Fruits to Exogenous Oxalic Acid Treatment
... treatment. In order to determine the details of protein spots in Fig. 5, we magnified the areas of protein spots of interest in Fig. 7A, in which the marked numbers of the protein spots are the same as those in Fig. 5. Fig. 7B shows the abundance of the proteins which are involved in metabolism and e ...
... treatment. In order to determine the details of protein spots in Fig. 5, we magnified the areas of protein spots of interest in Fig. 7A, in which the marked numbers of the protein spots are the same as those in Fig. 5. Fig. 7B shows the abundance of the proteins which are involved in metabolism and e ...
Amino Acid Starter Kit
... 4. Now you can begin to fold your 15-amino acid protein according to the chemical properties of its sidechains. Remember all of these chemical properties affect the protein at the same time! - Start by folding your protein so that all of the hydrophobic sidechains are buried on the inside of your pr ...
... 4. Now you can begin to fold your 15-amino acid protein according to the chemical properties of its sidechains. Remember all of these chemical properties affect the protein at the same time! - Start by folding your protein so that all of the hydrophobic sidechains are buried on the inside of your pr ...
Identification and expression of the first nonmammalian amyloid‐β
... were determined and comparison of the two sequences showed a 94.1% identity within the coding regions. The degree of sequence identity between the Xenopus APLP2-A and APLP2-B proteins was 94% (Fig. 1A). Phylogenetic analysis of the APP superfamily To reveal the evolutionary history of the APP superf ...
... were determined and comparison of the two sequences showed a 94.1% identity within the coding regions. The degree of sequence identity between the Xenopus APLP2-A and APLP2-B proteins was 94% (Fig. 1A). Phylogenetic analysis of the APP superfamily To reveal the evolutionary history of the APP superf ...
Interactome
In molecular biology, an interactome is the whole set of molecular interactions in a particular cell. The term specifically refers to physical interactions among molecules (such as those among proteins, also known as protein-protein interactions) but can also describe sets of indirect interactions among genes (genetic interactions). Mathematically, interactomes are generally displayed as graphs.The word ""interactome"" was originally coined in 1999 by a group of French scientists headed by Bernard Jacq. Though interactomes may be described as biological networks, they should not be confused with other networks such as neural networks or food webs.