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University of Groningen Structure and mechanism of the ECF
University of Groningen Structure and mechanism of the ECF

... but without the additional bioMN (ecfAT) genes. Instead, an operon encoding BioMNhomologues was found at a different location in the genome that was not linked to a gene coding for a substrate specific protein. From this observation it was hypothesized that the BioM like proteins were the elusive en ...
144803525 - BORA
144803525 - BORA

... occur up to the rate at which biological processes takes place in living organisms are regulated by enzymes. The first enzyme to be discovered was “diastase”, now known as “amylase”, by Payen & Persoz in 1833 [1]. In 1926, Sumner demonstrated that enzymes are actually proteins [2], as a result, he w ...
Directions: Choose the BEST answer from among those given.
Directions: Choose the BEST answer from among those given.

Why nature chose phosphate to modify proteins
Why nature chose phosphate to modify proteins

Principles of BIOCHEMISTRY
Principles of BIOCHEMISTRY

(Heterobasidion annosum) in
(Heterobasidion annosum) in

... molecular aspects of the host response to the pathogen infection have been relatively little examined. Typically, plant defence mechanisms comprise preformed and inducible physical and chemical barriers. Preformed physical barriers include thorns, bark and cuticular waxes, and chemical defences comp ...
Nutrient Profile of Renal Specific Formula
Nutrient Profile of Renal Specific Formula

... recommended to restrict fluids (water, coffee, tea, etc.) which is intricately linked with salt/sodium ...
Directional mutational pressure affects the amino acid composition
Directional mutational pressure affects the amino acid composition

... independent contrast test to study the above correlation. Given a rooted phylogenetic tree with n species, a total of n 1 pairwise contrasts can be obtained for each pair of characters X (the genomic GC%) and Y (the amino acid frequency), respectively. Felsenstein (1985) showed that the pairwise con ...
MB ChB PHASE I
MB ChB PHASE I

... a pool of intra- and extra-cellular free amino-acids (kept constant at about 100g). ...
How Translocons Select Transmembrane Helices
How Translocons Select Transmembrane Helices

... 24 April 2008 ...
EF-Tu (elongation factor thermo unstable)
EF-Tu (elongation factor thermo unstable)

... The central dogma of biology is the pathway that starts from a DNA sequence and leads to the formation of a protein; therefore, DNA directs the synthesis of proteins. The process of protein synthesis, also known as translation, can be divided into three steps: initiation, elongation, and termination ...
Midwest climate summary - US Soybean Export Council
Midwest climate summary - US Soybean Export Council

TMEM65 is a mitochondrial inner-membrane protein
TMEM65 is a mitochondrial inner-membrane protein

... complexes due to the scarcity of mitochondrial mRNAs (Sasarman et al., 2010). It has also been reported that LRPPRC associates with the SRA stem-loop-interacting RNA-binding protein (SLIRP), forming a ribonucleoprotein complex (Sasarman et al., 2010). The steroid receptor RNA activator (SRA), a long ...
Novel domains and orthologues of eukaryotic
Novel domains and orthologues of eukaryotic

... In the yeast Saccharomyces cerevisiae at least a dozen factors are known to facilitate elongation through chromatin (3) (Table 1). These are Rad26p, CP (a heterodimeric factor of Cdc68p/Spt16p and Pob3p), Elongator (containing two subcomplexes, each of three subunits), the Spt4p±Spt5p heterodimer an ...
Theory and practice of size exclusion chromatography for
Theory and practice of size exclusion chromatography for

... several possible modifications, such as oxidation, deamination, glycosylation, aggregation, misfolding, or adsorption [8–11]. These modifications could lead to the potential loss of therapeutic efficacy or unwanted immune reactions [7]. Aggregate levels in proteinbased drugs are a critical quality attr ...
Aphelenchoides besseyi
Aphelenchoides besseyi

... Rice white tip nematode, Aphelenchoides besseyi, is a kind of plant parasitic nematodes that cause serious losses in rice and many other crops. Fatty acid and retinoid binding protein (FAR) is a specific protein in nematodes and is related to development, reproduction, infection to the host, and dis ...
A Drosophila Third Chromosome Minute Locus Encodes
A Drosophila Third Chromosome Minute Locus Encodes

... of these, revertant #4, was used for primerextension and Northern analyses (see Figures 4 and 5 ) . Identification of sequences disruptedby insertion of the Pelement: Cloning the DNA surrounding the point of P element insertion was initiated through obtaining the genomic sequence flanking the 5' sid ...
Protein Structure and Interactions
Protein Structure and Interactions

... ATPase activity of Hsp70. Two dnaK genes from the Gram-negative plant pathogen Agrobacterium tumefaciens were amplified and the DnaK proteins (Agt DnaK1 and 2) were over-produced as His-tagged proteins in Escherichia coli. Complementation assays were used to determine if Agt DnaK1 and 2 can functiona ...
Polypeptide Composition of Envelopes of Spinach Chloroplasts
Polypeptide Composition of Envelopes of Spinach Chloroplasts

... branes which were not fully separated from inner envelope membranes. Thirty amino acid residues of the N-terminus of the 15 kDa protein were determined (Fig. 3A). Homology search of the protein against a DNA database revealed that it is homologous to the 16 kDa protein of outer envelopes (OEP16) fro ...
Bioinformatics approaches for functional
Bioinformatics approaches for functional

... functions of membrane proteins have been investigated with several computational approaches, such as developing databases, analyzing the structure ^ function relationship and establishing algorithms to discriminate different type of membrane proteins. However, compilation of bioinformatics resources ...
Amino Acid Profiling and Nucleic Acid
Amino Acid Profiling and Nucleic Acid

1 This exam consists of 5 pages and 15
1 This exam consists of 5 pages and 15

... Protein purification – antibody binds to protein of interest, allowing its purification. Cell labeling – antibody is fluorescent and binds to a cell component, indicating its location Immune system – inactivates pathogens Cancer treatment – antibody carries toxin to a cancer cell Drug detoxification ...
- Wiley Online Library
- Wiley Online Library

Proteins
Proteins

... as we can synthesize them in our bodies. The variable (R) group is this is the only part of the 20 amino acids in human nutrition that is different and unique to each. This side group (R) can be basic, acidic, polar, non-polar, charged, or neutral. The way this side group interacts with other side g ...
Cox, G. Nutritional strategies to maximise recovery following
Cox, G. Nutritional strategies to maximise recovery following

... balance, even when drinks are made freely available and there is little else to distract them from drinking adequately (Carter and Gisolfi 1989). In a real life post-game scenario, when athletes have numerous commitments — cool-down, post-game recovery strategies, media, post-game debrief and functi ...
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Interactome



In molecular biology, an interactome is the whole set of molecular interactions in a particular cell. The term specifically refers to physical interactions among molecules (such as those among proteins, also known as protein-protein interactions) but can also describe sets of indirect interactions among genes (genetic interactions). Mathematically, interactomes are generally displayed as graphs.The word ""interactome"" was originally coined in 1999 by a group of French scientists headed by Bernard Jacq. Though interactomes may be described as biological networks, they should not be confused with other networks such as neural networks or food webs.
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