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Downloadable Full Text - DSpace@MIT
Downloadable Full Text - DSpace@MIT

... dimeric structure of WbpE observed in the crystal structure is confirmed by analytical ultracentrifugation. Analysis of these structures reveals that the active site of the enzyme is composed of residues from both subunits. In particular, we show that a key residue (Arg229), which has previously bee ...
Mitochondrial protein acetylation regulates metabolism
Mitochondrial protein acetylation regulates metabolism

attachment 2 - Food Standards Australia New Zealand
attachment 2 - Food Standards Australia New Zealand

... These analyses did not indicate any differences of biological significance between the seed from soybean DAS-44406-6 and the non-GM control ‘Maverick’. Significant differences were noted in a number of constituents. However, the differences were typically small and all mean values were within both ...
Effect of LIVNITRO on Protein Anabolism
Effect of LIVNITRO on Protein Anabolism

... LivNitro+, Protein anabolism, Total nitrogen excretion, Anthropometric data ...
OMB No. 0925-0001/0002 (Rev. 08/12), Biographical Sketch Format
OMB No. 0925-0001/0002 (Rev. 08/12), Biographical Sketch Format

... came to Stanford in 1998, the program focused on developing a complete technology package for the industrial production of pharmaceutical proteins. The major advance was gaining control over cell-free metabolism. Initially cofactors were added to activate the conversion of pyruvate to acetyl CoA as ...
Predicting the Secondary Structure of Globular Proteins Using
Predicting the Secondary Structure of Globular Proteins Using

Branched-Chain Amino Acids in Exercise
Branched-Chain Amino Acids in Exercise

... Downloaded from jn.nutrition.org by guest on October 10, 2014 ...
Classification and domain analysis of protein
Classification and domain analysis of protein

... further subjected to manual curation to exclude any regulatory proteins that binds to a kinase. The final list of proteins fulfilling the above curation process was classified as true protein kinases and used in this study. All other proteins not having the above properties were filtered and elimina ...
Specific Isotopic Labeling of Methyl Groups has Extended the
Specific Isotopic Labeling of Methyl Groups has Extended the

Norton J Nutr 2006
Norton J Nutr 2006

... leucine to influence directly the rate of muscle protein synthesis, insulin action, and glucose homeostasis. The effects of leucine are, at least in part, associated with the absence of the branched-chain aminotransferase (BCAT) enzyme in liver (15). Absence of BCAT in liver results in an enriched s ...
Limits of adaptation to high dietary protein intakes
Limits of adaptation to high dietary protein intakes

... not suf®cient criterion. In addition there is the need to determine the extent to which the demand for a critical range of functions has been satis®ed. For the system as a whole the demand side is determined by the pattern and rate of protein synthesis and the utilisation of amino acids for other me ...
Amino Acids
Amino Acids

... proteins. • There are more than 20 types of collagens, the most common type is collagen I which constitutes about 90% of cell collagens. • Structure of collagen: three helical polypeptide chains (trimeric) twisted around each other forming triplet-helix molecule. • ⅓ of structure is glycine, 10% pro ...
Antifolding activity of hsp60 couples protein import into the
Antifolding activity of hsp60 couples protein import into the

Chapter 4.32
Chapter 4.32

... traverses the endoplasmic reticulum (ER) and Golgi compartments. In N-glycosylation, a preformed oligosaccharide moiety is transferred en bloc from a long-chain isoprenoid lipid (dolichol) onto the specific N-glycosylation site via an N-glycosidic linkage to the asparagine (Asn) residue of a nascent ...
Structural Investigation of the Antibiotic and ATP
Structural Investigation of the Antibiotic and ATP

... 30, Arg 42 to Gly 46, and Glu 60 to Ala 62 were disordered in the electron density map. These residues are clearly defined in the present model. In the original structure determination of KNTase, there were two large peaks of electron density that were symmetryrelated to one another and were positio ...
Matrix-assisted Laser Desorption/Ionization Mass Spectrometry in
Matrix-assisted Laser Desorption/Ionization Mass Spectrometry in

Molecular evolution of proteins and Phylogenetic Analysis
Molecular evolution of proteins and Phylogenetic Analysis

...  Organisms may contain many highly similar genes, while only one peptide sequence can be identified (e.g. histones, tubulins and GAPDH in humans).  Using these DNA sequences, it would be difficult to decide which are expressed and which not and thus which genes to include in the analysis.  Moreov ...
PDF
PDF

... Shore (1965) in early development of Rana pipiens and R. sylvatica, although some striking changes in these proteins are observed in extracts of homologous organs when tadpoles and frogs of R. catesbeiana are compared (Manwell, 1966). Acid phosphatase, lipase, and N-benzoyl-arginine-naphthylamide ca ...
Document
Document

... different components of the body[2]. Of course, the contribution of these components to whole body protein content differs with carcass protein being the largest contributor to whole body protein. Also, the contribution of the different parts to whole body protein changes over time with an increasin ...
on the importance of cooperativity effects - RSC Publishing
on the importance of cooperativity effects - RSC Publishing

... in avin-dependent enzymes.26 By examining high-resolution structures of proteins and nucleic acids, Chakravarty and coworkers pointed out that “h6”-type anion–p interaction is observed unambiguously and suggested it plays an important role in macromolecular folding and function.27 Howell and cowork ...
Indian Agricultural Research Institute, New Delhi
Indian Agricultural Research Institute, New Delhi

...  Lack of rapid and accurate analytical techniques for small quantities  Negative correlation between grain protein content and yield  Low genetic variability and requirement for accurate analysis  The experience in maize - chalky endosperm, dull appearance and high moisture content of seeds -sus ...
03-232 Biochemistry Exam II - 2013 Name:________________________
03-232 Biochemistry Exam II - 2013 Name:________________________

... i) Briefly discuss the major/general feature(s) of allosteric/cooperative behavior (10 pts), your answer should include a discussion of the properties of the tense (T) and relaxed (R) state. ii) then discuss one of (6 pts): Choice A: how this effect optimizes oxygen delivery to the tissues, Choice B ...
New insight into plant intramembrane proteases
New insight into plant intramembrane proteases

... regions and their characteristic feature is the presence, in their first transmembrane domain, of the HExxH motif, responsible for zinc ion binding. Two other motifs were also shown to be highly conserved in S2P: GpxxN/S/G located within the second TM and the NxxPxxxxDG located in the third TM. The ...
Fast procedure for reconstruction of full
Fast procedure for reconstruction of full

... To efficiently sample protein-conformational space, protein structure prediction algorithms often use a reduced protein representation. For example, instead of calculating interactions between all protein atoms, every amino acid can be represented by a single center of interaction (e.g., positioned o ...
Metabolismus erytrocytů - Univerzita Karlova v Praze
Metabolismus erytrocytů - Univerzita Karlova v Praze

... a major reaction pathway for the consumption of glucose in erythrocytes the specific binding of 2,3-BPG to deoxyhemoglobin decreases the oxygen affinity of hemoglobin and facilites oxygen release in tissues ...
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Interactome



In molecular biology, an interactome is the whole set of molecular interactions in a particular cell. The term specifically refers to physical interactions among molecules (such as those among proteins, also known as protein-protein interactions) but can also describe sets of indirect interactions among genes (genetic interactions). Mathematically, interactomes are generally displayed as graphs.The word ""interactome"" was originally coined in 1999 by a group of French scientists headed by Bernard Jacq. Though interactomes may be described as biological networks, they should not be confused with other networks such as neural networks or food webs.
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