Cox, G. Nutritional strategies to maximise recovery following
... balance, even when drinks are made freely available and there is little else to distract them from drinking adequately (Carter and Gisolfi 1989). In a real life post-game scenario, when athletes have numerous commitments — cool-down, post-game recovery strategies, media, post-game debrief and functi ...
... balance, even when drinks are made freely available and there is little else to distract them from drinking adequately (Carter and Gisolfi 1989). In a real life post-game scenario, when athletes have numerous commitments — cool-down, post-game recovery strategies, media, post-game debrief and functi ...
A Survey of Flexible Protein Binding Mechanisms and their
... genome of 29 eukaryotes have proteins with disordered regions of 40 or more consecutive residues.34 An energy landscape survey of a large database of protein complexes has suggested that w15% of monomers may not fold in the absence of partner proteins.35 Several physiological advantages have been su ...
... genome of 29 eukaryotes have proteins with disordered regions of 40 or more consecutive residues.34 An energy landscape survey of a large database of protein complexes has suggested that w15% of monomers may not fold in the absence of partner proteins.35 Several physiological advantages have been su ...
Controlling subcellular delivery to optimize
... the main goals of our research is to imitate the function of proteins found in nature. Many proteins in signal transduction pathways are localized to one compartment initially, bind to protein partners in the cell (or are signaled by other proteins) and change their location in the cell, leading to ...
... the main goals of our research is to imitate the function of proteins found in nature. Many proteins in signal transduction pathways are localized to one compartment initially, bind to protein partners in the cell (or are signaled by other proteins) and change their location in the cell, leading to ...
An ATPase domain common to prokaryotic cell cycle proteins, sugar
... prokaryotic cell cycle proteins MreB, FtsA, and StbA. These are predicted to have subdomains with the same tertiary structure as the ATPase subdomains Ia and Ha of hexokinase, actin, and Hsc7O, a very similar ATP binding pocket, and the capacity for interdomain hinge motion accompanying functional s ...
... prokaryotic cell cycle proteins MreB, FtsA, and StbA. These are predicted to have subdomains with the same tertiary structure as the ATPase subdomains Ia and Ha of hexokinase, actin, and Hsc7O, a very similar ATP binding pocket, and the capacity for interdomain hinge motion accompanying functional s ...
lncRNA in
... What are lncRNA’s? • Arbitrarily defined as >200bp RNA’s that do not code for protein • Excludes Pseudogenes and Nonsense Mediated Decay products ...
... What are lncRNA’s? • Arbitrarily defined as >200bp RNA’s that do not code for protein • Excludes Pseudogenes and Nonsense Mediated Decay products ...
Proteases: Hydrolysis of Peptide Bonds
... Initiation phase: Caspases activated hierarchically by protein-protein interactions to convert from single chain zymogens to two chain active proteases Propagation phase: Proteolysis of proteins at aspartyl residues. Some of these are pro forms of caspases, some are target proteins Termination Phase ...
... Initiation phase: Caspases activated hierarchically by protein-protein interactions to convert from single chain zymogens to two chain active proteases Propagation phase: Proteolysis of proteins at aspartyl residues. Some of these are pro forms of caspases, some are target proteins Termination Phase ...
Structural Characterization of the GSK
... carbazole moiety of staurosporine interacts with a significantly different angle. A comparison of the two planes reveals a difference in angle of approximately 158. The difference in angle also explains why there are no direct interactions between GSK3b and the glycosidic-ring of staurosporine. This ...
... carbazole moiety of staurosporine interacts with a significantly different angle. A comparison of the two planes reveals a difference in angle of approximately 158. The difference in angle also explains why there are no direct interactions between GSK3b and the glycosidic-ring of staurosporine. This ...
ASM book 1.8.7.20 vgv - BioQUEST Curriculum Consortium
... but may have had a distinct phylogenetic history. Consequently, these bacteria-like organisms may comprise a distinct domain, given the name Archaebacteria, or more simply, Archaea. The name reflects an untested conjecture about their evolutionary status. Recent phylogenetic evidence suggests that t ...
... but may have had a distinct phylogenetic history. Consequently, these bacteria-like organisms may comprise a distinct domain, given the name Archaebacteria, or more simply, Archaea. The name reflects an untested conjecture about their evolutionary status. Recent phylogenetic evidence suggests that t ...
The synthesis of peptides and proteins containing non
... contains Glu78 and Glu172, which lie y5.5 Å apart and function as the active site nucleophile and the general acid catalyst respectively. In previous work a Glu78Asp mutant, where the carboxylate–carboxylate distance is larger than in the wild-type enzyme, was studied, but was found to have little ...
... contains Glu78 and Glu172, which lie y5.5 Å apart and function as the active site nucleophile and the general acid catalyst respectively. In previous work a Glu78Asp mutant, where the carboxylate–carboxylate distance is larger than in the wild-type enzyme, was studied, but was found to have little ...
Microsoft Word
... release of many potential peptides with various biological activities, when hydrolyzed by proteolytic enzymes. The effect of proteolytic enzymes on the release of biologically ...
... release of many potential peptides with various biological activities, when hydrolyzed by proteolytic enzymes. The effect of proteolytic enzymes on the release of biologically ...
Document
... NaCl + e- NaClNaCl NaCl+ + eIt then analyzes those ions to provide information about the molecular weight of the compound and its chemical structure. ...
... NaCl + e- NaClNaCl NaCl+ + eIt then analyzes those ions to provide information about the molecular weight of the compound and its chemical structure. ...
Print - Circulation Research
... cycloheximide, 2.5 /xg/ml, to block protein synthesis and reutilization of label. For experiments involving chloroquine, initial stabilization for all hearts was in control medium, and experimental hearts were exposed to the drug only during the 24hour degradation period. To test the effects of nonm ...
... cycloheximide, 2.5 /xg/ml, to block protein synthesis and reutilization of label. For experiments involving chloroquine, initial stabilization for all hearts was in control medium, and experimental hearts were exposed to the drug only during the 24hour degradation period. To test the effects of nonm ...
Protein design TOPS cartoon of Top7 Approach to designing Top7
... [Kuhlman, B., Dantas, G., Ireton, G.C., Varani, G., Stoddard, B.L. and Baker, D. (2003) Design of a novel globular protein fold with atomiclevel accuracy. Science, 302, 1364-1368] What about folds that are not seen in SCOP or CATH? Some are: • physically impossible; • not yet sampled by evolution; • ...
... [Kuhlman, B., Dantas, G., Ireton, G.C., Varani, G., Stoddard, B.L. and Baker, D. (2003) Design of a novel globular protein fold with atomiclevel accuracy. Science, 302, 1364-1368] What about folds that are not seen in SCOP or CATH? Some are: • physically impossible; • not yet sampled by evolution; • ...
Understanding Tools and Techniques in Protein Structure Prediction
... characteristics of unique features of the protein as well as the identification of similar traits in other proteins. However, it is noteworthy that identifying patterns and functions of proteins are still far from being perfect which are likely to result in false interpretations and assumptions. Hen ...
... characteristics of unique features of the protein as well as the identification of similar traits in other proteins. However, it is noteworthy that identifying patterns and functions of proteins are still far from being perfect which are likely to result in false interpretations and assumptions. Hen ...
THE THREE-DIMENSIONAL STRUCTURE OF PROTEINS
... can theoretically assume countless different conformations, and as a result the unfolded state of a protein is characterized by a high degree of conformational entropy. This entropy, and the hydrogen-bonding interactions of many groups in the polypeptide chain with solvent (water), tend to maintain ...
... can theoretically assume countless different conformations, and as a result the unfolded state of a protein is characterized by a high degree of conformational entropy. This entropy, and the hydrogen-bonding interactions of many groups in the polypeptide chain with solvent (water), tend to maintain ...
Journal of Bacteriology
... with its presence in the growth medium. Furthermore, the protein has a relatively high content of phenylalanine (17 residues) and tyrosine (7 residues) residues. NodO is homologous to part of the hemolysin A protein (HlyA) of E. coli. The amino acid sequence of the NodO protein was compared with the ...
... with its presence in the growth medium. Furthermore, the protein has a relatively high content of phenylalanine (17 residues) and tyrosine (7 residues) residues. NodO is homologous to part of the hemolysin A protein (HlyA) of E. coli. The amino acid sequence of the NodO protein was compared with the ...
Materials and Methods
... Analyses of sequence parameters influencing suitability for NMR structure determination. Nearly 1,000 protein constructs less than 200 amino acids in length that were expressed and soluble at a sufficient level were screened for their suitability for NMR solution-structure determination by the NESG. ...
... Analyses of sequence parameters influencing suitability for NMR structure determination. Nearly 1,000 protein constructs less than 200 amino acids in length that were expressed and soluble at a sufficient level were screened for their suitability for NMR solution-structure determination by the NESG. ...
Onset of lactation in the bovine mammary gland:
... Abstract The mammary gland undergoes dramatic functional and metabolic changes during the transition from late pregnancy to lactation. To better understand the molecular events underlying these changes, we analyzed expression profiles of approximately 23,000 gene transcripts in bovine mammary tissue ...
... Abstract The mammary gland undergoes dramatic functional and metabolic changes during the transition from late pregnancy to lactation. To better understand the molecular events underlying these changes, we analyzed expression profiles of approximately 23,000 gene transcripts in bovine mammary tissue ...
The Structure and Function of Large Biological Molecules
... substance for humans because cellulose is the major constituent of paper and the only component of cotton. Enzymes that digest starch by hydrolyzing its α linkages are unable to hydrolyze the β linkages of cellulose because of the distinctly different shapes of these two molecules. In fact, few orga ...
... substance for humans because cellulose is the major constituent of paper and the only component of cotton. Enzymes that digest starch by hydrolyzing its α linkages are unable to hydrolyze the β linkages of cellulose because of the distinctly different shapes of these two molecules. In fact, few orga ...
Exploring the Effects of Human Cytomegalovirus Infection on Host
... latently infect a majority of the world’s population. Though infections are usually minor, HCMV can cause serious problems in the immunocompromised and is a leading cause of birth defects. When HCMV infects a human cell, it effectively turns the cell into a “virus-producing factory”, taking control ...
... latently infect a majority of the world’s population. Though infections are usually minor, HCMV can cause serious problems in the immunocompromised and is a leading cause of birth defects. When HCMV infects a human cell, it effectively turns the cell into a “virus-producing factory”, taking control ...
Relationship between Protein Synthesis and Secretion in Liver Cells
... The effect of rotenone, 2,4-dinitrophenol, fructose and glycerol on the release into the medium of lactate dehydrogenase and glutamate dehydrogenase, enzymes of the cytoplasm and mitochondria, respectively, was assayed. Enzyme activities were monitored in both total cell suspension and incubation me ...
... The effect of rotenone, 2,4-dinitrophenol, fructose and glycerol on the release into the medium of lactate dehydrogenase and glutamate dehydrogenase, enzymes of the cytoplasm and mitochondria, respectively, was assayed. Enzyme activities were monitored in both total cell suspension and incubation me ...
Interactome
In molecular biology, an interactome is the whole set of molecular interactions in a particular cell. The term specifically refers to physical interactions among molecules (such as those among proteins, also known as protein-protein interactions) but can also describe sets of indirect interactions among genes (genetic interactions). Mathematically, interactomes are generally displayed as graphs.The word ""interactome"" was originally coined in 1999 by a group of French scientists headed by Bernard Jacq. Though interactomes may be described as biological networks, they should not be confused with other networks such as neural networks or food webs.