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Co-evolving residues in membrane proteins
Co-evolving residues in membrane proteins

... at certain positions are used to evaluate the effect of this perturbation on the residue compositions at other positions of the alignment. Independent of the prediction strategy used, most studies on co-evolving residues so far were conducted with soluble proteins. Membrane proteins, which constitut ...
PPT
PPT

medical management: portosystemic vascular anomalies (psva)
medical management: portosystemic vascular anomalies (psva)

... Primary or progressive liver injury important implications. Muscle catabolism also releases amino acids increasing nitrogenous wastes. Nutritional support must be tailored to the individual patient as different magnitudes of shunting seeming influence dietary protein tolerance. Standard strategy use ...
Production of functional protein hydrolysates from Egyptian
Production of functional protein hydrolysates from Egyptian

... Enzymatic hydrolysis is an agro-processing aid that can be utilized in order to improve nutritional quality of protein extracts from many sources. In this study, protein extracts from ungerminated and/or germinated local Egyptian soybean and lupin flours were hydrolyzed using the enzyme papain. The ...
Application Note #14 - GE Healthcare Life Sciences
Application Note #14 - GE Healthcare Life Sciences

... proteinases. Mass spectrometry has recently proven to be an important methodology for characterizing peptides and proteins, particularly when combined with other techniques, such as gel electrophoresis and amino acid sequence analysis [4]. The coupling of SDS-denaturing gel separation of proteins wi ...
The protein acetylome and the regulation of metabolism - Serval
The protein acetylome and the regulation of metabolism - Serval

... (Ard1) subunits, the N-Acetyl Transferase B complex (NatB) contains the subunits N-Acetyl Transferase 3 (Nat3) and Mitochondrial Distribution and Morphology 20 (Mdm20), while the N-Acetyl Transferase C complex (NatC) contains the Maintenance of Killer proteins Mak3, Mak10 and Mak31. Homologs to all ...
Journal of Agricultural and Food Chemistry
Journal of Agricultural and Food Chemistry

... Electrophoretic and functional properties indicated a significant correlation between soluble protein fractions from soybean and amaranth. The protein fractions shared some common electrophoretic bands as well as a similar amino acid composition. The larger percent of denaturation in protein fractio ...
Protein for Athletes
Protein for Athletes

... for prevention and treatment of sarcopenia or age-related loss of muscle and function in older adults.16 ...
6. Proteins
6. Proteins

Open access - Bioinformation
Open access - Bioinformation

... diseasewith varying clinical outcomes, disease progression, and responses to specific treatmentsattributed by a wide array of elements ranging from tumorintrinsic genetic factorstoextrinsic ...
Enzyme changes in malnutrition - Journal of Clinical Pathology
Enzyme changes in malnutrition - Journal of Clinical Pathology

... it is largely empirical. There does not seem to be any particular reason why some enzymes but not others appear in serum in detectable amounts, and one cannot draw any general conclusions from the behaviour of these particular enzyme proteins. We now know that the same dietary stimulus may alter the ...
Research Applications Of Proteolytic Enzymes In Molecular Biology
Research Applications Of Proteolytic Enzymes In Molecular Biology

... the replication of retroviruses [5,6]. Due to their key role in the life-cycle of many hosts and pathogens they have great medical, pharmaceutical, and academic importance [7–9]. It was estimated previously that about 2% of the human genes encode proteolytic enzymes [8] and due to their necessity in ...
Conserved Positions for Ribose Recognition: Importance of Water
Conserved Positions for Ribose Recognition: Importance of Water

... are involved in energy exchange processes in biological systems, whereas FAD, among other dinucleotides, acts as an ancillary electron carrier for a wide variety of enzymes involved in metabolism. Knowledge of the principles that govern ribose recognition by proteins is sketchy because tertiary and ...
LS1a Fall 2014 Lab 2: Computer Modeling of Proteins with PyMOL
LS1a Fall 2014 Lab 2: Computer Modeling of Proteins with PyMOL

... Scientists use these different representations (sticks, space filling, mesh, etc.) depending on their particular needs when studying a molecule. Note that each representation has its own advantages and disadvantages. For example, while the “sticks” representation provides a rather detailed look at a ...
protien notes - davis.k12.ut.us
protien notes - davis.k12.ut.us

... Protein PROTEIN 1. Proteins provide _________ calories per gram. 2. The main function of protein is to ___________________________________________________.  If carbohydrates and fat are not available, your body will use protein. Is this a good thing? _______ 3. You must eat protein _______________ ...
Discovery, Structural Determination, and Putative
Discovery, Structural Determination, and Putative

... limited sequence available for degenerate primer design and the diminutive product produced. Furthermore, the cyclic nature of SFTI-1 complicates primer design because the order in which residues appear in the linear precursor is unknown. Because SFTI-1 is expressed only in seeds, isolation of cDNA ...


... Choice A: Pretend you just finished the Pittsburgh marathon. As a consequence, your glycogen levels and ATP levels in the liver are quite low. Discuss the process, with the major focus on regulation in your answer, by which your glycogen levels and ATP levels are restored as you eat lots of carbohyd ...
Pharmacophore screening of the Protein Data Bank for specific
Pharmacophore screening of the Protein Data Bank for specific

... surface grooves while others form slightly deeper cavities, 10 different Me-Lys binding sites were selected to represent the structural diversity of the so-called aromatic cage system.33 (Fig. 2) Only proteins for which at least one Me-Lys bound co-crystal structure was available were chosen, and fo ...
Statistical analysis of DNA microarray data
Statistical analysis of DNA microarray data

... to fold groups and homologous superfamilies are made by sequence and structure comparisons. ...
Minimal domain of bacterial phytochrome required for chromophore binding and fluorescence
Minimal domain of bacterial phytochrome required for chromophore binding and fluorescence

... a new Cys252 residue became responsible for this function. Our hypothesis was based on the similarity between the position of Cys252 and chromphore-binding Cys residues in the GAF domains of plant and cyanobacterial phytochromes, which utilize reduced tetrapyrrole bilins such as phytochromobilin and ...
Tunicates and not cephalochordates are the closest living relatives
Tunicates and not cephalochordates are the closest living relatives

... grouped with echinoderms, a hypothesis that needs to be tested with additional data. This new phylogenetic scheme prompts a reappraisal of both morphological and palaeontological data and has important implications for the interpretation of developmental and genomic studies in which tunicates and ce ...
Cold Shock Proteins
Cold Shock Proteins

... reported that when temperature decreased, mRNA of CspA increased. This indicates that, the synthesis of this protein is regulated at the level of transcription (32). Ribosomes can act as sensors of the cold shock response in Escherichia coli on the basis of the observation that the cold shock respon ...
Full-Text PDF
Full-Text PDF

... responses comprises the TGA (TGACGTCA cis-element-binding proteins) [5]. In Arabidopsis, there are seven members of the TGA family, and these proteins play roles in plant defense, xenobiotic stress responses and development. A major advance was the discovery that TGA family members interact with an ...
C-terminal Truncation of p21H Preserves Crucial Kinetic and
C-terminal Truncation of p21H Preserves Crucial Kinetic and

... T4 DNA Ligase,polynucleotide kinase, and dNTPswere from Boehringer Mannheim, Federal Republic of Germany. The above reagents were used as described in the laboratory manual of Maniatis et al. (18).Transformation was done according to themethod of Hanahan (19) with frozen cells or according to theCaC ...
Theranostics Evolution- and Structure
Theranostics Evolution- and Structure

... predicted to have little or no effect on protein function, some nsSNPs are known to be associated with disease. These disease-associated nsSNPs have diverse effects on protein properties and may affect a protein’s stability, catalytic activity, and/or interaction with other molecules. Therefore, the ...
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Interactome



In molecular biology, an interactome is the whole set of molecular interactions in a particular cell. The term specifically refers to physical interactions among molecules (such as those among proteins, also known as protein-protein interactions) but can also describe sets of indirect interactions among genes (genetic interactions). Mathematically, interactomes are generally displayed as graphs.The word ""interactome"" was originally coined in 1999 by a group of French scientists headed by Bernard Jacq. Though interactomes may be described as biological networks, they should not be confused with other networks such as neural networks or food webs.
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