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Pattern searches for the identification of putative lipoprotein genes in
Pattern searches for the identification of putative lipoprotein genes in

... Lpp processing enzymes may be subtly different. One exception within this criterion is the Cu,Zn superoxide dismutase Lpp of Mycobacterium tuberculosis where non-denaturing electrophoresis indicated that the native membrane-associated enzyme activity is electrophoretically identical to that which ha ...
Structural and functional features of the intracellular amino
Structural and functional features of the intracellular amino

Molecular analysis of an operon in Bacillus subtilis
Molecular analysis of an operon in Bacillus subtilis

... present. In addition, between the Walker motifs I and 11, EcsA contains a glutamine- and glycine-rich motif (consensus L/FSGGQQ/R/KQR) that is well-conserved in the ATP-binding components of ABC-transporters (Ames e t al., 1992). Homology that extends beyond the ATP-binding motifs was observed betwe ...
human-physiology-ii-lecture-endomembrane
human-physiology-ii-lecture-endomembrane

Proteins in the Diet - Nutrition and Food Technology-just
Proteins in the Diet - Nutrition and Food Technology-just

Regulation of protein synthesis by insulin
Regulation of protein synthesis by insulin

... (tuberous sclerosis complex 1)–TSC2 complex to relieve its inhibitory action on the mTOR (mammalian target of rapamycin). Inhibition of mTOR by rapamycin markedly impairs insulin-activated protein synthesis. mTOR controls translation initiation and elongation. The cap-binding factor eIF4E can be seq ...
Protein Structure
Protein Structure

... color coded. The heme groups are in space filling form ...
Tertiary Structure
Tertiary Structure

lec39_2013 - Andrew.cmu.edu
lec39_2013 - Andrew.cmu.edu

... tRNA: Although it varies, there are generally 25-45 different tRNAs/organism. This complex single chain RNA molecule structure is stabilized by W-C H-bonds, non-W-C H-bonds, and phosphate-metal interactions.  Acceptor stem: amino acids are attached to the 3' terminus of the tRNA by enzymes called a ...
Exploring your protein - QIAGEN Bioinformatics
Exploring your protein - QIAGEN Bioinformatics

... A suitable protein structure of the CLC protein is found and examined with the intent to use it for structure based drug design. Example data relating to this tutorial can be imported from the Help menu ( Help | Import Example Data). The files for this tutorial is found in CLC_Data/Example Data/Expl ...
GFP-labelled Rubisco and aspartate aminotransferase are present
GFP-labelled Rubisco and aspartate aminotransferase are present

... Plastid stromules are membrane-bound protrusions of the plastid envelope that contain soluble stroma. Stromules are often found connecting plastids within a cell and ¯uorescence recovery after photobleaching (FRAP) experiments have demonstrated that green ¯uorescent protein (GFP) can move between pl ...
Iron-sulfur proteins and the role of iron in the gene expression of
Iron-sulfur proteins and the role of iron in the gene expression of

... Iron is an essential nutrient for the parasitic protist Trichomonas vaginalis as a component of iron-sulfur (FeS) proteins that are indispensable for energy metabolism of the parasite. The FeS clusters are formed by FeS cluster (ISC) assembly machinery that resides, together with a number of FeS pro ...
- Journal of Allergy and Clinical Immunology
- Journal of Allergy and Clinical Immunology

... such subjects would provide a high level of confidence that the novel protein was a potential allergen. Foods containing such novel proteins would need to be labeled to protect allergic consumers. dA novel protein with either no sequence similarity to known allergens or derived from a less commonly ...
Chemically Mediated Site-Specific Proteolysis. Alteration of Protein
Chemically Mediated Site-Specific Proteolysis. Alteration of Protein

... of native proteins. One possible application of this new functionality includes the systematic removal of individual protein domains of putative higher order structures such that the functional contribution(s) of these structures can be dissected. Especially in complicated protein-protein complexes, ...
Protein Catabolism
Protein Catabolism

... The biosynthesis of proteins requires a continuous source of amino acids. Amino acids also provide cells with a source of nitrogen for the synthesis of nitrogen containing biomolecules such as nucleotides. Amino acids are generated by the digestion of proteins in the intestine or by the degradation ...
Concept 3.1 Nucleic Acids Are Informational
Concept 3.1 Nucleic Acids Are Informational

... activation energy and speed a reaction. – The active site orients substrates in the correct orientation for the reaction. – As the active site binds the substrate, it may put stress on bonds that must be broken, making it easier to reach the transition state. – R groups at the active site may create ...
basic laboratory course 3
basic laboratory course 3

... A major goal in the modern biology laboratory is the isolation of specific proteins from complex mixtures. Such isolation procedures frequently involve chromatography. Proteins are most often separated by column chromatography, in which a mixture of different proteins is passed through a column or t ...
Fluorescence Study of Bovine β-Lactoglobulin
Fluorescence Study of Bovine β-Lactoglobulin

... Three lifetimes are in general observed for Trp residue(s) in proteins, two of them are inherent to the tryptophan itself independently of the structure surrounding it while the third one is is generated by the interaction between Trp residue(s) and neighboring amino acids. Also, one should consider ...
AlgPred: prediction of allergenic proteins and mapping of
AlgPred: prediction of allergenic proteins and mapping of

... used as an input vector of dimension 20 for training and testing of SVM (33–35). The performance of SVM-based methods has been optimized by tuning SVM parameters, in order to achieve maximum accuracy with nearly equal sensitivity and specificity. As shown in Table 1, we achieved accuracy around 85% ...
Proteomic Analysis of Neisseria gonorrhoeae Biofilms
Proteomic Analysis of Neisseria gonorrhoeae Biofilms

... biofilm, further highlighting the diversified nature of such bacterial communities. Given the importance of biofilm populations to disease, it is critical to better understand the biochemical signals that regulate biofilm formation and maintenance. During the past decade, there have been various gen ...
Health relevance of intestinal protein fermentation in young
Health relevance of intestinal protein fermentation in young

... animal food proteins has been related to the increment in digestibility. Differences in protein digestibility have also been related to the interaction of protein with dietary heat-stable (phytic acid, tannins, calcium, non-starch polysaccharides) and heat-labile compounds (protease inhibitors and l ...
The Classic Ketogenic Diet
The Classic Ketogenic Diet

... sports drinks. Try alternatives such as diet caffeine free soda or sugar free sports drinks ...
Handling Drug / Tube Feeding Interactions
Handling Drug / Tube Feeding Interactions

... interactions at your institution • Describe various techniques for avoiding potential drug / tube feeding interactions • Develop a method for avoiding potential drug / tube feeding interactions when specific recommendations are not available ...
Protein domains as units of genetic transfer
Protein domains as units of genetic transfer

... Fig. 4. Distances between inferred breakpoint and the nearest protein domain boundary based on divergence of recombining sequences: (A) low, (B) moderate and (C) high divergence. The panels of (i) and (ii) show the observed distances and expected distances, respectively. For each graph in (i) and (i ...
Chapter 9
Chapter 9

... 4. Quaternary structure alignment of several tertiary structure into one protein by means of hydrogen bonds, electrostatic, salt bonds Ex: hemoglobin consist of four single strand tertiary. ...
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Interactome



In molecular biology, an interactome is the whole set of molecular interactions in a particular cell. The term specifically refers to physical interactions among molecules (such as those among proteins, also known as protein-protein interactions) but can also describe sets of indirect interactions among genes (genetic interactions). Mathematically, interactomes are generally displayed as graphs.The word ""interactome"" was originally coined in 1999 by a group of French scientists headed by Bernard Jacq. Though interactomes may be described as biological networks, they should not be confused with other networks such as neural networks or food webs.
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