Methodology for predicting semantic annotations of protein
... The framework of this thesis is located in the field of bioinformatics. Particularly in the area associated to machine learning and pattern recognition, where a methodology for predict semantic annotations of proteins based on a robust feature extraction is proposed. The first part of this thesis co ...
... The framework of this thesis is located in the field of bioinformatics. Particularly in the area associated to machine learning and pattern recognition, where a methodology for predict semantic annotations of proteins based on a robust feature extraction is proposed. The first part of this thesis co ...
Structure-Based Prediction of DNA Target Sites by Regulatory Proteins
... promoters and compared with experimental data. These results show that target binding sites for several regulatory proteins are successfully predicted, and our data suggest that this method can serve as a powerful tool for predicting multiple target sites and target genes for regulatory proteins. Pr ...
... promoters and compared with experimental data. These results show that target binding sites for several regulatory proteins are successfully predicted, and our data suggest that this method can serve as a powerful tool for predicting multiple target sites and target genes for regulatory proteins. Pr ...
Supplemental Text
... protected against APAP in the presence of protein adduct formation when given at 1 h after APAP.18 However, there appeared to be some effect on protein binding at this early time point.18 In contrast, Salminen et al. did not detect any effect of NAC on APAP protein adducts when administrated at 1 or ...
... protected against APAP in the presence of protein adduct formation when given at 1 h after APAP.18 However, there appeared to be some effect on protein binding at this early time point.18 In contrast, Salminen et al. did not detect any effect of NAC on APAP protein adducts when administrated at 1 or ...
proteins: three-dimensional structure
... than the 3.6 residues per turn of a standard a helix, the two keratin helices are inclined about 18° relative to one another, resulting in the coiled coil arrangement. This conformation allows the contacting side chains to interdigitate (Fig. 6-14b). The higher order structure of a keratin is not we ...
... than the 3.6 residues per turn of a standard a helix, the two keratin helices are inclined about 18° relative to one another, resulting in the coiled coil arrangement. This conformation allows the contacting side chains to interdigitate (Fig. 6-14b). The higher order structure of a keratin is not we ...
Poster for RCPSC mee.. - University of Alberta
... Reversible protein phosphorylation is an integral mechanism of signal transduction in many important cellular processes, including, but certainly not limited to, mitogenesis, apoptosis, and regulation of gene expression. In the human genome, the ratio of Ser/Thr protein kinases to Ser/Thr protein ph ...
... Reversible protein phosphorylation is an integral mechanism of signal transduction in many important cellular processes, including, but certainly not limited to, mitogenesis, apoptosis, and regulation of gene expression. In the human genome, the ratio of Ser/Thr protein kinases to Ser/Thr protein ph ...
J Molecular Biology 307:939-949, 2001
... analysis, they also contains many more unrelated sequences. In a typical analysis, the aim is to identify similarity between protein (or nucleotide) sequences that code for molecules with the same or similar function. The sequences might be of whole genes, of domains that appear in different genes, ...
... analysis, they also contains many more unrelated sequences. In a typical analysis, the aim is to identify similarity between protein (or nucleotide) sequences that code for molecules with the same or similar function. The sequences might be of whole genes, of domains that appear in different genes, ...
In the light of directed evolution: Pathways of adaptive protein evolution
... deleterious, depending on how they affect the target property. These studies tend to reach remarkably similar conclusions about the fractions of mutations that fall into each of these 3 classifications, despite applying different methodologies to different proteins to optimize different properties. ...
... deleterious, depending on how they affect the target property. These studies tend to reach remarkably similar conclusions about the fractions of mutations that fall into each of these 3 classifications, despite applying different methodologies to different proteins to optimize different properties. ...
Defining the anabolic window of opportunity
... muscle. The reasons for this lack of certainty likely are multi-factorial and may have to do with the differences in study design between these studies. In the studies described above, the subjects varied from completely untrained (20) to recreationally trained (12) to very welltrained (19). The imp ...
... muscle. The reasons for this lack of certainty likely are multi-factorial and may have to do with the differences in study design between these studies. In the studies described above, the subjects varied from completely untrained (20) to recreationally trained (12) to very welltrained (19). The imp ...
Study Questions for Chapter 1 – The Cell
... 4. When plotting the velocity (V) of an enzymatic reaction against the substrate concentration, one sees “saturable” kinetics. That is, at some substrate concentration, the enzyme is functioning at its maximal rate (Vmax) and cannot operate any faster. The substrate concentration that results in ...
... 4. When plotting the velocity (V) of an enzymatic reaction against the substrate concentration, one sees “saturable” kinetics. That is, at some substrate concentration, the enzyme is functioning at its maximal rate (Vmax) and cannot operate any faster. The substrate concentration that results in ...
Linking folding and binding
... identify these folding motifs, which have been termed molecular recognition elements or MoRFs, by bioinformatic analysis of the protein sequence [22]. These recognition motifs can fold into helix, b-strand, or form irregular structure on binding to a target protein. Binding of disordered linear mot ...
... identify these folding motifs, which have been termed molecular recognition elements or MoRFs, by bioinformatic analysis of the protein sequence [22]. These recognition motifs can fold into helix, b-strand, or form irregular structure on binding to a target protein. Binding of disordered linear mot ...
Clathrinmediated transport: assembly required
... clathrin cages and in displacing clathrin from AP2, both of which would potentially facilitate the uncoating process. The long list of identified regulatory proteins also includes Eps 15, synaptotagmin, intersectin and endophilin, among others. Interestingly, most of the proteins described above hav ...
... clathrin cages and in displacing clathrin from AP2, both of which would potentially facilitate the uncoating process. The long list of identified regulatory proteins also includes Eps 15, synaptotagmin, intersectin and endophilin, among others. Interestingly, most of the proteins described above hav ...
Metabolic and physiological interdependencies in the
... Figure 2 Density gradient enrichment of symbiont cells and host components followed by CARD-FISH. (a) Step-wise workflow of the density gradient enrichment method for physical separation of B. azoricus host and symbiont cells. Sampling for tissue-based metaproteomic analysis of whole gill and foot t ...
... Figure 2 Density gradient enrichment of symbiont cells and host components followed by CARD-FISH. (a) Step-wise workflow of the density gradient enrichment method for physical separation of B. azoricus host and symbiont cells. Sampling for tissue-based metaproteomic analysis of whole gill and foot t ...
Nomenclature of the ARID family of DNA
... Fig. 3. Alignment of the mouse, dog, and human ARID domains. The alignment was created from translation of reported mouse (Mus musculus) and human (Homo sapiens) cDNA sequences, as well as from predicted ARID-containing gene sequences available from the dog (Canis familiaris) genome. In each of thes ...
... Fig. 3. Alignment of the mouse, dog, and human ARID domains. The alignment was created from translation of reported mouse (Mus musculus) and human (Homo sapiens) cDNA sequences, as well as from predicted ARID-containing gene sequences available from the dog (Canis familiaris) genome. In each of thes ...
Production of Polyclonal Antibodies against Sucrose Transporter
... amount of sucrose which could be accumulated in plants [1]. Considering the importance of protein role in sucrose translocation, some researchers succesfully isolated cDNA-SUT from different kinds of plants, such as potatoes and tomatoes [2], tobacco [1], Arabidopsis [3], rice [4] and sugarcane plan ...
... amount of sucrose which could be accumulated in plants [1]. Considering the importance of protein role in sucrose translocation, some researchers succesfully isolated cDNA-SUT from different kinds of plants, such as potatoes and tomatoes [2], tobacco [1], Arabidopsis [3], rice [4] and sugarcane plan ...
Structural genomics of proteins from conserved biochemical
... homology modeling and functional annotation published by two such programs have provided insight into the evolution and function of enzymes in the isoprenoid biosynthesis and ribulose monophosphate pathways. ...
... homology modeling and functional annotation published by two such programs have provided insight into the evolution and function of enzymes in the isoprenoid biosynthesis and ribulose monophosphate pathways. ...
Outsmart Cancer, Eliminate Poisonous Toxins, Boost Antioxidant
... For the cancer patient, whey protein powder can be a lifesaving food. It is well known that cancer aggressively consumes proteins, leaving the rest of the body to starving for optimal amounts of this vital nutrient. Many anti-cancer diets have found that a mostly vegetarian diet is essential to heal ...
... For the cancer patient, whey protein powder can be a lifesaving food. It is well known that cancer aggressively consumes proteins, leaving the rest of the body to starving for optimal amounts of this vital nutrient. Many anti-cancer diets have found that a mostly vegetarian diet is essential to heal ...
311-320 - CiteSeerX
... 325 nm fluorescence emission is due to the buried tryptophan residues (Teale, 1960); quenching of the fluorescence is due to the exposure of the buried tryptophan residues. Thus the first event in the denaturation reaction appears to be perturbation of the aromatic amino acid residues. This is follo ...
... 325 nm fluorescence emission is due to the buried tryptophan residues (Teale, 1960); quenching of the fluorescence is due to the exposure of the buried tryptophan residues. Thus the first event in the denaturation reaction appears to be perturbation of the aromatic amino acid residues. This is follo ...
Narcissus pseudonarcissus L. `Dutch Master`
... compared the abundance of the isolated sequences in the tepals of D1 and D4 flowers confirmed that many of the sequences (or closely related homologs) were more highly expressed in D4 flowers (data not shown). These sequences are indicated in Table 1 by an asterisk. Conventional RNA gel blot analysi ...
... compared the abundance of the isolated sequences in the tepals of D1 and D4 flowers confirmed that many of the sequences (or closely related homologs) were more highly expressed in D4 flowers (data not shown). These sequences are indicated in Table 1 by an asterisk. Conventional RNA gel blot analysi ...
chapter 11
... Orient the peptide structures below to show how they would form hydrogen bonds, and add dashes to show the corresponding hydrogen bonds. Label the partial positive and negative charges in the atoms involved in hydrogen bonding. Why are there partial charges? ...
... Orient the peptide structures below to show how they would form hydrogen bonds, and add dashes to show the corresponding hydrogen bonds. Label the partial positive and negative charges in the atoms involved in hydrogen bonding. Why are there partial charges? ...
Interactome
In molecular biology, an interactome is the whole set of molecular interactions in a particular cell. The term specifically refers to physical interactions among molecules (such as those among proteins, also known as protein-protein interactions) but can also describe sets of indirect interactions among genes (genetic interactions). Mathematically, interactomes are generally displayed as graphs.The word ""interactome"" was originally coined in 1999 by a group of French scientists headed by Bernard Jacq. Though interactomes may be described as biological networks, they should not be confused with other networks such as neural networks or food webs.