Immunophilins and Parvulins. Superfamily of
... function of immunophilins is poorly understood in any organism. In this study, we have surveyed the genes encoding immunophilins in Arabidopsis genome. A total of 52 genes have been found to encode putative immunophilins, among which 23 are putative FKBPs and 29 are putative CYPs. This is by far the ...
... function of immunophilins is poorly understood in any organism. In this study, we have surveyed the genes encoding immunophilins in Arabidopsis genome. A total of 52 genes have been found to encode putative immunophilins, among which 23 are putative FKBPs and 29 are putative CYPs. This is by far the ...
Actin
... At rest, tropomyosin molecules lie on top of the actin active sites, inhibiting interaction between actin and myosin each tropomyosin covers about seven active sites ...
... At rest, tropomyosin molecules lie on top of the actin active sites, inhibiting interaction between actin and myosin each tropomyosin covers about seven active sites ...
A General Method Applicable to the Search for Similarities in the
... are followed, the maximum match mill be the same. The cells of the array whi& contributed to the maximum match, may be determined by recording the origin of the number that mas added to each cell when the array was operated upon. 3. Evaluating the Significance of the Maximum Match A given maximum ma ...
... are followed, the maximum match mill be the same. The cells of the array whi& contributed to the maximum match, may be determined by recording the origin of the number that mas added to each cell when the array was operated upon. 3. Evaluating the Significance of the Maximum Match A given maximum ma ...
Protein structure
... elsewhere. Over the past 75 years or so these early misconceptions have been replaced by an appreciation of the importance of proteins as the ‘molecular workhorses’ of the cell. In 1926, James Sumner showed that urease from jack beans could be highly purified by crystallization, enabling him to demo ...
... elsewhere. Over the past 75 years or so these early misconceptions have been replaced by an appreciation of the importance of proteins as the ‘molecular workhorses’ of the cell. In 1926, James Sumner showed that urease from jack beans could be highly purified by crystallization, enabling him to demo ...
α-Hemolysin pore formation into a supported
... The interaction of cell-free synthesized G-protein coupled receptors with a planar phospholipid bilayer was described qualitatively [4]. Integral membrane proteins were directly inserted into the lipidic bilayer of small unilamellar vesicles [5,6]. These works represent considerable technical advanc ...
... The interaction of cell-free synthesized G-protein coupled receptors with a planar phospholipid bilayer was described qualitatively [4]. Integral membrane proteins were directly inserted into the lipidic bilayer of small unilamellar vesicles [5,6]. These works represent considerable technical advanc ...
Influence of electrostatic interaction on fibrinogen adsorption on gold
... charge of the protein and the solid surface. The pH variation can control the total charge of the protein; on the other hand, the solid surface is modified chemically [2,20,21] or controlled by electrochemical methods [22–34] to change the charge. When the surface charge is changed by chemical modif ...
... charge of the protein and the solid surface. The pH variation can control the total charge of the protein; on the other hand, the solid surface is modified chemically [2,20,21] or controlled by electrochemical methods [22–34] to change the charge. When the surface charge is changed by chemical modif ...
Protein Modeling
... hetero compounds present in this protein, DP9799 and DP9800. They have the same structure. The first 4 parts of this project is looking a proper protein and using DSV program to display, view, and separate the desired hetero-compound from the protein. The most important element in these first parts ...
... hetero compounds present in this protein, DP9799 and DP9800. They have the same structure. The first 4 parts of this project is looking a proper protein and using DSV program to display, view, and separate the desired hetero-compound from the protein. The most important element in these first parts ...
03-232 Exam 1 – S2016 Name:____________________
... Choice A: A 0.1 M solution of glycine (volume = 0.5 L) is at pH = 3.0. How many moles of acid (HCl) would you add to adjust the pH to 2.0? Please show your calculations. Choice B: You want to make a 0.1 M buffer using glycine with a pH = 9.0, total volume of 0.5 L. You only have the fully protonated ...
... Choice A: A 0.1 M solution of glycine (volume = 0.5 L) is at pH = 3.0. How many moles of acid (HCl) would you add to adjust the pH to 2.0? Please show your calculations. Choice B: You want to make a 0.1 M buffer using glycine with a pH = 9.0, total volume of 0.5 L. You only have the fully protonated ...
Structural Basis of Perturbed pKa Values of Catalytic Groups in
... because the values for the amino acids listed in this table are not necessarily appropriate. The best values would be for the side chains appearing in small peptides, so that the α-amino and carboxylate groups do not interact internally with the ionizing group. However, placement of an ionizable gro ...
... because the values for the amino acids listed in this table are not necessarily appropriate. The best values would be for the side chains appearing in small peptides, so that the α-amino and carboxylate groups do not interact internally with the ionizing group. However, placement of an ionizable gro ...
Stabilization by GroEL, a Molecular Chaperone, and a Periplasmic
... The terminal reductase of such respiration, DMSO reductase (DMSOR), is a soluble periplasmic protein consisting of a single polypeptide and containing one molecule of a molybdenum (Mo) cofactor per molecule (Satoh et al. 1987). DMSOR is synthesized as a precursor, with a molecular mass of 89,206 Da. ...
... The terminal reductase of such respiration, DMSO reductase (DMSOR), is a soluble periplasmic protein consisting of a single polypeptide and containing one molecule of a molybdenum (Mo) cofactor per molecule (Satoh et al. 1987). DMSOR is synthesized as a precursor, with a molecular mass of 89,206 Da. ...
Chapter 5 Macromolecules
... • The polysaccharide cellulose is a major component of the tough wall of plant cells • Like starch, cellulose is a polymer of glucose, but the glycosidic linkages differ • The difference is based on two ring forms for glucose: alpha () and beta () ...
... • The polysaccharide cellulose is a major component of the tough wall of plant cells • Like starch, cellulose is a polymer of glucose, but the glycosidic linkages differ • The difference is based on two ring forms for glucose: alpha () and beta () ...
SGKB
... Protein Networks and Biological Systems: enzymatic pathways and networks information Literature: synonyms for protein names, links to PubMed by database identifier and related text and authors Information from more than 50 external annotation resources SGKB ...
... Protein Networks and Biological Systems: enzymatic pathways and networks information Literature: synonyms for protein names, links to PubMed by database identifier and related text and authors Information from more than 50 external annotation resources SGKB ...
Intrinsically Disordered Domains of the B Cell Receptor
... A long-standing belief has been that the functional properties of proteins depend upon their three-dimensional structure, the so-called structurefunction paradigm [9]. The primary origin for this paradigm was the "lockand-key" model (Emil Fischer 1894), which suggested a strict geometric complementa ...
... A long-standing belief has been that the functional properties of proteins depend upon their three-dimensional structure, the so-called structurefunction paradigm [9]. The primary origin for this paradigm was the "lockand-key" model (Emil Fischer 1894), which suggested a strict geometric complementa ...
Folie 1 - FLI
... Structural genomics consists in the determination of the three dimensional structure of all proteins of a given organism, by experimental methods such as X-ray crystallography, NMR spectroscopy or computational approaches such as homology modelling. As opposed to traditional structural biology, the ...
... Structural genomics consists in the determination of the three dimensional structure of all proteins of a given organism, by experimental methods such as X-ray crystallography, NMR spectroscopy or computational approaches such as homology modelling. As opposed to traditional structural biology, the ...
Studying Protein Flexibility in a Statistical Framework: Tools and
... describing and comparing protein conformations were found quite useful for treating large structures. Some of these effectively compare the respective distance matrices of each structure, trying to minimize the difference in intra-atomic distances for selected aligned substructures60,61,74. Other me ...
... describing and comparing protein conformations were found quite useful for treating large structures. Some of these effectively compare the respective distance matrices of each structure, trying to minimize the difference in intra-atomic distances for selected aligned substructures60,61,74. Other me ...
Investigation of a Zα-like Peptide Motif in Koi Herpesvirus
... protein causes an immediate inversion of CD bands from 250-265 nm, whereas in the wild type, inversion did not occur until titration to the ratio of 1:3. At a ratio of 1:5, the highest peak is observed at about 275 nm, whereas in the wild type, the greatest peak was consistently around 280 nm and me ...
... protein causes an immediate inversion of CD bands from 250-265 nm, whereas in the wild type, inversion did not occur until titration to the ratio of 1:3. At a ratio of 1:5, the highest peak is observed at about 275 nm, whereas in the wild type, the greatest peak was consistently around 280 nm and me ...
Protein oxidation and cellular homeostasis: Emphasis
... GSH-Px is an antioxidant enzyme which, in contrast to CAT, works in the cytosol and mitochondria. GSH-Px removes hydrogen peroxide by oxidizing reduced glutathione to oxidized glutathione (GSSG) (Fig. 1C). The GSH-Px family consists of four selenoproteins characterized by differences in localization ...
... GSH-Px is an antioxidant enzyme which, in contrast to CAT, works in the cytosol and mitochondria. GSH-Px removes hydrogen peroxide by oxidizing reduced glutathione to oxidized glutathione (GSSG) (Fig. 1C). The GSH-Px family consists of four selenoproteins characterized by differences in localization ...
Investigation of Iron-Sulfur Protein Maturation in Eukaryotes
... assays to the analysis of mammalian cells. Subheading 3.1. describes our standard methods for analyzing the de novo synthesis of Fe-S cofactors on cellular Fe-S apo-proteins by radiolabeling of cells with 55Fe in vivo. The labeled 55Fe-S proteins of interest are subsequently isolated by immunoprecip ...
... assays to the analysis of mammalian cells. Subheading 3.1. describes our standard methods for analyzing the de novo synthesis of Fe-S cofactors on cellular Fe-S apo-proteins by radiolabeling of cells with 55Fe in vivo. The labeled 55Fe-S proteins of interest are subsequently isolated by immunoprecip ...
FYVE-Dependent Endosomal Targeting of an Arrestin
... discoideum (Figure 1A–B). Arrestin-domain containing proteins extended with a FYVE domain were also found in D. purpureum, Polysphondylium pallidum, Entamoeba histolytica and E. dispar, other members of the Conosea group within the Amoebozoa supergroup to which belongs D. discoideum. Interestingly, ...
... discoideum (Figure 1A–B). Arrestin-domain containing proteins extended with a FYVE domain were also found in D. purpureum, Polysphondylium pallidum, Entamoeba histolytica and E. dispar, other members of the Conosea group within the Amoebozoa supergroup to which belongs D. discoideum. Interestingly, ...
In vitro gastrointestinal digestion study of a novel bio-tofu
... residues of protein bound glutamine and lysine (Hsieh et al., 2014). Soy proteins and caseins are known to be good substrates for MTGase. Enzymatic modification of proteins by MTGase provides protein to distribute more homogeneously and evenly in network which increases the gel stability and in turn ...
... residues of protein bound glutamine and lysine (Hsieh et al., 2014). Soy proteins and caseins are known to be good substrates for MTGase. Enzymatic modification of proteins by MTGase provides protein to distribute more homogeneously and evenly in network which increases the gel stability and in turn ...
Receptors and Hormone Action
... by acting at the cell surface and not only longer-term effects on gene transcription by binding to intracellular receptors ...
... by acting at the cell surface and not only longer-term effects on gene transcription by binding to intracellular receptors ...
Interactome
In molecular biology, an interactome is the whole set of molecular interactions in a particular cell. The term specifically refers to physical interactions among molecules (such as those among proteins, also known as protein-protein interactions) but can also describe sets of indirect interactions among genes (genetic interactions). Mathematically, interactomes are generally displayed as graphs.The word ""interactome"" was originally coined in 1999 by a group of French scientists headed by Bernard Jacq. Though interactomes may be described as biological networks, they should not be confused with other networks such as neural networks or food webs.