
University of Groningen Cross-linking of dimeric CitS and GltS
... Sodium Symporter (ESS; TC 2.A.27) family. Members of the 2HCT and ESS families are found exclusively in bacteria. No sequence homology can be detected between members from the two families, but both families are found in the same structural class ST[3] of the MemGen classification (Lolkema and Slotbo ...
... Sodium Symporter (ESS; TC 2.A.27) family. Members of the 2HCT and ESS families are found exclusively in bacteria. No sequence homology can be detected between members from the two families, but both families are found in the same structural class ST[3] of the MemGen classification (Lolkema and Slotbo ...
The Three-dimensional Structure of 4-Hydroxybenzoyl
... Presently, little is known concerning the evolutionary history of these 4-chlorobenzoate degrading enzymes. The exposure of bacteria to such compounds could have first occurred with the introduction of synthetic chlorinated aromatics into the environment and thus, the acquisition of the 4-chlorobenz ...
... Presently, little is known concerning the evolutionary history of these 4-chlorobenzoate degrading enzymes. The exposure of bacteria to such compounds could have first occurred with the introduction of synthetic chlorinated aromatics into the environment and thus, the acquisition of the 4-chlorobenz ...
Print
... 92: 537–576, 2012; doi:10.1152/physrev.00027.2011.—Protein folding is a complex, error-prone process that often results in an irreparable protein by-product. These by-products can be recognized by cellular quality control machineries and targeted for proteasome-dependent degradation. The folding of ...
... 92: 537–576, 2012; doi:10.1152/physrev.00027.2011.—Protein folding is a complex, error-prone process that often results in an irreparable protein by-product. These by-products can be recognized by cellular quality control machineries and targeted for proteasome-dependent degradation. The folding of ...
article in press - Biochemistry
... extremely useful in delineating these pathways. In this review, we discuss only the sensing and response to macronutrients, particularly glucose, amino acids and fatty acids, or the products of their catabolism. Five pathways were chosen: AMP kinase, mTOR, PAS kinase, hexosamine and Sir2. With the p ...
... extremely useful in delineating these pathways. In this review, we discuss only the sensing and response to macronutrients, particularly glucose, amino acids and fatty acids, or the products of their catabolism. Five pathways were chosen: AMP kinase, mTOR, PAS kinase, hexosamine and Sir2. With the p ...
exam1ans_2007 - algebra
... interactions. 6. (6 pts) Please do either of the following four choices. Please circle your choice: Choice A: Briefly describe the term “quaternary structure”. Provide an example of one. Choice B: What are super-secondary structures? Give an example. Choice C: Distinguish between the secondary and t ...
... interactions. 6. (6 pts) Please do either of the following four choices. Please circle your choice: Choice A: Briefly describe the term “quaternary structure”. Provide an example of one. Choice B: What are super-secondary structures? Give an example. Choice C: Distinguish between the secondary and t ...
Sulfur Metabolism in Escherichia coli and Related Bacteria: Facts
... hydrogen sulfide, H2S. These systems are often poorly known. However, one knows that, for example, thiosulfate can be an excellent sulfur source in E. coli (Sirko et al., 1995). In the same way we do not know much about the use of organic sulfur sources. Biosynthesis of Cysteine The reaction catalyz ...
... hydrogen sulfide, H2S. These systems are often poorly known. However, one knows that, for example, thiosulfate can be an excellent sulfur source in E. coli (Sirko et al., 1995). In the same way we do not know much about the use of organic sulfur sources. Biosynthesis of Cysteine The reaction catalyz ...
Glucose Polyester Biosynthesis. Purification and
... relatively high. Thus, the 108% yield was most likely caused by variability in measurement rather than being an indication of the existence of inhibitors. DEAE chromatography separated the activity from the bulk of the protein and resulted in an approximately 5-fold increase in specific activity (Fi ...
... relatively high. Thus, the 108% yield was most likely caused by variability in measurement rather than being an indication of the existence of inhibitors. DEAE chromatography separated the activity from the bulk of the protein and resulted in an approximately 5-fold increase in specific activity (Fi ...
Characterization of Low Molecular Weight Glutenin Subunits by
... doughs and probably in determining variations in the breadmaking quality of different wheat cultivars (Bietz et al 1973, Payne et al 1984, Hoseney and Rogers 1990). The mechanisms responsible are not completely understood at the molecular level, but the joining together of protein subunits into poly ...
... doughs and probably in determining variations in the breadmaking quality of different wheat cultivars (Bietz et al 1973, Payne et al 1984, Hoseney and Rogers 1990). The mechanisms responsible are not completely understood at the molecular level, but the joining together of protein subunits into poly ...
The Organellar Genome and Metabolic Potential
... approach, the major part of this genome (41,666 bp) has been sequenced and reconstructed as a single contig. This part of the organellar genome contains an almost complete set of genes found in the mitochondrial genomes of other ciliates (table 1, fig. 1). In addition, we found a stretch larger than ...
... approach, the major part of this genome (41,666 bp) has been sequenced and reconstructed as a single contig. This part of the organellar genome contains an almost complete set of genes found in the mitochondrial genomes of other ciliates (table 1, fig. 1). In addition, we found a stretch larger than ...
Identification of a structural motif that confers specific interaction with
... To identify novel COP1-interacting proteins, we used fulllength COP1 protein fused to the Gal4 DNA-binding domain (Gal4-BD) to screen a library made from 3-dayold dark-grown Arabidopsis seedlings (Kim et al., 1997). Fourteen of ~170 000 independent transformants allowed auxotrophic growth and showed ...
... To identify novel COP1-interacting proteins, we used fulllength COP1 protein fused to the Gal4 DNA-binding domain (Gal4-BD) to screen a library made from 3-dayold dark-grown Arabidopsis seedlings (Kim et al., 1997). Fourteen of ~170 000 independent transformants allowed auxotrophic growth and showed ...
Nutrition, Anabolism, and the Wound Healing Process: An Overview
... will always have a preexisting loss, which needs to be added as part of total. One can assume that with any stress-induced PEM, LBM loss is about half of the involuntary weight loss. The relationship between LBM and wound healing is based on the manner of utilization of available protein for either ...
... will always have a preexisting loss, which needs to be added as part of total. One can assume that with any stress-induced PEM, LBM loss is about half of the involuntary weight loss. The relationship between LBM and wound healing is based on the manner of utilization of available protein for either ...
Classification of pseudo pairs between nucleotide bases and amino
... H(U) . . . O(Gln) hydrogen bonds was found in our data set of nucleotide–protein complexes. Since cytosine has a nitrogen and an amino group at Positions 3 and 4, respectively, it may be possible to form the Watson–Crick pseudo pairs with Asn and Gln through N3(C) . . . H–N(Asn/Gln) and N4–H(C) . . ...
... H(U) . . . O(Gln) hydrogen bonds was found in our data set of nucleotide–protein complexes. Since cytosine has a nitrogen and an amino group at Positions 3 and 4, respectively, it may be possible to form the Watson–Crick pseudo pairs with Asn and Gln through N3(C) . . . H–N(Asn/Gln) and N4–H(C) . . ...
Chapter 6: Metal induced selectivity in phosphate ion binding in
... three domains: a translocation domain, a receptor binding domain and the aforementioned DNase domain. The DNase domain can be isolated as an active enzyme. A large number of biochemical and structural studies have been carried out previously on these homologous DNase colicins (1, 2). For instance, X ...
... three domains: a translocation domain, a receptor binding domain and the aforementioned DNase domain. The DNase domain can be isolated as an active enzyme. A large number of biochemical and structural studies have been carried out previously on these homologous DNase colicins (1, 2). For instance, X ...
Simultaneous Alignment and Folding of Protein Sequences
... outperforms state-of-the-art pairwise sequence alignment tools in the most difficult low sequence homology case and improves secondary structure prediction where current approaches fail. Importantly, partiFoldAlign requires no prior training. These general techniques are widely applicable to many mo ...
... outperforms state-of-the-art pairwise sequence alignment tools in the most difficult low sequence homology case and improves secondary structure prediction where current approaches fail. Importantly, partiFoldAlign requires no prior training. These general techniques are widely applicable to many mo ...
STRUCTURAL INSIGHTS INTO NOVEL MICROBIAL METALLOENZYMES
... sources. Structural homology of YcfD, the second metalloenzyme, to the 2OG oxygenase family, particularily human proteins involved in ribosome assembly, combined with evidence that YcfD interacts with the essential ribosomal protein L-16 provides the first evidence of translational regulation by a 2 ...
... sources. Structural homology of YcfD, the second metalloenzyme, to the 2OG oxygenase family, particularily human proteins involved in ribosome assembly, combined with evidence that YcfD interacts with the essential ribosomal protein L-16 provides the first evidence of translational regulation by a 2 ...
Towards the construction of Escherichia coli cell
... Cell-free protein systems are described as the in vitro expression of recombinant proteins without the use of living cells. This approach uses a cell lysate containing a wide array of biological and chemical components for transcription, translation, protein folding, and energy metabolism; all requi ...
... Cell-free protein systems are described as the in vitro expression of recombinant proteins without the use of living cells. This approach uses a cell lysate containing a wide array of biological and chemical components for transcription, translation, protein folding, and energy metabolism; all requi ...
... ii) Sketch the titration curve for a segment of double stranded DNA that is 10 nucleotides long. Be sure to indicate the number of equivalents on the x-axis. (5 pts) iii) Sketch a graph of the TM for double stranded DNA as a function of pH. Justify your answer with a discussion which molecular force ...
A 1-Megadalton Translocation Complex Containing
... located in the inner and outer envelope membranes. At the inner membrane, many Tic components have been identified and characterized, but it remains unclear how these Tic proteins are organized to form a protein-conducting channel or whether a stable Tic core complex that binds translocating preprot ...
... located in the inner and outer envelope membranes. At the inner membrane, many Tic components have been identified and characterized, but it remains unclear how these Tic proteins are organized to form a protein-conducting channel or whether a stable Tic core complex that binds translocating preprot ...
A New Type of a Multifunctional ß
... The biochemical and molecular properties of the -oxidation enzymes from algae have not been investigated yet. The present study provides such data for the phylogenetically old alga Euglena (Euglena gracilis). A novel multifunctional -oxidation complex was purified to homogeneity by ammonium sulfat ...
... The biochemical and molecular properties of the -oxidation enzymes from algae have not been investigated yet. The present study provides such data for the phylogenetically old alga Euglena (Euglena gracilis). A novel multifunctional -oxidation complex was purified to homogeneity by ammonium sulfat ...
A New Type of a Multifunctional ß-Oxidation
... The biochemical and molecular properties of the -oxidation enzymes from algae have not been investigated yet. The present study provides such data for the phylogenetically old alga Euglena (Euglena gracilis). A novel multifunctional -oxidation complex was purified to homogeneity by ammonium sulfat ...
... The biochemical and molecular properties of the -oxidation enzymes from algae have not been investigated yet. The present study provides such data for the phylogenetically old alga Euglena (Euglena gracilis). A novel multifunctional -oxidation complex was purified to homogeneity by ammonium sulfat ...
Interaction of Urea with Amino Acids: Implications for Urea
... especially charged residues interact less frequently with urea, the charged amino acids ASP and GLU show even more interactions with water than with urea. Note that CUW < 1 does not necessarily imply a positive free energy of transfer from water to urea solution, which has been found to be negative ...
... especially charged residues interact less frequently with urea, the charged amino acids ASP and GLU show even more interactions with water than with urea. Note that CUW < 1 does not necessarily imply a positive free energy of transfer from water to urea solution, which has been found to be negative ...
Interactome

In molecular biology, an interactome is the whole set of molecular interactions in a particular cell. The term specifically refers to physical interactions among molecules (such as those among proteins, also known as protein-protein interactions) but can also describe sets of indirect interactions among genes (genetic interactions). Mathematically, interactomes are generally displayed as graphs.The word ""interactome"" was originally coined in 1999 by a group of French scientists headed by Bernard Jacq. Though interactomes may be described as biological networks, they should not be confused with other networks such as neural networks or food webs.